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1.
14 p, 1.2 MB Systemic oncological treatments in patients with advanced pancreatic cancer: a scoping review and evidence map / Salazar, Josefina (Institut d'Investigació Biomèdica Sant Pau) ; Bracchiglione, Javier (Institut d'Investigació Biomèdica Sant Pau) ; Acosta-Dighero, Roberto (Universidad de Valparaíso, Chile) ; Meza, Nicolas (Universidad de Valparaíso, Chile) ; Meade, Adriana-G. (Institut d'Investigació Biomèdica Sant Pau) ; María Jesús Quintana (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Requeijo, Carolina (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez-Grijalva, Gerardo (Institut d'Investigació Biomèdica Sant Pau) ; Santero, Marilina (Institut d'Investigació Biomèdica Sant Pau) ; Selva, Anna (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ; Bonfill, Xavier (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Appropriateness of Systemic Oncological Treatments for Advanced Cancer (ASTAC) Research Group
Purpose: To identify, describe, and organise currently available evidence regarding systemic oncological treatments (SOTs) (chemotherapy, targeted/biological therapies, and immunotherapy) compared to best supportive care (BSC) for patients with advanced pancreatic cancer (PC). [...]
2023 - 10.1007/s00520-022-07564-8
Supportive Care in Cancer, Vol. 31 Núm. 2 (January 2023)
3 documents
2.
Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach : Practical recommendations from the spanish oncology genitourinary (sogug) working group / Rubio-briones, J. ; Algaba, Ferran (Institut d'Investigació Biomèdica Sant Pau) ; Gallardo, Eduard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Marcos-rodríguez, J.A. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ; Climent, M.Á. (Medical Oncology Service. Fundación Instituto Valenciano de Oncología) ; Gomez-Caamaño, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Vicente, A.M.G. ; Maroto, Pablo (Institut d'Investigació Biomèdica Sant Pau) ; Antolín, A.R. ; Sanz, J. ; González, M.A.V. ; Del Alba, A.G. ; Moreno, A.J.C. ; González-Haba, E.. ; González-peramato, P. ; Espinós, E.L. ; López-beltran, A. ; Pelechano, P. ; Garrido, M. ; Sarrió, R.G. ; Zapatero, A. ; Arranz, J.Á. ; Universitat Autònoma de Barcelona
On the basis of the discussion of the current state of research on relevant topics of non-muscle-invasive bladder cancer (NMIBC) among a group of experts of the Spanish Oncology Gen-itourinary (SOGUG) Working Group, recommendations were proposed to overcome the challenges posed by the management of NMIBC in clinical practice. [...]
2021 - 10.3390/cancers13194762
Cancers, Vol. 13 Núm. 19 (October 2021) , p. 4762  
3.
Pretreatment tissue TCR repertoire evenness is associated with complete pathologic response in patients with NSCLC receiving neoadjuvant chemoimmunotherapy / Casarrubios, M. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Cruz-Bermúdez, A. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Nadal, E. (Institut Català d'Oncologia. L'Hospitalet de Llobregat) ; Insa, Amelia (Hospital Clínic Universitari (València)) ; del Rosario García Campelo, M. (Complejo Hospitalario Universitario de A Coruña) ; Lázaro, M. (Hospital Universitario de Vigo) ; Dómine Gómez, Manuel (Hospital Universitario Fundación Jiménez Díaz) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez-Abreu, D. (Hospital Insular de Gran Canaria) ; Martínez-Martí, A. (Vall d'Hebron Institut d'Oncologia) ; de Castro-Carpeño, J. (Hospital Universitario La Paz (Madrid)) ; Cobo, M. (Hospital Regional Universitario de Málaga) ; López-Vivanco, G. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ; Del Barco, E. (Hospital Universitario de Salamanca) ; Caro, R.B. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Viñolas, N. (Hospital Clínic i Provincial de Barcelona) ; Aranda, I.B. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ; Viteri, Santiago (Instituto Oncológico Dr. Rosell. Hospital Universitario Quiron Dexeus. Grupo QuironSalud) ; Massuti, B. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Barquín, M. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Laza-Briviesca, R. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Sierra-Rodero, B. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Parra, E.R. (Department of Translational Molecular Pathology. The University of Texas. MD Anderson Cancer Center) ; Sanchez-Espiridion, B. (Department of Translational Molecular Pathology. The University of Texas. MD Anderson Cancer Center) ; Rocha, P. (Department of Translational Molecular Pathology. The University of Texas. MD Anderson Cancer Center) ; Kadara, H. (Department of Translational Molecular Pathology. The University of Texas. MD Anderson Cancer Center) ; Wistuba, I.I. (Department of Translational Molecular Pathology. The University of Texas. MD Anderson Cancer Center) ; Romero, A. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Calvo, V. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda) ; Provencio, M. (Servicio de Oncología Médica. Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA). Hospital Universitario Puerta de Hierro-Majadahonda)
Purpose: Characterization of the T-cell receptor (TCR) repertoire may be a promising source for predictive biomarkers of pathologic response to immunotherapy in locally advanced non-small cell lung cancer (NSCLC). [...]
