Resultats globals: 12 registres trobats en 0.02 segons.
Articles, 12 registres trobats
Articles 12 registres trobats  1 - 10següent  anar al registre:
1.
11 p, 2.4 MB Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide / Martinez-Sanchez, Julia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Hamelmann, H. (Department of Hematology and Oncology. Berlin Institute of Health) ; Palomo, Marta (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mir, Enrique (Barcelona Endothelium Team. Josep Carreras Leukaemia Research Institute) ; Moreno-Castaño, A.B. (Department of Hematopathology. Biomedical Diagnosis Center (CDB). Institute of Biomedical Research August Pi i Sunyer (IDIBAPS). Hospital Clinic of Barcelona. University of Barcelona) ; Torramade, S. (Department of Hematopathology. Biomedical Diagnosis Center (CDB). Institute of Biomedical Research August Pi i Sunyer (IDIBAPS). Hospital Clinic of Barcelona. University of Barcelona) ; Rovira, M. (Stem Cell Transplantation Unit. IDIBAPS. Hospital Clinic. University of Barcelona) ; Escolar, G. (Department of Hematopathology. Biomedical Diagnosis Center (CDB). Institute of Biomedical Research August Pi i Sunyer (IDIBAPS). Hospital Clinic of Barcelona. University of Barcelona) ; Cordes, S. (Department of Hematology and Oncology. Berlin Institute of Health) ; Kalupa, M. (Department of Hematology and Oncology. Berlin Institute of Health) ; Mertlitz, S. (Department of Hematology and Oncology. Berlin Institute of Health) ; Riesner, K. (Department of Hematology and Oncology. Berlin Institute of Health) ; Carreras, E. (Barcelona Endothelium Team. Josep Carreras Leukaemia Research Institute) ; Penack, O. (Department of Hematology and Oncology. Berlin Institute of Health) ; Díaz-Ricart, Maribel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Angiogenesis and endothelial activation and dysfunction have been associated with acute graft-vs. -host disease (aGVHD), pointing to the endothelium as a potential target for pharmacological intervention. [...]
2019 - 10.3389/fimmu.2019.02339
Frontiers in immunology, Vol. 10 (september 2019) , p. 2339  
2.
29 p, 5.2 MB Sex-Dependent End-of-Life Mental and Vascular Scenarios for Compensatory Mechanisms in Mice with Normal and AD-Neurodegenerative Aging / Martori , Aida (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Puertas-Umbert, Lidia (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Jiménez-Xarrié, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Vila, Elisabet (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Giménez-Llort, Lydia (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Jiménez Altayó, Francesc (Universitat Autònoma de Barcelona. Institut de Neurociències)
Life expectancy decreases with aging, with cardiovascular, mental health, and neurodegenerative disorders strongly contributing to the total disability-adjusted life years. Interestingly, the morbidity/mortality paradox points to females having a worse healthy life expectancy. [...]
2021 - 10.3390/biomedicines9020111
Biomedicines, Vol. 9 Núm. 2 (2021) , p. 111  
3.
20 p, 5.1 MB Cardiovascular Risk Factors and Differential Transcriptomic Profile of the Subcutaneous and Visceral Adipose Tissue and Their Resident Stem Cells / Arderiu, Gemma (Institut d'Investigació Biomèdica Sant Pau) ; Ballesta, Carlos (Centro Médico Teknon. Barcelona) ; Moscatiello, Fabrizio (Centro Médico Teknon. Barcelona) ; Vilahur García-Lisón, Gemma (Institut d'Investigació Biomèdica Sant Pau) ; Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Lambert, Carmen (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Background: The increase in the incidence of obesity and obesity-related cardiovascular risk factors (CVRFs) over the last decades has brought attention on adipose tissue (AT) pathobiology. The expansion of AT is associated with the development of new vasculature needed to perfuse the tissue; however, not all fat depots have the same ability to induce angiogenesis that requires recruitment of their own endothelial cells. [...]
2020
Cells, Vol. 9 Núm. 10 (2020) , p. 2235  
4.
