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1.
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26 p, 3.6 MB |
In vitro approaches to determine the potential carcinogenic risk of environmental pollutants
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Barguilla, Irene (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Maguer-Satta, Veronique (Centre de Recherche en Cancérologie de Lyon) ;
Guyot, Boris (Centre de Recherche en Cancérologie de Lyon) ;
Pastor Benito, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos, Ricard (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernandez, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
One important environmental/health challenge is to determine, in a feasible way, the potential carcinogenic risk associated with environmental agents/exposures. Since a significant proportion of tumors have an environmental origin, detecting the potential carcinogenic risk of environmental agents is mandatory, as regulated by national and international agencies. [...]
2023 -  10.3390/ijms24097851
International journal of molecular sciences, Vol. 24, Issue 9 (April 2023) , art. 7851
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2.
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32 p, 1.1 MB |
Paper-based biosensors for cancer diagnostics
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Pereira, Claudia (Institut Català de Nanociència i Nanotecnologia) ;
Parolo, Claudio (Institut Català de Nanociència i Nanotecnologia) ;
Idili, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Gomis, Roger R. (Institut de Recerca Biomèdica) ;
Rodrigues, Lígia (Universidade do Minho. Centro de Engenharia Biológica) ;
Sales, Goreti (Universidade de Coimbra. Departmento de Enginharia Química) ;
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
The implementation of a wide diagnostic campaign to diagnose cancer early could save millions of lives and billions of dollars every year. Unfortunately, cancer diagnosis is extremely complicated and current approaches rely on the use of expensive equipment and specialized personnel, which hamper their deployment in low- and middle-income settings. [...]
2022 - 10.1016/j.trechm.2022.03.005
Trends in Chemistry, Vol. 4, issue 6 (June 2022) , p. 554-567
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3.
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12 p, 940.6 KB |
Epidemiology, Diagnosis and Management of Penile Cancer : Results from the Spanish National Registry of Penile Cancer
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Borque-Fernando, Ángel (Hospital Universitario Miguel Servet (Saragossa)) ;
Gaya, Josep Maria (Fundació Puigvert) ;
Esteban, Luis M (Applied Mathematics Department, Escuela Universitaria Politécnica de La Almunia, Universidad de Zaragoza, 50100 La Almunia de Doña Godina, Spain) ;
Gómez-Rivas, Juan (Hospital Universitario La Paz (Madrid)) ;
García-Baquero, Rodrigo (Hospital Universitario Puerta del Mar) ;
Agreda Castañeda, Fernando (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gallioli, Andrea (Institut d'Investigació Biomèdica Sant Pau) ;
Verri, Paolo (Fundació Puigvert) ;
Ortiz-Vico, Francisco Javier (Hospital Universitario Principe Asturias) ;
Amir-Nicolau, Balig Fawwaz (Hospital Universitario Nuestra Señora de la Candelaria) ;
Osman-Garcia, Ignacio (Hospital Universitario Virgen del Rocio) ;
Gil-Martínez, Pedro (Hospital Universitario Miguel Servet (Saragossa)) ;
Arrabal-Martín, Miguel (Hospital Universitario Granada) ;
Gómez-Ferrer Lozano, Álvaro (Instituto Valenciano de Urologia (IVO)) ;
Campos-Juanatey, Felix (Hospital Universitario Marques de Valdecilla) ;
Guerrero-Ramos, Félix (Hospital 12 de Octubre (Madrid)) ;
Rubio-Briones, Josè (Clinica de Urología, Hospital VITHAS 9 de Octubre, 46015 Valencia) ;
Universitat Autònoma de Barcelona
Penile cancer is a rare malignant tumor mainly affecting adult/older men. Given the rarity of this disease, affecting 1/100,000 men every year, risk factors and diagnostic procedures are often inadequately described. [...]
2023 - 10.3390/cancers15030616
Cancers, Vol. 15 (january 2023)
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4.
