Resultats globals: 171 registres trobats en 0.02 segons.
Articles, 148 registres trobats
Llibres i col·leccions, 3 registres trobats
Documents de recerca, 18 registres trobats
Materials didàctics, 2 registres trobats
Articles 148 registres trobats  1 - 10següentfinal  anar al registre:
1.
16 p, 2.1 MB Brewpitopes : a pipeline to refine B-cell epitope predictions during public health emergencies / Farriol-Duran, Roc (Barcelona Supercomputing Center) ; López-Aladid, Ruben (Pneumology Department. Hospital Clínic) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Torres, Antoni (Hospital Clínic i Provincial de Barcelona) ; Fernández-Barat, Laia (Hospital Clínic i Provincial de Barcelona)
The application of B-cell epitope identification to develop therapeutic antibodies and vaccine candidates is well established. However, the validation of epitopes is time-consuming and resource-intensive. [...]
2023 - 10.3389/fimmu.2023.1278534
Frontiers in immunology, Vol. 14 (2023) , p. 1278534  
2.
26 p, 183.5 KB Natural Selection and the Nature of Statistical Explanations / Deulofeu Batllori, Roger (Universitat Autònoma de Barcelona. Departament de Filosofia)
Existe una interpretación filosófica aceptada de la selección natural en la teoría evolutiva: la selección natural, junto con la mutación, la migración y la deriva, se consideran fuerzas que impulsan la evolución de las poblaciones. [...]
There is a widespread philosophical interpretation of natural selection in evolutionary theory: natural selection, like mutation, migration, and drift are seen as forces that propel the evolution of populations. [...]

2023 - 10.22201/iifs.18704905e.2023.1465
Critica. Revista Hispanoamericana de Filosofia, Vol. 55 Núm. 165 (2023) , p. 27-52  
3.
11 p, 338.4 KB Early Macrophage Infiltration and Sustained Inflammation in Kidneys From Deceased Donors Are Associated With Long-Term Renal Function / Guillén-Gómez, E. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Dasilva, I. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Silva, Irene (Institut d'Investigació Biomèdica Sant Pau) ; Arce, Yolanda (Institut d'Investigació Biomèdica Sant Pau) ; Facundo, C. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Ars, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ; Breda, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Ortiz, A. (IIS-Fundación Jiménez Díaz/UAM. REDinREN) ; Guirado, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Ballarín, J.A. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Díaz Encarnación, Montserrat Mercedes (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Kidney transplants from living donors (LDs) have a better outcome than those from deceased donors (DDs). Different factors have been suggested to justify the different outcome. In this study, we analyzed the infiltration and phenotype of monocytes/macrophages and the expression of inflammatory and fibrotic markers in renal biopsy specimens from 94 kidney recipients (60 DDs and 34 LDs) at baseline and 4 months after transplantation. [...]
2017 - 10.1111/ajt.13998
American Journal of Transplantation, Vol. 17 Núm. 3 (january 2017) , p. 733-743  
4.
9 p, 1.8 MB Clinical Prognosis of Right-Sided Infective Endocarditis not Associated with Cardiac Devices or Intravenous Drug use : a Cohort Study and Meta-Analysis / Rigau, P.V. (Hospital Universitari de Girona Doctor Josep Trueta) ; Moral, S. (Hospital Universitari de Girona Doctor Josep Trueta) ; Bosch, D. (Hospital Universitari de Girona Doctor Josep Trueta) ; Morales, M. (Hospital Universitari de Girona Doctor Josep Trueta) ; Frigola, J.M. (Hospital Universitari de Girona Doctor Josep Trueta) ; Albert, X. (Hospital Universitari de Girona Doctor Josep Trueta) ; Robles, R. (Hospital Universitari de Girona Doctor Josep Trueta) ; Ballesteros, E. (Institut Català de la Salut) ; Roqué i Figuls, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Aboal, Jaime (Hospital Universitari de Girona Doctor Josep Trueta) ; Brugada, Ramon (Hospital Universitari de Girona Doctor Josep Trueta) ; Universitat Autònoma de Barcelona
Right-sided infective endocarditis (RSIE), classically associated with intravenous drug use or intracardiac devices, is considered a good-prognosis infective endocarditis (IE) form. However, predisposing factors and prognosis for "NODID" RSIE (NOt associated with cardiac Devices or Intravenous Drug use) remain unclear. [...]
