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44 p, 10.1 MB |
Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes
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Mielczarek, O. (Nuclear Dynamics Programme. Babraham Institute. Babraham Research Campus) ;
Rogers, C.H. (Immunology Programme. Babraham Institute. Babraham Research Campus) ;
Zhan, Y. (Friedrich Miescher Institute for Biomedical Research) ;
Matheson, L.S. (Immunology Programme. Babraham Institute. Babraham Research Campus) ;
Stubbington, M.J.T. (Nuclear Dynamics Programme. Babraham Institute. Babraham Research Campus) ;
Schoenfelder, S. (Nuclear Dynamics Programme. Babraham Institute. Babraham Research Campus) ;
Bolland, D.J. (Immunology Programme. Babraham Institute. Babraham Research Campus) ;
Javierre, B. M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Wingett, S.W. (Bioinformatics Group. Babraham Institute. Babraham Research Campus) ;
Várnai, C. (Nuclear Dynamics Programme. Babraham Institute. Babraham Research Campus) ;
Segonds-Pichon, A. (Bioinformatics Group. Babraham Institute. Babraham Research Campus) ;
Conn, S.J. (Flinders Health and Medical Research Institute. College of Medicine and Public Health. Flinders University) ;
Krueger, F. (Babraham Institute) ;
Andrews, S. (Babraham Institute) ;
Fraser, Peter (Nuclear Dynamics Programme. Babraham Institute. Babraham Research Campus) ;
Giorgetti, L. (Friedrich Miescher Institute for Biomedical Research) ;
Corcoran, A.E. (Immunology Programme. Babraham Institute. Babraham Research Campus)
To produce a diverse antibody repertoire, immunoglobulin heavy-chain (Igh) loci undergo large-scale alterations in structure to facilitate juxtaposition and recombination of spatially separated variable (V), diversity (D), and joining (J) genes. [...]
2023 -  10.1016/j.celrep.2023.113074
Cell reports, Vol. 42 Núm. 9 (26 2023) , p. 113074
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9 p, 3.8 MB |
Lactic Acid from CO2 : A Carbon Capture and Utilization Strategy Based on a Biocatalytic Approach
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Carceller, Albert (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Guillén, Marina (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ;
Álvaro, Gregorio (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
The EU low-carbon economy aims to reduce the level of CO emission in the EU to 80% by 2050. High efforts are required to achieve this goal, where successful CCU (Carbon Capture and Utilization) technologies will have a high impact. [...]
2023 - 10.1021/acs.est.3c05455
Environmental Science & Technology, Vol. 57, Issue 51 (December 2023) , p. 21727-21735
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18 p, 6.5 MB |
Value capture and embeddedness in social-purpose-driven ecosystems. A multiple-case study of European digital healthcare platforms
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Pundziene, Asta (Kaunas University of Technology) ;
Gerulaitiene, Neringa (Kaunas University of Technology) ;
Bez, Sea Matilda (University of Montpellie) ;
Georgescu, Irène (University of Montpellie) ;
Mathieu, Christopher (Lund University) ;
Carrabina Bordoll, Jordi (Universitat Autònoma de Barcelona. Departament de Microelectrònica i Sistemes Electrònics) ;
Rialp Criado, Josep (Universitat Autònoma de Barcelona. Departament d'Empresa) ;
Nieminen, Hannu (Tampere University) ;
Varri, Alpo (Tampere University) ;
Boethius, Susanne (Lund University) ;
van Gils, Mark (Tampere University) ;
Giménez, Víctor (Universitat Autònoma de Barcelona. Departament d'Empresa) ;
Narbón Perpiñá, Isabel (Universitat Autònoma de Barcelona. Departament d'Empresa) ;
Prior Jiménez, Diego (Universitat Autònoma de Barcelona. Departament d'Empresa) ;
Vilutiene, Laura (Kaunas University of Technology)
We aim to answer the question of the effect of a social-purpose-driven ecosystem on value capture from digital health platforms. We call the social-purpose-driven ecosystem a phenomenon which seeks social impact before profits and aims to empower citizens for individual and collective well-being. [...]
