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15 p, 510.1 KB |
Clinical and Laboratory Features in Anti-NF155 Autoimmune Nodopathy
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Martín-Aguilar, Lorena (Institut d'Investigació Biomèdica Sant Pau) ;
Lleixà, Cinta (Institut d'Investigació Biomèdica Sant Pau) ;
Pascual-Goñi, Elba (Institut d'Investigació Biomèdica Sant Pau) ;
Caballero-Ávila, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Martinez-Martinez, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Rojas-Garcia, Ricard (Institut d'Investigació Biomèdica Sant Pau) ;
Cortés-Vicente, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Turon-Sans, Janina (Institut d'Investigació Biomèdica Sant Pau) ;
De Luna, Noemi (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Suarez-Calvet, Xavier (Institut d'Investigació Biomèdica Sant Pau) ;
Gallardo, Eduard (Institut d'Investigació Biomèdica Sant Pau) ;
Rajabally, Yusuf (Birmingham Women's and Children's Hospital (Regne Unit)) ;
Scotton, Sangeeta (Birmingham Women's and Children's Hospital (Regne Unit)) ;
Jacobs, Bart C. (Erasmus Medical Center) ;
Baars, Adája (Erasmus Medical Center) ;
Cortese, Andrea (Irccs Mondino Foundation) ;
Vegezzi, Elisa (Irccs Mondino Foundation) ;
Höftberger, Romana (Department of Neurology. Medical University of Vienna) ;
Zimprich, Fritz (Department of Neurology. Medical University of Vienna) ;
Roesler, Cornelia (Paracelsus Medical University) ;
Nobile-Orazio, Eduardo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Liberatore, Giuseppe (Irccs Humanitas Research Hospital. Milan University) ;
Hiew, Fu Liong (Kuala Lumpur General Hospital) ;
Martínez-Piñeiro, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Carvajal, Alejandra (Hospital Universitario Virgen de las Nieves (Granada)) ;
Piñar-Morales, Raquel (Hospital Universitario San Cecilio (Granada)) ;
Usón-Martín, Mercedes (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Albertí, Olalla (Hospital General San Jorge (Osca)) ;
López Pérez, María Ángeles (Hospital San Pedro de Alcántara) ;
Márquez, Fabian (Hospital Universitari de Girona Doctor Josep Trueta) ;
Pardo-Fernández, Julio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Muñoz-Delgado, Laura (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cabrera-Serrano, Macarena (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ortiz-Castellon, Nicolau (Hospital Universitari de Sant Joan de Reus (Tarragona)) ;
Bartolomé, Manuel (Complejo Asistencial de Ávila) ;
Duman, Özgür (Akdeniz University) ;
Bril, Vera (Toronto General Hospital. University Health Network. University of Toronto) ;
Segura-Chávez, Darwin (Instituto Nacional de Ciencias Neurológicas) ;
Pitarokoili, Kalliopi (St. Josef-Hospital. Ruhr-University Bochum) ;
Steen, Claudia (Sant Joseph Hospital) ;
Illa, Isabel (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Querol, Luis (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Background and ObjectivesTo study the clinical and laboratory features of antineurofascin-155 (NF155)-positive autoimmune nodopathy (AN). MethodsPatients with anti-NF155 antibodies detected on routine immunologic testing were included. [...]