2020 - 10.1038/s41598-020-64220-z
Scientific reports, Vol. 10 Núm. 1 (january 2020) , p. 7179  
5.
12 p, 1.2 MB Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis / Gao, Yixin (Xuzhou Medical University) ; Wang, Ting (Xuzhou Medical University) ; Yu, Xinghao (Xuzhou Medical University) ; Ferrari, Raffaele (Russell Square House) ; Hernandez, Dena G. (Queen Square) ; Nalls, Michael A. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ; Rohrer, Jonathan D. (Queen Square) ; Ramasamy, Adaikalavan (University of Oxford) ; Kwok, John B.J. (University of New South Wales) ; Dobson-Stone, Carol (University of New South Wales) ; Brooks, William S. (University of New South Wales) ; Schofield, Peter R. (Neuroscience Research Australia) ; Halliday, Glenda M. (Neuroscience Research Australia) ; Hodges, John R. (Neuroscience Research Australia) ; Piguet, Olivier (Neuroscience Research Australia) ; Bartley, Lauren (Neuroscience Research Australia) ; Thompson, Elizabeth (University of Adelaide) ; Haan, Eric (University of Adelaide) ; Hernández, Isabel (Institut Català de Neurociéncies Aplicades) ; Ruiz, Agustín (Institut Català de Neurociéncies Aplicades) ; Boada, Mercè (Institut Català de Neurociéncies Aplicades) ; Borroni, Barbara (University of Brescia) ; Padovani, Alessandro (University of Brescia) ; Cruchaga, Carlos (Washington University School of Medicine) ; Cairns, Nigel J. (Washington University) ; Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Binetti, Giuliano (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Ghidoni, Roberta (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Forloni, Gianluigi (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ; Albani, Diego (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ; Galimberti, Daniela (IRCCS Ospedale Maggiore Policlinico) ; Fenoglio, Chiara (IRCCS Ospedale Maggiore Policlinico) ; Serpente, Maria (IRCCS Ospedale Maggiore Policlinico) ; Scarpini, Elio (University of Milan) ; Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Waldö, Maria Landqvist (Lund University) ; Nilsson, Karin (Lund University) ; Nilsson, Christer (Lund University) ; Mackenzie, Ian R.A. (University of British Columbia) ; Hsiung, Ging-Yuek R. (University of British Columbia) ; Mann, David M. A. (Salford Royal Hospital) ; Grafman, Jordan (Northwestern University) ; Morris, Christopher M. (Newcastle University) ; Attems, Johannes (Newcastle University) ; Griffiths, Timothy D. (Newcastle University Medical School) ; McKeith, Ian G. (Newcastle University) ; Thomas, Alan J. (Newcastle University) ; Pietrini, Pietro (IMT School for Advanced Studies) ; Huey, Edward D. (Columbia University) ; Wassermann, Eric M. (National Insititutes of Health) ; Baborie, Atik (University of Alberta Edmonton) ; Jaros, Evelyn (Newcastle University) ; Tierney, Michael C. (National Insititutes of Health) ; Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Razquin, Cristina (Universidad de Navarra) ; Ortega-Cubero, Sara (Universidad de Navarra) ; Alonso, Elena (Universidad de Navarra) ; Perneczky, Robert (West London Mental Health Trust) ; Diehl-Schmid, Janine (Technische Universität München) ; Alexopoulos, Panagiotis (Technische Universität München) ; Kurz, Alexander (Technische Universität München) ; Rainero, Innocenzo (A.O. Città della Salute e della Scienza di Torino) ; Rubino, Elisa (A.O. Città della Salute e della Scienza di Torino) ; Pinessi, Lorenzo (A.O. Città della Salute e della Scienza di Torino) ; Rogaeva, Ekaterina (University of Toronto) ; St George Hyslop, Peter (University of Cambridge) ; Rossi, Giacomina (Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Tagliavini, Fabrizio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Giaccone, Giorgio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Rowe, James B. (Behavioural and Clinical Neuroscience Institute) ; Schlachetzki, Johannes C. M. (University of California San Diego) ; Uphill, James (University College London. Institute of Neurology) ; Collinge, John (University College London. Institute of Neurology) ; Mead, Simon (University College London. Institute of Neurology) ; Danek, Adrian (German Center for Neurodegenerative Diseases (DZNE)) ; Van Deerlin, Vivianna M. (University of Pennsylvania Perelman School of Medicine) ; Grossman, Murray (University of Pennsylvania Perelman School of