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8 p, 3.0 MB |
Association of Serum Ferritin Levels Before Start of Conditioning With Mortality After alloSCT - A Prospective, Non-interventional Study of the EBMT Transplant Complications Working Party
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Penack, Olaf (Charité - Universitätsmedizin Berlin) ;
Peczynski, Christophe (EBMT Statistical Unit) ;
van der Werf, Steffie (EBMT Data Office) ;
Finke, Jürgen (University of Freiburg) ;
Ganser, Arnold (Hannover Medical School) ;
Schoemans, Helene (University Hospitals Leuven (Bèlgica)) ;
Pavlu, Jiri (Imperial College London) ;
Niittyvuopio, Riitta (HUCH Comprehensive Cancer Center) ;
Schroyens, W.ilfried (University Hospital Antwerp (Bèlgica)) ;
Kaynar, Leylagül (Erciyes University) ;
Blau, Igor W. (Department of Hematology. Oncology. and Tumor Immunology) ;
van der Velden, Walter J.F.M. (Radboud University) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Cortelezzi, Agostini (University of Milan) ;
Wulf, Gerald (Universitätsklinikum Göttingen) ;
Turlure, Pascal (CHRU Limoges) ;
Rovira Argelagués, Montserrat (Hospital Clínic i Provincial de Barcelona) ;
Ozkurt, Zubeydenur (Gazi University) ;
Pascual-Cascon, Maria J. (Hospital Regional Universitario de Málaga) ;
Moreira, Maria C. (Instituto National do Cancer) ;
Clausen, Johannes (Ordensklinikum Linz Elisabethinen) ;
Greinix, Hildegard (Medical University of Graz) ;
Duarte, Rafael F. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Basak, Grzegorz (Medical University of Warsaw) ;
Universitat Autònoma de Barcelona
Elevated serum ferritin levels occur due to iron overload or during inflammation and macrophage activation. A correlation of high serum ferritin levels with increased mortality after alloSCT has been suggested by several retrospective analyses as well as by two smaller prospective studies. [...]
2020 -  10.3389/fimmu.2020.00586
Frontiers in immunology, Vol. 11 (15 2020) , p. 586
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14 p, 1.2 MB |
Genetic and Clinical Heterogeneity in Thirteen New Cases with Aceruloplasminemia. Atypical Anemia as a Clue for an Early Diagnosis
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Vila Cuenca, Marc (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Marchi, Giacomo (Azienda Ospedaliera Universitaria Integrata di Verona) ;
Barqué, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Esteban-Jurado, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Marchetto, Alessandro (University of Verona) ;
Giorgetti, Alejandro (Department of Biotechnology, University of Verona) ;
Chelban, Viorica (National Hospital for Neurology and Neurosurgery, London) ;
Houlden, Henry (National Hospital for Neurology and Neurosurgery, London) ;
Wood, Nicholas W.. (National Hospital for Neurology and Neurosurgery, London) ;
Piubelli, Chiara (Centre for Tropical Diseases, Ospedale Sacro Cuore - Don Calabria) ;
Dorigatti Borges, Marina (University of Campinas-UNICAMP) ;
Martins de Albuquerque, Dulcinéia (University of Campinas-UNICAMP) ;
Yotsumoto Fertrin, Kleber (University of Campinas-UNICAMP) ;
Jové-Buxeda, Ester (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Sánchez-Delgado, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Baena Díez, Neus (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Burnyte, Birute (Vilnius University) ;
Utkus, Algirdas (Vilnius University) ;
Busti, Fabiana (Azienda Ospedaliera Universitaria Integrata di Verona) ;
Kaubrys, Gintaras (Vilnius University) ;
Suku, Eda (University of Verona) ;
Kowalczyk, Kamil (Medical University of Gdańsk) ;
Karaszewski, Bartosz (Medical University of Gdańsk) ;
Porter, John B. (University College London NHS Foundation Trust) ;
Pollard, Sally (Consultant Paediatrician, Bradford Royal Infirmary) ;
Eleftheriou, Perla (University College London NHS Foundation Trust) ;
Bignell, Patricia (Oxford University Hospitals NHS Foundation Trust) ;
Girelli, Domenico (Azienda Ospedaliera Universitaria Integrata di Verona) ;
Sánchez-Fernández, Mayka (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation in pancreas, retina, liver, and brain. [...]
