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9 p, 3.7 MB |
The Genome-wide Methylation Profile of CD4+ T Cells From Individuals With Human Immunodeficiency Virus (HIV) Identifies Distinct Patterns Associated With Disease Progression
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Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Lopez, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gómez Moruno, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Passaes, Caroline (Institut Pasteur) ;
Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Saez-Cirion, Asier (Institut Pasteur) ;
Clotet, Bonaventura (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
BACKGROUND: Human genetic variation-mostly in the human leukocyte antigen (HLA) and C-C chemokine receptor type 5 (CCR5) regions-explains 25% of the variability in progression of human immunodeficiency virus (HIV) infection. [...]
2021 -  10.1093/cid/ciaa1047
Clinical Infectious Diseases, Vol. 72 Núm. 9 (april 2021) , p. e256-e264
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7 p, 229.3 KB |
Incidence of Recurrent High-Grade Anal Dysplasia in HIV-1-Infected Men and Women Following Infrared Coagulation Ablation : A Retrospective Cohort Study
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Corral, Javier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Parés, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Garcia Cuyàs, Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revollo, Boris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Chamorro, Ana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lecumberri, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tarrats, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castella, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Piñol, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Videla, Sebastià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sirera, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
This single-center, retrospective cohort study sought to estimate the cumulative incidence in HIV-1-infected patients of biopsy-proven high-grade anal intraepithelial neoplasia (HGAIN) recurrence after infrared coagulation (IRC) treatment. [...]
2021 - 10.3390/pathogens10020208
Pathogens, Vol. 10 (february 2021)
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3.
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17 p, 6.0 MB |
Evolution of the gut microbiome following acute HIV-1 infection
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Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pastor, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Guillén Montalbán, Yolanda (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Langhorst, Jost (University of Duisburg-Essen. Chair for Integrative Medicine and translationale Gastroenterology, Klinikum Bamberg) ;
Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rodríguez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Calle, Maria Luz (Universitat de Vic - Universitat Central de Catalunya) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
In rhesus macaques, simian immunodeficiency virus infection is followed by expansion of enteric viruses but has a limited impact on the gut bacteriome. To understand the longitudinal effects of HIV-1 infection on the human gut microbiota, we prospectively followed 49 Mozambican subjects diagnosed with recent HIV-1 infection (RHI) and 54 HIV-1-negative controls for 9-18 months and compared them with 98 chronically HIV-1-infected subjects treated with antiretrovirals (n = 27) or not (n = 71). [...]
2019 - 10.1186/s40168-019-0687-5
Microbiome, Vol. 7 (may 2019)
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4 p, 481.9 KB |
Ambrisentan use in a HIV-1 infected patient with end-stage renal disease and pulmonary hypertension : minimal removal by hemodialysis - a case report
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Santos, José Ramón (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Merino Ribas, Ana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Haefeli, Walter E. (Heidelberg University Hospital (Alemanya)) ;
Miranda, Cristina (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ;
Prats, Marisol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bancu, Ioana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bailón, Lucía (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ;
Moltó, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Ambrisentan is a selective endothelin receptor antagonist used for the treatment of pulmonary arterial hypertension (PAH). Little is known about ambrisentan removal by hemodialysis in patients with end-stage renal disease (ESRD). [...]
2020 - 10.1186/s12882-019-1659-5
BMC Nephrology, Vol. 21 (january 2020)
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14 p, 278.2 KB |
Multidisciplinary, evidence-based consensus guidelines for human papillomavirus (HPV) vaccination in highrisk populations, Spain, 2016
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Martínez-Gómez, Xavier (Hospital Universitari Vall d'Hebron) ;
Curran, Adrian (Hospital Universitari Vall d'Hebron) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Alemany, L. (Institut Català d'Oncologia) ;
Rodrigo-Pendás, J.Á. (Hospital Universitari Vall d'Hebron) ;
Borruel, Natalia (Hospital Universitari Vall d'Hebron) ;
Castellsagué, X. (Institut Català d'Oncologia) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron) ;
Moraga-Llop, F.A. (Asociación Española de Vacunología) ;
del Pino, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Torné, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Universitat Autònoma de Barcelona
Introduction: Although human papillomavirus (HPV) routine vaccination programmes have been implemented around the world and recommendations have been expanded to include other high-risk individuals, current recommendations often differ between countries in Europe, as well as worldwide. [...]
2019 - 10.2807/1560-7917.ES.2019.24.7.1700857
Eurosurveillance, Vol. 24 Núm. 7 (14 2019) , p. 1700857
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14 p, 3.6 MB |
Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1
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Perez-Zsolt, D. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Cantero, Jon (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Benet, S. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Pino, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Serra-Peinado, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández Gallego, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castellví, J. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Tapia, G. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Arnau-Saz, V. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garrido, J. (Hospital Municipal de Badalona) ;
Tarrats, A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Buzón, M.J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez-Picado, J. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Izquierdo-Useros, N. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Genescà Ferrer, Meritxell. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Antigen presenting cells from the cervical mucosa are thought to amplify incoming HIV-1 and spread infection systemically without being productively infected. Yet, the molecular mechanism at the cervical mucosa underlying this viral transmission pathway remains unknown. [...]
2019 - 10.3389/fimmu.2019.00825
Frontiers in immunology, Vol. 10 (april 2019) , p. 825
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7 p, 628.1 KB |
Clinical and Emotional Factors Related to Erectile Dysfunction in HIV-Infected Men
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Fumaz, Carmina R. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ayestaran, Aintzane (Universitat Politècnica de Catalunya) ;
Perez-Alvarez, Nuria (Universitat Politècnica de Catalunya) ;
Muñoz-Moreno, Jose A. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ferrer, Maria Jose (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Negredo Puigmal, Eugènia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
The prevalence and associated factors of erectile dysfunction (ED) in Human Immunodeficiency Virus (HIV)-infected men remain controversial. The authors evaluated ED, clinical, and emotional variables in a group of 501 HIV-infected men in a cross-sectional 4-month observational study. [...]
2016 - 10.1177/1557988316669041
American Journal of Men's Health, Vol. 11 (september 2016) , p. 647-653
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10 p, 2.9 MB |
Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions
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Arimany-Nardi, Cristina (Instituto de Salud Carlos III) ;
Minuesa, Gerard (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Keller, Thorsten (Department of Pharmacology, School of Medicine, University of Würzburg) ;
Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Koepsell, Hermann (Department of Molecular Plant Physiology and Biophysics, Julius-von-Sachs-Institute, University of Würzburg) ;
Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pastor-Anglada, Marçal (Institut de Recerca Sant Joan de Déu) ;
Universitat Autònoma de Barcelona
Lamivudine (3TC), a drug used in the treatment of HIV infection, needs to cross the plasma membrane to exert its therapeutic action. Human Organic cation transporter 1 (hOCT1), encoded by the SLC22A1 gene, is the transporter responsible for its uptake into target cells. [...]
2016 - 10.3389/fphar.2016.00175
Frontiers in Pharmacology, Vol. 7 (june 2016)
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