|
1.
|
|
21 p, 2.8 MB |
Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
/
Parra-Perez, Alberto M. (GENYO. Centre for Genomics and Oncological Research: Pfizer. Universidad de Granada) ;
Pérez-Jiménez, Amalia (Universidad de Granada. Departamento de Zoología. Facultad de Ciencias) ;
Gris-Cárdenas, Isabel (CIC bioGUNE. Centre for Cooperative Research in Biosciences) ;
Bonel-Pérez, Gloria C. (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
Carrasco-Díaz, Luis Miguel (Institut d'Investigació Biomèdica Sant Pau) ;
Mokhtari, khalida (Mohammed I University. Laboratory of Bioresources. Biotechnologies. Ethnopharmacology and Health. Department of Biology. Faculty of Sciences) ;
García-Salguero, Encarnacion Leticia (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ;
Lupiáñez, José Antonio (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ;
Rufino-Palomares, Eva E. (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ;
Universitat Autònoma de Barcelona
Hydroxytyrosol (HT), the main representative of polyphenols of olive oil, has been described as one of the most powerful natural antioxidants, also showing anti-inflammatory, antimicrobial, cardioprotective and anticancer activity in different type of cancers, but has been little studied in hematological neoplasms. [...]
2022 -  10.3390/ijms23137053
International journal of molecular sciences, Vol. 23 Núm. 13 (july 2022) , p. 7053
|
|
|
2.
|
|
12 p, 3.7 MB |
Fetal Tracheal Occlusion Increases Lung Basal Cells via Increased Yap Signaling
/
Serapiglia, Vincent (Northeast Ohio Medical University) ;
Stephens, Chad A. (University of Illinois at Chicago) ;
Joshi, Rashika (Cincinnati Children's Hospital Medical Center) ;
Aydin, Emrah (Cincinnati Children's Hospital Medical Center) ;
Oria Alonso, Marc (University of Cincinnati) ;
Marotta, Mario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Peiro, Jose L. (University of Cincinnati) ;
Varisco, Brian M. (University of Cincinnati) ;
Universitat Autònoma de Barcelona
Fetal endoscopic tracheal occlusion (FETO) is an emerging surgical therapy for congenital diaphragmatic hernia (CDH). Ovine and rabbit data suggested altered lung epithelial cell populations after tracheal occlusion (TO) with transcriptomic signatures implicating basal cells. [...]
2022 - 10.3389/fped.2021.780166
Frontiers in Pediatrics, Vol. 9 (february 2022)
|
|
|
3.
|
|
11 p, 1.9 MB |
Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma
/
Recasens-Zorzo, Clara (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cardesa-Salzmann, Teresa (Hospital Clínic i Provincial de Barcelona) ;
Petazzi, Paolo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ros-Blanco, Laia (Universitat Ramon Llull. Institut Químic de Sarrià-IQS) ;
Esteve-Arenys, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Clot, Guillem (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Guerrero-Hernández, Martina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rodríguez, Vanina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Soldini, Davide (Hospital Clínic i Provincial de Barcelona) ;
Valera, Alexandra (Hospital Clínic i Provincial de Barcelona) ;
Moros, Alexandra (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Climent, Fina (Hospital Universitari de Bellvitge) ;
Gonzalez-Barca, Eva (Institut Català d'Oncologia) ;
Mercadal, Santiago (Institut Català d'Oncologia) ;
Arenillas, Leonor (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Calvo, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Mate Sanz, Jose Luís (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gutiérrez-García, Gonzalo (Hospital Clínic i Provincial de Barcelona) ;
Casanova Rigat, Isolda (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau) ;
Sanjuan-Pla, Alejandra (Hospital Universitari i Politècnic La Fe (València)) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martínez, Antonio (Hospital Clínic i Provincial de Barcelona) ;
Colomer, Dolors (Hospital Clínic i Provincial de Barcelona) ;
Estrada Tejedor, Roger (Universitat Ramon Llull) ;
Teixidó, Jordi (Universitat Ramon Llull) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
López-Guillermo, A. (Hospital Clínic i Provincial de Barcelona) ;
Borrell, José Ignacio (Universitat Ramon Llull) ;
Colomo, Luis (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Pérez-Galán, Patricia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Roué, Gaël (Vall d'Hebron Institut d'Oncologia) ;
Universitat Autònoma de Barcelona
Constitutive activation of the chemokine receptor CXCR4 has been associated with tumor progression, invasion, and chemotherapy resistance in different cancer subtypes. Although the CXCR4 pathway has recently been suggested as an adverse prognostic marker in diffuse large B-cell lymphoma, its biological relevance in this disease remains underexplored. [...]
