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Articles, 37 registres trobats
Documents de recerca, 12 registres trobats
Articles 37 registres trobats  1 - 10següentfinal  anar al registre:
1.
13 p, 3.9 MB Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions / Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Calero-Nieto, F.J. (Department of Hematology. Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute. University of Cambridge) ; Wang, X. (Department of Hematology. Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute. University of Cambridge) ; Valdes-Mas, R. (Dreamgenics S.L. Oviedo) ; Gutiérrez-Agüera, Francisco (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Roca Ho, Heleia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ayllon, V. (GENyO. Centre for Genomics and Oncological Research. Pfizer/University of Granada/Andalusian Regional Government and University of Granada. Department of Biochemistry and Molecular Biology) ; Real, P.J. (GENyO. Centre for Genomics and Oncological Research. Pfizer/University of Granada/Andalusian Regional Government and University of Granada. Department of Biochemistry and Molecular Biology) ; Arambilet Mobilla, David (Institut Hospital del Mar d'Investigacions Mèdiques) ; Espinosa, Lluís (Institut Hospital del Mar d'Investigacions Mèdiques) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Varela, I. (Instituto de Biomedicina y Biotecnologia de Cantabria (CSIC-UC-Sodercan). Departamento de Biologia Molecular. Universidad de Cantabria) ; De Boer, J. (Cancer Section. UCL Great Ormond Street Institute of Child Health) ; Bigas, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ; Gottgens, B. (Department of Hematology. Cambridge Institute for Medical Research and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute. University of Cambridge) ; Marschalek, R. (Institute of Pharmaceutical Biology. Goethe-University) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
The t(4;11)(q21;q23) translocation is associated with high-risk infant pro-B-cell acute lymphoblastic leukemia and arises prenatally during embryonic/fetal hematopoiesis. The developmental/pathogenic contribution of the t(4;11)-resulting MLL-AF4 (MA4) and AF4-MLL (A4M) fusions remains unclear; MA4 is always expressed in patients with t(4;11)+ B-cell acute lymphoblastic leukemia, but the reciprocal fusion A4M is expressed in only half of the patients. [...]
2019 - 10.3324/haematol.2018.202044
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1189-1201  
2.
8 p, 1.4 MB Antitumoral effect of maintained neutrophilia induced by rhG-CSF in a murine model of pancreatic cancer / Brú, A. (Faculty of Mathematics. Universidad Complutense de Madrid) ; Bosch, R. (Institut d'Investigació Biomèdica Sant Pau) ; Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ; Carmona, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Pascual, E. (Institut d'Investigació Biomèdica Sant Pau) ; Brú, I. (Centro de Salud La Estación) ; Souto, J.C. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Although the protumoral functions of polymorphonuclear neutrophils are well known, some now-forgotten studies report antitumoral roles for these cells. The present work examines the antitumoral effect of maintained neutrophilia induced via the injection of recombinant human granulocyte colony stimulating factor (rhG-CSF, 100 μg/kg/day) in a Panc-1 subcutaneous xenograft murine model of pancreatic cancer. [...]
2019 - 10.1038/s41598-019-39805-y
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2879  
3.