2021 - 10.1158/1078-0432.CCR-21-1200
Clinical Cancer Research, Vol. 27 Núm. 21 (November 2021) , p. 5878-5890  
4.
15 p, 607.8 KB PD-L1 testing and clinical management of newly diagnosed metastatic non-small cell lung cancer in Spain : MOREL study / Rubio-Viqueira, B. (Department of Medical Oncology. Quirónsalud Madrid Hospital. Pozuelo de Alarcón) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Lázaro, M. (Department of Medical Oncology. Álvaro Cunqueiro University Hospital) ; Estévez, S.V. (Department of Medical Oncology. Lucus Augusti University Hospital) ; Córdoba-Ortega, J.F. (Department of Medical Oncology. Arnau de Vilanova University Hospital) ; Maiques, I.M. (Department of Medical Oncology. Doctor Peset University Hospital) ; González, J.G. (Department of Medical Oncology. University Clinical Hospital of Santiago de Compostela) ; Cordellat, A.B. (Department of Medical Oncology. Hospital General Universitario de Valencia. Ciberonc) ; Valdivia-Bautista, J. (Department of Medical Oncology. Virgen de Las Nieves University Hospital) ; Arenas, C.G. (Department of Medical Oncology. Msd) ; Sánchez Torres, J.M. (Department of Medical Oncology. La Princesa University Hospital)
Aim: To describe the clinical management and PD-L1 testing of patients with newly diagnosed stage IV non-small cell lung cancer (NSCLC) without driver mutations in Spain. Methods: Multicenter, retrospective study. [...]
2021 - 10.2217/lmt-2021-0008
Lung Cancer Management, Vol. 10 Núm. 4 (december 2021) , p. LMT53  
5.
17 p, 1.0 MB Management of localized muscle-invasive bladder cancer from a multidisciplinary perspective : Current position of the Spanish oncology genitourinary (Sogug)working group / Gomez-Caamaño, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Vicente, A.M.G. (Nuclear Medicine Department. University General Hospital) ; Maroto, Pabo (Institut d'Investigació Biomèdica Sant Pau) ; Antolín, A.R. (Hospital Universitario 12 de Octubre (Madrid)) ; Sanz, J. (Clínica Universidad de Navarra) ; González, M.A.V. (Hospital Clínic Universitari (València)) ; Climent, M.Á. (Fundació Institut Valencià d'Oncologia)
This review presents challenges and recommendations on different aspects related to the management of patients with localized muscle-invasive bladder cancer (MIBC), which were discussed by a group of experts of a Spanish Oncology Genitourinary (SOGUG) Working Group within the framework of the Genitourinary Alliance project (12GU). [...]
2021 - 10.3390/curroncol28060428
Current Oncology, Vol. 28 Núm. 6 (december 2021) , p. 5084-5100  
6.
16 p, 758.5 KB Pd-(L)1 inhibitors as monotherapy for the first-line treatment of non-small-cell lung cancer patients with high pd-l1 expression : A network meta-analysis / Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Cobo, M. (Medical Oncology. Hospital Regional Universitario de Málaga) ; Isla, Dolores (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ; Marquez-Medina, D. (Medical Oncology. University Hospital Miguel Servet) ; Rodriguez-Abreu, D. (Medical Oncology. Hospital Universitario Insular de Gran Canaria) ; Casal-Rubio, J. (Medical Oncology Service. Hospital Álvaro Cunqueiro) ; Bueno, T.M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bernabé-Caro, R. (Medical Oncology Department. Hospital Virgen del Rocío) ; Parente, D.P. (Medical Affairs Department. Roche Farma S.A) ; Ruiz-Gracia, P. (Medical Affairs Department. Roche Farma S.A) ; Arroyo, M.M. (Medical Affairs Department. Roche Farma S.A) ; Paz-Ares, L. (Hospital Universitario 12 de Octubre (Madrid))
Programmed cell death-ligand 1 (PD-L1) has emerged as a potential biomarker for selec-tion of patients more likely to respond to immunotherapy and as a prognostic factor in non-small cell lung cancer (NSCLC). [...]