Medicine) ; Trojanowski, John Q. (University of Pennsylvania Perelman School of Medicine) ; van der Zee, Julie (University of Antwerp) ; Cruts, Marc (University of Antwerp) ; Van Broeckhoven, Christine (University of Antwerp) ; Cappa, Stefano F. (Vita-Salute University and San Raffaele Scientific Institute) ; Leber, Isabelle (CNRS UMR 7225) ; Hannequin, Didier (Rouen University Hospital (França)) ; Golfier, Véronique (CH Saint Brieuc) ; Vercelletto, Martine (CHU Nantes) ; Brice, Alexis (AP-HP. Hôpital de la Salpêtrière) ; Nacmias, Benedetta (University of Florence) ; Sorbi, Sandro (University of Florence and IRCCS "Don Carlo Gnocchi" Firenze) ; Bagnoli, Silvia (University of Florence) ; Piaceri, Irene (University of Florence) ; Nielsen, Jørgen E. (Copenhagen University Hospital) ; Hjermind, Lena E. (University of Copenhagen) ; Riemenschneider, Matthias (Saarland University) ; Mayhaus, Manuel (Saarland University) ; Ibach, Bernd (University Regensburg) ; Gasparoni, Gilles (Saarland University) ; Pichler, Sabrina (Saarland University) ; Gu, Wei (University of Luxembourg) ; Rossor, Martin N. (Queen Square) ; Fox, Nick C. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ; Warren, Jason D. (Queen Square) ; Spillantini, Maria Grazia (University of Cambridge) ; Morris, Huw R. (Russell Square House) ; Rizzu, Patrizia (German Center for Neurodegenerative Diseases-Tübingen) ; Heutink, Peter (German Center for Neurodegenerative Diseases-Tübingen) ; Snowden, Julie S. (University of Manchester) ; Rollinson, Sara (University of Manchester) ; Richardson, Anna (University of Manchester) ; Gerhard, Alexander (The University of Manchester) ; Bruni, Amalia C. (ASPCZ) ; Maletta, Raffaele (ASPCZ) ; Frangipane, Francesca (ASPCZ) ; Cupidi, Chiara (ASPCZ) ; Bernardi, Livia (ASPCZ) ; Anfossi, Maria (ASPCZ) ; Gallo, Maura (ASPCZ) ; Conidi, Maria Elena (ASPCZ) ; Smirne, Nicoletta (ASPCZ) ; Rademakers, Rosa (Mayo Clinic Jacksonville) ; Baker, Matt (Mayo Clinic Jacksonville) ; Dickson, Dennis W. (Mayo Clinic Jacksonville) ; Graff-Radford, Neill R. (Mayo Clinic Jacksonville) ; Petersen, Ronald C. (Mayo Clinic Rochester) ; Knopman, David (Mayo Clinic Rochester) ; Josephs, Keith A. (Mayo Clinic Rochester) ; Boeve, Bradley (Mayo Clinic Rochester) ; Parisi, Joseph E. (Mayo Clinic Rochester) ; Seeley, William W. (University of California) ; Miller, Bruce L. (University of California) ; Karydas, Anna M. (University of California) ; Rosen, Howard (University of California) ; van Swieten, John C. (VU University Medical Centre) ; Dopper, Elise G. P. (Erasmus Medical Centre) ; Seelaar, Harro (Erasmus Medical Centre) ; Pijnenburg, Yolande A. L. (VU University Medical Centre) ; Scheltens, Philip (VU University Medical Centre) ; Logroscino, Giancarlo (University of Bari) ; Capozzo, Rosa (University of Bari) ; Novelli, Valeria (Fondazione Policlinico Universitario A. Gemelli) ; Puca, Annibale A. (University of Salerno) ; Franceschi, Massimo (IRCCS Multimedica) ; Postiglione, Alfredo (University of Naples Federico II) ; Milan, Graziella (Geriatric Center Frullone- ASL Napoli 1 Centro) ; Sorrentino, Paolo (Geriatric Center Frullone- ASL Napoli 1 Centro) ; Kristiansen, Mark (Institute of Child Health (ICH)) ; Chiang, Huei-Hsin (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Graff, Caroline (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Pasquier, Florence (Univ Lille) ; Rollin, Adeline (Univ Lille) ; Deramecourt, Vincent (Univ Lille) ; Lebouvier, Thibaud (Univ Lille) ; Kapogiannis, Dimitrios (National Institute on Aging (NIA/NIH)) ; Ferrucci, Luigi (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ; Pickering-Brown, S. (University of Manchester) ; Singleton, Andrew B. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ; Hardy, John (Russell Square House) ; Momeni, Parastoo (Texas Tech University Health Science Center) ; Zhao, Huashuo (Xuzhou Medical University) ; Zeng, Ping (Xuzhou Medical University) ; Universitat Autònoma de Barcelona
We employed Mendelian randomization (MR) to evaluate the causal relationship between leukocyte telomere length (LTL) and amyotrophic lateral sclerosis (ALS) with summary statistics from genome-wide association studies (n = ~ 38,000 for LTL and ~ 81,000 for ALS in the European population; n = ~ 23,000 for LTL and ~ 4,100 for ALS in the Asian population). [...]
