Resultats globals: 17 registres trobats en 0.02 segons.
Articles, 11 registres trobats
Documents de recerca, 6 registres trobats
Articles 11 registres trobats  1 - 10següent  anar al registre:
1.
8 p, 1.4 MB Antitumoral effect of maintained neutrophilia induced by rhG-CSF in a murine model of pancreatic cancer / Brú, A. (Faculty of Mathematics. Universidad Complutense de Madrid) ; Bosch, R. (Institut d'Investigació Biomèdica Sant Pau) ; Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ; Carmona, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Pascual, E. (Institut d'Investigació Biomèdica Sant Pau) ; Brú, I. (Centro de Salud La Estación) ; Souto, J.C. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Although the protumoral functions of polymorphonuclear neutrophils are well known, some now-forgotten studies report antitumoral roles for these cells. The present work examines the antitumoral effect of maintained neutrophilia induced via the injection of recombinant human granulocyte colony stimulating factor (rhG-CSF, 100 μg/kg/day) in a Panc-1 subcutaneous xenograft murine model of pancreatic cancer. [...]
2019 - 10.1038/s41598-019-39805-y
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2879  
2.
18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Department of Biotechnology and Nanomedicine. Sintef Industry) ; Benítez-Buelga, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Cázares-Körner, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Sanjiv, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hanna, B.M.F. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Mortusewicz, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rajagopal, V. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Albers, J.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hagey, D.W. (Department of Laboratory Medicine. Karolinska Institutet) ; Bekkhus, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Eshtad, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Baquero, J.M. (Human Genetics Group. Spanish National Cancer Research Centre (CNIO)) ; Masuyer, G. (Department of Pharmacy and Pharmacology. Centre for Therapeutic Innovation. University of Bath) ; Wallner, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Müller, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pham, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Göktürk, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rasti, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Suman, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Department of Environment and New Resources. Sintef Ocean) ; Wiita, E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Homan, E.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Karsten, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Marimuthu, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Michel, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Koolmeister, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Scobie, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Loseva, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Almlöf, I. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Unterlass, J.E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pettke, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Boström, J. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Pandey, M. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Gad, H. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Herr, P. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Jemth, A.S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; El Andaloussi, S. (Department of Laboratory Medicine. Karolinska Institutet) ; Kalderén, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rodriguez-Perales, S. (Molecular Cytogenetics Group. Human Cancer Genetics Program. Spanish National Cancer Research Centre (CNIO)) ; Benítez, J. (Spanish Network on Rare Diseases (CIBERER)) ; Krokan, H.E. (The Liaison Committee for Education. Research and Innovation in Central Norway) ; Altun, M. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Stenmark, P. (Department of Experimental Medical Science. Lund University) ; Berglund, U.W. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Helleday, T. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
3.
12 p, 548.1 KB Mosaicism in Fanconi anemia : concise review and evaluation of published cases with focus on clinical course of blood count normalization / Nicoletti, Eileen (Rocket Pharmaceuticals, Inc., New York) ; Rao, Gayatri (Rocket Pharmaceuticals, Inc., New York, NY USA) ; Bueren, Juan A. (Instituto de Investigaciones Sanitarias Fundación Jiménez Díaz) ; Río, Paula (Instituto de Investigaciones Sanitarias Fundación Jiménez Díaz) ; Navarro, Susana (Instituto de Investigaciones Sanitarias Fundación Jiménez Díaz) ; Surrallés i Calonge, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Choi, Grace (Rocket Pharmaceuticals, Inc., New York) ; Schwartz, Jonathan D. (Rocket Pharmaceuticals, Inc., New York) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Fanconi anemia (FA) is a DNA repair disorder resulting from mutations in genes encoding for FA DNA repair complex components and is characterized by variable congenital abnormalities, bone marrow failure (BMF), and high incidences of malignancies. [...]
2020 - 10.1007/s00277-020-03954-2
Annals of Hematology, Vol. 99 (february 2020) , p. 913-924  
4.