2023 - 10.1016/j.technovation.2023.102748
Technovation, Vol. 124 (June 2023) , art. 102748
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13 p, 336.2 KB |
Welfare and Clinical Assessment on Physical Captures Followed by Anesthesia in Apennine Chamois (Rupicapra pyrenaica ornata)
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Angelucci, Simone (Maiella National Park. Wildlife Research Center) ;
Antonucci, Antonio (Maiella National Park. Wildlife Research Center) ;
Di Tana, Fabrizia (Maiella National Park. Wildlife Research Center) ;
Innocenti, Marco (Maiella National Park. Wildlife Research Center) ;
Di Domenico, Giovanna (Maiella National Park. Wildlife Research Center) ;
Madonna, Luca (Wildlife Research Center, Maiella National Park. Wildlife Research Center) ;
Smoglica, Camilla (University of Teramo. Faculty of Veterinary Medicine) ;
Di Francesco, Cristina Esmeralda (University of Teramo. Faculty of Veterinary Medicine) ;
López Olvera, Jorge R (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Apennine chamois (Rupicapra pyrenaica ornata) is a vulnerable subspecies, and creation of new colonies is required for its conservation. Capturing mountain ungulates is not only logistically challenging, but also requires careful planning and clinical monitoring in order to ensure animal welfare and survival. [...]
2023 - 10.3390/ani13030460
Animals, Vol. 13 (january 2023)
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8 p, 4.8 MB |
Ammonia capture in rhodium(II)-based metal-organic polyhedra via synergistic coordinative and H-bonding interactions
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Carné-Sánchez, Arnau (Institut Català de Nanociència i Nanotecnologia) ;
Martínez-Esaín, Jordi (Institut Català de Nanociència i Nanotecnologia) ;
Rookard, Tanner (Oregon State University. Department of Chemistry) ;
Flood, Christopher J. (Oregon State University. Department of Chemistry) ;
Faraudo, Jordi (Institut de Ciència de Materials de Barcelona) ;
Stylianou, Kyriakos C (Oregon State University. Department of Chemistry) ;
Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia)
Ammonia (NH) is among the world's most widely produced bulk chemicals, given its extensive use in diverse sectors such as agriculture; however, it poses environmental and health risks at low concentrations. [...]
2023 - 10.1021/acsami.2c19206
ACS applied materials & interfaces, Vol. 15, issue 5 (Feb. 2023) , p. 6747-6754
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10 p, 1.6 MB |
Conversion of CO2 into organic acids by engineered autotrophic yeast
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Baumschabl, Michael (Austrian Centre of Industrial Biotechnology (ACIB)) ;
Ata, Özge (Austrian Centre of Industrial Biotechnology (ACIB)) ;
Mitic, Bernd M. (University of Natural Resources and Life Sciences. Department of Biotechnology, Institute of Microbiology and Microbial Biotechnology) ;
Lutz, Lisa (Austrian Centre of Industrial Biotechnology (ACIB)) ;
Gassler, Thomas (Austrian Centre of Industrial Biotechnology (ACIB)) ;
Troyer, Christina (University of Natural Resources and Life Sciences. Department of Chemistry) ;
Hann, Stephan (Austrian Centre of Industrial Biotechnology (ACIB)) ;
Mattanovich, Diethard (Austrian Centre of Industrial Biotechnology (ACIB))
The increase of CO2 emissions due to human activity is one of the preeminent reasons for the present climate crisis. In addition, considering the increasing demand for renewable resources, the upcycling of CO2 as a feedstock gains an extensive importance to establish CO2-neutral or CO2-negative industrial processes independent of agricultural resources. [...]
