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Articles 76 registres trobats  1 - 10següentfinal  anar al registre:
1.
12 p, 3.6 MB DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load / Jung, H. (Department of Bio and Brain Engineering. KAIST) ; Kim, H.S. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Kim, J.Y. (Department of Bio and Brain Engineering. KAIST) ; Sun, J.M. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Ahn, J.S. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Ahn, M.J. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Park, K. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Lee, S.H. (Department of Health Sciences and Technology. Samsung Advanced Institute of Health Science and Technology. Sungkyunkwan University) ; Choi, J.K. (Penta Medix Co.. Ltd.) ; Universitat Autònoma de Barcelona
Mitotic cell division increases tumour mutation burden and copy number load, predictive markers of the clinical benefit of immunotherapy. Cell division correlates also with genomic demethylation involving methylation loss in late-replicating partial methylation domains. [...]
2019 - 10.1038/s41467-019-12159-9
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 4278  
2.
14 p, 2.0 MB Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bywater, M.J. (QIMR Berghofer Medical Research Institute) ; Sanij, E. (Department of Pathology. University of Melbourne) ; Cameron, D.P. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Schierding, W. (Liggins Institute. The University of Auckland) ; Brajanovski, N. (Cancer Research Division. Peter MacCallum Cancer Centre) ; Son, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Sornkom, J. (Sir Peter MacCallum Department of Oncology. University of Melbourne) ; Hein, N. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Evers, M. (ACRF Department of Cancer Biology and Therapeutics. John Curtin School of Medical Research. Australian National University) ; Pearson, R.B. (Department of Biochemistry and Molecular Biology. University of Melbourne) ; McArthur, G.A. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Ganley, A.R.D. (School of Biological Sciences. The University of Auckland) ; O'Sullivan, J.M. (Liggins Institute. The University of Auckland) ; Hannan, R.D. (School of Biomedical Sciences. University of Queensland) ; Poortinga, G. (Department of Medicine. St Vincent's Hospital. University of Melbourne) ; Universitat Autònoma de Barcelona
The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain unclear. [...]
2019 - 10.1038/s42003-019-0284-y
Communications Biology, Vol. 2 Núm. 1 (january 2019) , p. 39  
3.
13 p, 4.7 MB Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis / Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rogers, R.B. (Department of Medicine. University of Cambridge. Cambridge Biomedical Campus) ; Roy, A. (Department of Paediatrics. University of Oxford) ; Schneider, P. (Princess Maxima Center for Pediatric Oncology) ; Bardini, M. (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ; Ballerini, P. (Pediatric Hematology. A. Trousseau Hospital) ; Cazzaniga, G. (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ; Moreno, T. (Instituto de Biomedicina y Biotecnologia de Cantabria (IBBTEC). Universidad de Cantabria-CSIC) ; Revilla, C. (Instituto de Biomedicina y Biotecnologia de Cantabria (IBBTEC). Universidad de Cantabria-CSIC) ; Gut, M. (Universitat Pompeu Fabra) ; Valsecchi, M.G. (Interfant Trial Data Center. University of Milano-Bicocca) ; Roberts, I. (MRC Molecular Haematology Unit. MRC Weatherall Institute of Molecular Medicine. University of Oxford) ; Pieters, R. (Princess Maxima Center for Pediatric Oncology) ; De Lorenzo, P. (Interfant Trial Data Center. University of Milano-Bicocca) ; Varela, I. (Instituto de Biomedicina y Biotecnologia de Cantabria (IBBTEC). Universidad de Cantabria-CSIC) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Stam, R.W. (Princess Maxima Center for Pediatric Oncology) ; Universitat Autònoma de Barcelona
Bcell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1 (MLL-AF4) infant B-cell acute lymphoblastic leukemia remains difficult to model, and the pathogenic contribution in cancer of the reciprocal fusions resulting from derivative translocated-chromosomes remains obscure. [...]
2019 - 10.3324/haematol.2018.206375
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1176-1188  
4.