22 p, 5.2 MB Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment / Urdinguio, R.G. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Lopez, V. (Nanomaterials and Nanotechnology Research Center (CINN-CSIC). Universidad de Oviedo-Principado de Asturias) ; Bayón, G.F. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Díaz de la Guardia, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sierra, M.I. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; García-Toraño, E. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Perez, R.F. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; García, M.G. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Carella, A. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Pruneda, P.C. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Prieto, C. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Dmitrijeva, M. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Santamarina, P. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Belmonte, T. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Mangas, C. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Diaconu, E. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Ferrero, C. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Tejedor, J.R. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Fernandez-Morera, J.L. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Bravo, C. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sanjuan-Pla, A. (Hematology Research Group. Instituto de Investigación Sanitaria la Fe (IIS la Fe)) ; Rodriguez, R.M. (Translational Immunology Laboratory. Instituto de Investigación Sanitarias Del Principado de Asturias (ISPA). Immunology Department. Hospital Universitario Central de Asturias (HUCA)) ; Suarez-Alvarez, B. (Translational Immunology Laboratory. Instituto de Investigación Sanitarias Del Principado de Asturias (ISPA). Immunology Department. Hospital Universitario Central de Asturias (HUCA)) ; López-Larrea, C. (Translational Immunology Laboratory. Instituto de Investigación Sanitarias Del Principado de Asturias (ISPA). Immunology Department. Hospital Universitario Central de Asturias (HUCA)) ; Bernal, T. (Servicio de Hematología. Hospital Universitario Central de Asturias (HUCA)) ; Colado, E. (Servicio de Hematología. Hospital Universitario Central de Asturias (HUCA)) ; Balbín, M. (Service of Molecular Oncology. Hospital Universitario Central de Asturias. Instituto Universitario de Oncología Del Principado de Asturias. Universidad de Oviedo) ; García-Suarez, O. (Department of Morphology and Cellular Biology. Faculty of Medicine. University of Oviedo) ; Chiara, M.D. (Otorhinolaryngology Service. Hospital Universitario Central de Asturias. Instituto Universitario de Oncología Del Principado de Asturias. Universidad de Oviedo. CIBERONC) ; Sáenz-De-Santa-María, I. (Otorhinolaryngology Service. Hospital Universitario Central de Asturias. Instituto Universitario de Oncología Del Principado de Asturias. Universidad de Oviedo. CIBERONC) ; Rodríguez, F. (Departamento de Bioquímica y Biología Molecular. Facultad de Medicina. Instituto Universitario de Oncología (IUOPA). Universidad de Oviedo) ; Pando-Sandoval, A. (Hospital Universitario Central de Asturias (HUCA). Instituto Nacional de Silicosis (INS). Área Del Pulmón. Facultad de Medicina. Universidad de Oviedo) ; Rodrigo, L. (Hospital Universitario Central de Asturias (HUCA). Gastroenterology Service. Facultad de Medicina. Universidad de Oviedo) ; Santos, L. (Fundación para la Investigación Biosanitaria de Asturias (FINBA). Instituto de Investigación Sanitaria Del Principado de Asturias (ISPA)) ; Salas, A. (Cytometry Service. Servicios Científico-Técnicos (SCTs). Universidad de Oviedo) ; Vallejo-Díaz, J. (Department of Immunology and Oncology. National Center for Biotechnology. CNB-CSIC) ; C Carrera, A. (Department of Immunology and Oncology. National Center for Biotechnology. CNB-CSIC) ; Rico, D. (Institute of Cellular Medicine. Newcastle University) ; Hernández-López, I. (Institute of Cellular Medicine. Newcastle University) ; Vayá, A. (Hemorheology and Haemostasis Unit. Service of Clinical Pathology. La Fe University Hospital) ; Ricart, J.M. (Dermatology Service. Quirón Clinic) ; Seto, E. (George Washington University Cancer Center. Department of Biochemistry and Molecular Medicine. George Washington University) ; Sima-Teruel, N. (Chromatin Biology Laboratory. Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL)) ; Vaquero, Alejandro (Chromatin Biology Laboratory. Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL)) ; Valledor, L. (Plant Physiology Lab. Department of Organisms and Systems Biology. Faculty of Biology. University of Oviedo) ; Cañal, M.J. (Plant Physiology Lab. Department of Organisms and Systems Biology. Faculty of Biology. University of Oviedo) ; Pisano, D. (Bioinformatics Unit. Structural Biology and Biocomputing Program. Spanish National Cancer Research Center (CNIO)) ; Graña-Castro, O. (Bioinformatics Unit. Structural Biology and Biocomputing Program. Spanish National Cancer Research Center (CNIO)) ; Thomas, T. (Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology. University of Melbourne) ; Voss, A.K. (Walter and Eliza Hall Institute of Medical Research. Department of Medical Biology. University of Melbourne) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Villar-Garea, A. (R and D. Sanofi-Aventis Deutschland GmbH. Industriepark Höchst Building G878) ; Deutzmann, R. (Institute of Biochemistry. Genetics and Microbiology. University of Regensburg) ; Fernandez, A.F. (Cancer Epigenetics Laboratory. Institute of Oncology of Asturias (IUOPA). ISPA-Hospital Universitario Central de Asturias HUCA. Universidad de Oviedo) ; Fraga, M.F. (Nanomaterials and Nanotechnology Research Center (CINN-CSIC). Universidad de Oviedo-Principado de Asturias) ; Universitat Autònoma de Barcelona
Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly understood. [...]
