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12 p, 5.7 MB |
Protein-only Nanoparticles for T Cell Expansion and Activation
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Fornt Suñé, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Lázaro Bermejo, Gonzalo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Gil Garcia, Marcos (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Aran, Andrea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Garcia-Pardo, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Martí, Mercè (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The in vitro expansion and activation of T cells utilizing synthetic nanosized artificial antigen presenting cells (aAPCs) have emerged as a promising technique for cancer treatment. Although diverse nanomaterials have been explored as aAPC scaffolds, protein-only nanoparticles have been largely overlooked, despite their high designability and biocompatibility. [...]
2024 -  10.1021/acsanm.4c00698
ACS applied nano materials, Vol. 7 Núm. 6 (22 2024) , p. 6669-6680
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25 p, 6.8 MB |
Role of Ion Channels in the Maintenance of Sperm Motility and Swimming Behavior in a Marine Teleost
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Castro-Arnau, Júlia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Chauvigné, François (Institut de Ciències del Mar) ;
Cerdà, Joan (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
In oviparous marine fishes, the hyperosmotic induction of sperm motility in seawater (SW) is well established, however, the potential function of ion channels in the maintenance of post activated spermatozoon swimming performance remains largely unknown. [...]
2022 - 10.3390/ijms232012113
International journal of molecular sciences, Vol. 23, Issue 20 (October 2022) , art. 12113
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21 p, 14.7 MB |
Interaction of Iron Oxide Nanoparticles with Macrophages Is Influenced Distinctly by "Self" and "Non-Self" Biological Identities
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Portilla, Yadileiny (Department of Immunology and Oncology and Nanobiomedicine Initiative. Centro Nacional de Biotecnología (CNB-CSIC)) ;
Mulens-Arias, Vladimir (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Daviu, Neus (Centro Nacional de Biotecnología) ;
Paradela, Alberto (Centro Nacional de Biotecnología) ;
Pérez Yagüe, Sonia (Department of Immunology and Oncology and Nanobiomedicine Initiative. Centro Nacional de Biotecnología (CNB-CSIC)) ;
Barber, Domingo F. (Centro Nacional de Biotecnología)
Upon contact with biological fluids like serum, a protein corona (PC) complex forms on iron oxide nanoparticles (IONPs) in physiological environments and the proteins it contains influence how IONPs act in biological systems. [...]
2023 - 10.1021/acsami.3c05555
ACS applied materials & interfaces, Vol. 15 Núm. 30 (february 2023) , p. 35906-35926
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8 p, 664.1 KB |
Cardiac activation-repolarization patterns and ion channel expression mapping in intact isolated normal human hearts
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Opthof, Tobias (University Medical Center Utrecht) ;
Remme, Carol Ann (Heart Center Amsterdam) ;
Jorge, Esther (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Noriega, Francisco (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Wiegerinck, Rob F. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Tasiam, Arlin (Heart Center Amsterdam) ;
Beekman, Leander (Heart Center Amsterdam) ;
Alvarez-Garcia, Jesus (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Munoz-Guijosa, Cristian (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Coronel, Ruben (Fondation Bordeaux Université) ;
Cinca, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The repolarization pattern of the human heart is unknown. The purpose of this study was to perform a multisite analysis of the activation-repolarization patterns and mRNA expression patterns of ion channel subunits in isolated human hearts. [...]
2017 - 10.1016/j.hrthm.2016.10.010
Heart Rhythm, Vol. 14 Núm. 2 (january 2017) , p. 265-272
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19 p, 826.8 KB |
Efficacy of videoconference group acceptance and commitment therapy (ACT) and behavioral activation therapy for depression (BATD) for chronic low back pain (CLBP) plus comorbid depressive symptoms : a randomized controlled trial (IMPACT Study)
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Sanabria-Mazo, Juan P. (Parc Sanitari Sant Joan de Déu) ;
Colomer-Carbonell, Ariadna (Parc Sanitari Sant Joan de Déu) ;
Borràs, Xavier (Universitat Autònoma de Barcelona) ;
Castaño Asins, Juan Ramon (Hospital del Mar (Barcelona, Catalunya)) ;
McCracken, Lance M (Uppsala Universitet) ;
Montero-Marin, Jesus (Parc Sanitari Sant Joan de Déu) ;
Pérez-Aranda, Adrián (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Edo Izquierdo, Sílvia (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Sanz Ruiz, Antoni (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Feliu-Soler, Albert (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Luciano, Juan V (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
This study examined the efficacy of adding a remote, synchronous, group, videoconference-based form of acceptance and commitment therapy (ACT) or behavioral activation therapy for depression (BATD) to treatment-as-usual (TAU) in 234 patients with chronic low back pain (CLBP) plus comorbid depressive symptoms. [...]