2020 - 10.1038/s41598-020-68848-9
Scientific reports, Vol. 10 Núm. 1 (january 2020) , p. 12184  
6.
25 p, 6.3 MB Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals / Álvarez-González, Lucía (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Arias-Sardá, Cristina (University of Kent. School of Biosciences) ; Montes-Espuña, Laia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Marin Gual, Laia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Vara González, Covadonga (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lister, Nicholas C. (University of New South Wales. School of Biotechnology and Biomolecular Sciences) ; Cuartero, Yasmina (Centre de Regulació Genòmica) ; García, Francisca (Universitat Autònoma de Barcelona. Servei de Cultius Cel·lulars, Producció d'Anticossos i Citometria) ; Deakin, Janine (University of Canberra. Institute for Applied Ecology) ; Renfree, Marilyn B. (The University of Melbourne. School of Biosciences) ; Robinson, Terence J. (Stellenbosch University. Department of Botany and Zoology) ; Martí-Renom, Marc A. (Centre de Regulació Genòmica) ; Waters, Paul D. (University of New South Wales. School of Biotechnology and Biomolecular Sciences) ; Farré, Marta (University of Kent. School of Biosciences) ; Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Studying the similarities and differences in genomic interactions between species provides fertile grounds for determining the evolutionary dynamics underpinning genome function and speciation. Here, we describe the principles of 3D genome folding in vertebrates and show how lineage-specific patterns of genome reshuffling can result in different chromatin configurations. [...]
2022 - 10.1016/j.celrep.2022.111839
Cell reports, Vol. 41, Issue 12 (December 2022) , art. 111839  
7.
15 p, 2.7 MB Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology / Navarro, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández González, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Riera del Brio, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montpeyó Garcia-Moreno, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lopez-Royo, Tresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castillo-Sanchez, Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carnicer-Cáceres, Clara (Institució Catalana de Recerca i Estudis Avançats) ; Arranz-Amo, Jose Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castillo-Ribelles, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pradas-Gracia, Eddie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Casas, Josefina (Institut de Química Avançada de Catalunya) ; Vila Bover, Miquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martinez-Vicente, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Mutations in the GBA gene that encodes the lysosomal enzyme β-glucocerebrosidase (GCase) are a major genetic risk factor for Parkinson's disease (PD). In this study, we generated a set of differentiated and stable human dopaminergic cell lines that express the two most prevalent GBA mutations as well as GBA knockout cell lines as a in vitro disease modeling system to study the relationship between mutant GBA and the abnormal accumulation of α-synuclein. [...]
2022 - 10.1038/s41531-022-00397-6
NPJ Parkinson's disease, Vol. 8 (october 2022)  
8.
12 p, 3.1 MB Remission outcomes in severe eosinophilic asthma with mepolizumab therapy : Analysis of the REDES study / Pavord, Ian (University of Oxford) ; Gardiner, Frances (GSK House) ; Heaney, Liam G. (Queen's University Belfast) ; Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Price, Robert G. (Biostatistics, GSK) ; Pullan, Alison (Plus-Project Partnership Ltd) ; Oppenheimer, John (UMDNJ-Rutgers New Jersey Medical School) ; Brusselle, Guy (Universitair Ziekenhuis Gent) ; Nagase, Hiroyuki (Teikyo University School of Medicine) ; Chupp, Geoffrey (Yale Center for Asthma and Airways Disease (YCAAD)) ; Pizzichini, Emilio (Federal University of Santa Catarina) ; Bañas-Conejero, David (GSK) ; Howarth, Peter (GSK House) ; Universitat Autònoma de Barcelona
Clinical remission as a multicomponent treatment goal in severe asthma is being explored in clinical practice. This post hoc analysis used data from the REDES study to assess the proportion of patients with severe eosinophilic asthma achieving our multicomponent definitions of clinical remission after 1 year of mepolizumab treatment. [...]