2019 - 10.1093/nar/gkz195
Nucleic acids research, Vol. 47 Núm. 10 (april 2019) , p. 5016-5037  
4.
16 p, 1.4 MB A Shorter Equilibration Period Improves Post-Warming Outcomes after Vitrification and in Straw Dilution of In Vitro-Produced Bovine Embryos / Martínez-Rodero, Iris (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Ordóñez-León, Erika Alina (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Vendrell i Flotats, Meritxell (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Olegario Hidalgo, Carlos (Servei Regional de Recerca i Desenvolupament Agroalimentari d'Astúries. Departament de selecció i reproducció d'animals) ; Esmoris, Joseba (Aliança Basca de Recerca i Tecnologia (BRTA)) ; Mendibil, Xabier (Aliança Basca de Recerca i Tecnologia (BRTA)) ; Azcarate, Sabino (Aliança Basca de Recerca i Tecnologia (BRTA)) ; López Béjar, Manel (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ; Yeste Oliveras, Marc (Universitat de Girona. Departament de Biologia) ; Mogas Amorós, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; García-Martínez, Tania (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
This study was designed to the optimize vitrification and in-straw warming protocol of in vitro-produced bovine embryos by comparing two different equilibration periods, short equilibrium (SE: 3 min) and long equilibrium (LE: 12 min). [...]
2021 - 10.3390/biology10020142
Biology, Vol. 10 Núm. 2 (2021) , p. 142  
5.
20 p, 4.5 MB TSPAN1 : a Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance / Garcia Mayea, Yoelsis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mir, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carballo, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Temprana-Salvador, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lorente, Juan (Hospital Universitari Vall d'Hebron) ; Benavente, Sergi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Pedrero, Juana M. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; Allonca, Eva (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; Rodrigo, Juan P. (Centro de Investigación Biomédica en Red Cáncer (CIBERONC)) ; LLeonart, Matilde E. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Sensitization of resistant cells and cancer stem cells (CSCs) represents a major challenge in cancer therapy. A proteomic study revealed tetraspanin-1 (TSPAN1) as a protein involved in acquisition of cisplatin (CDDP) resistance (Data are available via ProteomeXchange with identifier PXD020159). [...]
2020 - 10.3390/cancers12113269
Cancers, Vol. 12 Núm. 11 (2020) , p. 3269  
6.
8 p, 1.1 MB Dying two deaths - programmed cell death regulation in development and disease / Huysmans, Marlies (Ghent University. Department of Plant Biotechnology and Bioinformatics) ; Lema A, Saul (Centre de Recerca en Agrigenòmica) ; Sánchez Coll, Núria (Centre de Recerca en Agrigenòmica) ; Nowack, Moritz K. (Ghent University. Department of Plant Biotechnology and Bioinformatics)
Programmed cell death (PCD) is a fundamental cellular process that has adopted a plethora of vital functions in multicellular organisms. In plants, PCD processes are elicited as an inherent part of regular development in specific cell types or tissues, but can also be triggered by biotic and abiotic stresses. [...]
2017 - 10.1016/j.pbi.2016.11.005
Current opinion in plant biology, Vol. 35 (February 2017) , p. 37-44  
7.
24 p, 25.7 MB p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes / Marcet-Ortega, Marina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pacheco, Sarai (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Martínez Marchal, Ana (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Castillo, Helena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Flores, Elsa (The University of Texas M. D. Anderson Cancer Center) ; Jasin, Maria (Memorial Sloan Kettering Cancer Center) ; Keeney, Scott (Memorial Sloan Kettering Cancer Center) ; Roig, I. (Ignasi) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
To protect germ cells from genomic instability, surveillance mechanisms ensure meiosis occurs properly. In mammals, spermatocytes that display recombination defects experience a so-called recombination-dependent arrest at the pachytene stage, which relies on the MRE11 complex-ATM-CHK2 pathway responding to unrepaired DNA double-strand breaks (DSBs). [...]