7 p, 979.5 KB Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer / Piqué, L. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Martinez de Paz, A. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Piñeyro, D. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Martínez Cardús, Anna (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Castro de Moura, M. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Llinàs-Arias, P. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Setien, F. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Gomez-Miragaya, J. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Gonzalez-Suarez, E. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Sigurdsson, S. (Department of Biochemistry and Molecular Biology. Biomedical Center) ; Jonasson, J.G. (Department of Pathology. Landspitali University Hospital) ; Villanueva, A. (Institut Català d'Oncologia) ; Vidal, A. (Department of Pathology. Bellvitge University Hospital) ; Davalos, V. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Research Institute (IDIBELL). L'Hospitalet) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Human tumors show altered patterns of protein isoforms that can be related to the dysregulation of messenger RNA alternative splicing also observed in transformed cells. Although somatic mutations in core spliceosome components and their associated factors have been described in some cases, almost nothing is known about the contribution of distorted epigenetic patterns to aberrant splicing. [...]
2019 - 10.1038/s41388-019-0936-x
Oncogene, Vol. 38 Núm. 45 (july 2019) , p. 7106-7112  
5.
16 p, 1.4 MB A Shorter Equilibration Period Improves Post-Warming Outcomes after Vitrification and in Straw Dilution of In Vitro-Produced Bovine Embryos / Martínez-Rodero, Iris (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Ordóñez-León, Erika Alina (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Vendrell i Flotats, Meritxell (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Olegario Hidalgo, Carlos (Servei Regional de Recerca i Desenvolupament Agroalimentari d'Astúries. Departament de selecció i reproducció d'animals) ; Esmoris, Joseba (Aliança Basca de Recerca i Tecnologia (BRTA)) ; Mendibil, Xabier (Aliança Basca de Recerca i Tecnologia (BRTA)) ; Azcarate, Sabino (Aliança Basca de Recerca i Tecnologia (BRTA)) ; López Béjar, Manel (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ; Yeste Oliveras, Marc (Universitat de Girona. Departament de Biologia) ; Mogas Amorós, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; García-Martínez, Tania (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
This study was designed to the optimize vitrification and in-straw warming protocol of in vitro-produced bovine embryos by comparing two different equilibration periods, short equilibrium (SE: 3 min) and long equilibrium (LE: 12 min). [...]
2021 - 10.3390/biology10020142
Biology, Vol. 10 Núm. 2 (2021) , p. 142  
6.
15 p, 2.9 MB MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer / Mattesen, T.B. (Department of Molecular Medicine. Aarhus University Hospital) ; Rasmussen, M.H. (Department of Molecular Medicine. Aarhus University Hospital) ; Sandoval, J. (Biomarker and precision medicine Unit. Health Research Institute La Fe (ISSLaFe)) ; Ongen, H. (Genetic Medicine and Development. University of Geneva Medical School-CMU) ; Árnadóttir, S.S. (Department of Molecular Medicine. Aarhus University Hospital) ; Gladov, J. (Department of Molecular Medicine. Aarhus University Hospital) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol) ; Castro de Moura, Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Madsen, A.H. (Department of Surgery. Hospitalsenheden Vest) ; Laurberg, S. (Colorectal Surgical Unit. Department of Surgery. Aarhus University Hospital) ; Dermitzakis, E.T. (Genetic Medicine and Development. University of Geneva Medical School-CMU) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Andersen, C.L. (Department of Molecular Medicine. Aarhus University Hospital) ; Bramsen, J.B. (Department of Molecular Medicine. Aarhus University Hospital) ; Universitat Autònoma de Barcelona
Transcriptional characterization and classification has potential to resolve the inter-tumor heterogeneity of colorectal cancer and improve patient management. Yet, robust transcriptional profiling is difficult using formalin-fixed, paraffin-embedded (FFPE) samples, which complicates testing in clinical and archival material. [...]
2020 - 10.1038/s41467-020-16000-6
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 2025  
7.
