Resultats globals: 16 registres trobats en 0.03 segons.
Articles, 16 registres trobats
Articles 16 registres trobats  1 - 10següent  anar al registre:
1.
12 p, 700.5 KB Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain : OSIREX-Spanish Lung Cancer Group / Provencio, Mariano (Universidad Autónoma de Madrid) ; Terrasa, Josefa (Hospital Universitari Son Espases. Medical Oncology Department) ; Garrido, Pilar (IRYCIS Hospital Universitario Ramón y Cajal. Medical Oncology Department) ; Campelo, Rosario García (Instituto de Investigación Biomédica A Coruña INIBIC) ; Aparisi, Francisco (Hospital General Universitario de Valencia. Medical Oncology Department Valencia) ; Diz, Pilar (Complejo Asistencial Universitario de León. Medical Oncology Department León) ; Aguiar, David (Hospital Universitario de Gran Canaria Dr. Negrín. Medical Oncology Department) ; García-Giron, Carlos (Hospital Universitario De Burgos. Medical Oncology Department) ; Hidalgo, Julia (Hospital Lluís Alcanyis. Medical Oncology Department) ; Aguado, Carlos (Hospital Clínico San Carlos. Medical Oncology Department) ; González, Jorge García (Hospital Clínico Universitario de Santiago. Medical Oncology Department Santiago de Compostela) ; Esteban, Emilio (Hospital Universitario Central de Asturias. Medical Oncology Department) ; Gómez-Aldavarí, Lorenzo (Complejo Hospitalario Universitario de Albacete. Medical Oncology Department) ; Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Juan, Oscar (Hospital Universitari i Politècnic La Fe. Medical Oncology Department) ; Chara, Luís Enrique (Hospital Universitario de Guadalajara. Medical Oncology Department) ; Marti, Juan L. (Hospital General Universitario de Alicante. Medical Oncology Department) ; Castro, Rafael López (Hospital Clínico Universitario de Valladolid. Medical Oncology Department) ; Ortega, Ana Laura (Complejo Hospitalario de Jaen. Medical Oncology Department) ; Moreno, Elia Martínez (Hospital Virgen de la Salud. Medical Oncology Department) ; Coves, Juan (Hospital Son Llàtzer. Medical Oncology Department) ; Sánchez Peña, Ana M. (Hospital Universitario de Getafe. Medical Oncology Department) ; Bosch-Barrera, Joaquim (Catalan Institute of Oncology. Dr. Josep Trueta University Hospital. Department of Oncology) ; Gastaldo, Amparo Sánchez (Hospital Universitario Virgen del Rocío. Medical Oncology Department) ; Núñez, Natalia Fernández (Hospital Universitario Lucus Augusti. Medical Oncology Department) ; del Barco, Edel (Hospital Universitario de Salamanca. Medical Oncology Department) ; Cobo, Manuel (Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Unidad de Gestión Clínica Intercentros de Oncología Médica) ; Isla, Dolores (Hospital Universitario Lozano Blesa. Medical Oncology Department) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Navarro, Fátima (Hospital Universitario Príncipe de Asturias. Medical Oncology Department) ; Calvo, Virginia (Health Research Institute, Hospital Universitario Puerta de Hierro) ; Universitat Autònoma de Barcelona
AURA study reported 61% objective response rate and progression-free survival of 9. 6 months with osimertinib in patients with EGFR/T790M+ non-small cell lung cancer. Due to lack of real-world data, we proposed this study to describe the experience with osimertinib in Spain. [...]
2021 - 10.1186/s12885-021-07922-5
BMC Cancer, Vol. 21 (march 2021)  
2.
14 p, 2.0 MB Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bywater, M.J. (QIMR Berghofer Medical Research Institute) ; Sanij, E. (Department of Pathology. University of Melbourne) ; Cameron, D.P. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Schierding, W. (Liggins Institute. The University of Auckland) ; Brajanovski, N. (Cancer Research Division. Peter MacCallum Cancer Centre) ; Son, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Sornkom, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Hein, N. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Evers, M. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Pearson, R.B. (Department of Biochemistry and Molecular Biology. University of Melbourne) ; McArthur, G.A. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Ganley, A.R.D. (School of Biological Sciences. The University of Auckland) ; O'Sullivan, J.M. (Liggins Institute. The University of Auckland) ; Hannan, R.D. (School of Biomedical Sciences. University of Queensland) ; Poortinga, G. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Universitat Autònoma de Barcelona
The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain unclear. [...]
2019 - 10.1038/s42003-019-0284-y
Communications Biology, Vol. 2 Núm. 1 (january 2019) , p. 39  
3.
