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Articles, 24 registres trobats
Documents de recerca, 6 registres trobats
Articles 24 registres trobats  1 - 10següentfinal  anar al registre:
1.
9 p, 1.5 MB Rabbit as an animal model for the study of biological grafts in pelvic floor dysfunctions / Peró, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Casaní, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Castells-Sala, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Pérez, Maria Luisa (Institut d'Investigació Biomèdica Sant Pau) ; Moga, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Juan-Babot, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Alserawan De Lamo, Leticia (Institut d'Investigació Biomèdica Sant Pau) ; López-Chicón, Patricia (Institut d'Investigació Biomèdica Sant Pau) ; Vilarrodona Serrat, Anna (Institut d'Investigació Biomèdica Sant Pau) ; Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Porta Roda, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
The aims of this study were to evaluate the feasibility of the New Zealand White (NZW) rabbit for studying implanted biomaterials in pelvic reconstructive surgery; and to compare the occurrence of graft-related complications of a commercial polypropylene (PP) mesh and new developed human dermal matrix implanted at vaginal and abdominal level. [...]
2021 - 10.1038/s41598-021-89698-z
Scientific reports (Nature Publishing Group), Vol. 11 (may 2021)  
2.
25 p, 350.0 KB Twenty-first-century climate change impacts on marine animal biomass and ecosystem structure across ocean basins / Bryndum-Buchholz, Andrea (Dalhousie University. Department of Biology) ; Tittensor, Derek P. (Dalhousie University. Department of Biology) ; Blanchard, Julia L. (University of Tasmania. Center for Marine Socioecology) ; Cheung, William W. L (University of British Columbia. Institute for the Oceans and Fisheries) ; Coll, Marta (Institut de Ciències del Mar) ; Galbraith, Eric (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ; Jennings, Simon (University of East Anglia. School of Environmental Sciences) ; Maury, Olivier (University of Cape Town. International Lab. ICEMASA) ; Lotze, Heike K. (Dalhousie University. Department of Biology)
Climate change effects on marine ecosystems include impacts on primary production, ocean temperature, species distributions, and abundance at local to global scales. These changes will significantly alter marine ecosystem structure and function with associated socio-economic impacts on ecosystem services, marine fisheries, and fishery-dependent societies. [...]
2019 - 10.1111/gcb.14512
Global change biology, Vol. 25, issue 2 (Feb. 2019) , p. 459-472
6 documents
3.
13 p, 915.4 KB Comparison of direct and indirect models of early induced acute lung injury / Chimenti, Laura (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Morales-Quinteros, Luis (Grup Quirónsalud (Barcelona, Catalunya)) ; Puig, Ferranda (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Camprubi-Rimblas, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Guillamat Prats, Raquel (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ; Gómez, Maria Nieves (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Tijero, Jessica (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Blanch, Lluís (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Matute-Bello, Gustavo (University of Washington School of Medicine. Centre for Lung Biology, Division of Pulmonary and Critical Care Medicine, Department of Medicine) ; Artigas, Antonio (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Universitat Autònoma de Barcelona
The animal experimental counterpart of human acute respiratory distress syndrome (ARDS) is acute lung injury (ALI). Most models of ALI involve reproducing the clinical risk factors associated with human ARDS, such as sepsis or acid aspiration; however, none of these models fully replicates human ARDS. [...]
2020 - 10.1186/s40635-020-00350-y
Intensive Care Medicine Experimental, Vol. 8 (december 2020)  
4.
48 p, 682.2 KB Preclinical research in glycogen storage diseases : a comprehensive review of current animal models / Almodóvar Payá, Aitana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Villarreal-Salazar, Mónica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; de Luna Salva, Noemí (Institut d'Investigació Biomèdica Sant Pau) ; Nogales, Gisela (Institut Germans Trias i Pujol) ; Real-Martínez, Alberto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Antoni Andreu (European Infrastructure for Translational Medicine) ; Martín, Miguel Angel (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Arenas, Joaquin (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Lucia, Alejandro (Universidad Europea. Facultad de Ciencias del Deporte) ; Vissing,John (University of Copenhagen. Department of Neurology) ; Krag, Thomas (University of Copenhagen. Department of Neurology) ; Pinós Figueras, Tomàs (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
GSD are a group of disorders characterized by a defect in gene expression of specific enzymes involved in glycogen breakdown or synthesis, commonly resulting in the accumulation of glycogen in various tissues (primarily the liver and skeletal muscle). [...]
2020 - 10.3390/ijms21249621
International journal of molecular sciences, Vol. 21 Núm. 24 (2020) , p. 9621  
5.
30 p, 861.2 KB Relevance of Porcine Stroke Models to Bridge the Gap from Pre-Clinical Findings to Clinical Implementation / Melià Sorolla, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; De Gregorio-Rocasolano, Nuria (Institut Germans Trias i Pujol) ; Rodríguez-Esparragoza, Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martí-Sistac, Octavi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Gasull Dalmau, Teresa (Institut Germans Trias i Pujol) ; Castaño, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
In the search of animal stroke models providing translational advantages for biomedical research, pigs are large mammals with interesting brain characteristics and wide social acceptance. Compared to rodents, pigs have human-like highly gyrencephalic brains. [...]