18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Department of Biotechnology and Nanomedicine. Sintef Industry) ; Benítez-Buelga, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Cázares-Körner, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Sanjiv, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hanna, B.M.F. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Mortusewicz, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rajagopal, V. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Albers, J.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hagey, D.W. (Department of Laboratory Medicine. Karolinska Institutet) ; Bekkhus, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Eshtad, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Baquero, J.M. (Human Genetics Group. Spanish National Cancer Research Centre (CNIO)) ; Masuyer, G. (Department of Pharmacy and Pharmacology. Centre for Therapeutic Innovation. University of Bath) ; Wallner, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Müller, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pham, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Göktürk, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rasti, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Suman, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Department of Environment and New Resources. Sintef Ocean) ; Wiita, E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Homan, E.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Karsten, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Marimuthu, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Michel, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Koolmeister, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Scobie, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Loseva, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Almlöf, I. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Unterlass, J.E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pettke, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Boström, J. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Pandey, M. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Gad, H. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Herr, P. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Jemth, A.S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; El Andaloussi, S. (Department of Laboratory Medicine. Karolinska Institutet) ; Kalderén, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rodriguez-Perales, S. (Molecular Cytogenetics Group. Human Cancer Genetics Program. Spanish National Cancer Research Centre (CNIO)) ; Benítez, J. (Spanish Network on Rare Diseases (CIBERER)) ; Krokan, H.E. (The Liaison Committee for Education. Research and Innovation in Central Norway) ; Altun, M. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Stenmark, P. (Department of Experimental Medical Science. Lund University) ; Berglund, U.W. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Helleday, T. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
8.
17 p, 5.7 MB An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells / Colli, M.L. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Ramos-Rodríguez, M. (Endocrine Regulatory Genomics Laboratory. Germans Trias i Pujol University Hospital and Research Institute) ; Nakayasu, E.S. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Alvelos, M.I. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Lopes, M. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Hill, J.L.E. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Turatsinze, J.V. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Coomans de Brachène, A. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Russell, M.A. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Raurell-Vila, H. (Endocrine Regulatory Genomics Laboratory. Germans Trias i Pujol University Hospital and Research Institute) ; Castela, A. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Juan-Mateu, J. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Webb-Robertson, B.J.M. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Krogvold, L. (Division of Pediatric and Adolescent Medicine. Faculty of Medicine. Oslo University Hospital) ; Dahl-Jorgensen, K. (Division of Pediatric and Adolescent Medicine. Faculty of Medicine. Oslo University Hospital) ; Marselli, L. (Department of Clinical and Experimental Medicine. Islet Cell Laboratory. University of Pisa) ; Marchetti, P. (Department of Clinical and Experimental Medicine. Islet Cell Laboratory. University of Pisa) ; Richardson, S.J. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Morgan, N.G. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Metz, T.O. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Pasquali, Lorenzo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Eizirik, D.L. (Indiana Biosciences Research Institute) ; Universitat Autònoma de Barcelona
Interferon-α (IFNα), a type I interferon, is expressed in the islets of type 1 diabetic individuals, and its expression and signaling are regulated by T1D genetic risk variants and viral infections associated with T1D. [...]
2020 - 10.1038/s41467-020-16327-0
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 2584  
9.
21 p, 678.9 KB Porcine Digestible Peptides (PDP) in Weanling Diets Regulates the Expression of Genes Involved in Gut Barrier Function, Immune Response and Nutrient Transport in Nursery Pigs / González-Solé, Francesc (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Criado Mesas, Lourdes (Centre de Recerca en Agrigenòmica) ; Villodre, Carmen (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Coloma Garcia, Wellington Napoleon (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Farré, Mercè (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Borda, Elisabet (Bioiberica S.A.U. Departament de Ciència Animal i dels Aliments) ; Pérez-Cano, Francisco J (Universitat de Barcelona. Departament de Bioquímica i Fisiologia) ; Folch Albareda, Josep Maria (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Solà Oriol, David (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Pérez Hernández, José Francisco (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Criado Mesas, Lourdes (Universitat Autònoma de Barcelona. Centre de Recerca en Genòmica Agrícola)
This study was conducted to investigate the effects of dietary supplementation of porcine digestible peptides (PDP), spray-dried plasma (SDP), or a combination of both, on growth performance and the expression of genes related to intestinal function of weaned pigs. [...]
2020 - 10.3390/ani10122368
Animals, Vol. 10 Núm. 12 (2020) , p. 2368  
10.