2017 - 10.1371/journal.pgen.1006845
PLoS Genetics, Vol. 13, issue 6 (2017) , art. e1006845  
8.
19 p, 1001.5 KB The ATM signaling network in development and disease / Stracker, Travis H. (Institut de Recerca Biomèdica) ; Roig, I. (Ignasi) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Knobel, Philip A. (Institut de Recerca Biomèdica) ; Marjanović, Marko (Institut de Recerca Biomèdica) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
The DNA damage response (DDR) rapidly recognizes DNA lesions and initiates the appropriate cellular programs to maintain genome integrity. This includes the coordination of cell cycle checkpoints, transcription, translation, DNA repair, metabolism, and cell fate decisions, such as apoptosis or senescence (Jackson and Bartek, 2009). [...]
2013 - 10.3389/fgene.2013.00037
Frontiers in genetics, Vol. 4 (March 2013) , art. 37  
9.
27 p, 21.8 MB The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes / Pacheco, Sarai (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Marcet-Ortega, Marina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lange, Julian (Memorial Sloan Kettering Cancer Center) ; Jasin, Maria (Memorial Sloan Kettering Cancer Center) ; Keeney, Scott (Memorial Sloan Kettering Cancer Center) ; Roig, I. (Ignasi) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Most mutations that compromise meiotic recombination or synapsis in mouse spermatocytes result in arrest and apoptosis at the pachytene stage of the first meiotic prophase. Two main mechanisms are thought to trigger arrest: one independent of the double-strand breaks (DSBs) that initiate meiotic recombination, and another activated by persistent recombination intermediates. [...]
2015 - 10.1371/journal.pgen.1005017
PLoS Genetics, Vol. 11, issue 3 (2015) , art. e1005017  
10.
31 p, 4.4 MB The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility / Gomez Hernández, Laura (Centro de Investigación del Cáncer) ; Felipe Medina, Natalia (Centro de Investigación del Cáncer) ; Bejarano Condezo, Yazmine (Centro de Investigación del Cáncer) ; Garcia Valiente, Rodrigo (Centro de Investigación del Cáncer) ; Ramos, Isabel (Centro de Investigación del Cáncer) ; Suja, José Ángel (Universidad Autónoma de Madrid. Unidad de Biologia Celular) ; Barbero, José Luis (Centro de Investigaciones Biológicas (Madrid)) ; Roig, I. (Ignasi) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sanchez Martin, Manuel. (Universidad de Salamanca. Departamento de Medicina) ; De Rooij, Dirk G. (Utrecht University. Departent of Biology) ; Llano, Elena (Departamento de Fisiologia y Farmacologia. Universidad de Salamanca) ; Martín Pendas, Alberto (Centro de Investigación del Cáncer)
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [...]
2019 - 10.1371/journal.pgen.1008316
PLoS Genetics, Vol. 15, issue 8 (August 2019) , e1008316  

Articles : 37 registres trobats   1 - 10següentfinal  anar al registre:
Documents de recerca 12 registres trobats  1 - 10següent  anar al registre:
1.
1 p, 2.6 MB Necroptosis, one type of regulated necrosis : classification of cellular death modalities and biomedical applications / Scheemaeker Cruset, Paula de ; Soriano Martín, Jorge, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Biotecnologia [815]  
2.
1 p, 629.1 KB PARways of death / Durán, Rodrigo ; Soriano Martín, Jorge, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
3.
1 p, 760.4 KB Polymorphisms in p53 and cancer therapy : how does the p53-R72P polymorphism affect the treatment outcome? / Navarro Barea, Natalia ; Armengol Rosell, Gemma, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
4.
226 p, 5.1 MB Efecte dels anticolinesteràsics huprina x i avcri104p3 en els processos neurodegeneratius i d'envelliment / Relat Pardo, Júlia ; Clos Guillén, Mª Victòria, dir. ; Pérez Fernández, Belén, dir. ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
Entre els diferents trastorns neurodegeneratius, la malaltia d'Alzheimer (MA) es caracteritza per la pèrdua progressiva de les funcions cognitives i l'alteració del comportament, essent el sistema colinèrgic central el principal sistema afectat. [...]
