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1.
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23 p, 5.8 MB |
Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats
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Serra, Maria Pina (University of Cagliari) ;
Sanna, Francesco (University of Cagliari) ;
Boi, Marianna (University of Cagliari) ;
Trucas, Marcello (University of Cagliari) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria Giuseppa (University of Cagliari) ;
Giorgi, Osvaldo (University of Cagliari) ;
Quartu, Marina (University of Cagliari)
In this article, we describe the effects of tail pinch (TP), a mild acute stressor, on the levels of brain-derived neurotrophic factor (BDNF) and its tyrosine kinase receptor B (trkB) proteins in the hippocampus (HC) of the outbred Roman High- (RHA) and Low-Avoidance (RLA) rats, one of the most validated genetic models for the study of fear/anxiety- and stress-related behaviors. [...]
2023 -  10.3390/ijms24119498
International journal of molecular sciences, Vol. 24 (may 2023)
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2.
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19 p, 3.9 MB |
Hydrogen Sulfide Interacting with Cannabinoid 2 Receptors during Sciatic Nerve Injury-Induced Neuropathic Pain
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Bai, Xue (Institut d'Investigació Biomèdica Sant Pau) ;
Batallé Melgarejo, Gerard (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Martel, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Pol, Olga (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Hydrogen sulfide (HS) donors make opioids more effective in inhibiting nociception during inflammatory and neuropathic pain. We examined whether the analgesic, anxiolytic and/or antidepressant actions of the cannabinoid 2 receptor (CB2R) agonist, JWH-133, might be improved by pretreatment with HS donors, DADS and GYY4137 in mice with sciatic nerve injury-provoked neuropathy (CCI). [...]
2023 - 10.3390/antiox12061179
Antioxidants, Vol. 12 (may 2023)
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3.
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23 p, 6.2 MB |
Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors
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Serra, Maria Pina (University of Cagliari) ;
Sanna, Francesco (University of Cagliari) ;
Boi, Marianna (University of Cagliari) ;
Poddighe, Laura (University of Cagliari) ;
Secci, Lorenzo (University of Cagliari) ;
Trucas, Marcello (University of Cagliari) ;
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria Giuseppa (University of Cagliari) ;
Giorgi, Osvaldo (University of Cagliari) ;
Quartu, Marina (University of Cagliari)
The present work was undertaken to investigate the effects of acute forced swimming (FS) on the levels of brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (trkB) proteins in: the ventral tegmental area (VTA); the nucleus accumbens (Acb) shell and core compartments; and the anterior cingulate (ACg), prelimbic (PL) and infralimbic (IL) territories of the prefrontal cortex of genetic models of vulnerability (RLA, Roman low-avoidance rats) and resistance (RHA, Roman high-avoidance rats) to stress-induced depression. [...]
2022 - 10.3390/ijms232314995
International journal of molecular sciences, Vol. 23 (november 2022)
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4.
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22 p, 869.5 KB |
Effectiveness, cost-utility and physiological underpinnings of the FIBROWALK multicomponent therapy in online and outdoor format in individuals with fibromyalgia : Study protocol of a randomized, controlled trial (On&Out study)
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Serrat, Mayte (Hospital Universitari Vall d'Hebron) ;
Ferrés Puigdevall, Sònia (Escoles Universitàries Gimbernat i Tomàs Cerdà) ;
Auer, William (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Almirall, Míriam (Hospital Universitari Vall d'Hebron) ;
Lluch, Enrique (University of Valencia. Department of Physiotherapy) ;
D'Amico, Francesco (London School of Economics and Political Science) ;
Maes, Michael (Chulalongkorn University. Department of Psychiatry) ;
Lorente Sánchez, Sonia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Navarrete Hidalgo, Jaime (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Montero-Marín, Jesús (Parc Sanitari Sant Joan de Déu. Psychological Research in Fibromyalgia and Chronic Pain (AGORA Research Group)) ;
Neblett, Randy (PRIDE Research Foundation) ;
Nijs, Jo (Pain in Motion International Research Group (Belgium)) ;
Borràs, Xavier (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Luciano, Juan V. (Parc Sanitari Sant Joan de Déu. Psychological Research in Fibromyalgia and Chronic Pain (AGORA Research Group)) ;
Feliu-Soler, Albert (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Introduction: The On&Out study is aimed at assessing the effectiveness, cost-utility and physiological underpinnings of the FIBROWALK multicomponent intervention conducted in two different settings: online (FIBRO-On) or outdoors (FIBRO-Out). [...]
2022 - 10.3389/fphys.2022.1046613
Frontiers in physiology, Vol. 13 (november 2022)
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5.
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36 p, 1.2 MB |
Feeding the Brain : Effect of Nutrients on Cognition, Synaptic Function, and AMPA Receptors
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Fadó, Rut (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Molins, Anna (Universitat Internacional de Catalunya. Departament de Ciències Bàsiques) ;
Rojas, Rocío (Universitat Internacional de Catalunya. Departament de Ciències Bàsiques) ;
Casals, Nuria (Universitat Internacional de Catalunya. Departament de Ciències Bàsiques) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
In recent decades, traditional eating habits have been replaced by a more globalized diet, rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary factors contribute to cognitive health impairment as well as increase the incidence of metabolic diseases such as obesity and diabetes. [...]
2022 - 10.3390/nu14194137
Nutrients, Vol. 14 (october 2022)
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6.
