No s'ha trobat cap coincidència exacta per Alzheimer’s, però canviant-lo per Alzheimer s...
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Articles, 18 registres trobats
Documents de recerca, 24 registres trobats
Articles 18 registres trobats  1 - 10següent  anar al registre:
1.
11 p, 334.7 KB Survival curves and behavioral profiles of female 3xTg-AD mice surviving to 18-months of age as compared to mice with normal aging / Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; De la Fuente, Mónica (Universidad Complutense de Madrid. Departamento de Fisiología Animal II) ; Giménez Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències)
New evidence reveals a high degree of heterogeneity in Alzheimer's disease (AD) clinical and temporal patterns, supporting the existence of several subgroups of patients. Prognosticators of end-of-life dementia specific to elderly patients are necessary to address this heterogeneity. [...]
2017 - 10.3233/ADR-170011
Journal of Alzheimer's disease reports, Vol. 1, issue 1 (2017) , p. 47-57  
2.
13 p, 787.1 KB Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease / Dekker, Alain D. (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Vermeiren, Yannick (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Carmona-Iragui, Maria (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Benejam, Bessy (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Videla, Laura (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Gelpi, Ellen (Neurological Tissue Bank—Biobanc, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ; Aerts, Tony (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Van Dam, Debby (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Fernández, Susana (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Lleó Bisa, Alberto (Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain) ; Videla, Sebastian (Faculty of Health and Life Sciences, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain) ; Sieben, Anne (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Martin, Jean-Jacques (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; De Deyn, Peter P. (Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium)
People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. [...]
2017 - 10.1016/j.dadm.2017.11.001
Alzheimer's Dementia : Diagnosis, Assessment Disease Monitoring, Vol. 10 (november 2017) , p. 99-111  
3.
23 p, 1.3 MB The behavioral and psychological symptoms of dementia in Down syndrome (BPSD-DS) scale : comprehensive assessment of psychopathology in Down syndrome / Dekker, Alain D. (Universitair Medisch Centrum Groningen) ; Sacco, Silvia (Institut Jérôme Lejeune) ; Carfi, Angelo (Universitá Cattolica del Sacro Cuore) ; Benejam, Bessy (Fundació Catalana Síndrome de Down) ; Vermeiren, Yannick (Universitair Medisch Centrum Groningen) ; Beugelsdijk, Gonny (Ipse de Bruggen) ; Schippers, Mieke (Ipse de Bruggen) ; Hassefras, Lyanne (Ipse de Bruggen) ; Eleveld, José (Cosis (Groningen)) ; Grefelman, Sharina (Cosis (Groningen)) ; Fopma, Roelie (Talant (Heerenveen)) ; Bomer-Veenboer, Monique (Pameijer (Rotterdam)) ; Boti, Mariángeles (Fundació Catalana Síndrome de Down) ; Oosterling, G. Danielle E. (Aveleijn (Borne)) ; Scholten, Esther (Elver (Nieuw-Wehl)) ; Tollenaere, Marleen (Institute Born-Bunge) ; Checkley, Laura (University College London. Division of Psychiatry) ; Strydom, André (University College London. Division of Psychiatry) ; Van Goethem, Gert (Het GielsBos (Gierle)) ; Onder, Graziano (Universitá Cattolica del Sacro Cuore) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; zu Eulenburg, Christine (Universitair Medisch Centrum Groningen) ; Coppus, Antonia M.W. (Dichterbij (Gennep)) ; Rebillat, Anne-Sophie (Institut Jérôme Lejeune) ; Fortea, Juan (Fundació Catalana Síndrome de Down) ; De Deyn, Peter P. (Universitair Medisch Centrum Groningen) ; Universitat Autònoma de Barcelona
People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD). Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not been comprehensively evaluated in DS. [...]
2018 - 10.3233/JAD-170920
Journal of Alzheimer's disease, Vol. 63, issue 2 (2018) , p. 797-819  
4.
