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7 p, 553.0 KB |
A multicenter analysis of the role of prophylactic transfusion of blood products in patients with cirrhosis and esophageal varices undergoing endoscopic band ligation
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Blasi, Annabel (Hospital Clínic i Provincial de Barcelona) ;
Machlab, Salvador (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Risco, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Costa-Freixas, Joao Pedro (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Hernández-Cely, Geovanny (Hospital Clínic i Provincial de Barcelona) ;
Horta Sangenís, Diana (Hospital Universitari MútuaTerrassa) ;
Bofill, Alex (Hospital Clínic i Provincial de Barcelona) ;
Ruiz-Ramirez, Pablo (Hospital Universitari MútuaTerrassa) ;
Profitos, Joaquim (Consorci Sanitari de Terrassa) ;
Sanahuja, Josep Marti (Hospital Clínic i Provincial de Barcelona) ;
Fernandez-Simon, Alejandro (Hospital Clínic i Provincial de Barcelona) ;
Vergara, Mercedes (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sánchez-Delgado, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cardenas, Andrés (Hospital Clínic i Provincial de Barcelona)
Prophylactic administration of platelets and fresh frozen plasma (FFP) has been recommended in patients with cirrhosis with low platelets and/or prolonged international normalized ratio (INR) without scientific evidence to support this practice. [...]
2021 -  10.1016/j.jhepr.2021.100363
JHEP Reports, Vol. 3 (september 2021)
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13 p, 1.6 MB |
Refining Kidney Survival in 383 Genetically Characterized Patients With Nephronophthisis
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König, Jens Christian (Department of General Pediatrics, University Children's Hospital Münster) ;
Karsay, Rebeka (Department of General Pediatrics, University Children's Hospital Münster) ;
Gerß, Joachim (Institute of Biostatistics and Clinical Research, University of Münster) ;
Schlingmann, Karl-Peter (Department of General Pediatrics, University Children's Hospital Münster) ;
Dahmer-Heath, Mareike (Department of General Pediatrics, University Children's Hospital Münster) ;
Telgmann, Anna-Katharina (Department of General Pediatrics, University Children's Hospital Münster) ;
Kollmann, Sabine (Department of General Pediatrics, University Children's Hospital Münster) ;
Ariceta Iraola, Gema (Hospital Universitari Vall d'Hebron) ;
Gillion, Valentine (Division of Nephrology, Saint-Luc Academic Hospital, Université Catholique Louvain) ;
Bockenhauer, Detlef (Great Ormond Street Hospital for Children (Londres)) ;
Bertholet-Thomas, Aurélia (Centre de Référence des Maladies Rénales Rares-Néphrogones-Hôpital Femme Mère Enfant, Hospices Civils de Lyon-Filière ORKiD) ;
Mastrangelo, Antonio (Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico) ;
Boyer, Olivia (Hôpital Necker-Enfants Malades, Université de Paris) ;
Lilien, Marc (Department of Pediatric Nephrology, University Medical Center Utrecht) ;
Decramer, Stéphane (Université Toulouse III Paul-Sabatier) ;
Schanstra, Joost. P. (Université Toulouse III Paul-Sabatier) ;
Pohl, Martin (Department of Pediatrics, University Hospital Freiburg) ;
Schild, Raphael (University Medical Center Hamburg-Eppendorf) ;
Weber, Stefanie (University Children's Hospital) ;
Hoefele, Julia (Institut für Humangenetik) ;
Drube, Jens (Departement of Pediatric Nephrology, Medical School Hannover) ;
Cetiner, Metin (Department of Pediatric Nephrology, University of Duisburg-Essen) ;
Hansen, Matthias (Clementine Kinderhospital) ;
Thumfart, Julia (Charité - Universitätsmedizin Berlin) ;
Tönshoff, Burkhard (Department of Pediatrics I, University Children's Hospital Heidelberg) ;
Habbig, Sandra (Department of Pediatric, University of Cologne) ;
Liebau, Max Christoph (University Hospital Cologne and Medical) ;
Bald, Martin (Children's Hospital (Alemanya)) ;
Bergmann, Carsten (Medizinische Genetik Mainz (Alemanya)) ;
Pennekamp, Petra (Department of General Pediatrics, University Children's Hospital Münster) ;
Konrad, Martin (Department of General Pediatrics, University Children's Hospital Münster) ;
Universitat Autònoma de Barcelona
Nephronophthisis (NPH) comprises a group of rare disorders accounting for up to 10% of end-stage kidney disease (ESKD) in children. Prediction of kidney prognosis poses a major challenge. We assessed differences in kidney survival, impact of variant type, and the association of clinical characteristics with declining kidney function. [...]
