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1.
12 p, 700.5 KB Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain : OSIREX-Spanish Lung Cancer Group / Provencio, Mariano (Universidad Autónoma de Madrid) ; Terrasa, Josefa (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Garrido, Pilar (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Campelo, Rosario García (Instituto de Investigación Biomédica A Coruña INIBIC) ; Aparisi, Francisco (Hospital General Universitario de Valencia) ; Diz, Pilar (Complejo Asistencial Universitario de León. Medical Oncology Department León) ; Aguiar, David (Hospital Universitario de Gran Canaria Dr. Negrín) ; García-Giron, Carlos (Hospital Universitario de Burgos) ; Hidalgo, Julia (Hospital Lluís Alcanyis. Medical Oncology Department) ; Aguado, Carlos (Hospital Clínico San Carlos (Madrid)) ; González, Jorge García (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Esteban, Emilio (Hospital Universitario Central de Asturias. Medical Oncology Department) ; Gómez-Aldavarí, Lorenzo (Complejo Hospitalario Universitario de Albacete) ; Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Juan, Oscar (Hospital Universitari i Politècnic La Fe de València) ; Chara, Luís Enrique (Hospital Universitario de Guadalajara) ; Marti, Juan L. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Castro, Rafael López (Hospital Clínico Universitario (Valladolid)) ; Ortega, Ana Laura (Complejo Hospitalario de Jaén) ; Moreno, Elia Martínez (Hospital Virgen de la Salud (Toledo)) ; Coves, Juan (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ; Sánchez Peña, Ana M. (Hospital Universitario de Getafe (Madrid)) ; Bosch-Barrera, Joaquim (Hospital Universitari de Girona Doctor Josep Trueta) ; Gastaldo, Amparo Sánchez (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Núñez, Natalia Fernández (Hospital Universitario Lucus Augusti (Lugo)) ; del Barco, Edel (Hospital Universitario de Salamanca) ; Cobo, Manuel (Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Unidad de Gestión Clínica Intercentros de Oncología Médica) ; Isla, Dolores (Hospital Universitario Lozano Blesa. Medical Oncology Department) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Navarro, Fátima (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ; Calvo, Virginia (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Universitat Autònoma de Barcelona
AURA study reported 61% objective response rate and progression-free survival of 9. 6 months with osimertinib in patients with EGFR/T790M+ non-small cell lung cancer. Due to lack of real-world data, we proposed this study to describe the experience with osimertinib in Spain. [...]
2021 - 10.1186/s12885-021-07922-5
BMC Cancer, Vol. 21 (march 2021)  
2.
14 p, 2.0 MB Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bywater, M.J. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Sanij, E. (Department of Pathology. University of Melbourne) ; Cameron, D.P. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Schierding, W. (Liggins Institute. The University of Auckland) ; Brajanovski, N. (Cancer Research Division. Peter MacCallum Cancer Centre) ; Son, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Sornkom, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Hein, N. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Evers, M. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Pearson, R.B. (Department of Biochemistry and Molecular Biology. University of Melbourne) ; McArthur, G.A. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Ganley, A.R.D. (School of Biological Sciences. The University of Auckland) ; O'Sullivan, J.M. (Liggins Institute. The University of Auckland) ; Hannan, R.D. (School of Biomedical Sciences. University of Queensland) ; Poortinga, G. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Universitat Autònoma de Barcelona
The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain unclear. [...]
2019 - 10.1038/s42003-019-0284-y
Communications Biology, Vol. 2 Núm. 1 (january 2019) , p. 39  
3.
16 p, 2.3 MB SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina / Vazquez Prat, Berta Nieves (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Thackray, J.K. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Simonet, N.G. (Institut d'Investigació Biomèdica de Bellvitge) ; Chahar, S. (Montpellier Institute of Molecular Genetics (IGMM). CNRS. University of Montpellier) ; Kane-Goldsmith, N. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Newkirk, S.J. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Lee, S. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Xing, J. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Verzi, M.P. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; An, W. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Tischfield, J.A. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Serrano, L. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Universitat Autònoma de Barcelona
Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of self-propagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how this process becomes dysfunctional during aging and in cancer cells is poorly understood. [...]
2019 - 10.1093/nar/gkz519
Nucleic acids research, Vol. 47 Núm. 15 (january 2019) , p. 7870-7885  
4.
