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Documents de recerca, 13 registres trobats
Articles 50 registres trobats  1 - 10següentfinal  anar al registre:
1.
12 p, 772.4 KB Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3 / Giménez Llort, Lydia (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Santana-Santana, Mikel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Ratia, Míriam (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pérez, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Camps García, Pelayo (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Laboratori de Química Farmacèutica) ; Badia Sancho, Albert (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Clos, Victòria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
A new hypothesis highlights sleep-dependent learning/memory consolidation and regards the sleep-wake cycle as a modulator of β-amyloid and tau Alzheimer's disease (AD) pathologies. Sundowning behavior is a common neuropsychiatric symptom (NPS) associated with dementia. [...]
2021 - 10.3390/brainsci11040426
Brain sciences, Vol. 11 Núm. 4 (2021) , p. 426  
2.
13 p, 1.2 MB Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR-127 in aged animals / Loppi, Sanna (University of Arizona) ; Korhonen, Paula (University of Eastern Finland) ; Bouvy-Liivrand, Maria (University of Eastern Finland) ; Caligola, Simone (University of Verona) ; Turunen, Tiia A. (University of Eastern Finland) ; Turunen, Mikko P. (University of Eastern Finland) ; Hernandez de Sande, Ana (University of Eastern Finland) ; Kołosowska, Natalia (University of Eastern Finland) ; Scoyni, Flavia (University of Eastern Finland) ; Rosell Novel, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lemarchant, Sighild (University of Eastern Finland) ; Dhungana, Hiramani (University of Helsinki) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Koistinaho, Jari (University of Helsinki) ; Kanninen, Katja M. (University of Eastern Finland) ; Kaikkonen, Minna U. (University of Eastern Finland) ; Giugno, Rosalba (University of Verona) ; Heinäniemi, Merja (University of Eastern Finland) ; Malm, Tarja (University of Eastern Finland) ; Universitat Autònoma de Barcelona
Ischemic stroke, the third leading cause of death in the Western world, affects mainly the elderly and is strongly associated with comorbid conditions such as atherosclerosis or diabetes, which are pathologically characterized by increased inflammation and are known to influence the outcome of stroke. [...]
2020 - 10.1111/acel.13287
Aging Cell, Vol. 20 (december 2020)  
3.
13 p, 534.4 KB Depressive symptoms, fatigue and social relationships influenced physical activity in frail older community-dwellers during the Spanish lockdown due to the COVID-19 pandemic / Pérez, Laura Mónica (Parc Sanitari Pere Virgili (Barcelona)) ; Castellano Tejedor, Carmina (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Cesari, Matteo (Università di Milano) ; Soto-Bagaria, Luis (Parc Sanitari Pere Virgili (Barcelona)) ; Ars, Joan (Parc Sanitari Pere Virgili (Barcelona)) ; Zambom-Ferraresi, Fabricio (Universidad Pública de Navarra) ; Baró, Sonia (Parc Sanitari Pere Virgili (Barcelona)) ; Díaz-Gallego, Francisco (Institut Català de la Salut. Centre d'Atenció Primària Bordeta-Magòria) ; Vilaró, Jordi (Universitat Ramon Llull. Departament de Ciències de la Salut) ; Enfedaque, María B. (Institut Català de la Salut. Gerència de Barcelona) ; Espí-Valbé, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Inzitari, Marco (Universitat Autònoma de Barcelona. Departament de Medicina)
Due to the dramatic impact of the COVID-19 pandemic, Spain underwent a strict lockdown (March-May 2020). How the lockdown modified older adults' physical activity (PA) has been poorly described. This research assesses the effect of the lockdown on PA levels and identifies predictors of sufficient/insufficient PA in frail older community-dwellers. [...]
2021 - 10.3390/ijerph18020808
International journal of environmental research and public health, Vol. 18, núm. 2 (2021) , p. 808  
4.
21 p, 2.7 MB Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients / Chen, C. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Wei, Y. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Lin, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Lai, L. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Shen, S. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Su, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Shafer, A. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Fleischer, T. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Bjaanæs, M.M. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Wang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zhang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Chen, F. (Jiangsu Key Lab of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, D.C. (Pulmonary and Critical Care Division. Department of Medicine. Massachusetts General Hospital and Harvard Medical School) ; Universitat Autònoma de Barcelona
DNA methylation changes during aging, but it remains unclear whether the effect of DNA methylation on lung cancer survival varies with age. Such an effect could decrease prediction accuracy and treatment efficacy. [...]