2022 - 10.1073/pnas.2211827119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, Num. 47 (November 2022) , art. e2211827119
2 documents
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25 p, 6.6 MB |
Synchrotron-based fourier-transform infrared micro-spectroscopy (SR-FTIRM) fingerprint of the small anionic molecule cobaltabis (dicarbollide) uptake in glioma stem cells
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Nuez-Martínez, Miquel (Institut de Ciència de Materials de Barcelona) ;
Pedrosa, Leire (Hospital Clínic i Provincial de Barcelona) ;
Martínez-Rovira, Immaculada (ALBA Laboratori de Llum de Sincrotró) ;
Yousef, Ibraheem (ALBA Laboratori de Llum de Sincrotró) ;
Diao, Diouldé (Hospital Clínic i Provincial de Barcelona) ;
Teixidor, Francesc (Institut de Ciència de Materials de Barcelona) ;
Stanzani, Elisabetta (Humanitas Research Hospital (Itàlia)) ;
Martínez-Soler, Fina (Institut d'Investigació Biomèdica de Bellvitge) ;
Tortosa, Avelina (Institut d'Investigació Biomèdica de Bellvitge) ;
Sierra, Àngels (Hospital Clínic i Provincial de Barcelona) ;
Gonzalez, José Juan (Hospital Clínic i Provincial de Barcelona) ;
Viñas, Clara (Institut de Ciència de Materials de Barcelona)
The anionic cobaltabis (dicarbollide) [3,3'-Co(1,2-CBH)] −, [ o -COSAN] −, is the most studied icosahedral metallacarborane. The sodium salts of [ o -COSAN] − could be an ideal candidate for the anti-cancer treatment Boron Neutron Capture Therapy (BNCT) as it possesses the ability to readily cross biological membranes thereby producing cell cycle arrest in cancer cells. [...]
2021 - 10.3390/ijms22189937
International journal of molecular sciences, Vol. 22, Issue 18 (September 2021) , art. 9937
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39 p, 4.4 MB |
Population dynamics and genetic connectivity in recent chimpanzee history
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Fontsere, Claudia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Kuhlwilm, Martin (University of Vienna. Human Evolution and Archaeological Sciences) ;
Morcillo-Suarez, Carlos (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Alvarez-Estape, Marina (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Lester, Jack D. (Max Planck Institute for Evolutionary Anthropology) ;
Gratton, Paolo (Università di Roma "Tor Vergata". Dipartimento di Biologia) ;
Schmidt, Joshua M. (The University of Adelaide. School of Biological Sciences) ;
Dieguez, Paula (German Centre for Integrative Biodiversity Research (Halle-Jena-Leipzig, Alemanya)) ;
Aebischer, Thierry (University of Fribourg) ;
Álvarez-Varona, Paula (Jane Goodall Institute Spain and Senegal) ;
Agbor, Anthony (Max Planck Institute for Evolutionary Anthropology) ;
Angedakin, Samuel (Max Planck Institute for Evolutionary Anthropology) ;
Assumang, Alfred K. (Kwame Nkrumah University of Science and Technology. Department of Wildlife and Range Management) ;
Ayimisin, Emmanuel A. (Max Planck Institute for Evolutionary Anthropology) ;
Bailey, Emma (Max Planck Institute for Evolutionary Anthropology) ;
Barubiyo, Donatienne (Max Planck Institute for Evolutionary Anthropology) ;
Bessone, Mattia (Max Planck Institute for Evolutionary Anthropology) ;
Carretero-Alonso, Andrea (Fundación Rainfer) ;
Chancellor, Rebecca (West Chester University. Depts of Anthropology and Sociology and Psychology) ;
Cohen, Heather (Wild Chimpanzee Foundation) ;
Danquah, Emmanuel (Kwame Nkrumah University of Science and Technology. Department of Wildlife and Range Management) ;
Deschner, Tobias (Max Planck Institute for Evolutionary Anthropology) ;
Dunn, Andrew (Wildlife Conservation Society) ;
Dupain, Jef (Antwerp Zoo Foundation) ;
Egbe, Villard E. (Max Planck Institute for Evolutionary Anthropology) ;
Feliu, Olga (Fundació MONA) ;
Goedmakers, Annemarie (Chimbo Foundation) ;
Granjon, Anne-Céline (Max Planck Institute for Evolutionary Anthropology) ;
Head, Josephine (Max Planck Institute for Evolutionary Anthropology) ;
Hedwig, Daniela (Cornell University. K. Lisa Yang Center for Conservation) ;
Hermans, Veerle (Royal Zoological Society of Antwerp) ;
