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Resultats globals: 10 registres trobats en 0.01 segons.
Articles, 9 registres trobats
Documents de recerca, 1 registres trobats
Articles 9 registres trobats  
1.
18 p, 2.9 MB Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection / Fuentes-Prior, Pablo (Institut d'Investigació Biomèdica Sant Pau)
The ongoing COVID-19 pandemic has already caused over a million deaths worldwide, and this death toll will be much higher before effective treatments and vaccines are available. The causative agent of the disease, the coronavirus SARS-CoV-2, shows important similarities with the previously emerged SARS-CoV-1, but also striking differences. [...]
2021 - 10.1074/jbc.REV120.015980
Journal of biological chemistry, Vol. 296 (january 2021) , p. 100135  
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2.
38 p, 310.7 KB The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome : analysis of high-throughput epigenetic and gene expression studies / Malato, João (Universidade de Lisboa) ; Sotzny, Franziska (Humboldt-Universität zu Berlin) ; Bauer, Sandra (Charité - Universitätsmedizin Berlin) ; Freitag, Helma (Charité - Universitätsmedizin Berlin) ; Fonseca, André (Universidade do Algarve) ; Grabowska, Anna D. (Medical University of Warsaw) ; Graça, Luís (Universidade de Lisboa) ; Cordeiro, Clara (Universidade do Algarve) ; Nacul, Luís (British Columbia Women's Hospital and Health Centre (Canada)) ; Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ; Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ; Westermeier, Francisco (Universidad Bernardo O'Higgins (Xile)) ; Sepúlveda, Nuno (London School of Hygiene & Tropical Medicine) ; Universitat Autònoma de Barcelona
Patients affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) show specific epigenetic and gene expression signatures of the disease. However, it is unknown whether these signatures include abnormal levels of the human angiotensin-converting enzymes, ACE and ACE2, the latter being the main receptor described for the host-cell invasion by SARS-CoV-2. [...]
2021 - 10.1101/2021.03.23.21254175
medRxiv, april 2021  
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3.
16 p, 4.1 MB Association of renin-angiotensin system blockers with COVID-19 diagnosis and prognosis in patients with hypertension : a population-based study / Soler, María José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ribera, A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Méndez, Ana Belen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Andrés Villareal, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azancot, María A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Oristrell, Gerard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Méndez-Boo, Leonardo (Institut Català de la Salut) ; Cohen, Jordana (University of Pennsylvania) ; Barrabés, José A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferreira-Gonzalez, Ignacio (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Universitat Autònoma de Barcelona
The effect of renin-angiotensin system (RAS) blockade either by angiotensin-converting enzyme inhibitors (ACEis) or angiotensin-receptor blockers (ARBs) on coronavirus disease 2019 (COVID-19) susceptibility, mortality and severity is inadequately described. [...]
2021 - 10.1093/ckj/sfab161
Clinical Kidney Journal, Vol. 15 (september 2021) , p. 79-94  
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4.
12 p, 479.3 KB Effect of bariatric surgery on cardiac structure and function in obese patients : Role of the renin-angiotensin system / Oliveras, Anna (Hospital del Mar (Barcelona, Catalunya)) ; Molina, Lluís (Institut Hospital del Mar d'Investigacions Mèdiques) ; Goday Arnó, Albert (Universitat Autònoma de Barcelona. Departament de Medicina) ; Sans, Laia (Hospital del Mar (Barcelona, Catalunya)) ; Riera Oliva, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Vazquez, Susana (Hospital del Mar (Barcelona, Catalunya)) ; Benaiges, David (Institut Hospital del Mar d'Investigacions Mèdiques) ; Granados, Ana Marina (Dialysis Clinic of Burjassot) ; Ramon, José Manuel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pascual, Julio (Pascual Santos) (Hospital del Mar (Barcelona, Catalunya))
Echocardiographic alterations have been described in obesity, but their modifications after bariatric surgery (BS) and mechanisms are little known, mostly in normotensive patients. We aimed to analyze cardiac changes 1 year post-BS and to explore possible mechanisms. [...]
2020 - 10.1111/jch.14129
The Journal of Clinical Hypertension, Vol. 23 (december 2020) , p. 181-192  
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5.
9 p, 526.6 KB Small resistance artery disease and ACE2 in hypertension : A new paradigm in the context of COVID-19 / Galán, María (Institut d'Investigació Biomèdica Sant Pau) ; Jiménez-Altayó, F. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
Cardiovascular disease causes almost one third of deaths worldwide, and more than half are related to primary arterial hypertension (PAH). The occurrence of several deleterious events, such as hyperactivation of the renin-angiotensin system (RAS), and oxidative and inflammatory stress, contributes to the development of small vessel disease in PAH. [...]
2020 - 10.3389/fcvm.2020.588692
Frontiers in Cardiovascular Medicine, Vol. 7 (october 2020) , p. 588692  
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6.