11 p, 1.9 MB Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma / Recasens-Zorzo, C. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Cardesa-Salzmann, T. (Hospital Clínic i Provincial de Barcelona) ; Petazzi, Paolo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ros-Blanco, L. (Universitat Ramon Llull. Institut Químic de Sarrià-IQS) ; Esteve-Arenys, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Clot, G. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Guerrero-Hernández, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rodríguez, V. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Soldini, D. (Hospital Clínic i Provincial de Barcelona) ; Valera, A. (Hospital Clínic i Provincial de Barcelona) ; Moros, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Climent, F. (Hospital Universitari de Bellvitge) ; González-Barca, E. (Institut Català d'Oncologia) ; Mercadal, Santiago (Institut Català d'Oncologia) ; Arenillas, Leonor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Calvo, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mate, J.L. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gutiérrez-García, G. (Hospital Clínic i Provincial de Barcelona) ; Casanova Rigat, Isolda (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mangues, Ramon (Institut d'Investigació Biomèdica Sant Pau) ; Sanjuan-Pla, A. (Hospital Universitari i Politècnic La Fe de València) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martínez, A. (Hospital Clínic i Provincial de Barcelona) ; Colomer, D. (Hospital Clínic i Provincial de Barcelona) ; Tejedor, R.E. (Universitat Ramon Llull) ; Teixidó, J. (Universitat Ramon Llull) ; Campo, E. (Hospital Clínic i Provincial de Barcelona) ; López-Guillermo, A. (Hospital Clínic i Provincial de Barcelona) ; Borrell, J.I. (Universitat Ramon Llull) ; Colomo, Luis (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pérez-Galán, P. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Roué, Gaël (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer subtypes. Although the CXCR4 pathway has recently been suggested as an adverse prognostic marker in diffuse large B-cell lymphoma, its biological relevance in this disease remains underexplored. [...]
2019 - 10.3324/haematol.2017.180505
Haematologica, Vol. 104 Núm. 4 (31 2019) , p. 778-788  
5.
18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Sintef Industry. Department of Biotechnology and Nanomedicine) ; Benítez-Buelga, C. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Cázares-Körner, A. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Sanjiv, K. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Hanna, B.M.F. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Mortusewicz, O. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Rajagopal, V. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Albers, J.J. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Hagey, D.W. (Karolinska Institutet (Estocolm, Suècia). Department of Laboratory Medicine) ; Bekkhus, T. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Eshtad, S. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Baquero, J.M. (Centro Nacional de Investigaciones Oncológicas) ; Masuyer, G. (University of Bath. Department of Pharmacy and Pharmacology) ; Wallner, O. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Müller, S. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Pham, T. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Göktürk, C. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Rasti, A. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Suman, S. (Karolinska Institutet. Department of Oncology and Pathologyt) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Sintef Ocean. Department of Environment and New Resources) ; Wiita, E. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Homan, E.J. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Karsten, S. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Marimuthu, K. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Michel, M. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Koolmeister, T. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Scobie, M. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Loseva, O. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Almlöf, I. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Unterlass, J.E. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Pettke, A. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Boström, J. (Karolinska Institutet (Estocolm, Suècia). Department of Laboratory Medicine) ; Pandey, M. (University of Sheffield. Weston Park Cancer Centre) ; Gad, H. (University of Sheffield. Weston Park Cancer Centre) ; Herr, P. (University of Sheffield. Weston Park Cancer Centre) ; Jemth, A.S. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; El Andaloussi, S. (Karolinska Institutet (Estocolm, Suècia). Department of Laboratory Medicine) ; Kalderén, C. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Rodriguez-Perales, S. (Centro Nacional de Investigaciones Oncológicas) ; Benítez, J. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Krokan, H.E. (Research and Innovation in Central Norway) ; Altun, M. (Karolinska Institutet (Estocolm, Suècia). Department of Laboratory Medicine) ; Stenmark, P. (Lund University. Department of Experimental Medical Science.) ; Berglund, U.W. (Karolinska Institutet (Estocolm, Suècia). Department of Oncology and Pathology) ; Helleday, T. (University of Sheffield.Weston Park Cancer Centre) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
6.
9 p, 1.7 MB Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles / Pesarrodona Roches, Mireia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Crosas, Eva (ALBA Laboratori de Llum de Sincrotró) ; Cubarsi, Rafael (Universitat Politècnica de Catalunya. Departament de Matemàtiques) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Saccardo, Paolo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Unzueta Elorza, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ; Rueda, Fabian (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sánchez García, Laura (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Serna Romero, Naroa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mangues, Ramon (Institut d'Investigació Biomèdica Sant Pau) ; Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona
Self-assembling proteins are gaining attention as building blocks for application-tailored nanoscale materials. This is mostly due to the biocompatibility, biodegradability, and functional versatility of peptide chains. [...]