2023 - doi.org/10.1016/j.jpain.2023.04.008
The Journal of Pain, Vol. 24 Núm. 8 (2023) , p. 1522-1540
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10 p, 205.2 KB |
Las singularidades del archivo
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Acebal, Martín
El artículo estudia el archivo como práctica social y como proceso semiótico. La primera perspectiva se apoya en la noción de práctica de Althusser y propone reconocer tres prácticas de archivo articuladas: una práctica teórica, una material y una política. [...]
The article studies the archive as a social practice and as a semiotic process. The first perspective is based on Althusser's notion of practice and proposes to recognize three articulated archival practices: a theoretical practice, a material one, and a political one. [...]
2023 - 10.35659/designis.i39p67-76
DeSignis, Núm. 39 (2023) , p. 67-76
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10 p, 712.3 KB |
Shared decision making in patients with substance use disorders : A one-year follow-up study
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Serrano-Pérez, Pedro (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Rivero-Santana, Amado (Fundación Canaria Instituto de Investigación Sanitaria de Canarias) ;
Daigre, Constanza (Hospital Universitari Vall d'Hebron) ;
Palma-Álvarez, Raúl Felipe (Hospital Universitari Vall d'Hebron) ;
Nistal-Franco, Icía (Hospital Álvaro Cunqueiro (Vigo)) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Grau-López, Lara (Hospital Universitari Vall d'Hebron)
Patient-centered care in therapeutic processes has been associated with better clinical outcomes, however, it remains a poorly studied aspect in Substance Use Disorder (SUD). The study aimed to evaluate patient's preferences, perceived participation in treatment decisions and activation level; and how they predict retention, pharmacological adherence and substance use during one-year follow-up. [...]
2023 - 10.1016/j.psychres.2023.115540
Psychiatry research, Vol. 329 (2023) , p. 115540
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12 p, 3.7 MB |
Skewed Cellular Distribution and Low Activation of Functional T-Cell Responses in SARS-CoV-2 Non-Seroconvertors
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Kilpeläinen, Athina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Jiménez-Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanch-Lombarte, Oscar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Peña, Ruth (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Quirant, Bibiana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez-Caballero, Raúl (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Chamorro, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Massanella, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
The role of T cells in the control of SARS-CoV-2 infection has been underestimated in favor of neutralizing antibodies. However, cellular immunity is essential for long-term viral control and protection from disease severity. [...]
2022 - 10.3389/fimmu.2022.815041
Frontiers in immunology, Vol. 13 (may 2022)
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15 p, 1.9 MB |
Labile Base-Stabilized Silyliumylidene Ions. Non-Metallic Species Capable of Activating Multiple Small Molecules
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Nougué, Raphaël (Université de Toulouse) ;
Takahashi, Shintaro (Université de Toulouse) ;
Dajnak, Aymeric (Université de Toulouse) ;
Maerten, Eddy (Université de Toulouse) ;
Baceiredo, Antoine (Université de Toulouse) ;
Saffon-Merceron, Nathalie (Institut de Chimie de Toulouse) ;
Branchadell Gallo, Vicenç (Universitat Autònoma de Barcelona. Departament de Química) ;
Kato, Tsuyoshi (Université de Toulouse)
Several base-stabilized silyliumylidene ions (2 and 3) with different ligands were synthesized. Their behaviour appeared strongly dependent on the nature of ligand. Indeed, in contrast to the poorly reactive silyliumylidene ions 3 c,d stabilized by strongly donating ligands (DMAP, NHC), the silylene- and sulfide-supported one (2-H and 3 a) exhibits higher reactivity toward various small molecules. [...]
2022 - 10.1002/chem.202202037
Chemistry, Vol. 28, Issue 70 (December 2022) , art. e202202037
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