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10 p, 3.2 MB |
Association of chronic heart failure with mortality in old intensive care patients suffering from Covid-19
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Bruno, Raphael Romano (Heinrich Heine University Düsseldorf) ;
Wernly, Bernhard (Paracelsus Medical University Salzburg) ;
Wolff, Georg (Heinrich Heine University Düsseldorf) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bollen Pinto, Bernardo (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Kindgen-Milles, Detlef (Heinrich Heine University Düsseldorf) ;
Baldia, Philipp Heinrich (Heinrich Heine University Düsseldorf) ;
Kelm, Malte (Medical Faculty of the Heinrich-Heine University) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sviri, Sigal (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Topeli, Arzu (Hacettepe University Faculty of Medicine) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Kondili, Eumorfia (University Hospital of Heraklion) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Nova Medical School) ;
Leaver, Susannah (St George's University Hospitals NHS Foundation Trust) ;
Boumendil, Ariane (Hôpital Saint-Antoine) ;
De Lange, Dylan W. (Utrecht University) ;
Guidet, Bertrand (Hôpital Saint-Antoine) ;
Flaatten, Hans (Haukeland University Hospital (Bergen, Noruega)) ;
Jung, Christian (Heinrich Heine University Düsseldorf) ;
Universitat Autònoma de Barcelona
Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID-19. [...]
2022 -  10.1002/ehf2.13854
ESC Heart Failure, Vol. 9 (march 2022) , p. 1756-1765
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5 p, 261.3 KB |
Cardiac transplantation in adult patients with congenital heart disease Trasplante cardiaco en pacientes adultos con cardiopatía congénita
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Tauron, Manel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Mirabet Pérez, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz-Guijosa, Christian (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Roselló-Díez, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Montiel Dacosta, Josep Anton (Institut d'Investigació Biomèdica Sant Pau) ;
Ginel, Antonino Jose (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Casellas, Sandra (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Subirana, Maria Teresa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Roig, Eulalia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Padró, Josep Maria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Adult patients with congenital heart disease represent a small proportion of the heart transplant patient population. This group of patients has been traditionally associated with higher early mortality. [...]
2017 - 10.1016/j.circv.2017.02.006
Cirugia Cardiovascular, Vol. 24 Núm. 6 (noviembre 2017) , p. 340-344
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3.
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18 p, 7.0 MB |
Profibrotic, electrical, and calcium-handling remodeling of the atria in heart failure patients with and without atrial fibrillation
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Molina, Cristina E. (University Medical Center Hamburg-Eppendorf) ;
Abu-Taha, Issam H. ;
Wang, Qiongling (Baylor College of Medicine) ;
Roselló-Díez, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Kamler, Marcus (University Hospital Essen (Alemanya)) ;
Nattel, Stanley (McGill University) ;
Ravens, Ursula (Medical Faculty Carl Gustav Carus) ;
Wehrens, Xander H.T. (Baylor College of Medicine) ;
Hove-Madsen, Leif ;
Heijman, Jordi (Maastricht University) ;
Dobrev, Dobromir (University Duisburg-Essen) ;
Universitat Autònoma de Barcelona
Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical, and Cahandling remodeling in the setting of HF, but data in human samples are scarce, particularly regarding Ca2+-handling remodeling. [...]
2018 - 10.3389/fphys.2018.01383
Frontiers in physiology, Vol. 9 Núm. OCT (september 2018) , p. 1383
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4.
