Results overview: Found 2 records in 0.02 seconds.
Articles, 2 records found
Articles 2 records found  
1.
14 p, 7.4 MB Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors / Llinàs-Arias, Pere (Cancer Epigenetics Laboratory, Health Research Institute of the Balearic Islands (IdISBa)) ; Ensenyat-Mendez, Miquel (Cancer Epigenetics Laboratory. Health Research Institute of the Balearic Islands (IdISBa)) ; Íñiguez-Muñoz, Sandra (Cancer Epigenetics Laboratory. Health Research Institute of the Balearic Islands (IdISBa)) ; Orozco, Javier I.J. (Saint John's Cancer Institute, Providence Saint John's Health Center, Santa Monica, CA, USA) ; Valdez, Betsy (Saint John's Cancer Institute, Providence Saint John's Health Center, Santa Monica, CA, USA.) ; Salomon, Matthew P. (University of Southern California, Los Angeles, USA) ; Matsuba, Chikako (University of Southern California, Los Angeles, USA) ; Solivellas-Pieras, Maria (Cancer Epigenetics Laboratory. Health Research Institute of the Balearic Islands (IdISBa)) ; Bedoya-López, Andrés F. (Cancer Epigenetics Laboratory. Health Research Institute of the Balearic Islands (IdISBa)) ; Sesé, Borja (Cancer Epigenetics Laboratory. Health Research Institute of the Balearic Islands (IdISBa)) ; Mezger, Anja (Science for Life Laboratory, Solna, Sweden) ; Ormestad, Mattias (Science for Life Laboratory, Solna, Sweden) ; Unzueta, Fernando (Universitat de Barcelona) ; Strand, Siri H. (Stanford University School of Medicine, Stanford, USA) ; Boiko, Alexander D. (Samuel Oschin Comprehensive Cancer Institute, Los Angeles, USA) ; Hwang, E.Shelley (Duke University School of Medicine, Durham, USA) ; Cortés, Javier (Universidad Europea de Madrid) ; DiNome, Maggie L. (Duke University School of Medicine, Durham, USA) ; Esteller, Manel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Lupien, Mathieu (University of Toronto) ; Marzese, Diego M. (Cancer Epigenetics Laboratory, Health Research Institute of the Balearic Islands (IdISBa))
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype that exhibits a high incidence of distant metastases and lacks targeted therapeutic options. Here we explored how the epigenome contributes to matrix metalloprotease (MMP) dysregulation impacting tumor invasion, which is the first step of the metastatic process. [...]
2023 - 10.1186/s12943-023-01906-8
Molecular cancer, Vol. 22 Núm. 1 (november 2023)  
2.
28 p, 5.4 MB BarkBase : Epigenomic Annotation of Canine Genomes / Megquier, Kate (Vertebrate Genomics, Broad Institute of MIT and Harvard, Cambridge.) ; Genereux, Diane P. (Broad Institute of MIT and Harvard) ; Hekman, Jessica (Broad Institute of MIT and Harvard) ; Swofford, Ross (Broad Institute of MIT and Harvard) ; Turner-Maier, Jason (Broad Institute of MIT and Harvard) ; Johnson, Jeremy (Broad Institute of MIT and Harvard) ; Alonso, Jacob (Broad Institute of MIT and Harvard) ; Li, Xue (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Morrill, Kathleen (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Anguish, Lynne J. (Cornell University. Baker Institute for Animal Health) ; Koltookian, Michele (Broad Institute of MIT and Harvard) ; Logan, Brittney (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ; Sharp, Claire R. (Murdoch University. School of Veterinary and Life Sciences) ; Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry & Microbiology) ; Meyers-Wallen, Vicki N. (Cornell University. Baker Institute for Animal Health) ; Hoffman, Andrew (Tufts University. Cummings School of Veterinary Medicine) ; Karlsson, Elinor K. (University of Massachusetts Medical School. Program in Molecular Medicine)
Dogs are an unparalleled natural model for investigating the genetics of health and disease, particularly for complex diseases like cancer. Comprehensive genomic annotation of regulatory elements active in healthy canine tissues is crucial both for identifying candidate causal variants and for designing functional studies needed to translate genetic associations into disease insight. [...]
2019 - 10.3390/genes10060433
Genes, Vol. 10 (june 2019)  

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