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10 p, 810.2 KB |
Assessment of the Plans to Optimize Antimicrobial Use in the Pediatric Population in Catalan Hospitals : The VINCat Pediatric PROA SHARP Survey
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Guarch-Ibáñez, Borja (Hospital Universitari de Girona Doctor Josep Trueta) ;
Fernández-Polo, Aurora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández Baeza, Sergi (Servei Català de la Salut) ;
Velasco-Arnaiz, Eneritz (Hospital Sant Joan de Déu (Manresa)) ;
Giménez, Montse (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sala-Castellvi, Pere (Hospital Universitari General de Catalunya) ;
Pineda, Valentí (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Melendo, Susana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
In Spain, many programs have been introduced in recent years to optimize antimicrobial stewardship in pediatric care (known as pediatric PROA). However, information on the current situation of these programs is scarce. [...]
2023 -  10.3390/antibiotics12020250
Antibiotics, Vol. 12 (january 2023)
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10 p, 390.5 KB |
The efficacy and tolerability of tetracyclines and clindamycin plus rifampicin for the treatment of hidradenitis suppurativa : Results of a prospective European cohort study
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van Straalen, Kelsey R. (Erasmus MC. University Medical Center Rotterdam. Department of Dermatology) ;
Tzellos, Thrasyvoulos (Department of Dermatology. Nordland Hospital Trust) ;
Guillem, Phillipe (Groupe de Recherche en Proctologie de la Société Nationale Française de ColoProctologie) ;
Benhadou, Farida (Department of Dermatology. Université Libre de Bruxelles. Erasme Hospital) ;
Cuenca-Barrales, Carlos (TECe19-Clinical and Translational Dermatology Investigation Group Instituto de Investigación Biosanitaria) ;
Daxhelet, Mathilde (Department of Dermatology. Université Libre de Bruxelles. Erasme Hospital) ;
Daoud, Mathieu (Department of Dermatology. Université Libre de Bruxelles. Erasme Hospital) ;
Efthymiou, Ourania (Second Department of Dermatology and Venereology. National and Kapodistrian University of Athens. Medical School. "Attikon" General University Hospital) ;
Giamarellos-Bourboulis, Evangelos J. (Fourth Department of Internal Medicine. National and Kapodistrian University of Athens. Medical School) ;
Jemec, Gregor B.E. (Department of Dermatology. Zealand University Hospital. Roskilde and Health Sciences Faculty. University of Copenhagen) ;
Katoulis, Alexandros C. (Second Department of Dermatology and Venereology. National and Kapodistrian University of Athens. Medical School. "Attikon" General University Hospital) ;
Koenig, Anke (Department of Dermatology. Venereology and Allergology. University Hospital Frankfurt am Main) ;
Lazaridou, Elizabeth (Second Department of Dermatology and Venereology. Aristotle University of Thessaloniki. General Hospital Papageorgiou) ;
Marzano, Angelo V. (Department of Pathophysiology and Transplantation. Università degli Studi di Milano) ;
Matusiak, Łucas (Department of Dermatology. Venereology and Allergology. Medical University) ;
Molina-Leyva, Alejandro (TECe19-Clinical and Translational Dermatology Investigation Group Instituto de Investigación Biosanitaria) ;
Moltrasio, Chiara (Department of Medical Surgical and Health Sciences. University of Trieste) ;
Pinter, Andreas (Department of Dermatology. Venereology and Allergology. University Hospital Frankfurt am Main) ;
Potenza, Concetta (Dermatology Unit 'Daniele Innocenzi. ' Department of Medical-Surgical Sciences and Biotechnologies. Sapienza University of Rome) ;
Romaní, Jorge (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Saunte, Ditte M. (Department of Dermatology. Zealand University Hospital. Roskilde and Health Sciences Faculty. University of Copenhagen) ;
Skroza, Nevena (Dermatology Unit 'Daniele Innocenzi. ' Department of Medical-Surgical Sciences and Biotechnologies. Sapienza University of Rome) ;
Stergianou, Dimitra (Fourth Department of Internal Medicine. National and Kapodistrian University of Athens. Medical School) ;
Szepietowski, Jacek (Department of Dermatology. Venereology and Allergology. Medical University) ;
Trigoni, Anastasia (Second Department of Dermatology and Venereology. Aristotle University of Thessaloniki. General Hospital Papageorgiou) ;
Vilarrasa-Rull, Eva (Institut d'Investigació Biomèdica Sant Pau) ;
van der Zee, Hessel H. (Erasmus MC. University Medical Center Rotterdam. Department of Dermatology) ;
Universitat Autònoma de Barcelona
Background: Tetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line therapy in current hidradenitis suppurativa guidelines. However, evidence for their efficacy is drawn from small studies, often without validated outcomes. [...]