2020 - 10.3390/ijms21072374
International journal of molecular sciences, Vol. 21 (march 2020)
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14 p, 1.9 MB |
Plasma Levels of Mid-Regional Proadrenomedullin Accurately Identify H1N1pdm09 Influenza Virus Patients with Risk of Intensive Care Admission and Mortality in the Emergency Department
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Valenzuela-Méndez, Blanca (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Valenzuela-Sánchez, Francisco (Hospital Universitario de Jerez (Jerez de la Frontera)) ;
Rodríguez-Gutiérrez, Juan Francisco (Hospital Universitario de Jerez (Jerez de la Frontera)) ;
Bohollo-de-Austria, Rafael (Hospital Universitario de Jerez (Jerez de la Frontera)) ;
Estella, Ángel (Universidad de Cádiz) ;
Martínez-García, Pilar (Hospital Universitario Puerto Real (Cadis)) ;
González-García, María Ángela (Hospital Universitario de Jerez (Jerez de la Frontera)) ;
Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Early identification of severe viral pneumonia in influenza virus A (H1N1pdm09) patients is extremely important for prompt admission to the ICU. The objective is to evaluate the usefulness of MR-proadrenomedullin (MR-proADM) compared to C reactive protein (CRP), procalcitonin (PCT), and ferritin in the prognosis of influenza A pneumonia. [...]
2022 - 10.3390/jpm12010084
Journal of personalized medicine, Vol. 12 (january 2022)
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15 p, 1.5 MB |
Room-temperature tunnel magnetoresistance across biomolecular tunnel junctions based on ferritin
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Karuppannan, Senthil kumar (National University of Singapore. Department of Chemistry) ;
Pasula, Rupali Reddy (Nanyang Technological University. School of Chemical and Biomedical Engineering) ;
Herng, Tun Seng (National University of Singapore. Department of Materials Science and Engineering) ;
Ding, Jun (National University of Singapore. Department of Materials Science and Engineering) ;
Chi, Xiao (Singapore Synchrotron Light Source) ;
Del Barco, Enrique (University of Central Florida. Department of Physics) ;
Roche, Stephan (Institut Català de Nanociència i Nanotecnologia) ;
Yu, Xiaojiang (Singapore Synchrotron Light Source) ;
Yakovlev, Nikolai (Institute of Materials Research and Engineering (Singapur, Singapur)) ;
Lim, Sierin (Nanyang Technological University. School of Chemical and Biomedical Engineering) ;
Nijhuis, Christian A. (University of Twente. Department of Molecules and Materials)
We report exceptionally large tunnel magnetoresistance (TMR) for biomolecular tunnel junctions based on ferritins immobilized between Ni and EGaIn electrodes. Ferritin stores iron in the form of ferrihydrite nanoparticles (NPs) and fulfills the following roles: (a) it dictates the tunnel barrier, (b) it magnetically decouples the NPs from the ferromagnetic (FM) electrode, (c) it stabilizes the NPs, and (d) it acts as a spin filter reducing the complexity of the tunnel junctions since only one FM electrode is required. [...]
