Resultats globals: 8 registres trobats en 0.02 segons.
Articles, 7 registres trobats
Documents de recerca, 1 registres trobats
Articles 7 registres trobats  
1.
13 p, 955.5 KB TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis / van der Zee, Julie (University of Antwerp) ; Gijselinck, Ilse (University of Antwerp) ; Van Mossevelde, Sara (Antwerp University Hospital) ; Perrone, Federica (University of Antwerp) ; Dillen, Lubina (University of Antwerp) ; Heeman, Bavo (University of Antwerp) ; Bäumer, Veerle (University of Antwerp) ; Engelborghs, Sebastiaan (Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken) ; De Bleecker, Jan (University Hospital Ghent and University of Ghent) ; Baets, Jonathan (Antwerp University Hospital) ; Gelpi, Ellen (Neurological Tissue Bank of the Biobanc ‐ Hospital Clinic‐Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS)) ; Rojas García, Ricardo (Universitat Autònoma de Barcelona) ; Clarimon, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Lleó Bisa, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Diehl‐Schmid, Janine (Technische Universität München) ; Alexopoulos, Panagiotis (Technische Universität München) ; Perneczky, Robert (West London Mental Health Trust) ; Synofzik, Matthis (German Research Center for Neurodegenerative Diseases (DZNE)) ; Just, Jennifer (German Research Center for Neurodegenerative Diseases (DZNE)) ; Schöls, Ludger (German Research Center for Neurodegenerative Diseases (DZNE)) ; Graff, Caroline (Karolinska University Hospital) ; Thonberg, Håkan (Karolinska University Hospital) ; Borroni, Barbara (University of Brescia) ; Padovani, Alessandro (University of Brescia) ; Jordanova, Albena (Medical University‐Sofia) ; Sarafov, Stayko (Medical University‐Sofia) ; Tournev, Ivailo (New Bulgarian University) ; de Mendonça, Alexandre (University of Lisbon) ; Miltenberger‐Miltényi, Gabriel (University of Lisbon) ; Simões do Couto, Frederico (University of Lisbon) ; Ramirez, Alfredo (University of Cologne) ; Jessen, Frank (German Center for Neurodegenerative Diseases (DZNE)) ; Heneka, Michael T. (University of Bonn) ; Gómez‐Tortosa, Estrella (Fundación Jiménez Díaz) ; Danek, Adrian (German Center for Neurodegenerative Diseases (DZNE)) ; Cras, Patrick (Antwerp University Hospital) ; Vandenberghe, Rik (University Hospitals Leuven) ; De Jonghe, Peter (Antwerp University Hospital) ; De Deyn, Peter P. (Hospital Network Antwerp) ; Sleegers, Kristel (University of Antwerp) ; Cruts, Marc (University of Antwerp) ; Van Broeckhoven, Christine (University of Antwerp) ; Goeman, Johan (Hospital Network Antwerp) ; Nuytten, Dirk (Hospital Network Antwerp) ; Smets, Katrien (Antwerp University Hospital) ; Robberecht, Wim (University Hospitals Leuven Gasthuisberg) ; Damme, Philip Van (University Hospitals Leuven Gasthuisberg) ; Bleecker, Jan De (University Hospital Ghent) ; Santens, Patrick (University Hospital Ghent) ; Dermaut, Bart (University Hospital Ghent) ; Versijpt, Jan (University Hospital Brussels) ; Michotte, Alex (University Hospital Brussels) ; Ivanoiu, Adrian (Saint‐Luc University Hospital) ; Deryck, Olivier (General Hospital Sint‐Jan Brugge) ; Bergmans, Bruno (General Hospital Sint‐Jan Brugge) ; Delbeck, Jean (General Hospital Sint‐Maria) ; Bruyland, Marc (General Hospital Glorieux Ronse) ; Willems, Christiana (Jessa Hospital) ; Salmon, Eric (University of Liège and Memory Clinic) ; Pastor, Pau (CIBERNED Instituto de Salud Carlos III) ; Ortega‐Cubero, Sara (Deparment of Neurology, Complejo Asistencial Universitario de Palencia) ; Benussi, Luisa (Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Ghidoni, Roberta (Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Binetti, Giuliano (MAC Memory Center and Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Hernández, Isabel (Fundació ACE, Institut Català de Neurociències Aplicades) ; Boada Rovira, Mercè (Fundació ACE, Institut Català de Neurociències Aplicades) ; Ruiz Laza, Agustín (Fundació ACE, Institut Català de Neurociències Aplicades) ; Sorbi, Sandro (Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence) ; Nacmias, Benedetta (Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence) ; Bagnoli, Silvia (Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence) ; Sorbi, Sandro (IRCCS Don Carlo Gnocchi Scandicci) ; Sánchez Valle, Raquel (Hospital Clínic, IDIBAPS) ; Lladó, Albert (Hospital Clínic, IDIBAPS) ; Santana, Isabel (University of Coimbra) ; Rosário Almeida, Maria (University of Coimbra) ; Frisoni, Giovanni B (Hôpitaux Universitaires de Genève et Université de Genève, Genève, Switzerland and IRCCS Fatebenefratelli) ; Maetzler, Walter (Hertie Institute for Clinical Brain Research) ; Matej, Radoslav (Thomayer Hospital, Prague and Charles University) ; Fraidakis, Matthew J. (NeuroRARE Centre for Rare and Genetic Neurological & Neuromuscular Diseases & Neurogenetics) ; Kovacs, Gabor G. (Medical University of Vienna) ; Fabrizi, Gian Maria (University of Verona) ; Testi, Silvia (University of Verona)
We investigated the mutation spectrum of the TANK‐Binding Kinase 1 (TBK1) gene and its associated phenotypic spectrum by exonic resequencing of TBK1 in a cohort of 2,538 patients with frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), or FTD plus ALS, ascertained within the European Early‐Onset Dementia Consortium. [...]
