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Results overview: Found 4 records in 0.02 seconds.
Articles, 4 records found
Articles 4 records found  
1.
16 p, 4.5 MB Mapping the Interface of a GPCR Dimer : A Structural Model of the A Adenosine and D Dopamine Receptor Heteromer / Borroto-Escuela, Dasiel O. (Karolinska Institutet (Estocolm, Suècia) ; Rodriguez, David (Science for Life Laboratory, Stockholm University) ; Romero-Fernandez, Wilber (Uppsala University) ; Kapla, Jon (Uppsala University) ; Jaiteh, Mariama (Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University) ; Ranganathan, Anirudh (Stockholm University) ; Lazarova, Tzvetana (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fuxe, Kjell (Karolinska Institutet (Estocolm, Suècia)) ; Carlsson, Jens (Uppsala University)
The A adenosine (AR) and D dopamine (DR) receptors form oligomers in the cell membrane and allosteric interactions across the AR-DR heteromer represent a target for development of drugs against central nervous system disorders. [...]
2018 - 10.3389/fphar.2018.00829
Frontiers in Pharmacology, Vol. 9 (august 2018)  
Detailed record - Creative Commons
2.
18 p, 1.7 MB Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A-Dopamine D Receptor Heterotetramers and Adenylyl Cyclase / Ferré, Sergi (National Institutes of Health, Baltimore, United States) ; Bonaventura, Jordi (National Institutes of Health, Baltimore, United States) ; Zhu, Wendy (Circuit Therapeutics, Menlo Park, United States) ; Hatcher-Solis, Candice (National Institutes of Health, Baltimore, United States) ; Taura, Jaume (Universitat de Barcelona. Institut de Neurociències) ; Quiroz, César (National Institutes of Health, Baltimore, United States) ; Cai, Ning-Sheng (National Institutes of Health, Baltimore, United States) ; Moreno, Estefanía (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Casadó-Anguera, Verònica (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Kravitz, Alexxai V. (National Institutes of Health, Bethesda, United States) ; Thompson, Kimberly R. (Circuit Therapeutics, Inc., Menlo Park, United States) ; Tomasi, Dardo G. (National Institutes of Health, Rockville, United States) ; Navarro Brugal, Gemma (Universitat de Barcelona. Departament de Bioquímica i Fisiologia) ; Cordomí Montoya, Arnau (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Lluís, Carme (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Dessauer, Carmen W. (University of Texas Health Science Center at Houston, United States) ; Volkow, Nora D. (National Institutes of Health, Rockville, United States) ; Casadó, Vicent (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Ciruela, Francisco (Universitat de Barcelona. Institut de Neurociències) ; Logothetis, Diomedes E. (Northeastern University, Boston, United States) ; Zwilling, Daniel (Circuit Therapeutics, Inc, Menlo Park, United States)
The central adenosine system and adenosine receptors play a fundamental role in the modulation of dopaminergic neurotransmission. This is mostly achieved by the strategic co-localization of different adenosine and dopamine receptor subtypes in the two populations of striatal efferent neurons, striatonigral and striatopallidal, that give rise to the direct and indirect striatal efferent pathways, respectively. [...]
2018 - 10.3389/fphar.2018.00243
Frontiers in Pharmacology, Vol. 9 (april 2018)  
Detailed record - Creative Commons
3.
12 p, 4.7 MB Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration : the role of p25/cyclin-dependent kinase 5 / Paoletti, Paola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Vila, Ingrid (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rifé, Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Alberch i Vié, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ginés, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Altered glutamatergic and dopaminergic signaling has been proposed as contributing to the specific striatal cell death observed in Huntington's disease (HD). However, the precise mechanisms by which mutant huntingtin sensitize striatal cells to dopamine and glutamate inputs remain unclear. [...]
2008 - 10.1523/JNEUROSCI.3237-08.2008
The Journal of neuroscience, Vol. 28 No. 40 (Oct. 2008) , p. 10090-10101  
Detailed record - Creative Commons
4.
27 p, 5.0 MB Cellular distribution of the histamine H3 receptor in the basal ganglia : functional modulation of dopamine and glutamate neurotransmission / González Sepúlveda, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Rosell Vilar, Santi (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hoffmann, Hanne Mette (University of Montpellier II) ; Castillo-Ruiz, Mª del Mar (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mignon, Virginie (Université Paris Descartes) ; Moreno Delgado, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Vignes, Michel (University of Montpellier II) ; Díaz, Jorge (Université Paris Descartes) ; Sabrià i Pau, Josefa (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ortiz de Pablo, Jordi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Histamine H3 receptors (H3R) are widely expressed in the brain where they participate in sleep-wake cycle and cognition among other functions. Despite their high expression in some regions of the basal ganglia, their functional role in this forebrain neural network remains unclear. [...]
2013 - 10.1016/j.baga.2012.12.001
Basal ganglia, Vol. 3 No. 2 (Jul. 2013) , p. 109-121  
Detailed record -

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