Among the different neurodegenerative disorders, Alzheimer's disease (AD) is characterized by the progressive loss of cognitive function and the altered behaviour, being the central cholinergic system the main affected. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
5.
126 p, 3.6 MB New insights into the MAPK function in meiotic progression and the regulation of osmostress-induced apoptosis in Xenopus oocytes / Yue, Jicheng ; López Blanco, José Manuel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
En el organismo modelo Xenopus laevis, los oocitos de estadio VI están parados indefinidamente en la profase (G2/M) de la meiosis I hasta que se produce una adecuada estimulación hormonal. Una red de regulación positiva alrededor de la cascada Mos/MEK/ERK asegura la maduración (GVBD) de los oocitos tras la estimulación con progesterona. [...]
In the model organism Xenopus laevis, oocytes at stage VI are standing in prophase (G2/M) of meiosis I indefinitely until proper hormone stimulation. A positive regulation network around the Mos/MEK/ERK cascade ensures the rapid maturation (GVBD) of the oocytes upon stimulation with progesterone. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
6.
153 p, 2.9 MB Characterization of the fas death receptor antagonist in the nervous system, lifeguard (LFG) / Urresti Ibáñez, Jorge ; Comella i Carnicé, Joan Xavier, 1963-, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
La activación del Receptor de Muerte Fas, también llamado APO-1 o CD95, da lugar a la formación del Death Inducing Signaling Complex (DISC). Este complejo proteico contiene FADD y caspasa-8, entre otras proteínas, y causa el corte y activación de caspasa-8, que finalmente da lugar a la apoptosis. [...]
Activation of the Death Receptor Fas, also called APO-1 or CD95, leads to the formation of the Death Inducing Signaling Complex (DISC). This protein complex comprises FADD and caspase-8, among other proteins, and it causes the cleavage and activation of caspase-8, that ultimately leads to apoptosis. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
7.
205 p, 4.9 MB Apoptosis-based immunotheraphy for thype 1 diabetes: from dendritic cells to antigen-specific liposomes / Pujol Autonell, Irma ; Vives Pi, Marta, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
La diabetis tipus 1 (DT1) és una malaltia metabòlica causada per la destrucció selectiva de les cèl·lules β pancreàtiques productores d'insulina per part del sistema immunitari. Actualment no hi ha cura ni prevenció per restaurar la secreció endògena d'insulina als pacients amb DT1. [...]
Type 1 diabetes (T1D) is a metabolic disease that results from the autoimmune attack against insulin-producing β-cells in the pancreatic islets of Langerhans. Currently, there is no treatment to restore endogenous insulin secretion in patients with T1D, so the development of new therapies to induce long-term tolerance has been an important medical health challenge. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
8.
171 p, 2.1 MB Mecanismos de regulación de la muerte del oocito por shock hiperosmótico / Ben Messaoud, Nabil ; López Blanco, José Manuel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Las proteínas quinasas p38 y JNK se activan por diversos tipos de estrés ambiental, tal como la radiación UV y el shock hiperosmótico, y regulan múltiples procesos biológicos, entre ellos la proliferación y la muerte celular. [...]
JNK and p38 stress protein kinases are activated by different stimuli like UV and hyperosmotic shock, and regulate multiple biological processes, from proliferation to cell death. Some properties of signalling systems, like ultrasensitivity, hysteresis, and all-or-none responses at a single cell level, are considered to be basic for understanding the regulation of irreversible processes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
9.
1 p, 1.1 MB Apoptosis : yeast as a model for the study of programmed cell death / Frau Amar, Sofía M. ; Fernández Gallegos, Ma. Rosario, (María Rosario), dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Biotecnologia [815]  
10.
1 p, 539.3 KB Further than apoptosis : cellular death and its relation with carcinogenic processes / Oliver, Xènia ; Terradas Ill, Mariona, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Biotecnologia [815]  

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