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11 p, 458.4 KB |
Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer
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Yoshino, Takayuki (National Cancer Center Hospital East) ;
Andre, Thierry (Sorbonne University) ;
Kim, Tae Won (University of Ulsan) ;
Yong, Wei Peng (National University Cancer Institute) ;
Shiu, Kai-Keen (University College Hospital) ;
Jensen, Benny Vittrup (Herlev and Gentofte Hospital) ;
Jensen, Lars Henrik (University Hospital of Southern Denmark) ;
Punt, Cornelis J. A. (University Medical Center Utrecht) ;
Smith, Denis (Hôpital Haut-Lévêque) ;
García-Carbonero, Rocío (Imas12, Universidad Complutense de Madrid) ;
Alcaide-Garcia, Julia (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Gibbs, Peter (Western Hospital) ;
de la Fouchardiere, Christelle (Centre Léon Bérard) ;
Rivera, Fernando (Fernando Rivera, University Hospital Marqués de Valdecilla) ;
Elez, Elena (Vall d'Hebron Institut d'Oncologia) ;
Le, Dung T. (Johns Hopkins Medicine) ;
Adachi, Noriaki (Merck (Estats Units d'Amèrica)) ;
Fogelman, David (Merck(Estats Units d'Amèrica)) ;
Marinello, Patricia (Merck (Estats Units d'Amèrica)) ;
Diaz, Luis A. (Memorial Sloan Kettering Cancer Center) ;
Universitat Autònoma de Barcelona
The phase 3 KEYNOTE-177 study evaluated pembrolizumab versus chemotherapy with or without bevacizumab or cetuximab in patients with newly diagnosed, microsatellite-instability-high (MSI-H)/mismatch-repair-deficient (dMMR) metastatic colorectal cancer (mCRC). [...]
2022 - 10.1111/cas.15650
Cancer Science, Vol. 114 (december 2022) , p. 1026-1036
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5.
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15 p, 633.6 KB |
Values and preferences influencing willingness to change red and processed meat consumption in response to evidence-based information : a mixed methods study
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Prokop-Dorner, Anna (Jagiellonian University Medical College) ;
Piłat-Kobla, Aleksandra (Jagiellonian University Medical College) ;
Zając, Joanna (Jagiellonian University Medical College) ;
Luśtyk, Michalina (Jagiellonian University Medical College) ;
Valli, Claudia (Institut d'Investigació Biomèdica Sant Pau) ;
Łapczuk, Aneta (Jagiellonian University Medical College) ;
Brzyska, Monika (Jagiellonian University Medical College) ;
Johnston, Bradley C (Texas A&M University) ;
Zera, Dena (McMaster University (Canadà)) ;
Guyatt, Gordon (McMaster University (Canadà)) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Bala, Malgorzata M. (Jagiellonian University Medical College) ;
Universitat Autònoma de Barcelona
The aim of the study is (1) to assess the extent to which omnivores are willing to stop or reduce their consumption of red and processed meat in response to evidence-based information regarding the possible reduction of cancer mortality and incidence achieved by dietary modification; (2) to identify socio-demographic categories associated with higher willingness to change meat consumption and (3) to understand the motives facilitating and hindering such a change. [...]
2022 - 10.1017/S1368980022000866
Public Health Nutrition, Vol. 25 (august 2022) , p. 2084-2098
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6.
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16 p, 2.7 MB |
Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer
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Prat, Aleix (Hospital Clínic i Provincial de Barcelona) ;
Brasó-Maristany, Fara (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martínez-Sáez, Olga (Universitat de Barcelona) ;
Sanfeliu, Esther (Hospital Clínic i Provincial de Barcelona) ;
Bellet, Meritxell (Vall d'Hebron Institut d'Oncologia) ;
Galván, Patricia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martínez, Débora (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pascual, Tomás (University of North Carolina) ;
Marín-Aguilera, Mercedes (Reveal Genomics (Barcelona)) ;
Rodríguez, Anna (Hospital Clínic i Provincial de Barcelona) ;
Chic, Nuria (Hospital Clínic i Provincial de Barcelona) ;
Adamo, Barbara (Universitat de Barcelona) ;
Paré Brunet, Laia (Reveal Genomics (Barcelona)) ;
Vidal Losada, Maria (Universitat de Barcelona) ;
Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ballana, Ester (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gómez-Rey, Marina (Vall d'Hebron Institut d'Oncologia) ;
Oliveira, Mafalda (Vall d'Hebron Institut d'Oncologia) ;
Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Matito, Judit (Vall d'Hebron Institut d'Oncologia) ;
Sánchez-Bayona, Rodrigo (Hospital Universitario 12 de Octubre (Madrid)) ;
Suñol, Anna (Vall d'Hebron Institut d'Oncologia) ;
Saura, Cristina (Vall d'Hebron Institut d'Oncologia) ;
Ciruelos, Eva (Hospital Universitario 12 de Octubre (Madrid)) ;
Tolosa, Pablo (Hospital Universitario 12 de Octubre (Madrid)) ;
Muñoz, Montserrat (SOLTI cooperative group (Barcelona)) ;
González-Farré, Blanca (Hospital Clínic i Provincial de Barcelona) ;
Villagrasa, Patricia (Reveal Genomics (Barcelona)) ;
Parker, Joel S. (University of North Carolina) ;
Perou, Charles M. (University of North Carolina) ;
Vivancos, Ana (Vall d'Hebron Institut d'Oncologia) ;
Universitat Autònoma de Barcelona
Liquid biopsy has proven valuable in identifying individual genetic alterations; however, the ability of plasma ctDNA to capture complex tumor phenotypes with clinical value is unknown. To address this question, we have performed 0. [...]