2023 - 10.3389/fimmu.2023.1150162
Frontiers in immunology, Vol. 14 (april 2023)  
9.
7 p, 1000.2 KB Spontaneous reperfusion enhances succinate concentration in peripheral blood from stemi patients but its levels does not correlate with myocardial infarct size or area at risk / Consegal, Marta (Hospital Universitari Vall d'Hebron) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron) ; García del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ; Otaegui, Imanol (Hospital Universitari Vall d'Hebron) ; Rodriguez-Palomares, Jose F (Hospital Universitari Vall d'Hebron) ; Martí Balaguer, Gerard (Hospital Universitari Vall d'Hebron) ; Serra-Vidal, Bernat (Hospital Universitari Vall d'Hebron) ; Bellera Gotarda, Neus (Hospital Universitari Vall d'Hebron) ; Ojeda-Ramos, Manuel (Hospital Universitari Vall d'Hebron) ; Valente, Filipa (Hospital Universitari Vall d'Hebron) ; Carmona, Maria Ángeles (Hospital Universitari Vall d'Hebron) ; Miró-Casas, Elisabet (Hospital Universitari Vall d'Hebron) ; Sambola, Antonia (Hospital Universitari Vall d'Hebron) ; Lidón, Rosa María (Hospital Universitari Vall d'Hebron) ; Bañeras, Jordi (Hospital Universitari Vall d'Hebron) ; Barrabés, José A (Hospital Universitari Vall d'Hebron) ; Rodríguez, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Benito, Begoña (Hospital Universitari Vall d'Hebron) ; Ruiz Meana, Marisol (Hospital Universitari Vall d'Hebron) ; Inserte Igual, Javier (Hospital Universitari Vall d'Hebron) ; Ferreira-Gonzalez, Ignacio (Hospital Universitari Vall d'Hebron) ; Rodríguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Succinate is enhanced during initial reperfusion in blood from the coronary sinus in ST-segment elevation myocardial infarction (STEMI) patients and in pigs submitted to transient coronary occlusion. [...]
2023 - 10.1038/s41598-023-34196-7
Scientific reports, Vol. 13 (april 2023)  
10.
13 p, 3.4 MB TEMPRANILLO homologs in apple regulate flowering time in the woodland strawberry Fragaria vesca / Dejahang, Ata (National Institute of Genetic Engineering and Biotechnology. Department of Plant Biotechnology (Iran)) ; Maghsoudi, Naeimeh (University of Tabriz. Department of Horticultural Sciences) ; Mousavi, Amir (National Institute of Genetic Engineering and Biotechnology. Department of Plant Biotechnology (Iran)) ; Farsad-Akhtar, Nader (University of Tabriz. Department of Plant Biology) ; Matias-Hernandez, Luis (Centre de Recerca en Agrigenòmica) ; Pelaz, Soraya (Centre de Recerca en Agrigenòmica) ; Folta, Kevin (University of Florida. Horticultural Sciences Department) ; Mahna, Nasser (Centre de Recerca en Agrigenòmica)
The long juvenile period of fruit trees makes their breeding costly and time-consuming. Therefore, flowering time engineering and shortening the juvenile phase have become a breeding priority for the genetic improvement of fruit tree crops. [...]
2023 - 10.1038/s41598-023-29059-0
Scientific reports, Vol. 13 (February 2023) , art. 1968  

Articles : 148 registres trobats   1 - 10següentfinal  anar al registre:
Llibres i col·leccions 3 registres trobats  
1.
Study of the Nonelementary Singular Points and the Dynamics Near the Infinity in Predator-Prey Systems / Diz-Pita, Érika (Universidade de Santiago de Compostela) ; Llibre, Jaume (Universitat Autònoma de Barcelona) ; Otero-Espinar, M. Victoria (Universidade de Santiago de Compostela)
In this chapter, we present the results obtained in two predator-prey systems, paying special attention to the dynamics near the infinity and the nonelementary singular points. First, the desingularization technique known as blow-up technique allows one to study any type of singularities of analytic systems in dimension two even if they are not elementary. [...]
Cham : Springer, 2023 (Nonlinear Systems and Complexity ; 38) - 10.1007/978-3-031-42689-6_5
Computational and Mathematical Models in Biology, 2023, p. 103-128  
2.