12 p, 2.4 MB The antigen-binding fragment of human gamma immunoglobulin prevents amyloid β-peptide folding into β-sheet to form oligomers / Valls-Comamala, Victòria (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular) ; Guivernau, Biuse (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular) ; Bonet, Jaume (Universitat Pompeu Fabra. Unitat de Recerca en Informàtica Biomèdica (GRIB)) ; Puig, Marta (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular) ; Perálvarez Marín, Àlex (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Palomer, Ernest (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular) ; Fernàndez-Busquets, Xavier (Institut de Bioenginyeria de Catalunya (IBEC)) ; Altafaj, Xavier (Universitat de Barcelona. Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)) ; Tajes, Marta (Institut d'Investigació Mèdica Hospital del Mar (IMIM)) ; Puig-Pijoan, Albert (Parc de Salut Mar. Hospital del Mar (IMI) ; Vicente, Rubén (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular) ; Oliva, Baldomero (Universitat Pompeu Fabra. Unitat de Recerca en Informàtica Biomèdica (GRIB)) ; Muñoz, Francisco J. (Universitat Pompeu Fabra. Laboratori de Fisiologia Molecular)
The amyloid beta-peptide (Aβ) plays a leading role in Alzheimer's disease (AD) physiopathology. Even though monomeric forms of Aβ are harmless to cells, Aβ can aggregate into β-sheet oligomers and fibrils, which are both neurotoxic. [...]
2017 - 10.18632/oncotarget.17074
Oncotarget, Vol. 8, Num. 25 (June 2017) , p. 41154-41165  
5.
10 p, 566.6 KB Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome / Dekker, Alain D. (University of Antwerp) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; De Deyn, Peter P. (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ; Universitat Autònoma de Barcelona
Down syndrome (DS), present in nearly six million people, is associated with an extremely high risk to develop Alzheimer's disease (AD). Amyloid-β and tau pathology are omnipresent from age 40 years onward, but clinical symptoms do not appear in all DS individuals. [...]
2017 - 10.1016/j.dadm.2017.02.006
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 8 (march 2017) , p. 1-10  
6.
9 p, 204.1 KB Effect Size Analyses of Souvenaid in Patients with Alzheimer's Disease / Cummings, Jeffrey (Cleveland Clinic Lou Ruvo Center for Brain Health) ; Scheltens, Philip (VU University Medical Center) ; McKeith, Ian (Newcastle University) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Harrison, John E. (Metis Cognition Ltd, Park House, Kilmington Common, Wiltshire) ; Bertolucci, Paulo H.F. (Behaviour Neurology Section – Universidade Federal de São Paulo) ; Rockwood, Kenneth (DGI Clinical, Halifax, NS) ; Wilkinson, David (University of Southampton) ; Wijker, Wouter (Auxiliis BV, Amsterdam) ; Bennett, David A. (Rush University Medical Center) ; Shah, Raj C. (Rush University Medical Center) ; Universitat Autònoma de Barcelona. Departament de Neurologia
Background: Souvenaid ® (uridine monophosphate, docosahexaenoic acid, eicosapentaenoic acid, choline, phospholipids, folic acid, vitamins B12, B6, C, and E, and selenium), was developed to support the formation and function of neuronal membranes. [...]
2016 - 10.3233/JAD-160745
Journal of Alzheimer's Disease, Vol. 55 (december 2016) , p. 1131-1139  
7.
24 p, 5.9 MB Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease / Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Esteban, Gerard (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fogel, Wieslawa A. (Medical University of Lodz. Department of Hormone Biochemistry) ; Ramsay, Rona R. (University of St Andrews. Biomedical Sciences Research Complex) ; Youdim, Moussa B. H. (Ruth and Bruce Rappaport Faculty of Medicine. Department of Pharmacology) ; Tipton, Keith F. (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Marco-Contelles, José (Spanish National Research Council. Institute of General Organic Chemistry) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
HIGHLIGHTS Alzheimer's disease (AD), the most common form of adult onset dementia, is an age-related neurodegenerative disorder characterized by progressive memory loss, decline in language skills, and other cognitive impairments. [...]
2016 - 10.3389/fnins.2016.00205
Frontiers in Neuroscience, Vol. 10 (May 2016) , art. 205  
8.
12 p, 653.6 KB APOE -by-sex interactions on brain structure and metabolism in healthy elderly controls / Sampedro, Frederic (Institut d'Investigació Biomèdica Sant Pau) ; Vilaplana, Eduard (Institut d'Investigació Biomèdica Sant Pau) ; de Leon, Mony J (New York University School of Medicine, New York, NY, USA) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ; Carmona-Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Saudinos, María-Belén (Institut d'Investigació Biomèdica Sant Pau) ; Antón-Aguirre, Sofía (Institut d'Investigació Biomèdica Sant Pau) ; Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Camacho, Valle (Institut d'Investigació Biomèdica Sant Pau) ; Falcón, Carles (Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine - CIBER-BBN, Barcelona, Spain) ; Pavía, Javier (Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine - CIBER-BBN, Barcelona, Spain) ; Ros, Domènec (Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine - CIBER-BBN, Barcelona, Spain) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Lleó Bisa, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
The APOE effect on Alzheimer Disease (AD) risk is stronger in women than in men but its mechanisms have not been established. We assessed the APOE -by-sex interaction on core CSF biomarkers, brain metabolism and structure in healthy elderly control individuals (HC). [...]
