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Research literature, 1 records found
Research literature 1 records found  
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33 p, 702.8 KB Efficacy of PI3K pathway inhibitors as single agents in metastatic breast cancer / Antunes Melo Oliveira, Ana Mafalda ; Cortés, Javier ; Universitat Autònoma de Barcelona. Departament de Medicina ; Universitat Autònoma de Barcelona. Facultat de Medicina
L'objectiu del cribatge molecular és seleccionar pacients que es beneficiïn especialment de teràpies dirigides. S'analitza l'activitat en monoteràpia de fàrmacs inhibidors de la via de PI3K/AKT/mTOR (PI3Ki) en pacients amb càncer de mama metastàtic (CMM) i s'exploren potencials predictors de benefici clínic. [...]
Molecular prescreening of tumors aim at selecting patients that can benefit most from anticancer targeted-agents. We aimed to assess the activity of single agent PI3K/AKT/mTOR pathway inhibitors (PI3Kpi) in metastatic breast cancer (MBC) patients, and to explore predictors of clinical benefit to these agents. [...]
2013  
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