33 p, 1.1 MB Electrochemically reduced graphene and iridium oxide nanoparticles for inhibition-based angiotensin-converting enzyme inhibitor detection / Kurbanoglu, Sevinc (Institut Català de Nanociència i Nanotecnologia) ; Rivas, Lourdes (Institut Català de Nanociència i Nanotecnologia) ; Ozkan, Sibel A. (Ankara University. Department of Analytical Chemistry) ; Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
In this work, a novel biosensor based on electrochemically reduced graphene oxide and iridium oxide nanoparticles for the detection of angiotensin-converting enzyme inhibitor drug, captopril, is presented. [...]
2017 - 10.1016/j.bios.2016.07.109
Biosensors & bioelectronics, Vol. 88 (February 2017) , p. 122-129  
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7.
8 p, 401.5 KB Impact of Medication Adherence on Mortality and Cardiovascular Morbidity : Protocol for a Population-Based Cohort Study / Giner-Soriano, Maria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Sotorra Figuerola, Gerard (Universitat Autònoma de Barcelona) ; Cortés, Jordi (Universitat Autònoma de Barcelona) ; Pera Pujadas, Helena (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Garcia-Sangenis, Ana (Universitat Autònoma de Barcelona) ; Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Cardiovascular disease (CVD) is a group of disorders of the heart and blood vessels, such as coronary heart disease (CHD), cerebrovascular disease, and peripheral artery disease. CVD is the leading threat to global health, whether measured by mortality, morbidity, or economic cost. [...]
2018 - 10.2196/resprot.8121
JMIR Research Protocols, Vol. 7, Issue 3 (March 2018) , art. e73  
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8.
7 p, 412.7 KB Long-term effectiveness of agalsidase alfa enzyme replacement in Fabry disease : A Fabry Outcome Survey analysis / Beck, Michael (University Medical Center, University of Mainz, Department of Paediatrics) ; Hughes, Derralynn A (Royal Free London NHS Foundation Trust, University College of London) ; Kampmann, Christoph (University Medical Center, University of Mainz, Department of Paediatrics) ; Larroque, Sylvain (Shire, Zug) ; Mehta, Atul (Royal Free London NHS Foundation Trust, University College of London) ; Pintos-Morellell, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ramaswami, Uma (Royal Free London NHS Foundation Trust, University College of London) ; West, Michael (Department of Medicine, Dalhousie University) ; Wijatyk, Anna (Shire) ; Giugliani, Roberto (Medical Genetics Service HCPA/Dep Genet UFRGS and INAGEMP, Porto Alegre) ; Universitat Autònoma de Barcelona
Outcomes from 5 years of treatment with agalsidase alfa enzyme replacement therapy (ERT) for Fabry disease in patients enrolled in the Fabry Outcome Survey (FOS) were compared with published findings for untreated patients with Fabry disease. [...]
2015 - 10.1016/j.ymgmr.2015.02.002
Molecular Genetics and Metabolism Reports, Vol. 3 (march 2015) , p. 21-27  
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9.
9 p, 926.7 KB Antioxidant and Angiotensin 1 Converting Enzyme Inhibitory Functions from Chicken Collagen Hydrolysates / Soladoye, Olugbenga P. ; Saldo Periago, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Peiro, Lluis ; Rovira, Arnau ; Mor-Mur i Francesch, Montserrat (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Chicken collagen was explored for its possible ACE inhibitory and antioxidant activities. Flavourzyme, Neutrase and Alcalase were employed for hydrolysis of chicken collagen at predetermined times with optimal conditions for corresponding enzymes. [...]
2015 - 10.4172/2155-9600.1000369
Nutrition and Food Sciences, Vol. 5, Num. 3 (2015)  
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Documents de recerca 1 registres trobats  
1.
158 p, 3.2 MB Caracterització de la nova línia nod.Ace2-/-: estudi de l'aparició de diabetis i la progressió de la nefropatia diabètica / Roca Ho, Heleia ; Pascual, Julio, (Pascual Santos) dir. ; Soler Romeo, MªJosé, dir. ; Riera Oliva, Marta, dir. ; Bosch i Merino, Assumpció ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
L'enzim convertidor d'angiotensina (ECA) promou la formació de l'angiotensina II (Ang-II). Contràriament, l'ECA2, una monocarboxipeptidasa que presenta un 40% d'homologia amb l'ECA, degrada l'Ang-II (accions vasoconstrictores) a angiotensina 1-7 (Ang-(1-7) (accions vasodilatadores). [...]
Angiotensin converting enzyme (ACE) promotes angiotensin II (Ang II) formation. Conversely, ACE2, a monocarboxipeptidase that shares 40% homology with ACE, degrades promotes angiotensin 1-7 (Ang- (1-7) (vasodilator actions) formation from Ang-II (vasoconstrictor actions). [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2015  
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