2021 - 10.1016/j.jaad.2020.12.089
Journal of the American Academy of Dermatology, Vol. 85 Núm. 2 (august 2021) , p. 369-378
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8 p, 4.2 MB |
A Sensor Array Based on Molecularly Imprinted Polymers and Machine Learning for the Analysis of Fluoroquinolone Antibiotics
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Wang, Mingyue (Universitat Autònoma de Barcelona. Departament de Química) ;
Cetó Alsedà, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ;
Valle Zafra, Manuel del (Universitat Autònoma de Barcelona. Departament de Química)
Fluoroquinolones (FQs) are one of the most important types of antibiotics in the clinical, poultry, and aquaculture industries, and their monitoring is required as the abuse has led to severe issues, such as antibiotic residues and antimicrobial resistance. [...]
2022 - 10.1021/acssensors.2c01260
ACS Sensors, Vol. 7, Issue 11 (October 2022) , p. 3318-3325
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10 p, 696.8 KB |
Pharmacokinetics and Pharmacodynamics of Meropenem by Extended or Continuous Infusion in Low Body Weight Critically Ill Patients
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Luque, Sonia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Benítez-Cano, Adela (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Larrañaga, Leire (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Sorlí, Luisa (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Navarrete-Rouco, Maria Eugenia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Campillo, Núria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Carazo, Jesús (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ramos, Isabel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Adalia, Ramón (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Grau, Santiago (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Background : Pathophysiological changes such as extreme body weights in critically ill patients with severe infections may alter the pharmacokinetics (PK) of antimicrobials, leading to treatment failure or toxicity. [...]
2021 - 10.3390/antibiotics10060666
Antibiotics, Vol. 10 (june 2021)
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14 p, 2.0 MB |
Safety and Efficacy of Devices Delivering Inhaled Antibiotics among Adults with Non-Cystic Fibrosis Bronchiectasis : A Systematic Review and a Network Meta-Analysis
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Tejada, Sofia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramírez-Estrada, Sergio (Clínica Corachán. Intensive Care Department) ;
Forero, Carlos G. (Universitat Internacional de Catalunya) ;
Gallego, Miguel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Soriano, Joan B.. (Universidad Autónoma de Madrid) ;
Cardinal-Fernández, Pablo A. (HM Group (Madrid)) ;
Ehrmann, Stephan (Université de Tours. Centre d'étude des Pathologies Respiratoires) ;
Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca)
It remains unknown whether the type of aerosol generating device is affecting efficacy and safety among non-cystic fibrosis bronchiectasis (NCFB) adults. The proposal of this network meta-analysis (NMA) is to evaluate effectiveness and safety of inhaled antibiotics administered via dry powder inhaler (DPI) and via nebulizers (SVN) among adult patients with NCFB. [...]
2022 - 10.3390/antibiotics11020275
Antibiotics, Vol. 11 Núm. 2 (february 2022)
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18 p, 1.1 MB |
Phytochemicals as antibiotic alternatives to promote growth and enhance host health
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Lillehoj, Hyun (US Department of Agriculture. Agricultural Research Service) ;
Liu, Yanhong (University of California) ;
Calsamiglia, Sergio (Universitat Autònoma de Barcelona. Servei de Nutrició i Benestar Animal) ;
Fernandez-Miyakawa, Mariano E. (Instituto Nacional de Tecnología Agropecuaria. Instituto de Patobiología) ;
Chi, Fang (Amlan International) ;
Cravens, Ron L. (Amlan International) ;
Oh, Sungtaek (US Department of Agriculture. Animal Biosciences and Biotechnology Laboratory) ;
Gay, Cyril G. (US Department of Agriculture. National Program Staff-Animal Health)
There are heightened concerns globally on emerging drug-resistant superbugs and the lack of new antibiotics for treating human and animal diseases. For the agricultural industry, there is an urgent need to develop strategies to replace antibiotics for food-producing animals, especially poultry and livestock. [...]