2022 - 10.1016/j.ekir.2022.05.035
Kidney International Reports, Vol. 7 (june 2022) , p. 2016-2028
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14 p, 2.0 MB |
Combination of late gadolinium enhancement and genotype improves prediction of prognosis in non-ischaemic dilated cardiomyopathy
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Mirelis, Jesús G. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Escobar-Lopez, Luis (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Ochoa, Juan Pablo (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Espinosa, María Ángeles (Hospital General Universitario Gregorio Marañón) ;
Villacorta, Eduardo (Universidad de Salamanca) ;
Navarro Peñalver, Marina (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Casas, Guillem (Hospital Universitari Vall d'Hebron) ;
Mora-Ayestarán, Nerea (Complejo Hospitalario de Navarra) ;
Barriales-Villa, Roberto (Universidade da Coruña) ;
Mogollón-Jiménez, María Victoria (Complejo Hospitalario Universitario de Cáceres) ;
García-Pinilla, José Manuel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
García-Granja, Pablo Elpidio (Hospital Clínico Universitario Valladolid) ;
Climent, Vicente (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Palomino-Doza, Julian (Hospital 12 de Octubre (Madrid)) ;
García-Álvarez, Ana (Hospital Clínic i Provincial de Barcelona) ;
Álvarez-Barredo, María (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Cabrera-Borrego, Eva (Hospital Universitario Virgen de las Nieves (Granada)) ;
Ripoll-Vera, Tomás (Hospital Universitario Son Llatzer & IdISBa) ;
Peña-Peña, María Luisa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Rodríguez-González, Elena (Hospital General Universitario Gregorio Marañón) ;
Gallego-Delgado, María (Gerencia Regional de Salud de Castilla y León (SACYL)) ;
Gonzalez-Carrillo, Josefa (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Fernández-Ávila, Ana (Hospital General Universitario Gregorio Marañón) ;
Rodriguez-Palomares, Jose F (Hospital Universitari Vall d'Hebron) ;
Brugada, Ramon (Hospital Universitari de Girona Doctor Josep Trueta) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dominguez, Fernando (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
García-Pavía, Pablo (Universidad Autónoma de Madrid) ;
Universitat Autònoma de Barcelona
Genotype and left ventricular scar on cardiac magnetic resonance (CMR) are increasingly recognized as risk markers for adverse outcomes in non-ischaemic dilated cardiomyopathy (DCM). We investigated the combined influence of genotype and late gadolinium enhancement (LGE) in assessing prognosis in a large cohort of patients with DCM. [...]
2022 - 10.1002/ejhf.2514
European Journal of Heart Failure, Vol. 24 (may 2022) , p. 1183-1196
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10 p, 1.6 MB |
Mortality prediction enhancement in end-stage renal disease : A machine learning approach
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Macias Toro, Edwar Hernando (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Morell Pérez, Antoni (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Serrano García, Javier 1964- (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
López Vicario, José (Universitat Autònoma de Barcelona. Departament de Telecomunicació i Enginyeria de Sistemes) ;
Ibeas, Jose (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
In this work, we propose to combine massive variables collected during the evolution of patients in end-stage renal disease (ESRD), along with machine learning techniques to improve mortality prediction in ESRD. [...]
2020 - 10.1016/j.imu.2020.100351
Informatics in Medicine Unlocked, Vol. 19 (May 2020) , art. 100351
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10 p, 389.9 KB |
A phase II study of human allogeneic liver-derived progenitor cell therapy for acute-on-chronic liver failure and acute decompensation
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Nevens, Frederik (University Hospitals Leuven (Bèlgica)) ;
Gustot, Thierry (C.U.B. Erasme Hospital) ;
Laterre, Pierre-François (Cliniques Universitaires Saint-Luc) ;
Lasser, Luc L. (CHU Brugmann) ;
Haralampiev, Lyudmil E. (Multiprofile Hospital for Active Treatment (MEDICA), Ruse) ;
Vargas, Victor (Hospital Universitari Vall d'Hebron) ;
Lyubomirova, Desislava (University Multiprofile Hospital for Active Treatment "Georgi Stranski") ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Najimi, Mustapha (Institute of Experimental and Clinical Research, Brussels) ;
Michel, Sébastien (Promethera Biosciences, Mont-Saint-Guibert) ;
Stoykov, Ivaylo (Promethera Biosciences, Mont-Saint-Guibert) ;
Gordillo, Noelia (Promethera Biosciences, Mont-Saint-Guibert) ;
Vainilovich, Yelena (Promethera Biosciences, Mont-Saint-Guibert) ;
Barthel, Virginie (Promethera Biosciences, Mont-Saint-Guibert) ;
Clerget-Chossat, Nathalie (Promethera Biosciences, Mont-Saint-Guibert) ;
Sokal, Etienne M. (Cliniques Universitaires Saint-Luc, UCLouvain, Pediatric Hepatology & Gastroenterology Unit) ;
Universitat Autònoma de Barcelona
Human allogeneic liver-derived progenitor cells (HALPC, HepaStem®; Promethera Biosciences, Mont-Saint-Guibert, Belgium) are an advanced therapy medicinal product that could potentially alleviate systemic inflammation and ameliorate liver function in patients with acute-on-chronic liver failure (ACLF) or acute decompensation of cirrhosis (AD). [...]