16 p, 2.3 MB SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina / Vazquez Prat, Berta Nieves (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Thackray, J.K. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Simonet, N.G. (Chromatin Biology Laboratory. Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL)) ; Chahar, S. (Montpellier Institute of Molecular Genetics (IGMM). CNRS. University of Montpellier) ; Kane-Goldsmith, N. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Newkirk, S.J. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Lee, S. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Xing, J. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Verzi, M.P. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; An, W. (Department of Pharmaceutical Sciences. College of Pharmacy and Allied Health Professions. South Dakota State University) ; Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Tischfield, J.A. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Serrano, L. (Department of Genetics. Human Genetics Institute of New Jersey. Rutgers University) ; Universitat Autònoma de Barcelona
Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of self-propagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how this process becomes dysfunctional during aging and in cancer cells is poorly understood. [...]
2019 - 10.1093/nar/gkz519
Nucleic acids research, Vol. 47 Núm. 15 (january 2019) , p. 7870-7885  
4.
11 p, 1.9 MB Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma / Recasens-Zorzo, C. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Cardesa-Salzmann, T. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; Petazzi, Paolo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ros-Blanco, L. (Grup d'Enginyeria Molecular. IQS School of Engineering. Universitat Ramon Llull) ; Esteve-Arenys, A. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Clot, G. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Guerrero-Hernández, M. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Rodríguez, V. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Soldini, D. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; Valera, A. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; Moros, A. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Climent, F. (Pathology Department. Hospital Universitari de Bellvitge) ; González-Barca, E. (Institut Català d'Oncologia) ; Mercadal, S. (Institut Català d'Oncologia) ; Arenillas, Leonor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Calvo, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mate, J.L. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gutiérrez-García, G. (Department of Hematology. Hospital Clinic) ; Casanova Rigat, Isolda (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mangues, Ramon (Institut d'Investigació Biomèdica Sant Pau) ; Sanjuan-Pla, A. (Hematology Research Group. Health Research Institute La Fe) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martínez, A. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; Colomer, D. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; Tejedor, R.E. (Grup d'Enginyeria Molecular. IQS School of Engineering. Universitat Ramon Llull) ; Teixidó, J. (Grup d'Enginyeria Molecular. IQS School of Engineering. Universitat Ramon Llull) ; Campo, E. (Hematopathology Unit. Department of Pathology. Hospital Clinic) ; López-Guillermo, A. (Department of Hematology. Hospital Clinic) ; Borrell, J.I. (Grup d'Enginyeria Molecular. IQS School of Engineering. Universitat Ramon Llull) ; Colomo, Luís (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pérez-Galán, P. (Division of Hemato-Oncology. Institut d'Investigacions Biomediques August Pi I Sunyer (IDIBAPS). CIBERONC) ; Roué, Gaël (VHIO) ; Universitat Autònoma de Barcelona
Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer subtypes. Although the CXCR4 pathway has recently been suggested as an adverse prognostic marker in diffuse large B-cell lymphoma, its biological relevance in this disease remains underexplored. [...]
2019 - 10.3324/haematol.2017.180505
Haematologica, Vol. 104 Núm. 4 (31 2019) , p. 778-788  
5.
18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Department of Biotechnology and Nanomedicine. Sintef Industry) ; Benítez-Buelga, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Cázares-Körner, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Sanjiv, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hanna, B.M.F. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Mortusewicz, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rajagopal, V. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Albers, J.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hagey, D.W. (Department of Laboratory Medicine. Karolinska Institutet) ; Bekkhus, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Eshtad, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Baquero, J.M. (Human Genetics Group. Spanish National Cancer Research Centre (CNIO)) ; Masuyer, G. (Department of Pharmacy and Pharmacology. Centre for Therapeutic Innovation. University of Bath) ; Wallner, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Müller, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pham, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Göktürk, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rasti, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Suman, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Department of Environment and New Resources. Sintef Ocean) ; Wiita, E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Homan, E.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Karsten, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Marimuthu, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Michel, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Koolmeister, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Scobie, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Loseva, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Almlöf, I. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Unterlass, J.E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pettke, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Boström, J. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Pandey, M. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Gad, H. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Herr, P. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Jemth, A.S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; El Andaloussi, S. (Department of Laboratory Medicine. Karolinska Institutet) ; Kalderén, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rodriguez-Perales, S. (Molecular Cytogenetics Group. Human Cancer Genetics Program. Spanish National Cancer Research Centre (CNIO)) ; Benítez, J. (Spanish Network on Rare Diseases (CIBERER)) ; Krokan, H.E. (The Liaison Committee for Education. Research and Innovation in Central Norway) ; Altun, M. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Stenmark, P. (Department of Experimental Medical Science. Lund University) ; Berglund, U.W. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Helleday, T. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
6.
