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Resultats globals: 11 registres trobats en 0.02 segons.
Articles, 8 registres trobats
Documents de recerca, 3 registres trobats
Articles 8 registres trobats  
1.
38 p, 1.3 MB Aeons of distress : an evolutionary perspective on the bacterial SOS response / Erill, Ivan (Centro Nacional de Microelectrónica (Espanya)) ; Campoy Sánchez, Susana (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Barbé García, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The SOS response of bacteria is a global regulatory network targeted at addressing DNA damage. Governed by the products of the lexA and recA genes, it co-ordinates a comprehensive response against DNA lesions and its description in Escherichia coli has stood for years as a textbook paradigm of stress-response systems in bacteria. [...]
2007 - doi: 10.1111/j.1574-6976.2007.00082.x
FEMS Microbiology Reviews, Vol. 31, issue 6 (Nov. 2007) , p. 637-656  
Registre complet -
2.
17 p, 19.2 MB Alterations in p53, Microsatellite Stability and Lack of MUC5AC Expression as Molecular Features of Colorectal Carcinoma Associated with Inflammatory Bowel Disease / Gené, Míriam (Universitat Autònoma de Barcelona. Departament de Cirurgia) ; Cuatrecasas, Miriam (Hospital Clínic i Provincial de Barcelona) ; Amat, Irene (Complejo Hospitalario de Navarra) ; Veiga, Jesús Alberto (Complejo Hospitalario Universitario de Ferrol) ; Fernández Aceñero, María Jesús (Hospital Clínico San Carlos (Madrid)) ; Fusté Chimisana, Victòria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Tarragona, Jordi (Hospital Arnau de Vilanova (Lleida, Catalunya)) ; Jurado, Ismael (Consorci Sanitari de Terrassa) ; Fernández-Victoria, Rebeca (Hospital Álvaro Cunqueiro (Vigo)) ; Martínez Ciarpaglini, Carolina (Hospital Clínic Universitari (València)) ; Alenda González, Cristina (Hospital General Universitario Dr. Balmis) ; Zac, Carlos (Hospital Universitari i Politècnic La Fe (València)) ; Ortega de la Obra, Pilar (Hospital General de Segovia) ; Fernández-Figueras, María Teresa (Universitat Internacional de Catalunya) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Musulén, Eva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Colitis-associated colorectal carcinoma (CAC) occurs in inflammatory bowel disease (IBD) because of the "chronic inflammation-dysplasia-cancer" carcinogenesis pathway characterized by p53 alterations in the early stages. [...]
2023 - 10.3390/ijms24108655
International journal of molecular sciences, Vol. 24 (may 2023)  
Registre complet - Creative Commons
3.
36 p, 800.8 KB Establishment and validation of surface model for biodosimetry based on γ-H2AX foci detection / López Vásquez, Juan Sebastián (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Pujol Canadell, Mònica (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Puig, Pedro (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Ribas, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ; Carrasco de Fez, Pablo (Institut d'Investigació Biomèdica Sant Pau) ; Armengol Rosell, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Introduction: In the event of a radiation accident detecting γ-H2AX foci is being accepted as fast method for triage and dose assessment. However, due to their disappearance kinetics, published calibrations have been constructed at specific post-irradiation times. [...]
2022 - 10.1080/09553002.2022.1998706
International Journal of Radiation Biology, Vol. 98, Issue 1 (2022) , p. 1-10  
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4.
39 p, 4.0 MB Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells / Martín Flix, Marta (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Terradas, Mariona (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Iliakis, George (University Duisburg-Essen Medical School) ; Tusell Padrós, Laura (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Genescà, Anna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
After irradiation, ATM defective cells accumulate unrepaired double strand breaks (DSBs) for several cell divisions. At the chromosome level, unresolved DSBs appear as chromosome breaks that can be efficiently scored by using telomeric and mFISH probes. [...]
2009 - 10.1002/gcc.20679
Genes Chromosomes and Cancer, Vol. 48, Issue 9 (September 2009) , p. 745-759  
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5.