8 p, 3.4 MB HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells : a two-site study / Grau Vorster, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca ) ; Laitinen, Anita (Finnish Red Cross Blood Service. Advanced Cell Therapy Centre) ; Nystedt, Johanna (Finnish Red Cross Blood Service. Advanced Cell Therapy Centre) ; Vives, Joaquim (Universitat Autònoma de Barcelona. Departament de Medicina) ; Hospital Universitari Vall d'Hebron ; Universitat Autònoma de Barcelona
Background: Contrary to the minimal criteria proposed by the International Society for Cell and Gene Therapy for defining multipotent mesenchymal stromal cells (MSC), human leukocyte antigen (HLA)-DR expression is largely unpredictable in ex vivo-expanded clinical-grade cultures. [...]
2019 - 10.1186/s13287-019-1279-9
Stem cell research & therapy, Vol. 10 Núm. 1 (13 2019) , p. 164  
5.
13 p, 3.0 MB Compliance with good manufacturing practice in the assessment of immunomodulation potential of clinical grade multipotent mesenchymal stromal Cells Derived from Wharton's Jelly / Grau-Vorster, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca ) ; Rodríguez, Luciano (Banc de Sang i Teixits) ; del Mazo-Barbara, Anna (Banc de Sang i Teixits) ; Mirabel, Clémentine (Banc de Sang i Teixits) ; Blanco, Margarita (Banc de Sang i Teixits) ; Codinach i Creus, Margarita (Banc de Sang i Teixits) ; G. Gómez, Susana (Banc de Sang i Teixits) ; Querol, Sergi (Banc de Sang i Teixits) ; García-López, Joan (Banc de Sang i Teixits) ; Vives Armengol, Joaquim (Banc de Sang i Teixits)
The selection of assays suitable for testing the potency of clinical grade multipotent mesenchymal stromal cell (MSC)-based products and its interpretation is a challenge for both developers and regulators. [...]
2019 - 10.3390/cells8050484
Cells, Vol. 8 (2019) , p. 1-13  
6.
6 p, 617.5 KB The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction : rationale and design of the trial / Mathur, Anthony (Queen Mary University of London (UK)) ; Arnold, Roman (Hospital Clínico Universitario de Valladolid) ; Assmus, Birgit (Johann-Wolfgang-Goethe University (Germany)) ; Bartunek, Jozef (VZW Cardiovascular Research Center Aalst (Belgium)) ; Belmans, Ann (KU Leuven-University of Leuven & Universiteit Hasselt (Belgium)) ; Bönig, Halvard (Johann-Wolfgang-Goethe University (Germany)) ; Crea, Filippo (Catholic University of the Sacred Heart (Italy)) ; Dimmeler, Stefanie (Johann-Wolfgang-Goethe University (Germany)) ; Dowlut, Sheik (Queen Mary University of London (UK)) ; Fernández-Avilés, Francisco (Hospital General Universitario Gregorio Marañón) ; Galiñanes, Manuel (Hospital Universitari Vall d'Hebron) ; García Dorado, David (Hospital Universitari Vall d'Hebron) ; Hartikainen, Juha (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Hill, Jonathan (King's College Hospital (UK)) ; Hogardt-Noll, Annette (t2cure (Germany)) ; Homsy, Christian (Celyad SA (Belgium)) ; Janssens, Stefan (University Hospitals Leuven (Belgium)) ; Kala, Petr (Faculty Hospital and Masaryk University (Czech Republic)) ; Kastrup, Jens (Rigshospitalet University of Copenhagen (Denmark)) ; Martin, John (University College London (UK)) ; Menasche, Philippe (University Paris Descartes. Assistance Publique Hopitaux de Paris (France)) ; Miklik, Roman (Faculty Hospital and Masaryk University (Czech Republic)) ; Mozid, Abdul (Barts Heart Centre (UK)) ; San Román, J. Alberto (Hospital Clínico Universitario de Valladolid) ; Sanz-Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ; Tendera, Michal (Medical University of Silesia (Poland)) ; Wojakowski, Wojtek (Medical University of Silesia (Poland)) ; Ylä-Herttuala, Seppo (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Zeiher, Andreas (Johann-Wolfgang-Goethe University (Germany)) ; Universitat Autònoma de Barcelona
Over the past 13 years bone marrow-derived mononuclear cells () have been widely investigated for clinical efficacy in patients following acute myocardial infarction (). These early phase trials have used various surrogate markers to judge efficacy and, although promising, the results have been inconsistent. [...]
