Results overview: Found 5 records in 0.02 seconds.
Articles, 5 records found
Articles 5 records found  
1.
13 p, 3.0 MB Compliance with good manufacturing practice in the assessment of immunomodulation potential of clinical grade multipotent mesenchymal stromal Cells Derived from Wharton's Jelly / Grau-Vorster, Marta (Universitat Autònoma de Barcelona. Vall d'Hebron Research Institute (VHIR)) ; Rodríguez, Luciano (Banc de Sang i Teixits) ; del Mazo-Barbara, Anna (Banc de Sang i Teixits) ; Mirabel, Clémentine (Banc de Sang i Teixits) ; Blanco, Margarita (Banc de Sang i Teixits) ; Codinach i Creus, Margarita (Banc de Sang i Teixits) ; G. Gómez, Susana (Banc de Sang i Teixits) ; Querol, Sergi (Banc de Sang i Teixits) ; García-López, Joan (Banc de Sang i Teixits) ; Vives, Joaquim (Banc de Sang i Teixits)
The selection of assays suitable for testing the potency of clinical grade multipotent mesenchymal stromal cell (MSC)-based products and its interpretation is a challenge for both developers and regulators. [...]
2019 - 10.3390/cells8050484
Cells, Vol. 8 (2019) , p. 1-13  
2.
15 p, 2.2 MB Shape matters : Effects of silver nanospheres and wires on human alveolar epithelial cells / Stoehr, Linda C. (University of Salzburg. Department of Molecular Biology) ; González, Edgar (Institut Català de Nanotecnologia) ; Stampfl, Andreas (Helmholtz Centre Munich) ; Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ; Duschl, Albert (University of Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Oostingh, G.J. (University of Salzburg. Department of Molecular Biology)
Background: In nanotoxicology, the exact role of particle shape, in relation to the composition, on the capacity to induce toxicity is largely unknown. We investigated the toxic and immunotoxic effects of silver wires (length: 1. [...]
2011 - 10.1186/1743-8977-8-36
Particle and fibre toxicology, Vol. 8 (December 2011) , art. 36  
3.
13 p, 6.0 MB Mesenchymal stem cells induce expression of cD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo / Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs,Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti- inflammatory regulation by Ado. [...]
2017 - 10.3389/fimmu.2017.01577
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-13  
4.
13 p, 6.6 MB Inflammatory conditions dictate the effect of Mesenchymal stem or Stromal cells on B cell function. / Luk, Franka (Erasmus University Medical Center, Rotterdam) ; Carreras-Planella, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Korevaar, Sander S. (Erasmus University Medical Center, Rotterdam) ; de Witte, Samantha F. H. (Erasmus University Medical Center, Rotterdam) ; Borràs, Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Betjes, Michiel G. H. (Erasmus University Medical Center, Rotterdam) ; Baan, Carla C. (Erasmus University Medical Center, Rotterdam) ; Hoogduijn, Martin J. (Erasmus University Medical Center, Rotterdam) ; Franquesa, Marcella (Erasmus University Medical Center, Rotterdam)
The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising tool for treatment of immune disease and organ transplantation. The effects of MSC on B cells are characterized by an abrogation of plasmablast formation and induction of regulatory B cells (Bregs). [...]
2017 - 10.3389/fimmu.2017.01042
Frontiers in immunology, Vol. 8 (august 2017) , p. 1-13  
5.
15 p, 2.3 MB Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine / Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Pujal, Josep Maria (Universitat de Girona. Laboratori de processament cel·lular) ; Aran Canals, Gemma (Institut Germans Trias i Pujol) ; Sanjurjo, Lucía (Institut Germans Trias i Pujol) ; Franquesa, Marcel·la (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs, Francesc E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted extracellular vesicles (EVs) are envisaged as a promising natural source of nanoparticles to increase outcomes in organ transplantation and control inflammatory diseases. [...]
2017 - 10.7150/thno.16154
Theranostics, Vol. 7 Núm. 2 (2017) , p. 270-284  

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