2021 - 10.1016/j.jhepr.2021.100291
JHEP Reports, Vol. 3 (april 2021)
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11 p, 1.3 MB |
Genetic Variants Associated with Chronic Kidney Disease in a Spanish Population
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Corredor Mancilla, Zuray Fernanda (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Filho, Miguel Inácio da Silva (German Cancer Research Center) ;
Rodríguez-Ribera, Lara (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Velázquez, Antonia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Catalano, Calogerina (German Cancer Research Center) ;
Hemminki, Kari (German Cancer Research Center) ;
Coll, Elisabet (Fundació Puigvert) ;
Silva, Irene (Fundació Puigvert) ;
Díaz Gómez, Juan Manuel (Fundació Puigvert) ;
Ballarín Castan, José Aurelio (Fundació Puigvert) ;
Vallés Prats, Martí (Hospital Universitari de Girona Doctor Josep Trueta) ;
Calabia, Jordi (Hospital Universitari de Girona Doctor Josep Trueta) ;
Försti, Asta (German Cancer Research Center) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pastor, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Chronic kidney disease (CKD) patients have many affected physiological pathways. Variations in the genes regulating these pathways might affect the incidence and predisposition to this disease. A total of 722 Spanish adults, including 548 patients and 174 controls, were genotyped to better understand the effects of genetic risk loci on the susceptibility to CKD. [...]
2020 - 10.1038/s41598-019-56695-2
Scientific reports, Vol. 10 (January 2020) , art. 144
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13 p, 606.0 KB |
Comparison of the Safety and Tolerance Profile of Micafungin with that of Other Echinocandins and Azoles in Patients with Pre-existing Child-Pugh B or C Liver Disease : A Case-Control Retrospective Study
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Vena, Antonio (Hospital General Universitario Gregorio Marañón) ;
Bouza, Emilio (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Bassetti, Matteo (University of Udine) ;
Menichetti, Francesco (Nuovo Santa Chiara University Hospital) ;
Merelli, Maria (University of Udine) ;
Grau, Santiago (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Fortún, Jesús (Hospital Universitario Ramón y Cajal (Madrid)) ;
Sánchez, María Isabel (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Aguado, José María (Universidad Complutense de Madrid) ;
Merino, Paloma (Hospital Clínico San Carlos (Madrid)) ;
Bonache, Francisco (Hospital General Universitario Gregorio Marañón) ;
Muñoz, Patricia (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM))
To assess the association between exposure to micafungin, other echinocandins, or azoles and the development of short-term liver injury (STLI) or long-term liver injury (LTLI) in patients with Child-Pugh B or C liver disease. [...]
2020 - 10.1007/s40121-020-00282-w
Infectious Diseases and Therapy, Vol. 9 (february 2020) , p. 151-163
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8 p, 744.0 KB |
Effects of long-term cysteamine treatment in patients with cystinosis
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Ariceta Iraola, Gema (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Giordano, Vincenzo (Orphan Europe (Puteaux, France)) ;
Santos, Fernando (Hospital Universitario Central de Asturias)
Cystinosis is a rare autosomal-recessive lysosomal storage disease with high morbidity and mortality. It is caused by mutations in the CTNS gene that encodes the cystine transporter, cystinosin, which leads to lysosomal cystine accumulation. [...]