2022 -  10.1212/NXI.0000000000001098
Neurology® neuroimmunology & neuroinflammation, Vol. 9 Núm. 1 (february 2022) , p. e1098
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8 p, 634.0 KB |
COVAD survey 2 long-term outcomes : unmet need and protocol
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Fazal, Zoha Zahid (Aga Khan University Hospital) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals) ;
Ravichandran, Naveen (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Lilleker, James B. (Manchester Centre for Clinical Neurosciences) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University. Department of Medical Ecology and Hydroclimatology) ;
Kim, Minchul (University of Illinois College of Medicine Peoria. Department of Internal Medicine) ;
Day, Jessica (University of Melbourne. Department of Medical Biology) ;
Makol, Ashima (Mayo Clinic. Division of Rheumatology) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin. Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology) ;
Gheita, Tamer (Cairo University. Rheumatology Department) ;
Salim, Babur (Rheumatology Department, Fauji Foundation Hospital (Pakistan)) ;
Velikova, Tsvetelina (Sofia University St. Kliment Ohridski. Department of Clinical Immunology) ;
Gracia-Ramos, Abraham Edgar (Department of Internal Medicine, General Hospital, National Medical Center, La Raza (Mèxic)) ;
Parodis, Ioannis (Örebro University. Department of Rheumatology) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds. Leeds Institute of Rheumatic and Musculoskeletal Medicine) ;
Chatterjee, Tulika (University of Illinois College of Medicine Peoria. Department of Internal Medicine, Center for Outcomes Research) ;
Cavagna, Lorenzo (Università degli studi di Pavia. Dipartimento di Medicine Interna e Terapia Medica) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza (Mèxic)) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Ziade, Nelly (Hotel-Dieu de France Hospital. Rheumatology Department) ;
Nune, Arvind (Southport and Ormskirk Hospital NHS Trust) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine. Department of Allergy and Rheumatology) ;
Gutiérrez, Carlos-Enrique Toro (Pontifica Javeriana University) ;
Caballero-Uribe, Carlo Vinicio (Department of Medicine, Hospital Universidad del Norte) ;
Dey, Dzifa (University of Ghana School of Medicine and Dentistry. Department of Medicine and Therapeutics) ;
Distler, Oliver (University of Zurich. Department of Rheumatology) ;
Chinoy, Hector (Salford Royal Hospital. Department of Rheumatology) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (City Hospital, Sandwell and West Birmingham Hospitals NHS Trust) ;
Universitat Autònoma de Barcelona
The online version contains supplementary material available at 10. 1007/s00296-022-05157-6.
2022 - 10.1007/s00296-022-05157-6
Rheumatology International, august 2022, p. 1-8
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10 p, 1.3 MB |
Coordinated local RNA overexpression of complement induced by interferon gamma in myositis
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Casal-Dominguez, Maria (Johns Hopkins University School of Medicine) ;
Pinal-Fernandez, Iago (Johns Hopkins University School of Medicine) ;
Pak, Katherine (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Muñoz-Braceras, Sandra (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Milisenda, Jose C. (Hospital Clínic i Provincial de Barcelona) ;
Torres-Ruiz, Jiram (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ;
Dell'Orso, Stefania (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Naz, Faiza (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Gutierrez-Cruz, Gustavo (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Duque-Jaimez, Yaiza (Hospital Clínic i Provincial de Barcelona) ;
Matas-Garcia, Ana (Hospital Clínic i Provincial de Barcelona) ;
Valls-Roca, Laura (Hospital Clínic i Provincial de Barcelona) ;
Garrabou, Glòria (Hospital Clínic i Provincial de Barcelona) ;
Trallero-Araguas, Ernesto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Walitt, Brian (National Institute of Neurological Disorders and Stroke) ;
Christopher-Stine, Lisa (Johns Hopkins University School of Medicine) ;
Lloyd, Thomas E. (Johns Hopkins University School of Medicine) ;
Paik, Julie J. (Johns Hopkins University School of Medicine) ;
Albayda, Jemima (Johns Hopkins University School of Medicine) ;
Corse, Andrea (Johns Hopkins University School of Medicine) ;
Grau, Josep Maria (Hospital Clínic i Provincial de Barcelona) ;
Selva O'Callaghan, Albert (Universitat Autònoma de Barcelona) ;
Mammen, Andrew L. (Johns Hopkins University School of Medicine)
Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq) analyses of muscle biopsy specimens revealed that complement genes are locally overexpressed and correlate with markers of myositis disease activity, including the expression of interferon-gamma (IFN γ)-induced genes. [...]
