Resultados globales: 2 registros encontrados en 0.03 segundos.
Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
21 p, 965.2 KB CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline / Suárez‐Calvet, Marc (Ludwig Maximilians Universität München) ; Capell, Anja (Ludwig Maximilians Universität München) ; Araque Caballero, Miguel Ángel (Ludwig Maximilians Universität München) ; Morenas‐Rodríguez, Estrella (Universitat Autònoma de Barcelona) ; Fellerer, Katrin (Ludwig Maximilians Universität München) ; Franzmeier, Nicolai (Ludwig Maximilians Universität München) ; Kleinberger, Gernot (Munich Cluster for Systems Neurology (SyNergy)) ; Eren, Erden (Dokuz Eylul University, Turkey) ; Deming, Yuetiva (Washington University School of Medicine) ; Piccio, Laura (Washington University School of Medicine) ; Karch, Celeste M (Washington University School of Medicine) ; Cruchaga, Carlos (Washington University School of Medicine) ; Paumier, Katrina (Washington University School of Medicine) ; Bateman, Randall J (Washington University School of Medicine) ; Fagan, Anne M (Washington University School of Medicine) ; Morris, John C (Washington University School of Medicine) ; Levin, Johannes (Ludwig Maximilians Universität München) ; Danek, Adrian (Ludwig Maximilians Universität München) ; Jucker, Mathias (University of Tübingen) ; Masters, Colin L (University of Melbourne) ; Rossor, Martin N (UCL Institute of Neurology) ; Ringman, John M (University of Southern California) ; Shaw, Leslie M (University of Pennsylvania) ; Trojanowski, John Q (University of Pennsylvania) ; Weiner, Michael (University of California at San Francisco) ; Ewers, Michael (Ludwig Maximilians Universität München) ; Haass, Christian (Munich Cluster for Systems Neurology (SyNergy))
Progranulin (PGRN) is predominantly expressed by microglia in the brain, and genetic and experimental evidence suggests a critical role in Alzheimer's disease (AD). We asked whether expression is changed in a disease severity‐specific manner in . [...]
2018 - 10.15252/emmm.201809712
EMBO Molecular Medicine, Vol. 10 (november 2018)  
32 p, 913.8 KB Alzheimer's disease biomarkers detection in human samples by efficient capturing through porous magnetic microspheres and labelling with electrocatalytic gold nanoparticles / De la Escosura Muñiz, Alfredo (Institut Català de Nanociència i Nanotecnologia) ; Plichta, Zdeněk (Akademie věd České republiky) ; Horák, Daniel (Akademie věd České republiky) ; Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
A nanobiosensor based on the use of porous magnetic microspheres (PMM) as efficient capturing/pre-concentrating platform is presented for detection of Alzheimer's disease (AD) biomarkers. These PMMs prepared by a multistep swelling polymerization combined with iron oxide precipitation afford carboxyl functional groups suitable for immobilization of antibodies on the particle surface allowing an enhanced efficiency in the capturing of AD biomarkers from human serum samples. [...]
2015 - 10.1016/j.bios.2014.07.086
Biosensors and bioelectronics, Vol. 67 (May 2015) , p. 162-169  

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