22 p, 2.4 MB Low dose ionizing radiation effects on the immune system / Lumniczky, Katalin (National Public Health Centre. Department of Radiation Medicine) ; Impens, Nathalie (Belgian Nuclear Research Centre) ; Armengol Rosell, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Candéias, Serge (Université Grenoble-Alpes) ; Georgakilas, Alexandros G. (National Technical University of Athens. Physics Department) ; Hornhardt, Sabine (Federal Office for Radiation Protection) ; Martin, Olga A. (The University of Melbourne. Peter MacCallum Department of Oncology) ; Rödel, Franz (Goethe University Frankfurt am Main. Department of Radiotherapy and Oncology) ; Schaue, Dörthe (University of California at Los Angeles. Department of Radiation Oncology)
Ionizing radiation interacts with the immune system in many ways with a multiplicity that mirrors the complexity of the immune system itself: namely the need to maintain a delicate balance between different compartments, cells and soluble factors that work collectively to protect, maintain, and restore tissue function in the face of severe challenges including radiation damage. [...]
2021 - 10.1016/j.envint.2020.106212
Environment International, Vol. 149 (April 2021) , art. 106212  
Registre complet - Creative Commons
6.
24 p, 6.9 MB VRK1 Phosphorylates Tip60/KAT5 and Is Required for H4K16 Acetylation in Response to DNA Damage / García-González, Raúl (Instituto de Investigación Biomédica de Salamanca) ; Morejón-García, Patricia (Instituto de Investigación Biomédica de Salamanca) ; Campillo-Marcos, Ignacio (Instituto de Investigación Biomédica de Salamanca) ; Salzano, Marcella (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lazo, Pedro A. (Instituto de Investigación Biomédica de Salamanca) ; Universitat Autònoma de Barcelona
Dynamic remodeling of chromatin requires epigenetic modifications of histones. DNA damage induced by doxorubicin causes an increase in histone H4K16ac, a marker of local chromatin relaxation. We studied the role that VRK1, a chromatin kinase activated by DNA damage, plays in this early step. [...]
2020 - 10.3390/cancers12102986
Cancers, Vol. 12 (october 2020)  
Registre complet - Creative Commons
7.
6 p, 1.1 MB A role for the spindle assembly checkpoint in the DNA damage response / Palou, Roger (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Palou Marin, Gloria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Garcia Quintana, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Spontaneous DNA damage poses a continuous threat to genomic integrity. If unchecked, genotoxic insults result in genomic instability, a hallmark of cancer cells. In eukaryotic cells a DNA Damage Response (DDR) detects and responds to genotoxic stress, acting as an anti-cancer barrier in humans. [...]
2016 - 10.1007/s00294-016-0634-y
Current Genetics, Vol. 63, Num. 2 (August 2016) , p. 275-280  
Registre complet - Creative Commons
8.
6 p, 434.9 KB PAR-5 is a PARty hub in the germline / Aristizábal-Corrales, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schwartz Jr, Simo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cerón, Julián (Institut d'Investigació Biomèdica de Bellvitge) ; Universitat Autònoma de Barcelona
As our understanding of how molecular machineries work expands, an increasing number of proteins that appear as regulators of different processes have been identified. These proteins are hubs within and among functional networks. [...]
2013 - 10.4161/worm.21834
Worm, Vol. 2 (january 2013)  
Registre complet - Creative Commons

Documents de recerca 3 registres trobats  
1.
1 p, 1.5 MB Chromatin plasticity in the DNA damage response: a key player in double-strand break repair pathway choice / García Moro, Eva ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Ciències Biomèdiques [832]  
Registre complet - Creative Commons
2.
1 p, 1002.9 KB The role of shelterin in cellular senescense and systemic aging / Chen, Qian ; Genescà, Anna, , dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
Registre complet - Creative Commons
3.
1 p, 567.8 KB The SOS response and the dissemination of antibiotic resistances / López Martín, Mario ; Barbé García, Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Microbiologia [816]  
Registre complet - Creative Commons

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