2023 - 10.1038/s41598-023-28838-z
Scientific reports, Vol. 13 (february 2023)
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12 p, 1.9 MB |
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease
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Watt, Stephen (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Vasquez, Louella (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Walter, Klaudia (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Mann, Alice L. (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Kundu, Kousik (School of Clinical Medicine. University of Cambridge) ;
Chen, Lu (Sichuan University) ;
Sims, Ying (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Ecker, Simone (UCL Cancer Institute) ;
Burden, Frances (National Health Service Blood and Transplant) ;
Farrow, Samantha (National Health Service Blood and Transplant) ;
Farr, Ben (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Iotchkova, Valentina (University of Oxford) ;
Elding, Heather (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Mead, Daniel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Tardaguila, Manuel (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Ponstingl, Hannes (Human Genetics. Wellcome Sanger Institute. Genome Campus) ;
Richardson, David (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Datta, Avik (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Flicek, Paul (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Clarke, Laura (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Downes, Kate (National Health Service Blood and Transplant) ;
Pastinen, Tomi (Center for Pediatric Genomic Medicine. Children's Mercy) ;
Fraser, Peter (Florida State University) ;
Frontini, Mattia (University of Exeter Medical School) ;
Javierre, B. M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Spivakov, Mikhail (Imperial College Faculty of Medicine) ;
Soranzo, Nicole (University of Cambridge)
Neutrophils play fundamental roles in innate immune response, shape adaptive immunity, and are a potentially causal cell type underpinning genetic associations with immune system traits and diseases. [...]
2021 - 10.1038/s41467-021-22548-8
Nature communications, Vol. 12 Núm. 1 (january 2021) , p. 2298
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12 p, 661.0 KB |
COVID-19 severity and vaccine breakthrough infections in idiopathic inflammatory myopathies, other systemic autoimmune and inflammatory diseases, and healthy controls : a multicenter cross-sectional study from the COVID-19 Vaccination in Autoimmune Diseases (COVAD) survey
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Hoff, Leonardo Santos (Universidade Potiguar (Brasil)) ;
Ravichandran, Naveen (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Day, Jessica (University of Melbourne) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Junior, Jucier Gonçalves (Universidade de Sao Paulo) ;
Lilleker, James B. (Northern Care Alliance NHS Foundation Trust) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University) ;
Kim, Minchul (University of Illinois College of Medicine. Center for Outcomes Research, Department of Internal Medicine) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin) ;
Makol, Ashima (Mayo Clinic) ;
Gheita, Tamer (Cairo University) ;
Salim, Babur (Fauji Foundation Hospital) ;
Velikova, Tsvetelina (University Hospital "Lozenetz") ;
Gracia-Ramos, Abraham Edgar (General Hospital, National Medical Center, La Raza") ;
Parodis, Ioannis (Örebro University) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds) ;
Chatterjee, Tulika (University of Illinois College of Medicine) ;
Cavagna, Lorenzo (Università degli studi di Pavia) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza) ;
Ziade, Nelly (Hotel-Dieu de France Hospital) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine) ;
Nune, Arvind (Southport and Ormskirk Hospitals NHS Trust) ;
Distler, Oliver (University Hospital Zurich (Suïssa)) ;
Cansu, Döndü Üsküdar (Eskişehir Osmangazi University) ;
Traboco, Lisa (St Luke's Medical Center-Global City) ;
Wibowo, Suryo Angorro Kusumo (Universitas Indonesia) ;
Tehozol, Erick Adrian Zamora (Instituto Mexicano del Seguro Social Delegación Yucatán) ;
Serrano, Jorge Rojas (Instituto Nacional de Enfermedades Respiratorias) ;
La Torre, Ignacio García-De (Hospital General de Occidente and University of Guadalajara) ;
Wincup, Chris (University College London. Centre for Adolescent Rheumatology Versus Arthritis) ;
Pauling, John D. (North Bristol NHS Trust) ;
Chinoy, Hector (Salford Royal Hospital) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (City Hospital, Sandwell and West Birmingham Hospitals NHS Trust) ;
Universitat Autònoma de Barcelona
We aimed to compare the spectrum and severity of COVID-19 and vaccine breakthrough infections (BIs) among patients with IIMs, other systemic autoimmune and inflammatory diseases (SAIDs), and healthy controls (HCs). [...]