Hernandez-Aguilar, R. Adriana (Universitat de Barcelona. Departament de Psicologia Social i Psicologia Quantitativa) ;
Imong, Inaoyom (Wildlife Conservation Society) ;
Jones, Sorrel (RSPB Centre of Conservation Science) ;
Junker, Jessica (German Centre for Integrative Biodiversity Research (Halle-Jena-Leipzig, Alemanya)) ;
Kadam, Parag (Greater Mahale Ecosystem Research and Conservation Project) ;
Kaiser, Mike (Max Planck Institute for Evolutionary Anthropology) ;
Kambere, Mbangi (Max Planck Institute for Evolutionary Anthropology) ;
Kambale, Magloire V. (Max Planck Institute for Evolutionary Anthropology) ;
Kalan, Ammie K. (University of Victoria. Department of Anthropology) ;
Kienast, Ivonne (Max Planck Institute for Evolutionary Anthropology) ;
Kujirakwinja, Deo (Wildlife Conservation Society) ;
Langergraber, Kevin (Arizona State University) ;
Lapuente, Juan (Max Planck Institute for Evolutionary Anthropology) ;
Larson, Bradley (Max Planck Institute for Evolutionary Anthropology) ;
Laudisoit, Anne (Evolutionary Ecology group) ;
Lee, Kevin (Arizona State University. School of Human Evolution and Social Change) ;
Llana, Manuel (Jane Goodall Institute Spain and Senegal) ;
Llorente, Miquel (Universitat de Girona. Departament de Psicologia) ;
Marrocoli, Sergio (Max Planck Institute for Evolutionary Anthropology) ;
Morgan, David (Lester E. Fisher Center for the Study and Conservation of Apes) ;
Mulindahabi, Felix (Wildlife Conservation Society) ;
Murai, Mizuki (Max Planck Institute for Evolutionary Anthropology) ;
Neil, Emily (Max Planck Institute for Evolutionary Anthropology) ;
Nicholl, Sonia (Max Planck Institute for Evolutionary Anthropology) ;
Nixon, Stuart (Chester Zoo) ;
Normand, Emma (Wild Chimpanzee Foundation) ;
Orbell, Chris (Panthera) ;
Ormsby, Lucy J. (Max Planck Institute for Evolutionary Anthropology) ;
Pacheco, Liliana (Centres Molina) ;
Piel, Alex (University College London. Department of Anthropology) ;
Riera, Laura (Fundació MONA) ;
Robbins, Martha M. (Max Planck Institute for Evolutionary Anthropology) ;
Rundus, Aaron (West Chester University. Department of Psychology) ;
Sanz, Crickette (Wildlife Conservation Society) ;
Sciaky, Lilah (Max Planck Institute for Evolutionary Anthropology) ;
Sommer, Volker (Primate Project) ;
Stewart, Fiona A. (Liverpool John Moores University. School of Biological & Environmental Sciences) ;
Tagg, Nikki (Royal Zoological Society of Antwerp) ;
Tédonzong, Luc Roscelin (Royal Zoological Society of Antwerp) ;
Ton, Els (Chimbo Foundation) ;
van Schijndel, Joost (Chimbo Foundation) ;
Vergnes, Virginie (Wild Chimpanzee Foundation) ;
Wessling, Erin G. (Harvard University. Department of Human Evolutionary Biology) ;
Willie, Jacob (Ghent University. Department of Biology) ;
Wittig, Roman M. (Taï Chimpanzee Project) ;
Yuh, Yisa G. (University of Concordia. Department of Geography, Planning and Environmental Studies) ;
Yurkiw, Kyle (Max Planck Institute for Evolutionary Anthropology) ;
Zuberbuehler, Klaus (University of St. Andrews. School of Psychology and Neuroscience) ;
Hecht, Jochen (Institut de Ciència i Tecnologia de Barcelona) ;
Vigilant, Linda (Max Planck Institute for Evolutionary Anthropology) ;
Boesch, Christophe (Max Planck Institute for Evolutionary Anthropology) ;
Andrés, Aida M. (University College London. Department of Genetics, Evolution and Environment) ;
Hughes, David A. (University of Bristol. Bristol Medical School) ;
Kühl, Hjalmar S. (German Centre for Integrative Biodiversity Research (Halle-Jena-Leipzig, Alemanya)) ;
Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont) ;
Arandjelovic, Mimi (German Centre for Integrative Biodiversity Research (Halle-Jena-Leipzig, Alemanya)) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont)
Knowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we produced the first non-invasive geolocalized catalog of genomic diversity by capturing chromosome 21 from 828 non-invasive samples collected at 48 sampling sites across Africa. [...]
2022 - 10.1016/j.xgen.2022.100133
Cell Genomics, Vol. 2, Issue 6 (June 2022) , art. 100133
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