2020 - 10.18632/aging.103284
Aging (Albany NY), Vol. 12 Núm. 11 (15 2020) , p. 10642-10662  
5.
9 p, 2.9 MB Happiness and life expectancy by main occupational position among older workers : who will live longer and happy? / Lozano Riera, Mariona (Centre d'Estudis Demogràfics) ; Solé-Auró, Aïda (Universitat Pompeu Fabra. Departament de Ciències Polítiques i Socials)
Current concerns about aging populations are being translated into legislations to postpone the statutory age at retirement. However, if this is done without considering inequalities in longevity across occupational groups, some may face higher vulnerabilities than others. [...]
2021 - 10.1016/j.ssmph.2021.100735
SSM - Population Health, Vol. 13 (january 2021)  
6.
3 p, 1.7 MB National age and coresidence patterns shape COVID-19 vulnerability / Esteve, Albert (Centre d'Estudis Demogràfics) ; Permanyer, Iñaki (Universitat Autònoma de Barcelona. Centre d'Estudis Demogràfics) ; Boertien, Diederik (Universitat Autònoma de Barcelona. Centre d'Estudis Demogràfics) ; Vaupel, James W. (University of Southern Denmark)
Based on harmonized census data from 81 countries, we estimate how age and coresidence patterns shape the vulnerability of countries' populations to outbreaks of coronavirus disease 2019 (COVID-19). We estimate variation in deaths arising due to a simulated random infection of 10% of the population living in private households and subsequent within-household transmission of the virus. [...]
2020 - 10.1073/pnas.2008764117
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117 (june 2020) , p. 16118-16120  
7.
14 p, 2.3 MB Delayed γH2AX foci disappearance in mammary epithelial cells from aged women reveals an age-associated DNA repair defect / Anglada, Teresa (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Repullés, Joan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Espinal, Anna (Universitat Autònoma de Barcelona. Servei d'Estadística Aplicada) ; LaBarge, Mark A (Lawrence Berkeley National Laboratory) ; Stampfer, Martha R (Lawrence Berkeley National Laboratory) ; Genescà, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martín, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Institut d'Investigació Biomèdica Sant Pau
Aging is a degenerative process in which genome instability plays a crucial role. To gain insight into the link between organismal aging and DNA repair capacity, we analyzed DNA double-strand break (DSB) resolution efficiency in human mammary epithelial cells from 12 healthy donors of young and old ages. [...]
2019 - 10.18632/aging.101848
Aging (Albany NY), Vol. 11, Num. 5 (March 2019) , p. 1510-1523  
8.
8 p, 913.5 KB Community intervention to reduce social isolation in older adults in disadvantaged urban areas : study protocol for a mixed methods multi-approach evaluation / López, María José (Agència de Salut Pública de Barcelona) ; Lapena, Carolina (Centre d'Atenció Primària Sanllehy) ; Sánchez, Alba (Hospital Universitari de Bellvitge) ; Continente, Xavier (Institut d'Investigació Biomèdica Sant Pau) ; Fernández, Ana (Agència de Salut Pública de Barcelona) ; Universitat Autònoma de Barcelona
The proportion of older people has dramatically increased in recent decades. Moreover, social and demographic trends show a global increase of older people at risk of loneliness and lack of social relationships. [...]
2019 - 10.1186/s12877-019-1055-9
BMC geriatrics, Vol. 19 (february 2019)  
9.
9 p, 1.0 MB Effect of Cd(II) on the ripening of ferrihydrite in alkaline media / Alvarez, Mariana (Universidad Nacional del Sur. Departamento de Química) ; Horst, María Fernanda (Universidad Nacional del Sur. Departamento de Química) ; Sileo, Elsa E. (Universidad de Buenos Aires. Departamento de Química Inorgánica) ; Rueda, Elsa H. (Universidad Nacional del Sur. Departamento de Química)
To acquire a better understanding of the influence exerted by the presence of Cd during the process of transforming ferrihydrite to goethite, the morphological and structural changes of several samples obtained by the addition of Cd to a suspension of nascent goethite were explored, and their chemical reactivity in acid media assessed. [...]
2012 - 10.1346/CCMN.2012.0600201
Clays and Clay Minerals, Vol. 60, Núm. 2 (2012) , p. 99-107  
10.