2017 - 10.1002/ejhf.829
European Journal of Heart Failure, Vol. 19, Issue 11 (November 2017) , p. 1545-1550  
7.
17 p, 2.3 MB Intracoronary Administration of Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells Improves Myocardial Perfusion But Not Left Ventricle Function, in a Translational Model of Acute Myocardial Infarction / Bobi, Joaquim (Universitat de Barcelona) ; Solanes, Núria (Universitat de Barcelona) ; Fernández-Jiménez, Rodrigo (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Galán-Arriola, Carlos (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Dantas, Ana Paula (Universitat de Barcelona) ; Fernández-Friera, Leticia (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Rigol-Monzó, Elisabet (Hospital Clínic de Barcelona) ; Agüero, Jaume (Hospital Universitari i Politècnic La Fe) ; Ramírez, José (Hospital Clínic de Barcelona) ; Roqué, Mercè (Universitat de Barcelona) ; Bayés Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Sánchez-González, Javier (Philips Healthcare, Madrid) ; García-Álvarez, Ana (Centro Nacional de Investigaciones Cardiovasculares Carlos III, CNIC) ; Sabaté, Manel (Universitat de Barcelona) ; Roura, Santiago (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Ibáñez, Borja (CIBER de enfermedades CardioVasculares (CIBERCV)) ; Rigol, Montserrat (Universitat de Barcelona)
Autologous adipose tissue-derived mesenchymal stem cells (s) therapy is a promising strategy to improve post-myocardial infarction outcomes. In a porcine model of acute myocardial infarction, we studied the long-term effects and the mechanisms involved in allogeneic s administration on myocardial performance. [...]
2017 - 10.1161/JAHA.117.005771
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6 (may 2017)  
8.
7 p, 970.6 KB First-in-man Safety and Efficacy of the Adipose Graft Transposition Procedure (AGTP) in Patients With a Myocardial Scar / Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Gastelurrutia, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cámara, Maria-Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Teis, Albert (Clínica Creu Blanca, Barcelona, Spain) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Llibre, Cinta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Elisabet (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alomar, Xavier (Clínica Creu Blanca, Barcelona, Spain) ; Ruyra, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Center of Regenerative Medicine in Barcelona, Barcelona, Spain) ; Revilla, Ana (ICICORELAB, Clinic University Hospital, Valladolid, Spain) ; San Román, José Alberto (ICICORELAB, Clinic University Hospital, Valladolid, Spain) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The present study evaluates the safety and efficacy of the Adipose Graft Transposition Procedure (AGTP) as a biological regenerative innovation for patients with a chronic myocardial scar. This prospective, randomized single-center controlled study included 10 patients with established chronic transmural myocardial scars. [...]
2016 - 10.1016/j.ebiom.2016.03.027
EBioMedicine, Vol. 7 (april 2016) , p. 248-254  
9.