2017 - 10.1039/c6nr09182b
Nanoscale, Vol. 9, issue 19 (May 2017) , p. 6427-6435  
7.
13 p, 1.1 MB Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity / Sant'Anna, Ricardo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gallego Alonso, Pablo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Robinson, Lei Z. (Scripps Research Institute) ; Pereira-Henriques, Alda (Instituto de Ciências Biomédicas de Abel Salazar (Porto, Portugal)) ; Ferreira, Nelson (Instituto de Ciências Biomédicas de Abel Salazar (Porto, Portugal)) ; Pinheiro, Francisca (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Esperante, Sebastián (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pallarès i Goitiz, Irantzu (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Huertas, Oscar (SOM-Biotech) ; Almeida, Maria Rosário (Instituto de Ciências Biomédicas de Abel Salazar (Porto, Portugal)) ; Reixach, Natàlia (Scripps Research Institute) ; Insa, Raul (SOM-Biotech) ; Velazquez-Campoy, Adrián (Universidad de Zaragoza. Departamento de Bioquímica y Biología Celular y Molecular) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Reig, Núria (SOM-Biotech) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggregation. Native state stabilizers are promising drugs to treat TTR amyloidoses. [...]
2016 - 10.1038/ncomms10787
Nature communications, Vol. 7 (2016) , art. 10787  
8.
10 p, 1.9 MB Studying the complex expression dependences between sets of coexpressed genes / Huerta Casado, Mario (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casanova, Oriol (Universitat Autònoma de Barcelona. Escola d'Enginyeria) ; Barchino, Roberto (Universitat Autònoma de Barcelona. Escola d'Enginyeria) ; Flores, José (Universitat Autònoma de Barcelona. Escola d'Enginyeria) ; Querol Murillo, Enrique (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología)
Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. The use of clustering methods to obtain sets of coexpressed genes from expression arrays is very common; nevertheless there are no appropriate tools to studge the expression networks among these sets of coexpressed genes. [...]
2014 - 10.1155/2014/940821
BioMed Research International, Vol. 2014 (2014) , art. 940821  
9.
11 p, 871.5 KB Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors / Powers, R.K. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Culp-Hill, R. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Ludwig, M.P. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Smith, K.P. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Waugh, K.A. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Minter, R. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Tuttle, K.D. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Lewis, H.C. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Rachubinski, A.L. (Department of Pediatrics. University of Colorado Anschutz Medical Campus) ; Granrath, R.E. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ; Wilkerson, R.B. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Kahn, D.E. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Joshi, M. (Functional Genomics Facility. University of Colorado Anschutz Medical Campus) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; D'Alessandro, A. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Costello, J.C. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Sullivan, K.D. (Functional Genomics Facility. University of Colorado Anschutz Medical Campus) ; Espinosa, J.M. (Department of Molecular. Cellular and Developmental Biology. University of Colorado Boulder) ; Universitat Autònoma de Barcelona
Trisomy 21 (T21) causes Down syndrome (DS), affecting immune and neurological function by ill-defined mechanisms. Here we report a large metabolomics study of plasma and cerebrospinal fluid, showing in independent cohorts that people with DS produce elevated levels of kynurenine and quinolinic acid, two tryptophan catabolites with potent immunosuppressive and neurotoxic properties, respectively. [...]
2019 - 10.1038/s41467-019-12739-9
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 4766  
10.
5 p, 1.1 MB Caveats and pitfalls of SOX1 autoantibody testing with a commercial line blot assay in paraneoplastic neurological investigations / Ruiz-García, R. (Institut d'Investigació Biomèdica de Bellvitge) ; Martínez-Hernández, E. (Hospital Clínic i Provincial de Barcelona) ; García-Ormaechea, M. (Institut d'Investigació Biomèdica de Bellvitge) ; Español-Rego, M. (Institut d'Investigació Biomèdica de Bellvitge) ; Sabater, L. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Querol, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Illa, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Dalmau, J. (Department of Neurology. University of Pennsylvania) ; Graus Ribas, Francesc (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Universitat Autònoma de Barcelona
SOX1 autoantibodies are considered markers of small cell lung cancer (SCLC) and paraneoplastic neurological syndromes (PNS) and are usually determined by commercial line blot in many clinical services. [...]
2019 - 10.3389/fimmu.2019.00769
Frontiers in immunology, Vol. 10 Núm. APR (2019) , p. 769  

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