2022 - 10.1007/s00296-022-05229-7
Rheumatology International, october 2022, p. 1-12
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1 p, 90.3 KB |
Corrigendum : Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses
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Ten Brinke, Anja (University of Amsterdam, Netherlands) ;
Marek-Trzonkowska, Natalia (Medical University of Gdańsk, Poland) ;
Mansilla Lopez, Maria Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Turksma, Annelies W. (University of Amsterdam, Netherlands) ;
Piekarska, Karolina (University of Gdańsk, Poland) ;
Iwaszkiewicz-Grzes, Dorota (University of Gdańsk, Poland) ;
Passerini, Laura (IRCCS San Raffaele Scientific Institute, Milan, Italy) ;
Locafaro, Grazia (IRCCS San Raffaele Scientific Institute, Milan, Italy) ;
Puñet Ortiz, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
van Ham, S. Marieke (University of Amsterdam, Netherlands) ;
Hernandez-Fuentes, Maria P. (King's College London, United Kingdom) ;
Martínez-Cáceres, Eva M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gregori, Silvia (IRCCS San Raffaele Scientific Institute, Milan, Italy)
2018 - 10.3389/fimmu.2018.00343
Frontiers in immunology, Vol. 9 (february 2018)
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15 p, 1.9 MB |
Autoimmune Diseases Are Linked to Type IIb Autoimmune Chronic Spontaneous Urticaria
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Kolkhir, Pavel (Charité - Universitätsmedizin Berlin) ;
Altrichter, Sabine (Charité - Universitätsmedizin Berlin) ;
Asero, Riccardo (Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano) ;
Daschner, Alvaro (Instituto de Investigación Hospital Universitario de la Princesa) ;
Ferrer, Marta (Instituto de Investigación Sanitaria de Navarra) ;
Giménez-Arnau, Ana M 1961- (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Hawro, Tomasz (Charité - Universitätsmedizin Berlin) ;
Jakob, Thilo (Justus Liebig Universität Giessen) ;
Kinaciyan, Tamar (Medical University of Vienna) ;
Kromminga, Arno (Bioagilytix Europe GmbH, Hamburg) ;
Konstantinou, George (424 General Military Training Hospital, Thessaloniki) ;
Makris, Michael (University General Hospital Attikon (Haidari, Grècia)) ;
Metz, Martin (Charité - Universitätsmedizin Berlin) ;
Skov, Per Stahl (RefLab ApS, Copenhagen) ;
Staubach, Petra (University Medical Center Mainz) ;
Sussman, Gordon (University of Toronto) ;
Zhang, Ke (David Geffen School of Medicine at UCLA) ;
Maurer, Marcus (Charité - Universitätsmedizin Berlin)
Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk of comorbid autoimmune diseases. [...]
2021 - 10.4168/aair.2021.13.4.545
Allergy, Asthma & Immunology Research, Vol. 13 (february 2021) , p. 545-559
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10 p, 1.3 MB |
General information for patients and carers considering haematopoietic stem cell transplantation (HSCT) for severe autoimmune diseases (ADs) : A position statement from the EBMT Autoimmune Diseases Working Party (ADWP), the EBMT Nurses Group, the EBMT Patient, Family and Donor Committee and the Joint Accreditation Committee of ISCT and EBMT (JACIE)
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Jessop, Helen (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ;
Farge, Dominique (McGill University) ;
Saccardi, Riccardo (Careggi University Hospital (Florència, Itàlia)) ;
Alexander, Tobias (Charité - Universitätsmedizin Berlin) ;
Rovira Tarrats, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Sharrack, Basil (University of Sheffield) ;
Greco, Raffaella (San Raffaele Scientific Institute) ;
Wulffraat, Nico (Wilhelmina Kinderziekenhuis) ;
Moore, John (St Vincent's Hospital (Sydney)) ;
Kazmi, Majid (King's College Hospital NHS Foundation Trust) ;
Badoglio, Manuela (EBMT Paris study office) ;
Adams, Geert (EBMT Executive Office) ;
Verhoeven, Bregje (EBMT Executive Office) ;
Murray, John (Christie Hospital NHS Foundation Trust) ;
Snowden, John A (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ;
Universitat Autònoma de Barcelona
Over the last 20 years, haematopoietic stem cell transplantation (HSCT) has been used to treat patients with severe autoimmune and inflammatory diseases whose response to standard treatment options has been limited, resulting in a poor long-term prognosis in terms of survival or disability. [...]
2019 - 10.1038/s41409-019-0430-7
Bone marrow transplantation, Vol. 54 Núm. 7 (january 2019) , p. 933-942
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