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Articles, 2 records found
Articles 2 records found  
1.
13 p, 4.7 MB Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis / Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rogers, R. B. (Department of Medicine. University of Cambridge. Cambridge Biomedical Campus) ; Roy, A. (Department of Paediatrics. University of Oxford) ; Schneider, P. (Princess Maxima Center for Pediatric Oncology) ; Bardini, Michela (Università degli Studi di Milano-Bicocca) ; Ballerini, Paola (Pediatric Hematology. A. Trousseau Hospital) ; Cazzaniga, Giovanni (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ; Moreno, T. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Revilla, C. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Gut, Marta (Universitat Pompeu Fabra) ; Valsecchi, M. G. (Interfant Trial Data Center. University of Milano-Bicocca) ; Roberts, I. (MRC Molecular Haematology Unit. MRC Weatherall Institute of Molecular Medicine. University of Oxford) ; Pieters, R. (Princess Maxima Center for Pediatric Oncology) ; De Lorenzo, P. (Interfant Trial Data Center. University of Milano-Bicocca) ; Varela, Ignacio (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Stam, R. W. (Princess Maxima Center for Pediatric Oncology) ; Universitat Autònoma de Barcelona
Bcell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1 (MLL-AF4) infant B-cell acute lymphoblastic leukemia remains difficult to model, and the pathogenic contribution in cancer of the reciprocal fusions resulting from derivative translocated-chromosomes remains obscure. [...]
2019 - 10.3324/haematol.2018.206375
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1176-1188  
Detailed record - Creative Commons
2.
19 p, 3.0 MB Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development / Pajoro, Alice (Wageningen University. Laboratory of Molecular Biology) ; Madrigal, Pedro fl. 1586-1594 (Polish Academy of Sciences. Institute of Plant Genetics) ; Muiño, Jose M. (Max-Planck Institute for Molecular Genetics. Department of Computational Molecular Biology) ; Matus, José Tomás (Centre de Recerca en Agrigenòmica) ; Jin, Jian (Centre de Recerca en Agrigenòmica) ; Mecchia, Martin A. (Instituto de Biología Molecular y Celular de Rosario) ; Debernardi, Juan M. (Instituto de Biología Molecular y Celular de Rosario) ; Palatnik, Javier F. (Instituto de Biología Molecular y Celular de Rosario) ; Balazadeh, Salma (University of Potsdam. Institute of Biochemistry and Biology) ; Arif, Muhammad (University of Potsdam. Institute of Biochemistry and Biology) ; Ó'Maoiléidigh, Diarmuid S. (Trinity College Dublin. Smurfit Institute of Genetics) ; Wellmer, Frank (Trinity College Dublin. Smurfit Institute of Genetics) ; Krajewski, Pawel (Polish Academy of Sciences. Institute of Plant Genetics) ; Riechmann, José Luis (Institució Catalana de Recerca i Estudis Avançats) ; Angenent, Gerco C. (Business Unit Bioscience. Plant Research International) ; Kaufmann, Kerstin (University of Potsdam. Institute of Biochemistry and Biology)
Background: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators of developmental switches and organ specification. [...]
2014 - 10.1186/gb-2014-15-3-r41
Genome biology, Vol. 15 (March 2014) , p. R41  
Detailed record - Creative Commons

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