2021 - 10.1088/2515-7639/abfa79
JPhys materials, Vol. 4, issue 3 (April 2021) , art. 035003
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15 p, 1.8 MB |
L-ferritin : One gene, five diseases; from hereditary hyperferritinemia to hypoferritinemia-report of new cases
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Cadenas, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Fita-Torró, Josep (BloodGenetics SL. Esplugues de Llobregat) ;
Bermúdez-Cortés, Mar (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Hernandez-Rodriguez, Inés (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, José Luis (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Llinares, María Esther (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Galera, Ana (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Romero, Julia Lee (Biomedical Engineering Department. University of Texas at Austin) ;
Pérez-Montero, Santiago (BloodGenetics SL. Esplugues de Llobregat) ;
Tornador, Cristian (BloodGenetics SL. Esplugues de Llobregat) ;
Sánchez-Fernández, Mayka (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Ferritin is a multimeric protein composed of light (L-ferritin) and heavy (H-ferritin) subunits that binds and stores iron inside the cell. A variety of mutations have been reported in the L-ferritin subunit gene (FTL gene) that cause the following five diseases: (1) hereditary hyperferritinemia with cataract syndrome (HHCS), (2) neuroferritinopathy, a subtype of neurodegeneration with brain iron accumulation (NBIA), (3) benign hyperferritinemia, (4) L-ferritin deficiency with autosomal dominant inheritance, and (5) L-ferritin deficiency with autosomal recessive inheritance. [...]
2019 - 10.3390/ph12010017
Pharmaceuticals, Vol. 12 Núm. 1 (2019) , p. 17
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15 p, 638.1 KB |
A model based on the combination of ifn-γ, ip-10, ferritin and 25-hydroxyvitamin d for discriminating latent from active tuberculosis in children
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Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abellana, Rosa (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ;
Villar-Hernández, Raquel (Institut Germans Trias i Pujol) ;
Coute, M. D. J. (Saint-Damien Pediatric Hospital) ;
Mingels, B. S. (Radiology and Imaging Diagnose Department. Manso Primary Care Center) ;
Canales-Aliaga, Lydia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Narcisse, M. (Saint-Damien Pediatric Hospital) ;
Gautier, Jacqueline (Saint-Damien Pediatric Hospital) ;
Ascaso, C. (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ;
Latorre, Irene (Institut Germans Trias i Pujol) ;
Domínguez, J.. (Institut Germans Trias i Pujol) ;
Pérez-Porcuna, Tomás M. (Universitat de Barcelona. Hospital Mútua de Terrassa) ;
Universitat Autònoma de Barcelona
In recent years, pediatric research on tuberculosis (TB) has focused on addressing new biomarkers with the potential to be used as immunological non-sputum-based methods for the diagnosis of TB in children. [...]
2019 - 10.3389/fmicb.2019.01855
Frontiers in microbiology, Vol. 10 Núm. AUG (2019) , p. 1855
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8 p, 333.4 KB |
Biological signatures of brain damage associated with high serum ferritin levels in patients with acute ischemic stroke and thrombolytic treatment
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Millán, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sobrino, Tomás ;
Arenillas, Juan F.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez-Yáñez, Manuel ;
García, María ;
Nombela, Florentino ;
Castellanos, María del Mar ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cuadras, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background and purpose : Increased body iron stores have been related to greater oxidative stress and brain injury in clinical and experimental cerebral ischemia and reperfusion. We aimed to investigate the biological signatures of excitotoxicity, inflammation and blood brain barrier disruption potentially associated with high serum ferritin levels-related damage in acute stroke patients treated with i. [...]
2008 - 10.1155/2008/380356
Disease markers, Vol. 25 (12 2008) , p. 181-188
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13 p, 2.9 MB |
L-Ferritin Binding to Scara5 : A New Iron Traffic Pathway Potentially Implicated in Retinopathy
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Mendes, Luisa (Universidade de Lisboa. Faculty of Veterinary Medicine) ;
Ramos González, David (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Valença, Andreia (Universidade de Lisboa. Faculty of Veterinary Medicine) ;
López-Luppo, Mariana (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Rico Pires, Virgínia Maria (Universidade de Lisboa. Faculty of Veterinary Medicine) ;
Catita, Joana (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Nacher García, Víctor (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Navarro Beltrán, Marc (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Carretero i Romay, Ana (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ;
Rodríguez Baeza, Alfonso (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Ruberte, Jesús (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG))
Iron is essential in the retina because the heme-containing enzyme guanylate cyclase modulates phototransduction in rods and cones. Transferrin endocytosis is the classical pathway for obtaining iron from the blood circulation in the retina. [...]
2014 - 10.1371/journal.pone.0106974
PloS one, Vol. 9, Issue 9 (September 2014) , p.e106974
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