9 p, 325.6 KB Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1) : a phase III, international, randomized, placebo-controlled study / Van Cutsem, E (Division of Digestive Oncology, University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium) ; Yoshino, T (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan) ; Lenz, H J (Division of Medical Oncology, Norris Comprehensive Cancer Center, Los Angeles, USA) ; Lonardi, S (Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto - IRCCS, Padua) ; Falcone, A (Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy) ; Limón, M L (Department of Medical Oncology, Hospital Universitario Virgen del Rocio, Seville, Spain) ; Saunders, M (Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK) ; Sobrero, A (Department of Medical Oncology, Azienda Ospedaliera San Martino, Genoa, Italy) ; Park, Y S (Department of Hematology and Oncology, Samsung Medical Center, Seoul, South Korea) ; Ferreiro, R (Department of Clinical Oncology, Ramón y Cajal Hospital, Madrid, Spain) ; Hong, Y S (Department of Oncology, Asan Medical Center, Seoul, South Korea) ; Tomasek, J (Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ; Taniguchi, H (Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan) ; Ciardiello, F (Oncologia Medica, Seconda Università deli Studi di Napoli, Naples, Italy) ; Stoehr, J (Boehringer Ingelheim, Pharma GmbH & Co. KG, Biberach, Germany) ; Oum'Hamed, Z (Boehringer Ingelheim France S.A.S, Reims, France) ; Vlassak, S (SCS Boehringer Ingelheim Comm.V, Brussels, Belgium) ; Studeny, M (Division of Medicine/Clinical Development Department, Boehringer Ingelheim, Vienna, Austria) ; Argiles, G (VHIO Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Angiogenesis is critical to colorectal cancer (CRC) growth and metastasis. Phase I/II studies have demonstrated the efficacy of nintedanib, a triple angiokinase inhibitor, in patients with metastatic CRC. [...]
2018 - 10.1093/annonc/mdy241
Annals of oncology, Vol. 29 (july 2018) , p. 1955-1963  
5.
12 p, 1.3 MB Stem cells from human cardiac adipose tissue depots show different gene expression and functional capacities / Lambert, C. (Institut d'Investigació Biomèdica Sant Pau) ; Arderiu, G. (Institut d'Investigació Biomèdica Sant Pau) ; Bejar, M.T. (Institut d'Investigació Biomèdica Sant Pau) ; Crespo, J. (Institut d'Investigació Biomèdica Sant Pau) ; Baldellou, M. (Institut d'Investigació Biomèdica Sant Pau) ; Juan-Babot, O. (Institut d'Investigació Biomèdica Sant Pau) ; Badimon, L. (Cardiovascular Research Department UAB) ; Universitat Autònoma de Barcelona
Background: The composition and function of the adipose tissue covering the heart are poorly known. In this study, we have investigated the epicardial adipose tissue (EAT) covering the cardiac ventricular muscle and the EAT covering the left anterior descending artery (LAD) on the human heart, to identify their resident stem cell functional activity. [...]
2019 - 10.1186/s13287-019-1460-1
Stem cell research & therapy, Vol. 10 Núm. 1 (29 2019) , p. 361  
6.
9 p, 3.9 MB Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing / Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; Bragós, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Díaz-Güemes, Idoia (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Crisóstomo, Verónica (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Sánchez Margallo, Francisco M. (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Llucià Vallperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Bogónez Franco, Francisco Carlos (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. [...]
2017 - 10.5966/sctm.2016-0063
Stem cells translational medicine, Vol. 6 (2017) , p. 647-655  
7.
15 p, 3.4 MB Allogenic adipose-derived stem cell therapy overcomes ischemia-induced microvessel rarefaction in the myocardium : systems biology study / Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ; Oñate, Blanca (Institut d'Investigació Biomèdica Sant Pau) ; Cubedo, Judit (Institut d'Investigació Biomèdica Sant Pau) ; Béjar, Maria Teresa (Institut d'Investigació Biomèdica Sant Pau) ; Arderiu, Gemma (Institut d'Investigació Biomèdica Sant Pau) ; Peña, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Casaní, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Gutiérrez Capitán, Manuel (Institut d'Investigació Biomèdica Sant Pau) ; Capdevila, Antoni (Institut d'Investigació Biomèdica Sant Pau) ; Pons-Lladó, Guillem (Institut d'Investigació Biomèdica Sant Pau) ; Carreras, Francesc (Institut d'Investigació Biomèdica Sant Pau) ; Hidalgo, Alberto L (Institut d'Investigació Biomèdica Sant Pau) ; Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Myocardial microvascular loss after myocardial infarction (MI) remains a therapeutic challenge. Autologous stem cell therapy was considered as an alternative; however, it has shown modest benefits due to the impairing effects of cardiovascular risk factors on stem cells. [...]
2017 - 10.1186/s13287-017-0509-2
Stem cell research & therapy, Vol. 8 (march 2017)  
8.