2021 - 10.3390/jcm10071365
Journal of clinical medicine, Vol. 10 Núm. 7 (april 2021) , p. 1365  
7.
16 p, 2.7 MB Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients / Martín-Carrasco, Clara (Universidad Alfonso X el Sabio. Hospital Clínico Veterinario) ; Delgado-Bonet, Pablo (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX)) ; Tomeo-Martín, Beatriz Davinia (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX)) ; Pastor Milán, Josep (Universitat Autònoma de Barcelona. Fundació Hospital Clínic Veterinari) ; de la Riva, Claudia (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX)) ; Palau-Concejo, Paula (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX)) ; del Castillo, Noemí (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX)) ; Garcia-Castro, Javier (Instituto de Salud Carlos III) ; Perisé-Barrios, Ana Judith (Universidad Alfonso X el Sabio. Unidad de Investigación Biomédica (UIB-UAX))
The use of oncolytic virus is an innovative approach that has shown promising results as a treatment in oncology. Epithelial-derived tumors are the most frequent neoplasms in dogs, but gold standard therapies can be highly invasive procedures. [...]
2022 - 10.3390/vetsci9070327
Veterinary Sciences, Vol. 9 (june 2022)  
8.
16 p, 3.3 MB Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis / Bernardo-Faura, Martí (Centre de Recerca en Agrigenòmica) ; Rinas, Melanie (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ; Wirbel, Jakob (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ; Pertsovskaya, Inna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Pliaka, Vicky (School of Mechanical Engineering, National Technical University of Athens) ; Messinis, Dimitris E. (ProtATonce) ; Vila, Gemma (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sakellaropoulos, Theodore (National Technical University of Athens) ; Faigle, Wolfgang (University of Zurich) ; Stridh, Pernilla (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ; Behrens, Janina R. (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ; Olsson, Tomas (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ; Martin, Roland (University of Zurich) ; Paul, Friedemann (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ; Alexopoulos, Leonidas G. (ProtATonce) ; Villoslada, Pablo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Saez-Rodriguez, Julio (Heidelberg University Hospital (Alemanya))
Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may produce severe side effects. [...]
2021 - 10.1186/s13073-021-00925-8
Genome Medicine, Vol. 13 (July 2021) , art. 117  
9.
11 p, 1.1 MB ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy / Bousquet, Jean (MACVIA-France) ; Pfaar, Oliver (Philipps-Universität Marburg. University Hospital Marburg) ; Agache, Ioana (Transylvania University Brasov) ; Bedbrook, Anna (MACVIA-France) ; Akdis, Cezmi A.. (University of Zurich. Swiss Institute of Allergy and Asthma Research (SIAF)) ; Canonica, G. Walter (Humanitas Clinical and Research Center IRCCS) ; Chivato, Tomas (University CEU San Pablo) ; Al-Ahmad, Mona (Al-Rashed Allergy Center) ; Abdul Latiff, Amir Hamzah (Pantai Hospital Kuala Lumpur. Allergy & Immunology Centre) ; Ansotegui, Ignacio J. (Hospital Quironsalud Bizkaia) ; Bachert, Claus (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Baharuddin, Abdullah (Universiti Sains Malaysia. School of Medical Sciences) ; Bergmann, Karl-Christian (Humboldt-Universität zu Berlin) ; Bindslev-Jensen, Carsten (Research Center for Anaphylaxis (ORCA)) ; Bjermer, Leif (University Hospital) ; Bonini, Matteo (Royal Brompton Hospital & Imperial College London. National Heart and Lung Institute) ; Bosnic-Anticevich, Sinthia (Woolcock Emphysema Centre and Sydney Local Health District) ; Bosse, Isabelle (Allergist) ; Brough, Helen A. (King's College Hospital NHS Foundation