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8 p, 316.8 KB |
Solid organ transplantation after hematopoietic stem cell transplantation in childhood : A multicentric retrospective survey
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Faraci, Maura (Istituto G Gaslini) ;
Bertaina, Alice (Stanford University) ;
Dalissier, Arnaud (European Society for Blood and Marrow Transplantation Pediatric Disease Working Party) ;
Ifversen, Marianne (Copenhagen University Hospital) ;
Schulz, Ansgar (University Medical Center) ;
Gennery, Andrew (Great North Children's Hospital) ;
Burkhardt, Birgit (University Hospital of Münster (Alemanya)) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Díaz de Heredia, Cristina (Vall d'Hebron Institut d'Oncologia) ;
Lanino, Edoardo (Istituto G Gaslini) ;
Lankester, Arjan C. (Leiden University Medical Center) ;
Gruhn, Bernd (Jena University Hospital (Alemania)) ;
Matthes-Martin, Susanne Medical University of Vienna ;
Kühl, Joern S. (Universitätsklinikum Leipzig) ;
Varotto, Stefania (University Hospital of Padova (Pàdua, Itàlia)) ;
Paillard, Catherine (Hôpital Hautepierre) ;
Guilmatre, Audrey (Hôpital Armand Trousseau (París, França)) ;
Sastre, Ana (Hospital Universitario La Paz (Madrid)) ;
Abecasis, Manuel (Instute Portugues Oncologia Lisboa) ;
Garwer, Birgit (University Hospital Eppendorf) ;
Sedlacek, Petr (University Hospital Motol) ;
Boelens, Jaap Jan (Memorial Sloan Kettering Cancer Center) ;
Beohou, Eric (European Society for Blood and Marrow Transplantation Pediatric Disease Working Party) ;
Bader, Peter (University Hospital of Frankfurt (Alemanya)) ;
Universitat Autònoma de Barcelona
We report data obtained from a retrospective multicenter pediatric survey on behalf of the European Society for Blood and Marrow Transplantation (EBMT). Information on solid organ transplantation (SOT) performed in pediatric recipients of either autologous or allogeneic hematopoietic stem cell transplantation (HSCT) between 1984 and 2016 was collected in 20 pediatric EBMT Centers (25. [...]
2019 - 10.1111/ajt.15240
American Journal of Transplantation, Vol. 19 Núm. 6 (june 2019) , p. 1798-1805
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19 p, 1.5 MB |
Short-Term Changes in Left and Right Ventricular Cardiac Magnetic Resonance Feature Tracking Strain Following Ferric Carboxymaltose in Patients With Heart Failure : A Substudy of the Myocardial-IRON Trial
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del Canto, Irene (Universitat Politècnica de València) ;
Santas, Enrique (Hospital Clínico Universitario de Valencia) ;
Cardells, Ingrid (Hospital de Manises (València)) ;
Miñana, Gema (Hospital Clínico Universitario de Valencia) ;
Palau, Patricia (Hospital Clínico Universitario de Valencia) ;
Llàcer, Pau (Hospital de Manises (València)) ;
Fácila, Lorenzo (Hospital General Universitario de Valencia) ;
López-Vilella, Raquel (Hospital Universitari i Politècnic La Fe (València)) ;
Almenar Bonet, Luis (Hospital Universitari i Politècnic La Fe (València)) ;
Bodi, Vicente (Hospital Clínico Universitario de Valencia) ;
López-Lereu, Maria P. (Cardiovascular Imaging Unit Ascires Biomedical Group) ;
Monmeneu, Jose V. (Cardiovascular Imaging Unit Ascires Biomedical Group) ;
Sanchis, Juan (Universitat de Valencia) ;
Moratal, David (Universitat Politècnica de València) ;
Maceira, Alicia M. (Universitat de Valencia) ;
De la Espriella, Rafael (Universitat de Valencia) ;
Chorro, Francisco J. (Universitat de Valencia) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona) ;
Núñez, Julio (Universitat de Valencia)
The mechanisms explaining the clinical benefits of ferric carboximaltose (FCM) in patients with heart failure, reduced or intermediate left ventricular ejection fraction, and iron deficiency remain not fully clarified. [...]
2022 - 10.1161/JAHA.121.022214
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 11 (march 2022)
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10 p, 7.4 MB |
Incidence, Treatment and Clinical Impact of Iron Deficiency in Chronic Heart Failure : A Longitudinal Analysis
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Miñana, Gema (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Lorenzo, Miguel (Hospital Clínic Universitari (València)) ;
Ramirez de Arellano, Antonio (HEOR, Viforpharma Group, Zurich, Switzerland) ;
Wächter, Sandra (Medical Department, Viforpharma Group, Zurich, Switzerland) ;
De la Espriella, Rafael (CIBER Cardiovascular, Madrid) ;
Sastre, Clara (Hospital Clínic Universitari (València)) ;
Mollar, Anna (Hospital Clínic Universitari (València)) ;
Núñez, Eduardo (Hospital Clínic Universitari (València)) ;
Bodi, Vicente (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Sanchis, Juan (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Núñez, Julio (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
In patients with heart failure (HF), iron deficiency (ID) is a well-recognized therapeutic target; information about its incidence, patterns of iron repletion, and clinical impact is scarce. This single-centre longitudinal cohort study assessed the rates of ID testing and diagnosis in patients with stable HF, patterns of treatment with intravenous iron, and clinical impact of intravenous iron on HF rehospitalization risk. [...]
