Results overview: Found 5 records in 0.02 seconds.
Articles, 4 records found
Research literature, 1 records found
Articles 4 records found  
1.
5 p, 96.2 KB Incidence of depression in patients with hepatitis C treated with direct-acting antivirals / Egmond, Elfi (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ; Mariño, Zoe (Servei d'Hepatologia, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain) ; Navinés, Ricard (Universitat de Barcelona. Institut de Neurociències) ; Oriolo, Giovanni (Universitat de Barcelona. Institut de Neurociències) ; Pla, Anna (Servei d'Hepatologia, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain) ; Bartres, Concepció (Servei d'Hepatologia, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain) ; Lens, Sabela (Servei d'Hepatologia, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain) ; Forns, Xavier (Servei d'Hepatologia, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Universitat de Barcelona, Barcelona, Spain) ; Martin-Santos, Rocio (Instituto Nacional de Ciência e Tecnologia Translacional em Medicina (INCT-TM), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Ribeirão Preto, Brazil)
Depression has been associated with hepatitis C, as well as with its treatment with proinflammatory cytokines (i. e. , interferon). The new direct-acting antiviral agents (DAAs) have minimal adverse effects and high potency, with a direct inhibitory effect on non-structural viral proteins. [...]
2019 - 10.1590/1516-4446-2018-0336
Brazilian Journal of Psychiatry, Vol. 42 (july 2019) , p. 72-76  
2.
Whole-genome characterization and resistance-associated substitutions in a new HCV genotype 1 subtype / von Massow, G. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia, D. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd). Instituto de Salud Carlos III) ; Gregori, J. (Roche Diagnostics S.L) ; Rodriguez-Frias, F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Macià, M.D. (Unidad de Microbiología Molecular. Servicio de Microbiología. Instituto de Investigación Sanitaria de les Illes Balears (IdISBa). Hospital Universitario Son Espases) ; Escarda, A. (Digestive Department. Hospital Universitario Son Espases) ; Esteban, J.I. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Quer, J. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Universitat Autònoma de Barcelona. Departament de Medicina
Hepatitis C virus (HCV) is a highly variable infectious agent, classified into 8 genotypes and 86 subtypes. Our laboratory has implemented an in-house developed high-resolution HCV subtyping method based on next-generation sequencing (NGS) for error-free classification of the virus using phylogenetic analysis and analysis of genetic distances in sequences from patient samples compared to reference sequences. [...]
2019 - 10.2147/IDR.S195441
Infection and drug resistance, Vol. 12 (2019) , p. 947-955  
3.
17.3 KB Hepatitis C virus deep sequencing for sub-genotype identification in mixed infections : A real-life experience / del Campo, José A. (Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Hepáticas y Digestivas (CIBERehd) del Instituto de Salud Carlos III, Madrid, Spain) ; Parra-Sánchez, Manuel (UCM Infectious Diseases and Microbiology, Valme University Hospital, Seville, Spain) ; Figueruela, Blanca (UCM Digestive Diseases, Valme University Hospital, Seville, Spain) ; García-Rey, Silvia (UCM Infectious Diseases and Microbiology, Valme University Hospital, Seville, Spain) ; Quer Sivila, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gregori, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bernal, Samuel (UCM Infectious Diseases and Microbiology, Valme University Hospital, Seville, Spain) ; Grande, Lourdes (UCM Digestive Diseases, Valme University Hospital, Seville, Spain) ; Palomares, José C. (UCM Infectious Diseases and Microbiology, Valme University Hospital, Seville, Spain) ; Romero-Gómez, Manuel (Hospital Universitario Virgen del Rocío, Instituto de Investigación Biomédica de Sevilla (IBiS), Seville, Spain) ; Universitat Autònoma de Barcelona
The effectiveness of the new generation of hepatitis C treatments named direct-acting antiviral agents (DAAs) depends on the genotype, subtype, and resistance-associated substitutions present in individual patients. [...]
2018 - 10.1016/j.ijid.2017.12.016
International journal of infectious diseases, Vol. 67 (february 2018) , p. 114-117  
4.
7 p, 439.2 KB Management of direct antiviral agent failures / Buti, María (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Instituto de Salud Carlos III, Madrid) ; Esteban, Rafael (Esteban Mur) (Universitat Autònoma de Barcelona)
The current standard of care for patients with chronic hepatitis C virus (HCV) infection is a combination of direct-acting antiviral agents (DAAs). Most HCV patients treated with these drugs achieve viral elimination, but 1% to 15% fail to attain this objective. [...]
2016 - 10.3350/cmh.2016.0107
Clinical and Molecular Hepatology, Vol. 22 (december 2016) , p. 432-438  

Research literature 1 records found  
1.
123 p, 3.1 MB Caracterización molecular del perfil de resistencias del virus de la hepatitis C después del fallo terapéutico a antivirales de acción directa mediante secuenciación masiva / Chen, Qian ; Quer Sivila, Josep, dir. ; Perales Viejo, Celia, dir. ; Gregori i Font, Josep, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
La infección crónica por el virus de la hepatitis C constituye un problema de salud pública a nivel mundial por su contribución al desarrollo de enfermedades hepáticas avanzadas y carcinoma hepatocelular. [...]
Chronic hepatitis C infection is considered as a major public health issue worldwide due to its linkage to the development of advanced liver diseases and hepatocellular carcinoma. Currently, the availability of highly efficient and well-tolerated antiviral therapies based on combinations of direct acting antivirals (DAAs) has provided sustained virological response (SVR) in nearly 95% of patients. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  

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