2020 - 10.3390/ijms21186568
International journal of molecular sciences, Vol. 21 Núm. 18 (2020) , p. 6568  
6.
14 p, 2.9 MB Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome / Gella, Alejandro (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Prada-Dacasa, Patricia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Carrascal Pérez, Montserrat (Institut d'Investigacions Biomèdiques de Barcelona) ; Urpi, Andrea (Universitat Autònoma de Barcelona. Institut de Neurociències) ; González-Torres, Melania (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Abian, Joaquin (Institut d'Investigacions Biomèdiques de Barcelona) ; Sanz, Elisenda (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Quintana, Albert (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. [...]
2020 - 10.3389/fcell.2020.00660
Frontiers in Cell and Developmental Biology, Vol. 8 (july 2020)  
7.
12 p, 648.0 KB From transformation to chronification of migraine : pathophysiological and clinical aspects / Torres-Ferrús, M. (Hospital Universitari Vall d'Hebron) ; Ursitti, F. (Bambino Gesù Children's Hospital) ; Alpuente-Ruiz, A. (Hospital Universitari Vall d'Hebron) ; Brunello, F. (University Hospital of Padua. Juvenile Headache Centre, Department of Woman's and Child's Health) ; Chiappino, D. (University of Rome. Department of Internal medicine, Sant'Andrea Hospital) ; de Vries, T. (Erasmus University Medical Center. Division of Vascular Medicine and Pharmacology, Department of Internal Medicine) ; Di Marco, S. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics) ; Ferlisi, S. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics) ; Guerritore, L. (University of Rome. Department of Internal medicine, Sant'Andrea Hospital) ; Gonzalez-Garcia, N. (Hospital Clínico San Carlos (Madrid)) ; Gonzalez-Martinez, A. (Instituto de Investigación Hospital Universitario de la Princesa) ; Khutorov, D. (Department of Clinical Neurology and Sleep Medicine, The Nikiforov Russian Center of Emergency and Radiation Medicine of EMERCOM of Russia) ; Kritsilis, M. (Grevena General Hospital) ; Kyrou, A. (Bern University Hospital) ; Makeeva, T. (Headache Unit, Department of Neurology, Medical center "New Medical Technologies", Voronezh, Russia) ; Minguez-Olaondo, A. (Hospital Quirónsalud Donostia) ; Pilati, L. (Policlinico Paolo Giaccone Hospital, University of Palermo. Department of Biomedicine Neuroscience and Advanced Diagnostics) ; Serrien, A. (University Hospitals Leuven (Bèlgica)) ; Tsurkalenko, O. (Dnipropetrovsk medical akademy MOH Ukraine. Department of Neurology and Neurosurgery) ; Van den Abbeele, D. (Ghent University Hospital. (Bèlgica)) ; van Hoogstraten, W. S. (Erasmus University Medical Centre. Department of Neuroscience) ; Lampl, C. (Headache Medical Center Linz, Ordensklinikum Linz Barmherzige Schwestern) ; Universitat Autònoma de Barcelona ; VHIR Vall d'Hebron Institut de Recerca
Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. [...]
2020 - 10.1186/s10194-020-01111-8
Journal of headache and pain, Vol. 21 (april 2020)  
8.
34 p, 4.2 MB Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals / Taglialegna, Agustina (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ; Navarro, Susanna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Garnett, James A. (Queen Mary University of London. School of Biological and Chemical Sciences) ; Matthews, Steve (Imperial College London. Department of Life Sciences) ; Penades, José R. (University of Glasgow. College of Medical, Veterinary and Life Sciences) ; Lasa, Iñigo (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología) ; Valle, Jaione (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agrobiotecnología)
Biofilms are communities of bacteria that grow encased in an extracellular matrix that often contains proteins. The spatial organization and the molecular interactions between matrix scaffold proteins remain in most cases largely unknown. [...]
2016 - 10.1371/journal.ppat.1005711
PLoS pathogens, Vol. 12, issue 6 (June 2016) , p. e1005711  
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31 p, 4.4 MB The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility / Gomez Hernández, Laura (Centro de Investigación del Cáncer) ; Felipe Medina, Natalia (Centro de Investigación del Cáncer) ; Bejarano Condezo, Yazmine (Centro de Investigación del Cáncer) ; Garcia Valiente, Rodrigo (Centro de Investigación del Cáncer) ; Ramos, Isabel (Centro de Investigación del Cáncer) ; Suja, José Ángel (Universidad Autónoma de Madrid. Unidad de Biologia Celular) ; Barbero, José Luis (Centro de Investigaciones Biológicas (Madrid)) ; Roig, Ignasi (Ignasi) (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sanchez Martin, Manuel. (Universidad de Salamanca. Departamento de Medicina) ; De Rooij, Dirk G. (Utrecht University. Departent of Biology) ; Llano, Elena (Universidad de Salamanca. Departamento de Fisiología y Farmacología) ; Martín Pendas, Alberto (Centro de Investigación del Cáncer)
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [...]