27 p, 3.0 MB A multiscale model of epigenetic heterogeneity-driven cell fate decision-making / Folguera Blasco, Núria (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Pérez Carrasco, Rubén (University College London. Department of Mathematics) ; Cuyàs, Elisabet (Institut d'Investigació Biomèdica de Girona) ; Menendez, Javier A. (Institut d'Investigació Biomèdica de Girona) ; Alarcón Cor, Tomás (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Universitat Autònoma de Barcelona. Centre de Recerca Matemàtica
The inherent capacity of somatic cells to switch their phenotypic status in response to damage stimuli in vivo might have a pivotal role in ageing and cancer. However, how the entryexit mechanisms of phenotype reprogramming are established remains poorly understood. [...]
2019 - 10.1371/journal.pcbi.1006592
PLoS computational biology, Vol. 15, Issue 4 (April 2019) , art. e1006592  

Articles : 50 registres trobats   1 - 10següentfinal  anar al registre:
Documents de recerca 13 registres trobats  1 - 10següent  anar al registre:
1.
1 p, 3.2 MB Towards healthy aging : the effect of senolytics on age-related diseases / Garcia Baucells, Pau ; Universitat Autònoma de Barcelona. Facultat de Biociències
Cellular senescence is a state of cell cycle arrest that takes place in response to damaging stimuli such as telomere shortening. Despite their short-term beneficial effects, senescent cells have been proven to accumulate during aging, contributing to a wide range of age-related pathologies. [...]
2020
Grau en Ciències Biomèdiques [832]  
2.
34 p, 1.5 MB Envejecer más allá de la edad. Diferencias de género, generación y clase social en salud en la población española / Cámara, Antonio D. ; Zueras Castillo, Pilar ; Trias-Llimós, Sergi ; Blanes, Amand
Se utilizan las ocho ediciones disponibles de la Encuesta Nacional de Salud en España (ENSE, 1987-2011) para analizar tendencias de cohorte y determinantes socioeconómicos en tres indicadores de salud y condiciones de vida: el estado nutricional neto (aproximado por la estatura), las condiciones crónicas cardiovasculares (CCC) y la discapacidad. [...]
S'utilitzen les vuit edicions disponibles de l'Enquesta Nacional de Salut a Espanya (ENSE, 1987-2011) per analitzar tendències de cohort i determinants socioeconòmics en tres indicadors de salut i condicions de vida: l'estat nutricional net, (aproximat per l'alçada), les condicions cròniques cardiovasculars (CCC) i la discapacitat. [...]
The eight available editions of the Spanish National Health Survey (ENSE, 1987-2011) are used to analyze cohort trends and socioeconomic determinants with respect to three indicators of health and living standards: the net nutritional status (based on height), chronic cardiovascular conditions (CCCs) and disability. [...]

Bellaterra : Centre d'Estudis Demogràfics, 2013 (Papers de demografia (Centre d'Estudis Demogràfics) ; 427)  
3.
1 p, 2.0 MB Caloric restriction and aging / Orduña Dolado, Anna ; Casamayor Gracia, Antonio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Aging is characterised by the functional decay of the body and it is one of the prime risks of many pathologies. Caloric restriction is an anti-aging intervention that through the enhancement in repair mechanism and the decrease in the generation of damaging elements allows the postponement of aging and its related pathologies.
2019-05-31
Grau en Bioquímica [814]  
4.
1 p, 1.1 MB Genomic instability as a link between cancer and aging / Sebastián Pérez, Rubén ; Pallarès i Goitiz, Irantzu, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
5.
1 p, 1.2 MB Current status of treatments for cardiovascular aging : are statins a good option? / Navarro Gutiérrez, Judith ; Jiménez Altayó, Francesc, dir. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Ciències Biomèdiques [832]  
6.
1 p, 367.7 KB Hibiscus sabdariffa : a potential strategy to decrease aging-induced cardiovascular risk? / Farré Alins, Víctor ; Jiménez Altayó, Francesc, dir. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
7.
1 p, 276.1 KB Will it be possible to regulate human aging with drugs ? / Sacarès Simon, Bernat ; Pereira dos Santos, Cristina Maria, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Genètica [833]  
8.
1 p, 1002.9 KB The role of shelterin in cellular senescense and systemic aging / Chen, Qian ; Genescà, A., (Anna), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
9.
1 p, 1.5 MB Astrocytes, the new trending topic in aging and neurodegeneration / Valls de Lacalle, Laura ; Masgrau Juanola, Roser, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Bioquímica [814]  
10.
1 p, 774.0 KB The Role of mitochondrial DNA in human aging / García Mulero, Sandra ; Pereira dos Santos, Cristina Maria, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Biologia [812]  

Documents de recerca : 13 registres trobats   1 - 10següent  anar al registre:
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