2019 - 10.3324/haematol.2017.180505
Haematologica, Vol. 104 Núm. 4 (31 2019) , p. 778-788
|
|
|
4.
|
|
25 p, 4.2 MB |
Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells
/
Tishchenko, Alexander (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Azorín, Daniel D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vidal-Brime, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
José Muñoz, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jiménez Arenas, Pol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pearce, Christopher (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Girao, Henrique (University of Coimbra. Faculty of Medicine) ;
Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Aasen, Trond (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are not fully understood. [...]
2020 - 10.3390/cancers12102798
Cancers, Vol. 12 Núm. 10 (2020) , p. 2798
|
|
|
5.
|
|
26 p, 2.2 MB |
Nanostructured toxins for the selective destruction of drug-resistant human CXCR4+ colorectal cancer stem cells
/
Serna, Naroa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Álamo, Patricia (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Ramesh, Prashanthi (Oncode Institute (Amsterdam, Països Baixos)) ;
Vinokurova, Daria (Oncode Institute (Amsterdam, Països Baixos)) ;
Sánchez-García, Laura (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Unzueta Elorza, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ;
Gallardo, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ;
Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau) ;
Medema, Jan Paul (Oncode Institute (Amsterdam, Països Baixos))
Current therapies fail to eradicate colorectal Cancer Stem Cells (CSCs). One of the proposed reasons for this failure is the selection, by chemotherapy exposure, of resistant cells responsible for tumor recurrence. [...]
2020 - 10.1016/j.jconrel.2020.01.019
Journal of Controlled Release, Vol. 320 (April 2020) , p. 96-104
2 documentos
|
|
|
6.
|
|
|
7.
|
|
11 p, 2.1 MB |
Interplay between ncRNAs and cellular communication : A proposal for understanding cell-specific signaling pathways
/
Ramón y Cajal, Santiago (Centro de Investigación Biomédica en Red de Cáncer) ;
Segura, M. F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hümmer, Stefan (Centro de Investigación Biomédica en Red de Cáncer) ;
Universitat Autònoma de Barcelona
Intercellular communication is essential for the development of specialized cells, tissues, and organs and is critical in a variety of diseases including cancer. Current knowledge states that different cell types communicate by ligand-receptor interactions: hormones, growth factors, and cytokines are released into the extracellular space and act on receptors, which are often expressed in a cell-type-specific manner. [...]
2019 - 10.3389/fgene.2019.00281
Frontiers in genetics, Vol. 10 Núm. APR (2019) , p. 281
|
|
|
8.
|
|
13 p, 6.6 MB |
Myo1F, an unconventional long-tailed myosin, is a new partner for the adaptor 3BP2 involved in mast cell migration
/
Navinés-Ferrer, Arnau (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ainsua-Enrich, Erola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Serrano-Candelas, Eva (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sayós, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martin, Margarita (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
2019 - 10.3389/fimmu.2019.01058
Frontiers in immunology, Vol. 10 Núm. MAY (2019) , p. 1058
|
|
|
9.
|
|
40 p, 2.1 MB |
Ser/Thr protein phosphatases in fungi : structure, regulation and function
/
Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Velázquez, Diego (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Casamayor Gracia, Antonio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Reversible phospho-dephosphorylation of proteins is a major mechanism for the control of cellular functions. By large, Ser and Thr are the most frequently residues phosphorylated in eukaryotes. Removal of phosphate from these amino acids is catalyzed by a large family of well-conserved enzymes, collectively called Ser/Thr protein phosphatases. [...]
2019 - 10.15698/mic2019.05.677
Microbial cell, Vol. 6, issue 5 (May 2019) , p. 217-256
|
|
|
10.
|
|
13 p, 6.0 MB |
Mesenchymal stem cells induce expression of cD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo
/
Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rudilla, F. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Borràs i Serres, Francesc Enric (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti- inflammatory regulation by Ado. [...]
2017 - 10.3389/fimmu.2017.01577
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-13
|
|
visitante ::
identificación
alerta personal vía correo electrónico o subscríbase al 
canal RSS.