9 p, 1.1 MB Biomarker analyses in REGARD gastric/GEJ carcinoma patients treated with VEGFR2-targeted antibody ramucirumab / Fuchs, Charles S (Dana-Farber Cancer Institute. Harvard Medical School) ; Taberneroo, J (Institut d'Oncologia de la Vall Hebron (VHIO)) ; Tomášek, Jiří (Masaryk University. Masaryk Memorial Cancer Institute (Czech Republic)) ; Chau, Ian (Royal Marsden Hospital (United Kingdom)) ; Melichar, Bohuslav (Univerzity Palackeho a Fakultni nemocnice. Onkologicka klinika (Czech Republic)) ; Safran, Howard (Brown University Oncology Research Group (USA)) ; Tehfe, Mustapha A (Centre Hospitalier de Montréal (Canada)) ; Filip, Dumitru (Spitalul Judetean de Urgenta (Romania)) ; Topuzov, Eldar (Northwest State Medical University na II Mechnikov. State Budgetary Educational Institution of Higher Professional Education (SBEIHPE). Ministry of Healthcare of the Russian Federation) ; Schlittler, Luis (Hospital da Cida de Passo Fundo (Brasil)) ; Udrea, Anghel Adrian (Medisprof SRL (Romania)) ; Campbell, William (Hospital Herrera Llerandi (Guatemala)) ; Brincat, Stephen (Sir Anthony Mamo Oncology Centre (Malta)) ; Emig, Michael (Lilly Deutschland GmbH (Germany)) ; Melemed, Symantha A (Eli Lilly and Company. Lilly Corporate Center (USA)) ; Hozak, Rebecca R (Eli Lilly and Company. Lilly Corporate Center (USA)) ; Ferry, David (Eli Lilly and Company (USA)) ; Caldwell, C William (Eli Lilly and Company. Lilly Corporate Center (USA)) ; Ajani, Jaffer A (The University of Texas MD Anderson Cancer Center (USA)) ; Universitat Autònoma de Barcelona
Angiogenesis inhibition is an important strategy for cancer treatment. Ramucirumab, a human IgG1 monoclonal antibody that targets VEGF receptor 2 (VEGFR2), inhibits VEGF-A, -C, -D binding and endothelial cell proliferation. [...]
2016 - 10.1038/bjc.2016.293
British Journal of Cancer, Vol. 115, Issue 8 (October 2016) , p. 974-982  
9.
21 p, 3.3 MB Single Intracoronary Injection of Encapsulated Antagomir-92a Promotes Angiogenesis and Prevents Adverse Infarct Remodeling / Bellera, Neus (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodriguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferret, Eulalia (I+D Pierre-Fabre Ibérica S.A) ; Asín, Miguel Angel (I+D Pierre-Fabre Ibérica S.A) ; Gonzalez-Alujas, MªTeresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pérez-Rodon, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteves, Marielle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fonseca, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Toran, Nuria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ; Pérez, Amadeo (I+D Pierre-Fabre Ibérica S.A) ; Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Small and large preclinical animal models have shown that antagomir-92a-based therapy reduces early postischemic loss of function, but its effect on postinfarction remodeling is not known. In addition, the reported remote miR-92a inhibition in noncardiac organs prevents the translation of nonvectorized miR-targeted therapy to the clinical setting. [...]
2014 - 10.1161/JAHA.114.000946
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 3 (september 2014)  
10.
11 p, 542.3 KB Cerebral ischaemia and matrix metalloproteinase-9 modulate the angiogenic function of early and late outgrowth endothelial progenitor cells / Morancho, Anna (Vall d'Hebron Institut de Recerca) ; Hernández-Guillamon, Mar (Vall d'Hebron Institut de Recerca) ; Boada, Cristina (Vall d'Hebron Institut de Recerca) ; Barceló, Verónica (Vall d'Hebron Institut de Recerca) ; Giralt, Dolors (Vall d'Hebron Institut de Recerca) ; Ortega, Laura (Vall d'Hebron Institut de Recerca) ; Montaner, Joan (Vall d'Hebron Institut de Recerca) ; Rosell, Anna (Vall d'Hebron Institut de Recerca) ; Universitat Autònoma de Barcelona
The enhancement of endogenous angiogenesis after stroke will be critical in neurorepair therapies where endothelial progenitor cells (EPCs) might be key players. Our aim was to determine the influence of cerebral ischaemia and the role of matrix metalloproteinase-9 (MMP-9) on the angiogenic function of EPCs. [...]
2013 - 10.1111/jcmm.12116
Journal of Cellular and Molecular Medicine, Vol. 17 (august 2013) , p. 1543-1553  

Articles : 12 registres trobats   1 - 10següent  anar al registre:
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