Trust) ; Brussino, Luisa (University of Torino & Mauriziano Hospital) ; Calderon, Moises A. (Imperial College and National Heart and Lung Institute) ; Caraballo, Luis (Foundation for the Development of Medical and Biological Sciences (Fundemeb)) ; Cardona, Victoria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carreiro-Martins, Pedro (Comprehensive Health Research Center (CHRC). CEDOC. NOVA Medical School) ; Casale, Thomas (University of South Florida) ; Cecchi, Lorenzo (USL Toscana Centro) ; Cepeda Sarabia, Alfonso M. (Asma e Immunologia. SLaai, Sociedad Latinoamericana de Allergia) ; Chkhartishvili, Ekaterine (David Tvildiani Medical University-AIETI Medical School) ; Chu, Derek K. (McMaster University. Departments of Medicine and Health Research Methods) ; Cirule, Ieva (University Children Hospital. Latvain Association of Allergists) ; Cruz, Alvaro A. (Federal University of Bahia and GARD/WHO Planning Group. Fundação ProAR) ; Czarlewski, Wienczyslawa (Medical Consulting Czarlewski) ; Del Giacco, Stefano (University of Cagliari. University Hospital "Duilio Casula") ; Demoly, Pascal (Sorbonne Université. Equipe EPAR - IPLESP) ; Devillier, Philippe (Université Paris Saclay. Pôle des Maladies des Voies Respiratoires, Hôpital Foch) ; Dokic, Dejan (University Clinic of Pulmology and Allergy) ; Durham, Stephen L. (Imperial College London. National Heart and Lung Institute) ; Ebisawa, Motohiro (NHO Sagamihara National Hospital) ; El-Gamal✝, Yehia (Ain Shams University. Children's Hospital) ; Emuzyte, Regina (Vilnius University. Clinic of Children's Diseases) ; Gamkrelidze, Amiran (National Center for Disease Control and Public Health of Georgia) ; Fauquert, Jean Luc (Hopital Estaing. Pole pédiatrique. Unité d'Allergologie de l'Enfant) ; Fiocchi, Alessandro (Bambino Gesù Children's Hospital) ; Fokkens, Wytske J. (EUFOREA) ; Fonseca, Joao A. (CUF Porto. Allergy Unit) ; Fontaine, Jean-François (Allergist) ; Gawlik, Radoslaw (Silesian University of Medicine) ; Gelincik, Asli (Dışkapı Yıldırım Beyazıt Training and Research Hospital) ; Gemicioglu, Bilun (Istanbul University-Cerrahpasa) ; Gereda, Jose E. (Clinica Ricardo Palma) ; Gerth van Wijk, Roy (Erasmus MC) ; Gómez, R. Maximiliano (Instituto Medico Alas) ; Gotua, Maia (Georgian Association of Allergology and Clinical Immunology. Center of Allergy and Immunology) ; Grisle, Ineta (Center of Tuberculosis and Lung Diseases. Latvian Association of Allergists) ; Guzmán, Maria-Antonieta (University of Chile. Clinical Hospital) ; Haahtela, Tari (Helsinki University Hospital (Finlàndia)) ; Halken, Susanne (Odense University Hospital. Hans Christian Andersen Children's Hospital) ; Heffler, Enrico (Humanitas University) ; Hoffmann-Sommergruber, Karin (Medical University of Vienna) ; Hossny, Elham (Ain Shams University. Children's Hospital) ; Hrubiško, Martin (Oncology Institute of St Elisabeth) ; Irani, Carla (Hotel Dieu de France Hospital. St Joseph University) ; Ivancevich, Juan Carlos (Clinica Santa Isabel) ; Ispayeva, Zhanat (Kazakhstan Association of Allergology and Clinical Immunology) ; Julge, Kaja (Tartu University Hospital (Tartu, Estònia)) ; Kaidashev, Igor (Ukrainina Medical Stomatological Academy) ; Kalayci, Omer (Hacettepe University School of Medicine) ; Khaitov, Musa (Laboratory of Molecular Immunology. Federal Medicobiological Agency. Institute of Immunology) ; Klimek, Ludger (Center for Rhinology and Allergology) ; Knol, Edward (University Medical Center Utrecht) ; Kowalski, Marek L. (Medical University of Lodz. Healthy Ageing Research Center) ; Kraxner, Helga (Semmelweis University. Head and Neck Surgery) ; Kull, Inger (Södersjukhuset. Sach's Children and Youth Hospital) ; Kuna, Piotr (Medical University of Lodz. Barlicki University Hospital) ; Kvedariene, Violeta (Vilnius University. Clinic of Chest Diseases and