Resultats globals: 2 registres trobats en 0.02 segons.
Articles, 2 registres trobats
Articles 2 registres trobats  
1.
24 p, 14.0 MB Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor : Morphine and Fentanyl Elicit Different Activation Patterns / Ricarte, Adrián (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dalton, James A. R.. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
Over the past two decades, the opioid epidemic in the United States and Canada has evidenced the need for a better understanding of the molecular mechanisms of medications used to fight pain. Morphine and fentanyl are widely used in opiate-mediated analgesia for the treatment of chronic pain. [...]
2021 - 10.1021/acs.jcim.0c00890
Journal of Chemical Information and Modeling, Vol. 61 Núm. 3 (22 2021) , p. 1251-1274
2 documents
2.
42 p, 2.6 MB Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity / Smit, Martine J. (Vrije Universiteit Amsterdam) ; Vischer, Henry F. (Vrije Universiteit Amsterdam) ; Bakker, Remko A. (Vrije Universiteit Amsterdam) ; Jongejan, Aldo (Vrije Universiteit Amsterdam) ; Timmerman, Henk (Vrije Universiteit Amsterdam) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Leurs, Rob (Vrije Universiteit Amsterdam)
G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules. The notion that GPCRs also signal without an external chemical trigger, i. e. in a constitutive or spontaneous manner, resulted in a paradigm shift in the field of GPCR pharmacology. [...]
2007 - 10.1146/annurev.pharmtox.47.120505.105126
The Annual Review of Pharmacology and Toxicology, Vol. 47, Núm. (2007) , p. 53-87  

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