Resultados globales: 3 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros
Documentos de investigación, Encontrados 1 registros
Artículos Encontrados 2 registros  
1.
15 p, 2.4 MB Effect of BDNF Val66Met on hippocampal subfields volumes and compensatory interaction with APOE-ε4 in middle-age cognitively unimpaired individuals from the ALFA study / Vilor-Tejedor, N. (Universitat Pompeu Fabra) ; Operto, Gregory (Institut Hospital del Mar d'Investigacions Mèdiques) ; Evans, T.E. (Erasmus MC University Medical Center Rotterdam. Department of Clinical Genetics) ; Falcon, Carles (Institut Hospital del Mar d'Investigacions Mèdiques) ; Crous-Bou, M. (Cancer Epidemiology Research Program. Catalan Institute of Oncology (ICO). Hospitalet de Llobregat) ; Minguillón, Carolina Institut Hospital del Mar d'Investigacions Mèdiques ; Cacciaglia, Raffaele Institut Hospital del Mar d'Investigacions Mèdiques ; Milà-Alomà, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Grau-Rivera, Oriol (Institut Hospital del Mar d'Investigacions Mèdiques) ; Suárez-Calvet, Marc (Institut Hospital del Mar d'Investigacions Mèdiques) ; Garrido-Martín, D. (Centre for Genomic Regulation (CRG). The Barcelona Institute for Science and Technology) ; Morán, S. (Cancer Epigenetics and Biology Program (PEBC). Bellvitge Biomedical Biomedical Research Institute (IDIBELL)) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Adams, H.H. (Erasmus MC University Medical Center Rotterdam. Department of Radiology) ; Molinuevo, José Luís (Institut Hospital del Mar d'Investigacions Mèdiques) ; Guigó, R. (Universitat Pompeu Fabra (UPF)) ; Gispert, Juan Domingo (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Background: Current evidence supports the involvement of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism, and the ε4 allele of APOE gene in hippocampal-dependent functions. Previous studies on the association of Val66Met with whole hippocampal volume included patients of a variety of disorders. [...]
2020 - 10.1007/s00429-020-02125-3
Brain Structure and Function, Vol. 225 Núm. 8 (january 2020) , p. 2331-2345  
2.
10 p, 762.5 KB The Influence of DAT1, COMT, and BDNF Genetic Polymorphisms on Total and Subregional Hippocampal Volumes in Early Onset Heavy Cannabis Users / Batalla, Albert (Radboud University) ; Lorenzetti, Valentina (Monash University) ; Chye, Yann (Monash University) ; Yücel, Murat (Monash University) ; Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Bhattacharyya, Sagnik (Institute of Psychiatry) ; Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques (Barcelona, Catalunya)) ; Crippa, José A.S. (Instituto Nacional de Ciência e Tecnologia Translacional em Medicina Translational Medicine (INCT-TM)) ; Martín-Santos, Rocío (Institut Hospital del Mar d'Investigacions Mèdiques (Barcelona, Catalunya))
Introduction: Hippocampal neuroanatomy is affected by genetic variations in dopaminergic candidate genes and environmental insults, such as early onset of chronic cannabis exposure. Here, we examine how hippocampal total and subregional volumes are affected by cannabis use and functional polymorphisms of dopamine-relevant genes, including the catechol-O-methyltransferase (COMT), dopamine transporter (DAT1), and the brain-derived neurotrophic factor (BDNF) genes. [...]
2018 - 10.1089/can.2017.0021
Cannabis and Cannabinoid Research, Vol. 3 (february 2018) , p. 1-10  

Documentos de investigación Encontrados 1 registros  
1.
111 p, 1.8 MB Role of the transcriptional coactivator Crtc1 on hippocampal-dependent associative memory Papel del coactivadortranscripcional Crtc1 en la memoria asociativa dependiente de hipocampo / Chen, Meng ; Saura Antolín, Carlos A., (Carlos Alberto), dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
La enfermedad de Alzheimer (EA) es un trastorno neurodegenerativo y la principal causa de demencia en la vejez. El deterioro cognitivo en la EA se correlaciona con la disfunción sináptica y la pérdida de neuronas. [...]
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder and the main cause of dementia in the elderly. Cognitive decline in AD correlates with synaptic dysfunction and neuron loss. Besides the classical episodic memory impairment symptoms, dementia patients develop deficits in encoding and retrieval of emotional associative memory and fear conditioning. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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