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11 p, 1.4 MB |
Sex differential impact of comorbidities in spondyloarthritis : data from COMOSPA study
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Llop, Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Moreno Martínez-Losa, Mireia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Arévalo Salaet, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Calvet, Joan (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Berenguer-Llergo, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Dougados, Maxime (Hospital Cochin) ;
Molto, Anna (Hospital Cochin) ;
López-Medina, Clementina (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Universitat Autònoma de Barcelona
To describe and compare the prevalence of comorbidities in female and male patients with spondyloarthritis (SpA) and to assess whether comorbidities had a different impact on disease outcomes in male and female patients. [...]
2024 -  10.1136/rmdopen-2023-003776
RMD Open, Vol. 10 (january 2024)
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16 p, 1.1 MB |
Endothelial activation and damage as a common pathological substrate in different pathologies and cell therapy complications
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Palomo, Marta (Hospital Clínic i Provincial de Barcelona) ;
Moreno-Castaño, Ana Belén (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Salas, María Queralt (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Escribano-Serrat, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rovira, Montserrat (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Guillen-Olmos, Elena (Hospital Clínic i Provincial de Barcelona) ;
Fernandez, Sara (Hospital Clínic i Provincial de Barcelona) ;
Ventosa-Capell, Helena (Hospital Clínic i Provincial de Barcelona) ;
Youssef, Lina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Crispi, Fatima (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Nomdedeu, Meritxell (Hospital Clínic i Provincial de Barcelona) ;
Martinez-Sanchez, Julia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
De Moner, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Diaz-Ricart, Maribel (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
The endothelium is a biologically active interface with multiple functions, some of them common throughout the vascular tree, and others that depend on its anatomical location. Endothelial cells are continually exposed to cellular and humoral factors, and to all those elements (biological, chemical, or hemodynamic) that circulate in blood at a certain time. [...]
2023 - 10.3389/fmed.2023.1285898
Frontiers in Medicine, Vol. 10 (2023) , p. 1285898
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7 p, 866.4 KB |
C-reactive protein in atherothrombosis and angiogenesis
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Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Peña, Esther (Institut d'Investigació Biomèdica Sant Pau) ;
Arderiu, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Padró, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Slevin, M. (Manchester Metropolitan University) ;
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Chiva-Blanch, Gemma (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation, or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions. This review is focused on discussing the role of CRP in cardiovascular disease, including recent advances on the implication of CRP and its forms specifically on the pathogenesis of atherothrombosis and angiogenesis. [...]
2018 - 10.3389/fimmu.2018.00430
Frontiers in immunology, Vol. 9 Núm. MAR (february 2018) , p. 430
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10 p, 701.1 KB |
Circulating non-coding RNAs in biomarker-guided cardiovascular therapy : A novel tool for personalized medicine?
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Gonzalo Calvo, David de (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vea, Ángela (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bär, C. (Hannover Medical School) ;
Fiedler, J. (Hannover Medical School) ;
Couch, L.S. (Imperial College London) ;
Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Llorente-Cortes, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ;
Thum, T. (Hannover Medical School) ;
Universitat Autònoma de Barcelona
Current clinical guidelines emphasize the unmet need for technological innovations to guide physician decision-making and to transit from conventional care to personalized cardiovascular medicine. Biomarker-guided cardiovascular therapy represents an interesting approach to inform tailored treatment selection and monitor ongoing efficacy. [...]
2019 - 10.1093/eurheartj/ehy234
European heart journal, Vol. 40 Núm. 20 (january 2019) , p. 1643-1650
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12 p, 1.4 MB |
High adherence to the nordic diet is associated with lower levels of total and platelet-derived circulating microvesicles in a norwegian population
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Chiva-Blanch, Gemma (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Laake, Kristian (University of Oslo) ;
Myhre, Peder (University of Oslo) ;
Bratseth, Vibeke (University of Oslo) ;
Arnesen, Harald (University of Oslo) ;
Solheim, Svein (Oslo University Hospital Ullevål) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Seljeflot, Ingebjorg (University of Oslo) ;
Universitat Autònoma de Barcelona
Circulating microvesicles (cMV) are small phospholipid-rich blebs shed from the membrane of activated vascular cells that contribute to vascular disease progression. We aimed to investigate whether the quality of the Nordic diet is associated with the degree of blood and vascular cell activation measured by MV shedding in elderly patients after an acute myocardial infarction (AMI). [...]
2019 - 10.3390/nu11051114
Nutrients, Vol. 11 Núm. 5 (may 2019) , p. 1114
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24 p, 1.1 MB |
Highlights from the 2019 International Aspirin Foundation Scientific Conference, Rome, 28 June 2019 : Benefits and risks of antithrombotic therapy for cardiovascular disease prevention
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Walker, Jaqui (International Aspirin Foundation) ;
Cattaneo, Marco (Università degli studi di Milano) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Agnelli, Giancarlo (University of Perugia) ;
Chan, Andrew T. (Harvard Medical School) ;
Lanas, Angel (Universidad de Zaragoza) ;
Rocca, Bianca (Catholic University School of Medicine) ;
Rothwell, Peter (Centre for the Prevention of Stroke and Dementia) ;
Patrignani, Paola ('G.d'Annunizio' University) ;
Langley, Ruth (MRC Clinical Trials Unit at UCL) ;
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Cosentino, Francesco (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Universitat Autònoma de Barcelona
At the 2019 International Aspirin Foundation Scientific Conference 'Benefits and Risks of Antithrombotic Therapy for Cardiovascular Disease Prevention', held in Rome, Italy, international experts sought to discuss and debate the optimal antithrombotic strategy for the secondary prevention of cardiovascular disease (CVD) and to seek agreement around dosing and target populations for aspirin use in primary disease prevention. [...]
2020 - 10.3332/ECANCER.2019.998
ecancermedicalscience, Vol. 14 (13 2020) , p. 998
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9 p, 1.8 MB |
Clinical Prognosis of Right-Sided Infective Endocarditis not Associated with Cardiac Devices or Intravenous Drug use : a Cohort Study and Meta-Analysis
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Rigau, Pau Vilardell (Hospital Universitari de Girona Doctor Josep Trueta) ;
Moral, Sergio (Hospital Universitari de Girona Doctor Josep Trueta) ;
Bosch, Daniel (Hospital Universitari de Girona Doctor Josep Trueta) ;
Morales, Manel (Hospital Universitari de Girona Doctor Josep Trueta) ;
Frigola, Josep Maria (Hospital Universitari de Girona Doctor Josep Trueta) ;
Albert, Xavier (Hospital Universitari de Girona Doctor Josep Trueta) ;
Robles, Rocío (Hospital Universitari de Girona Doctor Josep Trueta) ;
Ballesteros, Esther (Institut Català de la Salut) ;
Roqué i Figuls, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Aboal, Jaime (Hospital Universitari de Girona Doctor Josep Trueta) ;
Brugada, Ramon (Hospital Universitari de Girona Doctor Josep Trueta) ;
Universitat Autònoma de Barcelona
Right-sided infective endocarditis (RSIE), classically associated with intravenous drug use or intracardiac devices, is considered a good-prognosis infective endocarditis (IE) form. However, predisposing factors and prognosis for "NODID" RSIE (NOt associated with cardiac Devices or Intravenous Drug use) remain unclear. [...]
2020 - 10.1038/s41598-020-64220-z
Scientific reports, Vol. 10 Núm. 1 (january 2020) , p. 7179
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