9 p, 1.7 MB Intrinsic functional and architectonic heterogeneity of tumor-targeted protein nanoparticles / Pesarrodona Roches, Mireia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Crosas, Eva (ALBA Laboratori de Llum de Sincrotró) ; Cubarsi, Rafael (Universitat Politècnica de Catalunya. Departament de Matemàtiques) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Saccardo, Paolo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Unzueta Elorza, Ugutz (nstitut d'Investigació Biomèdica Sant Pau) ; Rueda, Fabian (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sánchez García, Laura (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Serna Romero, Naroa (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mangues, Ramon (Institut d'Investigació Biomèdica Sant Pau) ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona
Self-assembling proteins are gaining attention as building blocks for application-tailored nanoscale materials. This is mostly due to the biocompatibility, biodegradability, and functional versatility of peptide chains. [...]
2017 - 10.1039/c6nr09182b
Nanoscale, Vol. 9, issue 19 (May 2017) , p. 6427-6435  
7.
13 p, 1.1 MB Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity / Sant'Anna, Ricardo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gallego Alonso, Pablo (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Robinson, Lei Z. (Scripps Research Institute) ; Pereira-Henriques, Alda (Instituto de Ciências Biomédicas de Abel Salazar) ; Ferreira, Nelson (Instituto de Ciências Biomédicas de Abel Salazar) ; Pinheiro, Francisca (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Esperante, Sebastián (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pallarès i Goitiz, Irantzu (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Huertas, Oscar (SOM-Biotech) ; Almeida, Maria Rosário (Instituto de Ciências Biomédicas de Abel Salazar) ; Reixach, Natàlia (Scripps Research Institute) ; Insa, Raul (SOM-Biotech) ; Velazquez-Campoy, Adrián (Universidad de Zaragoza. Departamento de Bioquímica y Biología Celular y Molecular) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Reig, Núria (SOM-Biotech) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggregation. Native state stabilizers are promising drugs to treat TTR amyloidoses. [...]
2016 - 10.1038/ncomms10787
Nature communications, Vol. 7 (2016) , art. 10787  
8.
10 p, 1.9 MB Studying the complex expression dependences between sets of coexpressed genes / Huerta Casado, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casanova, Oriol (Universitat Autònoma de Barcelona. Escola Tècnica Superior d'Enginyeria) ; Barchino, Roberto (Universitat Autònoma de Barcelona. Escola Tècnica Superior d'Enginyeria) ; Flores, José (Universitat Autònoma de Barcelona. Escola Tècnica Superior d'Enginyeria) ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología)
Organisms simplify the orchestration of gene expression by coregulating genes whose products function together in the cell. The use of clustering methods to obtain sets of coexpressed genes from expression arrays is very common; nevertheless there are no appropriate tools to studge the expression networks among these sets of coexpressed genes. [...]
2014 - 10.1155/2014/940821
BioMed Research International, Vol. 2014 (2014) , art. 940821  
9.
9 p, 1.1 MB Versatile iron-catechol-based nanoscale coordination polymers with antiretroviral ligand functionalization and their use as efficient carriers in HIV/AIDS therapy / Solórzano Rodríguez, Ruben (Institut Català de Nanociència i Nanotecnologia) ; Tort Regàs, Olívia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Garcia-Pardo, Javier (Institut Català de Nanociència i Nanotecnologia) ; Escribà, Tuixent (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lorenzo Rivera, Julia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Arnedo, Mireia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ruiz-Molina, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Alibés Arqués, Ramon (Universitat Autònoma de Barcelona. Departament de Química) ; Busqué Sánchez, Félix (Universitat Autònoma de Barcelona. Departament de Química) ; Novio Vázquez, Fernando (Institut Català de Nanociència i Nanotecnologia)
A novel chemical approach integrating the benefits of nanoparticles with versatility of coordination chemistry is reported herein to increase the effectiveness of well-known HIV antiretroviral drugs. [...]
2019 - 10.1039/c8bm01221k
Biomaterials science, Vol. 7, Issue 1 (January 2019) , p. 178-186  
10.
10 p, 1.7 MB Membrane reorganization after photochemical internalization to release transferrin-biofunctionalized polystyrene microparticles / Mora-Espí, I. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Barrios, L. (Leonardo) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ibáñez, Elena. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Soriano Martín, Jorge. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Therapeutic drug carriers can drive their cargo to their target cells. However, an obstacle is usually the entrapment of the drug inside the endolysosomal compartment, which physically impedes its actuation by the impossibility of reaching its molecular site of action. [...]
2018 - 10.1038/s41598-018-35913-3
Scientific reports (Nature Publishing Group), Vol. 8 (January 2018) , art. 17617  

Articles : 16 registres trobats   1 - 10següent  anar al registre:
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