Results overview: Found 3 records in 0.02 seconds.
Articles, 2 records found
Research literature, 1 records found
Articles 2 records found  
1.
17 p, 936.9 KB Hypoxia : the cornerstone of glioblastoma / Domènech Viñolas, Marta (Institut Català d'Oncologia) ; Hernández, Ainhoa (Institut Català d'Oncologia) ; Plaja, Andrea (Institut Català d'Oncologia) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Balañá, Carmen (Institut Català d'Oncologia)
Glioblastoma is the most aggressive form of brain tumor in adults and is characterized by the presence of hypervascularization and necrosis, both caused by a hypoxic microenvironment. In this review, we highlight that hypoxia-induced factor 1 (HIF-1), the main factor activated by hypoxia, is an important driver of tumor progression in GB patients. [...]
2021 - 10.3390/ijms222212608
International journal of molecular sciences, Vol. 22 Núm. 22 (november 2021) , p. 12608  
2.
9 p, 1.0 MB HIF pathway and c-Myc as biomarkers for response to sunitinib in metastatic clear-cell renal cell carcinoma / Maroto Rey, José Pablo (Institut d'Investigació Biomèdica Sant Pau) ; Esteban, Emilio (Department of Oncology, Nuevo HUCA, Oviedo) ; Parra, E. Fernández (Department of Oncology, H. U. Nuestra Señora de Valme, Sevilla) ; Mendez-Vidal, M. J. (Department of Oncology, H. U. Reina Sofía, Córdoba) ; Domènech, Montserrat (Fundació Althaia) ; Pérez-Valderrama, Begoña (Department of Oncology, H. U. Virgen del Rocio, Sevilla) ; Calderero, V (Department of Oncology, H. Fundación Miguel Servet, Zaragoza) ; Pérez-Gracia, J. L. (Department of Oncology, Clinica Universitaria de Pamplona, Pamplona) ; Grande, Enrique (Hospital Universitario Ramón y Cajal (Madrid)) ; Algaba, Ferran (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Clear-cell renal cell carcinoma (ccRCC) is a heterogeneous disease with a different clinical behavior and response to targeted therapies. Differences in hypoxia-inducible factor (HIF) expression have been used to classify von Hippel-Lindau gene (VHL)-deficient ccRCC tumors. [...]
2017 - 10.2147/OTT.S137677
OncoTargets and therapy, Vol. 10 (september 2017) , p. 4635-4643  

Research literature 1 records found  
1.
1 p, 540.3 KB Hypoxia-inducible factors : from health to cancer / Pérez Roca, Joan ; Fábregas Batlle, Pere Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  

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