16 p, 2.3 MB Electroless Palladium-Coated Polymer Scaffolds for Electrical Stimulation of Osteoblast-Like Saos-2 Cells / Careta, Oriol (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Salicio-Paz, Asier (Basque Research and Technology Alliance (BRTA). CIDETEC) ; Pellicer Vilà, Eva M. (Eva Maria) (Universitat Autònoma de Barcelona. Departament de Física) ; Ibáñez, Elena (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia.) ; Fornell Beringues, Jordina (Universitat Autònoma de Barcelona. Departament de Física) ; García-Lecina, Eva (IK4-CIDETEC. Unidad de Superfícies Metálicas) ; Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física) ; Nogués, C (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Three-dimensional porous scaffolds offer some advantages over conventional treatments for bone tissue engineering. Amongst all non-bioresorbable scaffolds, biocompatible metallic scaffolds are preferred over ceramic and polymeric scaffolds, as they can be used as electrodes with different electric field intensities (or voltages) for electric stimulation (ES). [...]
2021 - 10.3390/ijms22020528
International journal of molecular sciences, Vol. 22, Num. 2 (January 2021) , art. 528  

Articles : 76 registres trobats   1 - 10següentfinal  anar al registre:
Llibres i col·leccions 1 registres trobats  
1.
65 p, 1.6 MB Status and Prospects of systems biology in grapevine research / Matus, José Tomás (Universitat de València. Institut de Biologia Integrativa de Sistemes) ; Ruggieri, Valentino (Centre de Recerca en Agrigenòmica) ; Romero, Francisco José (Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial) ; Moretto, Marco (Fondazione Edmund Mach. Centro Ricerca e Innovazione) ; Wong, Darren C. J. (Australian National University. Research School of Biology)
The cultivated grapevine, Vitis vinifera L. , has gathered a vast amount of omics data throughout the last two decades, driving the imperative use of computational resources for its analysis and integration. [...]
[s. l.] : Springer, 2019 (Compendium of Plant Genomes) - 10.1007/978-3-030-18601-2_8
The Grape Genome, 2019, p. 137-166  

Documents de recerca 5 registres trobats  
1.
1 p, 796.0 KB Quorum sensing : a tool for autoinducible heterologous protein expression / Requena Fernández, Arnau ; Gibert, Isidre, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Projecte de recerca per a l'obtenció d'una soca d'Escherichia coli que utilitzi la comunicació intercel·lular quorum sensing com a inductor per a l'expressió heteròloga de proteïnes. D'aquesta manera és possible activar l'expressió proteica a altes densitats cel·lulars en bioreactors sense la necessitat d'afegir inductors externs com ara IPTG.
Proyecto de investigación para la obtención de una cepa de Escherichia coli que utilice la comunicación intercelular quorum sensing como inductor para la expresión heteróloga de proteínas. De esta forma es posible activar la expresión proteica a altas densidades celulares en bioreactores sin la necesidad de añadir inductores externos como IPTG.
A research proposal has been designed in order to obtain an Escherichia coli strain that uses quorum sensing cell to cell communication as an inductor to promote heterologous protein expression. In this way, it is possible to have protein production activated at high cell densities in bioreactors without the need of externally added inducers like IPTG.

2019-05-25
Grau en Biotecnologia [815]  
2.
1 p, 597.6 KB Fighting against the genetic quorum sensing of Legionella pneumophila / Igual López, Marina Ascensión ; Gibert, Isidre, dir., (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Genètica [833]  
3.
1 p, 642.4 KB Post-translational modifications of histones linked with gliomas : H3K27me3 (¿Methylated or demethylated?, that is the question) / Fábregas Ordóñez, Cristina ; Roque Córdova, Alicia, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Biotecnologia [815]  
4.
1 p, 1.3 MB An approach to the effects of cocaine and alcohol in astrocytes / Rierola Carrera, M. ; Masgrau Juanola, Roser, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
5.
267 p, 5.2 MB Molecular analysis of the mechanisms involved in THBS4 differential geneexpression in the human brain / Rubio Acero, Raquel ; Cáceres Aguilar, Mario, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Durante las últimas décadas ha crecido el interés en cuestiones como qué nos hace humanos o cómo difiere a nivel molecular el cerebro humano del de nuestros parientes más cercanos. Se han podido identificar cientos de genes con diferencias de expresión entre el ser humano y otros primates no humanos. [...]
The last decades have seen a growing interest in what makes us humans and how the human brain differs from that of our closest relatives at the molecular level. Hundreds of genes with expression differences between human and non-human primates have been identified. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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