2017 - 10.1007/s00467-017-3856-4
Pediatric Nephrology, Vol. 34 (december 2017) , p. 571-578
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14 p, 1.2 MB |
Renal replacement therapy in Europe : a summary of the 2012 ERA-EDTA Registry Annual Report
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Pippias, Maria (Universiteit van Amsterdam. Department of Informatics) ;
Stel, Vianda S. (Universiteit van Amsterdam. Department of Informatics) ;
Abad Diez, José Maria (Dirección General de Planificación y Aseguramiento. Gobierno de Aragón) ;
Afentakis, Nikolaos (General Hospital of Athens'G. Gennimatas'. Hellenic Renal Registry, Board of Registry, Coordination and Control of RRT) ;
Herrero-Calvo, Jose Antonio (Registro Madrileño de Enfermos Renales (REMER), Sociedad Madrileña de Nefrología) ;
Arias, Manuel (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Tomilina, Natalia (Moscow City Nephrology Center) ;
Bouzas Caamaño, Encarnación (Oficina de Coordinación de Trasplantes, Servicio Gallego de Salud (SERGAS)) ;
Buturovic-Ponikvar, Jadranka (University Medical Center Ljubljana) ;
Čala, Svjetlana (Croatian Society of Nephrology, Dialysis and Transplantation, Zagreb) ;
Caskey, Fergus (School of Social Medicine, Canynge Hall, University of Bristol) ;
Castro de la Nuez, Pablo (Sistema de Información de la Coordinación Autonómica de Trasplantes de Andalucía) ;
Cernevskis, Harijs (Riga Stradins University) ;
Collart, Frederic (French-Belgian ESRD Registry) ;
Alonso de la Torre, Ramón (Public Health Directorate) ;
García Bazaga, María de los Ángeles (Servicio Extremeño de Salud. Consejería de Salud y Política Social) ;
De Meester, Johan (Dutch-speaking Belgian Renal Registry (NBVN)) ;
Díaz Gómez, Juan Manuel (Institut d'Investigació Biomèdica Sant Pau) ;
Djukanovic, Ljubica (School of Medicine, University of Belgrade) ;
Ferrer-Alamar, Manuel (Registro de Enfermos Renales Comunitat Valenciana) ;
Finne, Patrik (Finnish Registry for Kidney Diseases, Helsinki) ;
Garneata, Liliana ('Dr Carol Davila' Teaching Hospital of Nephrology) ;
Golan, Eliezer (Meir Medical Center, Kfar-Saba and Sackler Faculty of Medicine) ;
González Fernández, Raquel (Coordinación Autonómica de Trasplantes de Castilla y León) ;
Gutiérrez Avila, Gonzalo (Registro de Enfermos Renales en Tratamiento Sustitutivo de Castilla-La Mancha) ;
Heaf, James G. (University of Copenhagen) ;
Hoitsma, Andries (Radboud University Medical Center) ;
Kantaria, Nino (Tbilisi State Medical University) ;
Kolesnyk, Mykola (URDS) ;
Kramar, Reinhard (Austrian Dialysis and Transplant Registry) ;
Kramer, Anneke (Universiteit van Amsterdam. Department of Informatics) ;
Lassalle, Mathilde (REIN Registry, Agence de la Biomédecine) ;
Leivestad, Torbjørn (Oslo University Hospital (Oslo, Noruega)) ;
Lopot, Frantisek (Charles University. Department of Medicine) ;
Macario, Fernando (Centro Hospitalar e Universitário de Coimbra (Coimbra, Portugal)) ;
Magaz, Ángela (Comunidad Autónoma del País Vasco. Unidad de Información Sobre Pacientes Renales) ;
Martín-Escobar, Eduardo (Registro Español de Enfermos Renales (REER)) ;
Metcalfe, Wendy (The Scottish Renal Registry, Meridian Court) ;
Noordzij, Marlies (Universiteit van Amsterdam. Department of Informatics) ;
Palsson, Runolfur (University of Iceland. School of Health Sciences) ;
Pechter, Ülle (Tartu University) ;
Prütz, Karl G. (Hospital of Helsingborg) ;
Ratkovic, Marina (Clinical Center of Montenegro) ;
Resić, Halima (University of Sarajevo) ;
Rutkowski, Boleslaw (Medical University) ;
Santiuste de Pablos, Carmen (Registro de Enfermos Renales de la Región de Murcia) ;
Spustová, Viera (Slovak Medical University) ;
Süleymanlar, Gültekin (Istanbul University) ;
Van Stralen, Karlijn (Universiteit van Amsterdam. Department of Informatics) ;
Thereska, Nestor (University Hospital Center, 'Mother Tereza') ;
Wanner, Christoph (University of Würzburg) ;
Jager, Kitty J. (Universiteit van Amsterdam. Department of Informatics) ;
Universitat Autònoma de Barcelona
This article summarizes the 2012 European Renal Association-European Dialysis and Transplant Association Registry Annual Report (available at ) with a specific focus on older patients (defined as ≥65 years). [...]
2015 - 10.1093/ckj/sfv014
Clinical Kidney Journal, Vol. 8 (march 2015) , p. 248-261
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