2022 - 10.3390/jcm11092559
Journal of clinical medicine, Vol. 11 (may 2022)
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23 p, 1.2 MB |
Circulating heart failure biomarkers beyond natriuretic peptides : review from the Biomarker Study Group of the Heart Failure Association (), European Society of Cardiology ()
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Meijers, Wouter C. (University Medical Center Groningen, The Netherlands) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mebazaa, Alexandre (Université de Paris) ;
Bauersachs, Johann (Hannover Medical School, Germany) ;
Cleland, John G.F. (University of Glasgow) ;
Coats, Andrew J. S. (University of Warwick, Coventry, UK) ;
Januzzi, James L. (Massachusetts General Hospital, Boston, USA) ;
Maisel, Alan S. (University of California, USA) ;
McDonald, Kenneth (St Vincent's University Hospital, Dublin, Ireland) ;
Mueller, Thomas (Hospital of Bolzano, Italy) ;
Richards, A. Mark (National University of Singapore) ;
Seferovic, Petar (Belgrade University, Serbia) ;
Mueller, Christian (University of Basel, Switzerland) ;
de Boer, Rudolf A. (University Medical Center Groningen, The Netherlands) ;
Universitat Autònoma de Barcelona
New biomarkers are being evaluated for their ability to advance the management of patients with heart failure. Despite a large pool of interesting candidate biomarkers, besides natriuretic peptides virtually none have succeeded in being applied into the clinical setting. [...]
2021 - 10.1002/ejhf.2346
European Journal of Heart Failure, Vol. 23 (october 2021) , p. 1610-1632
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12 p, 1.2 MB |
Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes : A Systematic Review and Meta-Analysis
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Xie, Suyi (The Chinese University of Hong Kong) ;
Li, Qi (The Chinese University of Hong Kong) ;
Luk, Andrea O. Y. (The Chinese University of Hong Kong) ;
Lan, Hui-Yao (The Chinese University of Hong Kong) ;
Chan, Paul K. S. (The Chinese University of Hong Kong) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Chan, Francis K. L. (The Chinese University of Hong Kong) ;
Fung, Erik (The Chinese University of Hong Kong) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Background: Growth differentiation factor 15 (GDF-15) is a homeostatic cytokine that regulates neural and cardio-metabolic functions, and its release is increased in response to stress, injury, and inflammation. [...]
2022 - 10.3390/biom12070934
Biomolecules, Vol. 12, Num. 7 (july 2022)
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5 p, 420.5 KB |
Evolocumab has no effects on heart failure with reduced ejection fraction injury biomarkers : The EVO-HF trial
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Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Revuelta-López, Elena (Institut Germans Trias i Pujol) ;
Llibre, Cinta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gastelurrutia, Paloma (Institut Germans Trias i Pujol) ;
Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santiago Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rangel-Sousa, Diego (Hospital Universitario Virgen del Rocío (Andalusia)) ;
Fernández-Cisnal, Agustín (Fundación Investigación Clínico de Valencia-Instituto de Investigación Sanitaria) ;
Miñana, Gema (Universitat de València. Departament de Medicina) ;
Mollar, Anna (Fundación Investigación Clínico de Valencia-Instituto de Investigación Sanitaria) ;
Núñez, Julio (Universitat de València. Departament de Medicina)
Aim: Patients with heart failure with reduced ejection fraction (HFrEF) have not been shown to benefit from statins. We hypothesized that, by limiting disease progression in stable HFrEF of ischaemic etiology, the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab could reduce circulating troponin levels, a surrogate biomarker of myocyte injury and atherosclerosis progression. [...]
2023 - 10.1002/ejhf.2932
European Journal of Heart Failure, Vol. 25 Núm. 8 (august 2023) , p. 1439-1443
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