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10 p, 635.2 KB |
BDNF and Cortisol in the Diagnosis of Cocaine-Induced Depression
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Fonseca, Francina 1972- (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Mestre-Pinto, Joan Ignasi (Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida) ;
Rodríguez-Minguela, Rocío (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Papaseit, Esther (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Pérez-Mañá, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Langohr, Klaus (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Barbuti, Margherita (University Hospital of Pisa (Pisa, Itàlia)) ;
Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Torrens, Marta (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Major depressive disorder (MDD) and cocaine use disorder (CUD) are related with disability and high mortality rates. The assessment and treatment of psychiatric comorbidity is challenging due to its high prevalence and its clinical severity, mostly due to suicide rates and the presence of medical comorbidities. [...]
2022 - 10.3389/fpsyt.2022.836771
Frontiers in psychiatry, Vol. 13 (march 2022)
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7.
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14 p, 1.5 MB |
Hunger and satiety peptides : is there a pattern to classify patients with prader-willi syndrome?
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Bueno, Marta (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Boixadera Planas, Ester (Universitat Autònoma de Barcelona. Servei d'Estadística Aplicada) ;
Blanco Hinojo, Laura (Hospital del Mar (Barcelona, Catalunya)) ;
Esteba-Castillo, Susanna (Parc Hospitalari Martí i Julià) ;
Giménez-Palop, Olga (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Torrents-Rodas, David (Philipps-Universität Marburg) ;
Pujol Nuez, Jesús (Hospital del Mar (Barcelona, Catalunya)) ;
Corripio, Raquel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Deus Yela, Juan (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Caixàs i Pedragós, Assumpta (Universitat Autònoma de Barcelona. Departament de Medicina)
Hyperphagia is one of the main problems of patients with Prader-Willi syndrome (PWS) to cope with everyday life. The underlying mechanisms are not yet well understood. Gut-brain hormones are an interrelated network that may be at least partially involved. [...]
2021 - 10.3390/jcm10215170
Journal of clinical medicine, Vol. 10 Núm. 21 (11-1 2021) , p. 5170
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8.
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15 p, 2.4 MB |
Effect of BDNF Val66Met on hippocampal subfields volumes and compensatory interaction with APOE-ε4 in middle-age cognitively unimpaired individuals from the ALFA study
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Vilor-Tejedor, N. (Universitat Pompeu Fabra) ;
Operto, Gregory (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Evans, T. E. (Erasmus MC University Medical Center Rotterdam. Department of Clinical Genetics) ;
Falcon, Carles (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Crous-Bou, Marta (Institut Català d'Oncologia) ;
Minguillón, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cacciaglia, Raffaele (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Milà-Alomà, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Grau-Rivera, Oriol (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Suárez-Calvet, Marc (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Garrido-Martín, Diego (Centre de Regulació Genòmica) ;
Moran, S (Institut d'Investigació Biomèdica de Bellvitge) ;
Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Adams, Hieab (Erasmus MC University Medical Center Rotterdam. Department of Radiology) ;
Molinuevo, José Luis (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Guigó, R. (Universitat Pompeu Fabra) ;
Gispert, Juan Domingo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Background: Current evidence supports the involvement of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism, and the ε4 allele of APOE gene in hippocampal-dependent functions. Previous studies on the association of Val66Met with whole hippocampal volume included patients of a variety of disorders. [...]
2020 - 10.1007/s00429-020-02125-3
Brain Structure and Function, Vol. 225 Núm. 8 (january 2020) , p. 2331-2345
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9.
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14 p, 2.2 MB |
Continuous Theta-Burst Stimulation in Children With High-Functioning Autism Spectrum Disorder and Typically Developing Children
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Jannati, Ali (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Block, Gabrielle (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Ryan, Mary A. (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Kaye, Harper L. (Harvard Medical School) ;
Kayarian, Fae B. (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Bashir, Shahid (Neuroscience Center, King Fahad Specialist Hospital Dammam) ;
Oberman, Lindsay M. (Neuroplasticity and Autism Spectrum Disorder Program, Department of Psychiatry and Human Behavior, E. P. Bradley Hospital, Warren Alpert Medical School, Brown University) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Rotenberg, Alexander (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Universitat Autònoma de Barcelona
Objectives : A neurophysiologic biomarker for autism spectrum disorder (ASD) is highly desirable and can improve diagnosis, monitoring, and assessment of therapeutic response among children with ASD. [...]
2020 - 10.3389/fnint.2020.00013
Frontiers in Integrative Neuroscience, Vol. 14 (march 2020)
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10.
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16 p, 1.3 MB |
Test-retest reliability of the effects of continuous theta-burst stimulation
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Jannati, Ali (Berenson-Allen Center for Noninvasive Brain Stimulation. Division of Cognitive Neurology. Department of Neurology. Harvard Medical School) ;
Fried, P. J. (Berenson-Allen Center for Noninvasive Brain Stimulation. Division of Cognitive Neurology. Department of Neurology. Harvard Medical School) ;
Block, G. (School of Medicine. New York Medical College) ;
Oberman, L. M. (Department of Medical and Clinical Psychology. Uniformed Services University of Health Sciences) ;
Rotenberg, Alexander (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Objectives: The utility of continuous theta-burst stimulation (cTBS) as index of cortical plasticity is limited by inadequate characterization of its test-retest reliability. We thus evaluated the reliability of cTBS aftereffects, and explored the roles of age and common single-nucleotide polymorphisms in the brain-derived neurotrophic factor (BDNF) and apolipoprotein E (APOE) genes. [...]
2019 - 10.3389/fnins.2019.00447
Frontiers in Neuroscience, Vol. 13 Núm. MAY (2019) , p. 447
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