Allergology. Institute of Clinical Medicine) ; Kritikos, Vicky (Royal Prince Alfred Hospital) ; Lauerma, Antti (University of Helsinki and Helsinki University) ; Lau, Susanne (Charité - Universitätsmedizin Berlin) ; Laune, Daniel (KYomed INNOV) ; Levin, Michael (University of Cape Town) ; Larenas-Linnemann, Desiree E. (Médica Sur Clinical Foundation and Hospital) ; Lodrup Carlsen, Karin C. (University of Oslo. Institute of Clinical Medicine) ; Lombardi, Carlo (Fondazione Poliambulanza) ; Lourenço, Olga M. (University of Beira Interior. Health Sciences Research Centre. Faculty of Health Sciences and CICS - UBI) ; Mahboub, Bassam (Rashid Hospital) ; Malling, Hans-Jørgen (University of Copenhagen. Danish Allergy Centre) ; Manning, Patrick (Bon Secours Hospital (Dublin, Irlanda)) ; Marshall, Gailen D. (Laboratory of Behavioral Immunology Research. Division of Clinical Immunology and Allergy) ; Melén, Erik (Södersjukhuset. Sach's Children and Youth Hospital) ; Meltzer, Eli O. (Allergy and Asthma Medical Group and Research Center) ; Miculinic, Neven (Croatian Pulmonary Society) ; Milenkovic, Branislava (Serbian Association for Asthma and COPD) ; Moin, Mostafa (Tehran University of Medical Sciences. Immunology and Asthma and Allergy Research Institute) ; Montefort, Stephen (University of Medicine. Mater Dei Hospital Malta) ; Morais-Almeida, Mario (CUF Descobertas Hospital) ; Mortz, Charlotte G. (Odense University Hospital (Dinamarca)) ; Mösges, Ralph (CRI-Clinical Research International-Ltd) ; Mullol, Joaquim (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Namazova Baranova, Leyla (Russian National Research Medical University. Scientific Centre of Children's Health) ; Neffen, Hugo (Center of Allergy, Immunology and Respiratory Diseases) ; Nekam, Kristof (Hospital of the Hospitaller Brothers in Buda) ; Niedoszytko, Marek (Gdańsk. Medical University of Gdańsk) ; Odemyr, Mikaëla (European Federation of Allergy and Airways Diseases Patients' Associations) ; O'Hehir, Robyn E. (Alfred Health, Melbourne) ; Ollert, Markus (Odense University Hospital. Odense Research Center for Anaphylaxis (ORCA)) ; O'Mahony, Liam (University College Cork. APC Microbiome Ireland) ; Ohta, Ken (Tokyo National Hospital. National Hospital Organization) ; Okamoto, Yoshitaka (Chiba University Hospital) ; Okubo, Kimi (Nippon Medical School) ; Pajno, Giovanni B. (University of Messina. Allergy Unit) ; Palomares, Oscar (Complutense University of Madrid. School of Chemistry) ; Palkonen, Susanna (Charles University. Faculty of Medicine in Hradec Králové) ; Panzner, Petr (Charles University. Faculty of Medicine in Hradec Králové) ; G. Papadopoulos, Nikolaos (University of Manchester. Royal Manchester Children's Hospital. Immunity & Respiratory Medicine) ; Park, Hae-Sim (Ajou University School of Medicine) ; Passalacqua, Giovanni (Ospedale Policlino San Martino -University of Genoa. Allergy and Respiratory Diseases) ; Patella, Vincenzo ("Santa Maria della Speranza" Hospital. Agency of Health ASL Salerno. Division of Allergy and Clinical Immunology) ; Pawankar, Ruby (Nippon Medical School) ; Pham-Thi, Nhân (IRBA (Institut de Recherche bio-Médicale des Armées)) ; Plavec, Davor (University J.J. Strossmayer. Children's Hospital Srebrnjak, Zagreb) ; Popov, Todor A. (University Hospital 'Sv Ivan Rilski') ; Recto, Marysia (UP-PGH. Section of Allergy and Immunology) ; Regateiro, Frederico S. (University of Coimbra. CIBB. ICBR - Coimbra Institute for Clinical and Biomedical Research) ; Riggioni, Carmen (Institut de Recerca Sant Joan de Déu) ; Roberts, Graham (Salford Royal NHS Foundation Trust NHS England North) ; Rodriguez-Gonzales, Monica (Hospital Angeles Pedregal. Pediatric Allergy and Clinical Immunology) ; Rosario, Nelson (Universidade Federal do Paraná) ; Rottem, Menachem (Technion - Israel Institute of Technology. Rappaport