2023 - 10.1038/s41467-023-36801-9
Nature communications, Vol. 14 (march 2023)
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14 p, 586.6 KB |
Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing : results of the RING observational trial
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Romero, Atocha (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Jantus-Lewintre, Eloisa (Universitat Politècnica de València) ;
García-Peláez, Beatriz (Hospital Universitari Dexeus (Barcelona, Catalunya)) ;
Royuela, Ana (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Insa, Amelia (Hospital Clínic Universitari (València)) ;
Cruz Castellanos, Patricia (Hospital Universitario La Paz (Madrid)) ;
Collazo-Lorduy, Ana (Hospital Universitario Sanchinarro) ;
Pérez Altozano, Javier (Hospital Virgen de los Lirios) ;
Vidal, Oscar Juan (Hospital Universitari i Politècnic La Fe (València)) ;
Diz, Pilar (Complejo Asistencial Universitario de León) ;
Cobo, Manuel (Hospital Regional Universitario de Málaga) ;
Hernández, Berta (Complejo Hospitalario de Navarra) ;
Vázquez Estevez, Sergio (Hospital Universitario Lucus Augusti (Lugo)) ;
Benítez, Gretel (Complejo Hospitalario Universitario Insular de Gran Canaria) ;
Guirado, Maria (Hospital General Universitario de Elche) ;
Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ;
Bernabé Caro, Reyes (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ortega, Ana Laura (Complejo Hospitalario de Jaén) ;
Blasco, Ana (Centro de Investigación Biomédica en Red de Cáncer) ;
Bosch-Barrera, J (Hospital Dr. Josep Trueta-ICO Girona) ;
Jurado, Jose M. (Hospital Universitario Clínico San Cecilio) ;
García González, Jorge (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Viteri, Santiago (Instituto Oncológico Dr. Rosell. Hospital Universitario Dexeus. Grupo Quiron Salud) ;
Garcia Giron, Carlos (Hospital Universitario de Burgos) ;
Massutí, Bartomeu (Hospital d'Igualada) ;
Lopez Martín, Ana (Hospital Universitario Severo Ochoa) ;
Rodriguez-Festa, Alejandro (Fundación de Investigación Biomédica del H.U. Puerta de Hierro Majadahonda) ;
Calabuig-Fariñas, Silvia (Universitat de València. Departament de Patologia) ;
Molina-Vila, Miguel Ángel (Hospital Universitari Dexeus (Barcelona, Catalunya)) ;
Provencio, Mariano (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
Several platforms for noninvasive EGFR testing are currently used in the clinical setting with sensitivities ranging from 30% to 100%. Prospective studies evaluating agreement and sources for discordant results remain lacking. [...]
2021 - 10.1002/1878-0261.12832
Molecular Oncology, Vol. 15 Núm. 1 (january 2021) , p. 43-56
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8.