23 p, 2.5 MB Stable-isotope techniques to investigate sources of plant water / Barbeta i Margarit, Adrià (Bordeaux Science Agro) ; Ogée, Jérôme (Bordeaux Science Agro) ; Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Stable isotopologues of water (mainly 1H216O, HD16O and 1H218O) have been used for decades as tracers of the Earth's water cycle. In this chapter, we briefly describe the theoretical background and state-of-the-art techniques of the use of water stable isotopes to investigate the sources of plant water. [...]
Cham, Switzerland: Springer, 2018 - 10.1007/978-3-319-93233-0_26
Advances in Plant Ecophysiology Techniques, 2018, p. 439-456  
3.
18 p, 126.5 KB Recent advances in Pichia pastoris as host for heterologous expression system for lipases : a review / Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
The production of heterologous lipases is one of the most promising strategies to increase the productivity of the bioprocesses and to reduce costs, with the final objective that more industrial lipase applications could be implemented. [...]
New York : Humana Press, 2018 (Methods in Molecular Biology; 1835) - 10.1007/978-1-4939-8672-9_11
Lipases and Phospholipases, 2018, p. 205-216  

Documents de recerca 18 registres trobats  1 - 10següent  anar al registre:
1.
4.1 MB Agential Teleosemantics / Rama Folco, Tiago ; Balari, Sergio, dir.
El camp de la filosofia de la biologia està duent a terme el seu objectiu d'avaluar i repensar la visió heretada del segle anterior --l'anomenada Síntesi Moderna. Diferents teories i àrees de recerca han emergit a les darreres dècades per tractar diferents fenòmens biològics que, en primera instància, no poden ser explicats en el marc de la Síntesi Moderna. [...]
El campo de la filosofía de la biología está llevando acabo su objetivo de evaluar y repensar la visión heredada del siglo anterior ---la denominada Síntesis Moderna. Diferentes teorías y áreas de investigación han emergido en las últimas décadas para dar cuenta de diferentes fenómenos biológicos que, en primera instancia, no pueden ser explicados en el marco de la Síntesis Moderna. [...]
The field of the philosophy of biology is flourishing in its aim to evaluate and rethink the view inherited from the previous century ---the Modern Synthesis. Different research areas and theories have come to the fore in the last decades in order to account for different biological phenomena that, in the first instance, fall beyond the explanatory scope of the Modern Synthesis. [...]

2022  
2.
198 p, 4.1 MB Metabolic engineering of Pichia pastoris for 3-hydroxypropionic acid production from glycerol / Fina Romero, Albert ; Albiol i Sala, Joan, dir. ; Ferrer Alegre, Pau, dir.
L'àcid 3-hidroxipropiònic (3-HP), un producte plataforma, ha estat identificat com un dels productes de valor afegit més prometedors per ser obtinguts a partir de biomassa pel Departament d'Energia dels Estats Units. [...]
El ácido 3-hidroxipropiónico (3-HP), un producto plataforma, ha sido identificado como uno de los productos de valor añadido más prometedores para ser obtenidos a partir de biomasa por el Departamento de Energía de los Estados Unidos. [...]
3-hydroxypropionic acid (3-HP), a platform chemical, has been identified as one of the top value-added products to be produced from biomass by the US Energy Department. Consequently, 3-HP bioproduction has gained remarkable attention in recent years. [...]

2022  
3.
142 p, 6.5 MB Structural basis studies of Ubiquitin/SUMO-related protease activity / Li, Ying ; Reverter Cendrós, David, dir.
Les modificacions de proteïnes post-traduccionals per ubiquitina i SUMO regulen moltes vies principals a la cèl·lula. Aquestes modificacions es poden revertir mitjançant enzims deubiquitinants com les proteases específiques de la ubiquitina (USP) o les deSUMOilasees com les proteases específiques de SUMO (SENP). [...]
Las modificaciones de proteínas postraduccionales por ubiquitina y SUMO regulan muchas vías importantes en la célula. Estas modificaciones se pueden revertir mediante enzimas deubiquitinantes como las proteasas específicas de ubiquitina (USP) o deSUMOylantes como las proteasas específicas de SUMO (SENP). [...]
Post-translational protein modifications by ubiquitin and SUMO regulate many major pathways in the cell. These modifications can be reversed by de-ubiquitinating enzymes such as ubiquitin-specific proteases (USPs) or deSUMOylaseas such as SUMO-specific proteases (SENPs). [...]