2018 - 10.1186/s13567-018-0562-6
Veterinary research, Vol. 49 (july 2018)
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10 p, 656.4 KB |
Improved empirical antibiotic treatment of sepsis after an educational intervention : the ABISS-Edusepsis study
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Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martínez, María Luisa (Universitat Autònoma de Barcelona) ;
Gomà, Gemma (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Suárez, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Álvarez-Rocha, Luis (Complejo Hospitalario Universitario de A Coruña) ;
de la Torre, María Victoria (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
González, Gumersindo (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Zaragoza, Rafael (Hospital Universitari Doctor Peset (València)) ;
Borges, Marcio (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Blanco, Jesús (Hospital Universitario Río Hortega (Valladolid)) ;
Herrejón, Eduardo Palencia (Hospital Universitario Infanta Leonor) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Early appropriate antibiotic treatment is essential in sepsis. We aimed to evaluate the impact of a multifaceted educational intervention to improve antibiotic treatment. We hypothesized that the intervention would hasten and improve the appropriateness of empirical antibiotic administration, favor de-escalation, and decrease mortality. [...]
2018 - 10.1186/s13054-018-2091-0
Critical Care, Vol. 22 (june 2018)
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13 p, 4.6 MB |
Exploration into the origins and mobilization of di-hydrofolate reductase genes and the emergence of clinical resistance to trimethoprim
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Sánchez-Osuna, Miquel (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Cortés Garmendia, M. Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Llagostera Casas, Montserrat (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Barbé García, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Erill, Ivan (University of Maryland. Department of Biological Sciences)
Trimethoprim is a synthetic antibacterial agent that targets folate biosynthesis by competitively binding to the di-hydrofolate reductase enzyme (DHFR). Trimethoprim is often administered synergistically with sulfonamide, another chemotherapeutic agent targeting the di-hydropteroate synthase (DHPS) enzyme in the same pathway. [...]
2020 - 10.1099/mgen.0.000440
Microbial Genomics, Vol. 6, Issue 11 (September 2020) , art. 440
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16 p, 2.4 MB |
Breeding farm, level of feeding and presence of antibiotics in the feed influence rabbit cecal microbiota
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Velasco-Galilea, María (Institut de Recerca i Tecnologia Agroalimentàries) ;
Guivernau, Miriam (Institut de Recerca i Tecnologia Agroalimentàries) ;
Piles, Miriam (Institut de Recerca i Tecnologia Agroalimentàries) ;
Viñas, Marc (Institut de Recerca i Tecnologia Agroalimentàries) ;
Rafel Guarro, Oriol (Institut de Recerca i Tecnologia Agroalimentàries) ;
Sánchez Bonastre, Armando (Centre de Recerca en Agrigenòmica) ;
Ramayo-Caldas, Yuliaxis (Institut de Recerca i Tecnologia Agroalimentàries) ;
González-Rodríguez, Olga (Institut de Recerca i Tecnologia Agroalimentàries) ;
Sánchez, Juan P. (Institut de Recerca i Tecnologia Agroalimentàries) ;
Universitat Autònoma de Barcelona.
Departament de Ciència Animal i dels Aliments
The effect of the production environment and different management practices in rabbit cecal microbiota remains poorly understood. While previous studies have proved the impact of the age or the feed composition, research in the breeding farm and other animal management aspects, such as the presence of antibiotics in the feed or the level of feeding, is still needed. [...]
2020 - 10.1186/s42523-020-00059-z
Animal Microbiome, Vol. 2 (November 2020) , art. 40
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