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12 p, 1.4 MB |
Prognostic role of intraparotid lymph node metastasis in primary parotid cancer : Systematic review
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Guntinas-Lichius, Orlando (Multidisciplinary Salivary Gland Society) ;
Thielker, Jovanna (Jena University Hospital. Friedrich Schiller University) ;
Robbins, K.Thomas (Southern Illinois University) ;
Olsen, Kerry D. (Mayo Clinic) ;
Shaha, Ashok R. (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ;
Mäkitie, Antti A. (Karolinska Institute and Karolinska Hospital) ;
de Bree, Remco (University Medical Center Utrecht) ;
Vander Poorten, Vincent (University Hospitals Leuven and Department of Oncology. Section Head and Neck Oncology) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Kowalski, Luiz Paulo (Sao Paulo State University Medical School) ;
Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias. Instituto Universitario de Oncología del Principado de Asturias. Universidad de Oviedo) ;
Hamoir, Marc (St Luc University Hospital and King Albert II Cancer Institute. Brussels. Belgium; Institut de Recherche Expérimentale et Clinique (IREC). Université Catholique de Louvain) ;
Ferlito, Alfio (Coordinator of the International Head and Neck Scientific Group)
Background: The prognostic importance of intraparotid lymph node metastasis (P+) in patients with primary parotid gland carcinoma is unclear. Methods: Nineteen retrospective and noncomparative cohort studies, published between 1992 and 2020, met the inclusion criteria and included 2202 patients for this systematic review. [...]
2021 - 10.1002/hed.26541
Head and Neck, Vol. 43 Núm. 3 (march 2021) , p. 997-1008
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9.
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12 p, 1.5 MB |
External validity of docetaxel triplet trials in advanced gastric cancer : are there patients who still benefit?
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Jimenez-Fonseca, Paula (Hospital Universitario Central de Asturias. ISPA) ;
Carmona-Bayonas, Alberto (Fundación Séneca (04515/GERM/06)) ;
Martínez de Castro, Eva (Hospital Universitario Marqués de Valdecilla. IDIVAL) ;
Custodio, Ana (Hospital Universitario La Paz (Madrid)) ;
Pericay Pijaume, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Hernandez-San Gil, Raquel (Hospital Universitario de Canarias (La Laguna)) ;
Aguado, Gema (Hospital General Universitario Gregorio Marañón) ;
Castro Unanua, Natalia (Complejo Hospitalario de Navarra) ;
Cano, Juana María (Hospital General Universitario de Ciudad Real) ;
López López, Flora (Hospital Universitario 12 de Octubre (Madrid)) ;
Garrido Salvo, Marcelo (Pontificia Universidad Católica de Chile) ;
Fernández Montes, Ana (Complejo Hospitalario de Orense) ;
Visa, Laura (Hospital Universitario El Mar) ;
Sánchez Cánovas, Manuel (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Limón, María Luisa (Hospital Universitario Virgen del Rocío) ;
Martínez Lago, Nieves (Complejo Hospitalario Universitario de A Coruña) ;
Pimentel, Paola (Hospital Santa Lucía) ;
Hurtado-Nuño, Alicia (Hospital Universitario Fundación Alcorcón) ;
Azkárate, Aitor (Hospital Universitario Son Espases) ;
Longo, Federico (Hospital Universitario Ramón and Cajal) ;
Díez García, Marc (Hospital Universitari Vall d'Hebron) ;
Arias-Martinez, Aránzazu. (Hospital Universitario Central de Asturias) ;
Saurí Nadal, Tamara (Hospital Clínic i Provincial de Barcelona) ;
Martín Carnicero, Alfonso (Hospital San Pedro de Alcántara) ;
Mangas, Montserrat (Hospital de Galdakao (Usansolo, Biscaia)) ;
Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Granja Ortega, Mónica (Hospital Universitario Clínico San Carlos (Madrid)) ;
Ramchandani, Avinash (Hospital Universitario Insular de Gran Canaria) ;
Hernández Pérez, Carolina (Hospital Universitario Nuestra Señora de la Candelaria) ;
Cerdá, Paula (Centro Médico Tecknon) ;
Gil-Negrete Laborda, Aitziber (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Calvo, Mariona (Institut Català d'Oncologia) ;
Vidal Tocino, Rosario (Complejo Asistencial Universitario de Salamanca. IBSAL) ;
Gallego Plazas, Javier (Hospital General Universitario de Elche)
Background: The purpose of our study was to develop an online calculator to estimate the effect of docetaxel triplets (DPF) in first line of advanced gastric cancer (AGC), and to assess the external validity of docetaxel trials in individual patients. [...]
2021 - 10.1007/s10120-020-01116-x
Gastric Cancer, Vol. 24 Núm. 2 (march 2021) , p. 445-456
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