2017 - 10.1002/humu.23161
Human Mutation, Vol. 38, Issue 3 (March 2017) , p. 297-309  
2.
11 p, 1.2 MB Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1 G93A ALS mice : overlapping effects or limited therapeutic opportunity? / Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Del Valle i Macià, Jaume (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Morell, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pallàs i Llibería, Mercè (Universitat de Barcelona. Institut de Biomedicina) ; Osta, Rosario (Universidad de Zaragoza) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease characterized by the loss of motoneurons (MNs) in the spinal cord, brainstem and motor cortex, causing progressive paralysis and death. [...]
2014 - 10.1186/1750-1172-9-78
Orphanet Journal of Rare Diseases, Vol. 9 (May 2014) , art. 78  
3.
14 p, 11.1 MB Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis / Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Herrando Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Manzano, Raquel (Universidad de Zaragoza) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Osta, Rosario (Universidad de Zaragoza) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Sporadic and familiar amyotrophic lateral sclerosis (ALS) cases presented lower cholinergic activity than in healthy individuals in their still preserved spinal motoneurons (MNs) suggesting that cholinergic reduction might occur before MN death. [...]
2013 - 10.1002/brb3.104
Brain and Behavior, Vol. 3, Núm. 2 (February 2013) , p. 145-158  
4.
17 p, 5.8 MB Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems / Herrando Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mulet, Roger (Anaxomics Biotech) ; Pujol, Albert (Institut de Recerca Biomèdica (Barcelona, Catalunya)) ; Mas, José Manuel (Anaxomics Biotech) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Aloy, Patrick (Institut de Recerca Biomèdica (Barcelona, Catalunya)) ; Coma, Mireia (Anaxomics Biotech) ; Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències)
Amyotrophic Lateral Sclerosis is a fatal, progressive neurodegenerative disease characterized by loss of motor neuron function for which there is no effective treatment. One of the main difficulties in developing new therapies lies on the multiple events that contribute to motor neuron death in amyotrophic lateral sclerosis. [...]
2016 - 10.1371/journal.pone.0147626
PLoS one, Vol. 11, Num. 1 (January 2016) , p. 1-17  
5.
34 p, 687.0 KB Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1G93A ALS mice and after partial muscle denervation / Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Leiva, Tatiana (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gregorio, David (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i Teràpia Gènica (CBATEG)) ; Ariza, Lorena (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i Teràpia Gènica (CBATEG)) ; Morell, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Esteban-Pérez, Jesús (Instituto de Investigación Biomédica Hospital 12 de Octubre (Madrid)) ; García-Redondo, Alberto (Instituto de Investigación Biomédica Hospital 12 de Octubre (Madrid)) ; Calvo, Ana C. (Kresge Hearing Research Institute (Michigan, Estats Units d'Amèrica)) ; Atencia-Cibreiro, Gabriela (Instituto de Investigación Biomédica Hospital 12 de Octubre (Madrid)) ; Corfas, Gabriel (Kresge Hearing Research Institute (Michigan, Estats Units d'Amèrica)) ; Osta, Rosario (Instituto Agroalimentario de Aragón (Saragossa)) ; Bosch i Merino, Assumpció (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of motoneurons, which is preceded by loss of neuromuscular connections in a "dying back" process. [...]
2016 - 10.1016/j.nbd.2016.07.023
Neurobiology of disease, Vol. 95 (November 2016) , p. 168-178  
6.
13 p, 2.2 MB CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves / Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Olmos Alonso, Adrian (University of Southampton. Centre for Biological Sciences) ; Osta, Rosario (Universidad de Zaragoza) ; Perry, V. Hugh (University of Southampton. Centre for Biological Sciences) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Gomez-Nicola, Diego (University of Southampton. Centre for Biological Sciences) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Inflammation is a common neuropathological feature in several neurological disorders, including amyotrophic lateral sclerosis (ALS). We have studied the contribution of CSF1R signalling to inflammation in ALS, as a pathway previously reported to control the expansion and activation of microglial cells. [...]
2016 - 10.1038/srep25663
Scientific Reports, Vol. 6 (May 2016) , article 25663  
7.
17 p, 38.6 MB Wnt signaling alteration in the spinal cord of Amyotrophic Lateral Sclerosis transgenic mice : special focus on Frizzled-5 cellular expression pattern / González-Fernández, Carlos (Hospital Nacional de Parapléjicos (Toledo)) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Del Valle i Macià, Jaume (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Rodríguez, Francisco Javier (Hospital Nacional de Parapléjicos (Toledo))
Background: Amyotrophic lateral sclerosis is a chronic neurodegenerative disease characterized by progressive paralysis due to degeneration of motor neurons by unknown causes. Recent evidence shows that Wnt signaling is involved in neurodegenerative processes, including Amyotrophic Lateral Sclerosis. [...]
2016 - 10.1371/journal.pone.0155867
PLoS One, Vol. 11, No 5 (May 2016) , p. e0155867  

Documents de recerca 1 registres trobats  
1.
198 p, 9.3 MB Electrophysiological biomarkers for the study of new therapeutic strategies for motoneuron disease / Mancuso, Renzo ; Navarro, X., (Xavier), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Introducción: La esclerosis lateral amiotrófica (ELA) es una enfermedad neurodegenerativa caracterizada por la aparición de debilidad progresiva que evoluciona en parálisis y finaliza con la muerte del paciente entre 3-5 años desde el diagnóstico. [...]
Introduction: Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease characterized by progressive weakness and paralysis, ending up with patient death 3-5 years after diagnosis. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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