14 p, 516.6 KB Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies / Lord, Phillip (Newcastle University. School of Computing Science) ; Spiering, Rachel (Newcastle University. Institute of Cellular Medicine) ; Aguillon, Juan C. (Universidad de Chile. Instituto de Ciencias Biomédicas (ICBM)) ; Anderson, Amy E. (Newcastle University. Institute of Cellular Medicine) ; Appel, Silke (University of Bergen. Broegelmann Research Laboratory) ; Benítez Ribas, Daniel (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)) ; Brinke, Anja ten (Sanquin Research (Amsterdam)) ; Broere, Femke (Utrecht University) ; Cools, Nathalie (University of Antwerp. Vaccine & Infectious Disease Institute) ; Cuturi, Maria Cristina (Center for Research in Transplantation and Immunology (Nantes, França)) ; Diboll, Julie (Newcastle University. Institute of Cellular Medicine) ; Geissler, Edward K. (University Hospital Regensburg. Department of Surgery) ; Giannoukakis, Nick (Institute of Cellular Therapeutics (Pittsburgh, Estats Units d'Amèrica)) ; Gregori, Silvia (San Raffaele Telethon Institute for Gene Therapy (Milà, Itàlia)) ; Ham, S. Marieke van (Sanquin Research (Amsterdam)) ; Lattimer, Staci (Newcastle University. School of Computing Science) ; Marshall, Lindsay (Newcastle University. School of Computing Science) ; Harry, Rachel A. (Newcastle University. Institute of Cellular Medicine) ; Hutchinson, James A. (University Hospital Regensburg. Department of Surgery) ; Isaacs, John D. (Newcastle University. Institute of Cellular Medicine) ; Joosten, Irma (Radboud University Medical Centre) ; Kooten, Cees van (Leiden University Medical Centre) ; López Díaz de Cerio, Ascensión (Clínica Universidad de Navarra) ; Nikolic, Tatjana (Leiden University Medical Centre) ; Oral, Haluk Barbaros (Uludag University. Faculty of Medicine) ; Sofronic Milosavljevic, Ljiljana (University of Belgrade. Institute for the Application of Nuclear Energy) ; Ritter, Thomas (National University of Ireland) ; Riquelme, Paloma (University Hospital Regensburg. Department of Surgery) ; Thomson, Angus W. (University of Pittsburgh School of Medicine) ; Trucco, Massimo (Institute of Cellular Therapeutics (Pittsburgh, Estats Units d'Amèrica)) ; Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Hilkens, Catharien M. U. (Newcastle University. Institute of Cellular Medicine)
Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. [...]
2016 - 10.7717/peerj.2300
PeerJ, Vol. 4 (August 2016) , p. e2300  
10.
20 p, 974.0 KB Effects of the post-spinal cord injury microenvironment on the differentiation capacity of human neural stem cells derived from induced pluripotent stem cells / López-Serrano, Clara (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres Espín, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hernández Martín, Joaquim (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Álvarez Palomo, Ana Belén (Universitat de Barcelona) ; Requena, Jordi (Universitat de Barcelona) ; Gasull Casanova, Xavier (Universitat de Barcelona) ; Edel, Michael John (Universitat de Barcelona) ; Navarro, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Spinal cord injury (SCI) causes loss of neural functions below the level of the lesion due to interruption of spinal pathways and secondary neurodegenerative processes. The transplant of neural stem cells (NSCs) is a promising approach for the repair of SCI. [...]
2016 - 10.3727/096368916X691312
Cell transplantation, Vol. 25, núm. 10 (2016) , p. 1833-1852  

Articles : 11 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 6 registres trobats  
1.
1 p, 933.3 KB EGFR in non-small cell lung cancer and its role as a targeted therapy / Serra Pascual, Carla ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Biologia [812]  
2.
1 p, 2.6 MB Applications of the induced pluripotent stem cell technology in neurodegenerative diseases / Matres Rojo, Ana ; Ibáñez, Elena, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
3.
1 p, 1.7 MB Strategies of gene and cell therapy for the epidermolysis bullosa treatment and future perspectives / Martín Rioja, Anna ; Bosch i Merino, Assumpció, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
4.
1 p, 2.3 MB Therapeutic approach design for Duchenne muscular dystrophy : autologous ex vivo cell therapy and in vivo gene therapy / González Ramos, Ana ; Ibáñez, Elena, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
5.
1 p, 11.3 MB Gene therapy for severe combined immunodeficiency disease / Medrano González, Laura ; Surrallés i Calonge, Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  
6.
1 p, 1023.6 KB Lentiviral vectors : approaches and possible use in bone marrow failure syndrome / Ramos Ochoa, Facundo ; Surrallés i Calonge, Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  

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