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10 p, 1.7 MB |
Sodium-glucose co-transporter-2 inhibitors in patients with type 2 diabetes : Barriers and solutions for improving uptake in routine clinical practice
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Khunti, Kamlesh (NIHR Applied Research Collaboration - East Midlands) ;
Jabbour, Serge (Thomas Jefferson University) ;
Cos Claramunt, Francesc Xavier (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Mudaliar, Sunder (Veterans Affairs Medical Center) ;
Mende, Christian (University of California San Diego) ;
Bonaca, Marc (University of Colorado School of Medicine) ;
Fioretto, Paola (University of Padua) ;
Universitat Autònoma de Barcelona
Recent advances in type 2 diabetes (T2D) research have highlighted the benefits of sodium-glucose co-transporter-2 (SGLT-2) inhibitors, including cardiovascular and renal protection. However, uptake rates of these drugs remain low in patients with T2D, particularly in subpopulations most likely to benefit from them. [...]
2022 -  10.1111/dom.14684
Diabetes, Obesity and Metabolism, Vol. 24 (march 2022) , p. 1187-1196
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10 p, 1.1 MB |
Risk of infections in patients with NAFLD and Type 2 Diabetes under treatment with SGLT2 inhibitors and relationship with liver outcomes : A retrospective case-control study
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Bañares, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Manzano-Nuñez, Ramiro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prió, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rivera-Esteban, Jesús (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Camps-Relats, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Villarejo, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-Ortega, Lourdes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pons, Mònica (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Ciudin, Andreea (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Salcedo, Maria-Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vargas, Víctor (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Genescà Ferrer, Joan (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Pericàs, Juan M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in developed countries, with its incidence growing parallel to the epidemics of obesity and type 2 diabetes mellitus (T2DM). [...]
2022 - 10.3389/fendo.2022.945626
Frontiers in Endocrinology, Vol. 13 (august 2022)
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14 p, 1.4 MB |
Activation of Immune and Defense Responses in the Intestinal Mucosa by Outer Membrane Vesicles of Commensal and Probiotic Escherichia coli Strains
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Fábrega, María José (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Aguilera, Laura (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Giménez, Rosa (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Varela, Encarna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alexandra Cañas, María (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Antolín, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Badía, Josefa (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Baldomà, Laura (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Universitat Autònoma de Barcelona
The influence of microbiota in human health is well-known. Imbalances in microbiome structure have been linked to several diseases. Modulation of microbiota composition through probiotic therapy is an attempt to harness the beneficial effects of commensal microbiota. [...]
2016 - 10.3389/fmicb.2016.00705
Frontiers in microbiology, Vol. 7 (may 2016)
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16 p, 1.1 MB |
The New Era for Reno-Cardiovascular Treatment in Type 2 Diabetes
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García-Carro, Clara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vergara, Ander (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Agraz Pamplona, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jacobs-Cachá, Conxita (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Espinel Garuz, Eugenia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Seron, Daniel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soler, María José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease in the developed world. Until 2016, the only treatment that was clearly demonstrated to delay the DKD was the renin-angiotensin system blockade, either by angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. [...]
2019 - 10.3390/jcm8060864
Journal of clinical medicine, Vol. 8 (june 2019)
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17 p, 2.0 MB |
Limited Interactions between Streptococcus Suis and Haemophilus Parasuis in In Vitro Co-Infection Studies
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Mathieu-Denoncourt, Annabelle ;
Letendre, Corinne ;
Auger, Jean-Philippe ;
Segura, Mariela ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Lacouture, Sonia ;
Gottschalk, Marcelo
Streptococcus suis and Haemophilus parasuis are normal inhabitants of the porcine upper respiratory tract but are also among the most frequent causes of disease in weaned piglets worldwide, causing inflammatory diseases such as septicemia, meningitis and pneumonia. [...]
2018 - 10.3390/pathogens7010007
Pathogens, Vol. 7 (january 2018)
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