C-terminal fragment of the tetanus toxin - Search Results

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Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy / Oliván, Sara (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Calvo, Ana Cristina (Universidad de Zaragoza. Facultad de Veterinaria. Laboratorio de Genética Bioquímica) ; Rando, Amaya (Universidad de Zaragoza. Facultad de Veterinaria. Laboratorio de Genética Bioquímica) ; Herrando-Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Manzano Martínez, Raquel (University of Oxford. Department of Physiology, Anatomy and Genetics) ; Zaragoza, Pilar (Universidad de Zaragoza. Instituto Agroalimentario de Aragón) ; Tizzano, Eduardo F. (Hospital Universitari Vall d'Hebron) ; Aguilera, José (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Osta, Rosario (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Spinal muscular atrophy (SMA) is a hereditary childhood disease that causes paralysis and progressive degeneration of skeletal muscles and spinal motor neurons. SMA is associated with reduced levels of full-length Survival of Motor Neuron (SMN) protein, due to mutations in the Survival of Motor Neuron 1 gene. [...]
2016 - DOI (Digital Object Identifier)

10.3389/fnmol.2016.00076
Frontiers in molecular neuroscience, Vol. 9 (August 2016) , art. 76

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