2022  
4.
286 p, 19.3 MB Characteristics and Applications of the Anti-infective Activity of Eosinophil Derived RNases / Li, Jiarui ; Boix i Borràs, Esther, dir. ; Fernández Millán, Pablo, dir. ; Prats Ejarque, Guillem, dir.
En els darrers anys, els pèptids de defensa derivats de l'hoste estan destacant com a candidats prometedors per esdevenir nous agents antimicrobians. En el nostre laboratori, hem estat treballant amb les RNases derivades dels grànuls de l'eosinòfil; la neurotoxina derivada de l'eosinòfil (EDN/RNasa 2) i la proteïna catiònica de l'eosinòfil (ECP/RNasa 3), unes proteïnes del sistema immune innat que han demostrat tenir una activitat antimicrobiana d'ampli espectre. [...]
En los últimos años, los péptidos de defensa derivades del huésped están destacando como candidatos prometedores para convertirse en nuevos agentes antimicrobianos. En nuestro laboratorio, hemos estado trabajando con las RNasas derivadas de los gránulos del eosinófilo; la neurotoxina derivada del eosinófilo (EDN/RNasa 2) y la proteína catiónica del eosinófilo (ECP/RNasa 3), unas proteínas del sistema inmune innato que han demostrado tener una actividad antimicrobiana de amplio espectro. [...]
In the last years, host-derived defense peptides (HDPs) are emerging as promising candidates for new antimicrobial agents. In our laboratory, we have been working with eosinophil granules derived RNases, eosinophil-derived neurotoxin (EDN/RNase 2) and eosinophil cationic protein (ECP/RNase 3), proteins from the innate immune system that have been proven to show broad antimicrobial activities. [...]

2022  
5.
MASALA : a novel regulator of cellular plasticity encoded by a lncRNA / Merino Valverde, Iñaki ; Abad Méndez, Maria, dir.
Després de la seqüenciació de genomes durant els '90 i 2000s es va assumir que al voltant d'un 99% del genoma no tenia funció, arribant fins i tot a considerar-se "ADN escombraries". Al llarg dels anys, aquesta i altres suposicions sobre el genoma han anat canviant. [...]
Después de la secuenciación de genomas durante los '90 y 2000s se asumió que alrededor de un 99% del genoma no tenía función, llegando incluso a considerase "ADN basura". A lo largo de los años, ésta y otras suposiciones sobre el genoma han ido cambiando. [...]
After the sequencing of the genomes of different model organisms during the 90's and 2000's it was assumed that 99% of the genome did not have a function and was even considered "junk DNA". Along these years, this, and other assumptions about the genome have been challenged. [...]

2022  
6.
214 p, 5.7 MB Towards the therapeutic use of nanoparticles in cancer : a cellular perspective / Aranda-Ramos, Antonio ; Nogués, C. (Carme), dir.
Durant les últimes 3 dècades, la nanotecnologia s'ha convertit en un camp en constant creixement, incloent la seva aplicació a la medicina, la qual coneixem com a nanomedicina. Tot i les prometedores aplicacions potencials de la nanomedicina, la seva traducció a alternatives terapèutiques i diagnòstiques efectives és encara molt baixa. [...]
For the past three decades, nanotechnology has been an ever-growing field, including its application to medicine, what is known as nanomedicine. Despite the promising potential applications of nanomedicine, translation to effective therapeutic and diagnostic alternatives is still very low. [...]

2021  
7.
32.8 MB High throughput stationary 13C-Metabolic Flux Analysis of 3-hydroxypropionic acid producing Pichia pastoris strains. Supplementary materials of Chapter 5 of the PhD Thesis of Albert Fina Romero / Fina Romero, Albert (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Supplementary files of Chapter 5 of the PhD Thesis of Albert Fina Romero. This chapter describes the fluxome of 3-hydroxypropionic acid producing Pichia pastoris recombinant strains. Glycerol was used as a sole carbon source. [...]
Universitat Autònoma de Barcelona, 2022 - 10.5565/ddd.uab.cat/264385
2 documents
8.
2 p, 816.6 KB Synthetic all the way : engineering a synthetic yeast genome / Bárcenas, Oriol ; Universitat Autònoma de Barcelona. Facultat de Biociències
Synthetic biology is a rapidly evolving field that aims to design new biological systems (creating a chassis) or improve those already present in nature.
2022
Grau en Biotecnologia [815]  
9.
