Resultats globals: 2 registres trobats en 0.02 segons.
Articles, 2 registres trobats
Articles 2 registres trobats  
1.
8 p, 2.5 MB Protein-Corona-by-Design in 2D : A Reliable Platform to Decode Bio–Nano Interactions for the Next-Generation Quality-by-Design Nanomedicines / Mei, Kuo‐Ching (King's College London) ; Ghazaryan, Artur (Max Planck Institute for Polymer Research) ; Teoh, Er Zhen (King's College London) ; Summers, Huw D. (Swansea University) ; Li, Yueting (Guizhou Medical University) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Piasecka, Justyna (Swansea University) ; Walters, Adam (King's College London) ; Hider, Robert C. (King's College London) ; Mailänder, Volker (Johannes Gutenberg-University. Department of Dermatology) ; Al-Jamal, Khuloud T. (King's College London)
Hard corona (HC) protein, i. e. , the environmental proteins of the biological medium that are bound to a nanosurface, is known to affect the biological fate of a nanomedicine. Due to the size, curvature, and specific surface area (SSA) 3-factor interactions inherited in the traditional 3D nanoparticle, HC-dependent bio–nano interactions are often poorly probed and interpreted. [...]
2018 - 10.1002/adma.201802732
Advanced materials, Vol. 30, Issue 40 (October 2018) , art. 1802732  
2.
70 p, 2.1 MB Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors / Di Pietro, O. (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Alencar, Nelson (Universitat de Barcelona. Facultat de Farmàcia) ; Esteban Conde, Gerard (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Viayna, Elisabet (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Szałaj, Natalia (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Vázquez, Javier (Universitat de Barcelona. Facultat de Farmàcia) ; Juárez-Jiménez, Jordi (Universitat de Barcelona. Facultat de Farmàcia) ; Sola, Irene (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Pérez Fernández, Belén (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Solé Piñol, Montserrat (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Luque Garriga, F. Xavier (Universitat de Barcelona. Facultat de Farmàcia) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Different azides and alkynes have been coupled via Cu-catalyzed 1,3-dipolar Huisgen cycloaddition to afford a novel family of N1- and C5-substituted 1,2,3-triazole derivatives that feature the propargylamine group typical of irreversible MAO-B inhibitors at the C4-side chain of the triazole ring. [...]
2016 - 10.1016/j.bmc.2016.06.045
Bioorganic & medicinal chemistry, Vol. 24 Núm. 20 (October 2016) , p. 4835-4854  

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