2019 - 10.1371/journal.pgen.1008316
PLoS Genetics, Vol. 15, issue 8 (August 2019) , e1008316  
10.
11 p, 4.2 MB Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis / Penas Pérez, Clara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Maloof, M.E. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Stathias, V. (University of Miami Miller School of Medicine. Center for Therapeutic Innovation. Department of Psychiatry and Behavioral Sciences) ; Long, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Tan, S.K. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences) ; Mier, J. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Fang, Y. (The Rockefeller University. Laboratory of Development Neurobiology) ; Valdes, C. (Florida International University. Computing and Information Sciences) ; Rodriguez-Blanco, J. (University of Miami Miller School of Medicine. Department of Surgery) ; Chiang, C.M. (University of Texas Southwestern Medical Center. Simmons Comprehensive Cancer Center. Department of Biochemistry and Department of Pharmacology) ; Robbins, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ; Liebl, D.J. (University of Miami Miller School of Medicine. Department of Surgery) ; Lee, J.K. (University of Miami Miller School of Medicine. Department of Neurosurgery. Miami Project to Cure Paralysis) ; Hatten, M.E. (The Rockefeller University. Laboratory of Development Neurobiology) ; Clarke, J. (University of Nebraska. Department of Statistics) ; Ayad, N.G. (University of Miami Miller School of Medicine. Department of Psychiatry and Behavioral Sciences. Center for Therapeutic Innovation. Sylvester Comprehensive Cancer Center. Miami Project to Cure Paralysis)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric brain tumor, medulloblastoma. [...]
2019 - 10.1038/s41467-019-10799-5
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3028  

Articles : 24 registres trobats   1 - 10següentfinal  anar al registre:
Documents de recerca 6 registres trobats  
1.
181 p, 8.2 MB Antioxidant nanoparticles for the treatment of Age-related Macular Degeneration : preclinical studies in the DKOrd8 mouse model / Badia Pérez, Anna ; Fontrodona Montals, Laura, dir. ; García Arumí, José, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
La Degeneració Macular Associada a la Edat (DMAE) és una malaltia ocular degenerativa d'aparició tardana que afecta la retina central i causa una pèrdua progressiva de visió. La DMAE és una malaltia multifactorial en la qual l'envelliment és un dels principals factor de risc i on l'estrés oxidatiu, l'autofàgia i el sistema immunitari tenen una important rellevància en la seva patogènesis. [...]
La Degeneración Macular Asociada a la Edad (DMAE) es una enfermedad ocular degenerativa de aparición tardía que afecta a la retina central y causa una pérdida progresiva de visión. La DMAE es una enfermedad multifactorial en la que el envejecimiento es uno de los principales factores de riesgo y en la que el estrés oxidativo, la autofagia y el sistema inmunitario tienen una importante relevancia en su patogénesis. [...]
Age-related Macular Degeneration (AMD) is a late-onset degenerative eye disease that affects the central retina and causes progressive vision impairment. AMD is a multifactorial disease, with advanced age being the main risk factor and oxidative stress, autophagy and the immune system playing an important role in its pathogenesis. [...]

2019  
2.
172 p, 5.0 MB Schizophrenia-like sensorimotor gating deficits in intact inbred and outbred rats : from behavior to brain mechanisms and back / Tapias Espinosa, Carles ; Fernández-Teruel, Alberto, dir.
L'esquizofrènia és una malaltia mental incapacitant que involucra diversos símptomes cognitius, com un filtratge sensoriomotor deteriorat. El filtratge sensoriomotor es pot mesurar mitjançant la inhibició prepols (IPP) de la resposta d'ensurt. [...]
La esquizofrenia es una enfermedad mental incapacitante que involucra varios síntomas cognitivos, como un filtraje sensoriomotor deteriorado. El filtraje sensoriomotor se puede medir mediante la inhibición prepulso (IPP) de la respuesta de sobresalto. [...]
Schizophrenia is a debilitating mental disorder that involves several cognitive symptoms, including sensorimotor gating impairments. Sensorimotor gating can be measured via prepulse inhibition (PPI) of the startle response, in which the magnitude of a startle stimulus is attenuated by the presence of a pre-stimulus of lower intensity. [...]

2020  
3.
1 p, 1.2 MB Animal models for gene therapy of glycogenosis / Ramos Muntada, Mireia ; Bosch i Tubert, Fàtima, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Genètica [833]  
4.
1 p, 573.3 KB Animal model for schizophrenia / Riquelme-Alacid, Gemma ; Bosch i Merino, Assumpció, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  
5.
1 p, 902.4 KB Animal models in multiple sclerosis / Martí Fernández, Iris ; Hidalgo Pareja, Juan, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  
6.
1 p, 122.6 KB Animal models and gene therapy for diabetic neuropathy / Gregorio Martínez, David ; Bosch i Merino, Assumpció, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Ciències Biomèdiques [832]  

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