236 p, 19.2 MB Parámetros clínico-biológicos predictivos de respuesta al tratamiento y de recaída post-discontinuación en pacientes con leucemia mieloide crónica / Estrada Barreras, Natalia ; Zamora, Lurdes, dir. ; Xicoy, Blanca, dir. ; Schwartz Navarro, Simó, dir.
La supervivència global dels pacients amb leucèmia mieloide crònica (LMC) ha millorat substancialment gràcies a l'aparició d'imatinib i, posteriorment, dels inhibidors de la tirosina cinasa de 2ª generació (ITCs-2G). [...]
La supervivencia global de los pacientes con leucemia mieloide crónica (LMC) ha mejorado sustancialmente gracias a la aparición de imatinib y, posteriormente, de los inhibidores de la tirosina quinasa de 2ª generación (ITQs-2G). [...]
Overall survival of chronic myeloid leukemia (CML) patients has improved significantly since the introduction of imatinib and, later, second generation tyrosine kinase inhibitors (2G-TKI). Imatinib is indicated as first line treatment in most of the CML patients, but around 30% of them will be resistant to this drug (lack of major molecular response, MMR, among others) and, between those who respond to treatment, only 35%-40% will achieve deep molecular response (DMR). [...]

2021  
10.
149 p, 8.1 MB Prevention of the spread of antibiotic resistance via the structural and molecular study of pLS20 conjugative plasmid proteins / Bernardo, Nerea ; Boer, Roeland D., 1972-, dir. ; Reverter Cendrós, David, dir.
La resistència a antibiòtics està considerada una de les principals amenaces a la salut pública del segle XXI per la OMS. A causa del seu consum excessiu i incorrecte, els bacteris han desenvolupat mecanismes per fer-les front y així, ser capaços de sobreviure a la seva presència. [...]
La resistencia a antibióticos está considerada una de las principales amenazas a la salud pública del siglo XXI por la OMS. Debido a su consumo excesivo e incorrecto, las bacterias desarrollan mecanismos para hacerles frente y así, ser capaces de sobrevivir en su presencia. [...]
Antibiotic Resistance is considered one of the most important public health threats of the 21st century by the WHO. Due to human overuse and misuse of antibiotics, bacteria develop new mechanisms to survive in the presence of antibiotics. [...]

2020  

Documents de recerca : 18 registres trobats   1 - 10següent  anar al registre:
Materials didàctics 2 registres trobats  
1.
10 p, 249.7 KB Writing Biology at University / Ferrandiz-Rovira, Mariona (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Llop Naya, Ares (Universitat Autònoma de Barcelona. Departament de Filologia Catalana) ; Rodrigo Domínguez, Anselm (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Soler Membrives, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Kelso, Fiona Megan (Universitat Autònoma de Barcelona. Servei de Llengües) ; Redmond, Peter (Universitat de Girona. Servei de Llengües Modernes)
User guide to written communication in academic disciplines (in this case biology) for teachers and students.
Bellaterra : Universitat Autònoma de Barcelona, 2023 (Guides for Writing in Specific Disciplines)
2 documents
2.
22 p, 2.1 MB "Mutants plants" workshop protocol : didactic guide for researchers and instructors to conduct a science workshop with groups of school students aged 10 to 14 / Babot, Zoila (Centre de Recerca en Agrigenòmica) ; Martí, Margalida (Centre de Recerca en Agrigenòmica) ; Garrido Espeja, Anna (Universitat Autònoma de Barcelona. Centre de Recerca per a l'Educació Científica i Matemàtica) ; Tena Gallego, Èlia (Universitat Autònoma de Barcelona. Centre de Recerca per a l'Educació Científica i Matemàtica) ; Centre de Recerca en Agrigenòmica ; Universitat Autònoma de Barcelona. Centre de Recerca per a l'Educació Científica i Matemàtica (CRECIM)
The "Mutant Plants" workshop pursues the dual aim of promoting scientific vocations and publicizing the importance of Plant Science to meet current and future societal challenges. This workshop was designed jointly by the Centre for Research in Agricultural Genomics (CRAG) and the Research Centre for Scientific and Mathematical Education (CRECIM) from the Autonomous University of Barcelona (UAB), thanks to the financial support of the Spanish Foundation for Science and Technology (FCT-16-10825) and the Severo Ochoa program of Excellence Centres (SEV-2015-0533), both from the Spanish Ministry of Economy, Industry and Competitiveness.
2017  

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