2015 - 10.18632/oncotarget.5185
Oncotarget, Vol. 6 (september 2015) , p. 26663-26674  
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12 p, 841.2 KB Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility / Sevlever, Daniel (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Zou, Fanggeng (Human Genetics Division, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio) ; Ma, Li (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Carrasquillo, Sebastian (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Crump, Michael G (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Culley, Oliver J (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Hunter, Talisha A (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Bisceglio, Gina D (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Younkin, Linda (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Allen, Mariet (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Carrasquillo, Minerva M (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Sando, Sigrid B (Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway) ; Aasly, Jan O (Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway) ; Dickson, Dennis W (Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville) ; Graff-Radford, Neill R (Department of Neurology, Mayo Clinic College of Medicine, Jacksonville) ; Petersen, Ronald C (Department of Neurology and the Mayo Alzheimer Disease Research Center, Mayo Clinic College of Medicine, Rochester, Minnesota) ; Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ; Institut d'Investigació Biomèdica Sant Pau
Ajuts: Programa Miguel Servet de l'Instituto de Salud Carlos III i FEDER (European Funds for Regional Development).
Alzheimer's disease is a neurodegenerative disorder in which extracellular deposition of β-amyloid (Aβ) oligomers causes synaptic injury resulting in early memory loss, altered homeostasis, accumulation of hyperphosphorylated tau and cell death. [...]

2015 - 10.1186/s13024-015-0015-x
Molecular Neurodegeneration, Vol. 10 (april 2015)  
10.
13 p, 1.8 MB Interleukin-6, a Major Cytokine in the Central Nervous System / Erta, María (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Quintana, Albert (University of Washington. Departament of Chemistry) ; Hidalgo, Juan (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia
Interleukin-6 (IL-6) is a cytokine originally identified almost 30 years ago as a B-cell differentiation factor, capable of inducing the maturation of B cells into antibody-producing cells. As with many other cytokines, it was soon realized that IL-6 was not a factor only involved in the immune response, but with many critical roles in major physiological systems including the nervous system. [...]
2012 - 10.7150/ijbs.4679
International Journal of Biological Sciences, Vol. 8, Num. 9 (2012) , p. 1254-1266  

Articles : 18 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 24 registres trobats  1 - 10següentfinal  anar al registre:
1.
1 p, 943.6 KB Astrocytes and Alzheimer's disease : the amyloid-β clearance / Compte Sancerni, Sara ; Masgrau Juanola, Roser, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Graduat o Graduada en Bioquímica [814]  
2.
1 p, 356.7 KB Alterations of astrocytic glutamate regulation in Alzheimer disease / Burgaya Julià, Mar ; Masgrau Juanola, Roser, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Graduat o Graduada en Bioquímica [814]  
3.
1 p, 516.2 KB Protective and pathological role of microglia in Alzheimer's disease / Ramos-Roda, Alejandro ; Villegas Hernández, Sandra, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Graduat o Graduada en Biologia [812]  
4.
1 p, 1.2 MB IL-6 and neuroinflammation : a cause and a consequence of Alzheimer’s disease / Mogas Barcons, Aina ; Molinero Egea, María Amalia, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biologia [812]  
5.
1 p, 593.0 KB Adult neurogenesis and alzheimer's disease : what can we learn? / Adame Castillo, Cristina ; Martí Clua, Joaquín, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel•lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biologia [812]  
6.
1 p, 642.9 KB Gene therapy strategies for Alzheimer disease / Heras Vila, Francesc d'Assís de las ; Villaverde Corrales, Antonio, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Bioquímica [814]  
7.
1 p, 776.4 KB The Alzheimer’s disease : the unsolved puzzle / Jolis Orriols, Núria ; Molinero Egea, María Amalia, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Biologia [812]  
8.
1 p, 1.1 MB Biomarkers of Alzheimer's disease : in search of a non-invasive diagnosis / Barlabé Ginesta, Paula ; Barquinero, J. F., (Joan Francesc), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
9.
1 p, 2.1 MB Imaging biomarkers for Alzheimer's disease / Menacho Pando, Carmen María ; Barquinero, J. F., (Joan Francesc), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  
10.
1 p, 738.6 KB Epigenetics as biomarker for Alzheimer's disease : a new approach to prevention, diagnosis and treatment / Martínez Ruiz, Elena ; Barquinero, J. F., (Joan Francesc), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Graduat o Graduada en Ciències Biomèdiques [832]  

Documents de recerca : 24 registres trobats   1 - 10següentfinal  anar al registre:
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