Faculty of Medicine) ; Rouadi, Philip W. (Eye and Ear University Hospital) ; Ryan, Dermot (University of Edinburgh. Medical School) ; Samolinski, Boleslaw (Medical University of Warsaw. Allergology and Immunology) ; Sanchez-Borges✝, Mario (Centro Medico-Docente La Trinidad) ; Serpa, Faradiba S. (Santa Casa de Misericórdia of Vitória-Espírito Santo. Asthma Reference Center - Escola Superior de Ciencias) ; Sastre, Joaquin (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Scadding, Glenis K. (University College London. The Royal National ENT Hospital) ; Shamji, Mohamed H. (Imperial College London. Allergy and Clinical Immunology) ; Schmid-Grendelmeier, Peter (University Hospital Zurich (Suïssa)) ; Schünemann, Holger J. (McMaster University. Departments of Medicine and Health Research Methods) ; Sheikh, Aziz (The University of Edinburgh. The Usher Institute of Population Health Sciences and Informatics) ; Scichilone, Nicola (University of Palermo. PROMISE Department) ; Sisul, Juan Carlos (Clinica Sisul, Allergy & Asthma. Sociedad Paraguaya de Alergia Asma e Inmunologıa) ; Sofiev, Mikhail (Finnish Meteorological Institute (FMI)) ; Solé, Dirceu (Federal University of São Paulo. Division of Allergy, Clinical Immunology and Rheumatology) ; Sooronbaev, Talant (Euro-Asian Respiratory Society. Kyrgyzstan National Centre of Cardiology and Internal Medicine) ; Soto-Martinez, Manuel (Universidad de Costa Rica. Hospital Nacional de Niños. Division of Respiratory Medicine) ; Soto-Quiros, Manuel (Hospital Nacional de Niños) ; Sova, Milan (University Hospital Olomouc (Olomouc, República Txeca)) ; Schwarze, Jürgen (The University of Edinburgh. Child Life and Health. Centre for Inflammation Research) ; Skypala, Isabel (Royal Brompton and Harefield NHS Foundation Trust) ; Suppli-Ulrik, Charlotte (University of Copenhagen. Institute of Cinical Medicine) ; Taborda-Barata, Luis (Covilhã. University Hospital Centre) ; Todo-Bom, Ana (University of Coimbra. Faculty of Medicine) ; Torres, Maria J. (Instituto de Investigación Biomédica de Málaga) ; Valentin-Rostan, Marylin (Allergist) ; Tomazic, Peter-Valentin (Medical University of Graz. ENT-University Hospital Graz) ; Valero, Antonio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Toppila-Salmi, Sanna (Helsinki University Hospital (Finlàndia)) ; Tsiligianni, Ioanna (International Primary Care Respiratory Group IPCRG) ; Untersmayr, Eva (Medical University of Vienna. Center of Pathophysiology, Infectiology and Immunology. Institute of Pathophysiology and Allergy Research) ; Urrutia-Pereira, Marilyn (Universidade Federal dos Pampa) ; Valiulis, Arunas (European Academy of Paediatrics (EAP/UEMS-SP)) ; Valovirta, Erkka (Terveystalo Allergy Clinic) ; Vandenplas, Olivier (Université Catholique de Louvain. Centre Hospitalier Universitaire UCL Namur) ; Ventura, Maria Teresa (University of Bari Medical School) ; Vichyanond, Pakit (Mahidol University. Siriraj Hospital. Faculty of Medicine) ; Wagenmann, Martin (Universitätsklinikum Düsseldorf) ; Wallace, Dana (Nova Southeastern University, Fort Lauderdale) ; Walusiak-Skorupa, Jolanta (Nofer Institute of Occupational Medicine) ; Wang, De Yun (National University of Singapore) ; Waserman, Susan (McMaster University (Canadà)) ; Wong, Gary W. K. (Shatin, New Territories. The Chinese University of Hong Kong. Prince of Wales Hospital) ; Yorgancioglu, Arzu (Celal Bayar University) ; Yusuf, Osman M. (The Allergy and Asthma Institute) ; Zernotti, Mario (Universidad Nacional de Villa Maria. Universidad Católica de Córdoba) ; Zhang, Luo (Beijing Institute of Otolaryngology) ; Zidarn, Mihaela (University Clinic of Respiratory and Allergic Diseases (Golnik, Eslovènia)) ; Zuberbier, Torsten (Humboldt-Universität zu Berlin) ; Jutel, Marek (ALL-MED Medical Research Institute) ; Universitat Autònoma de Barcelona
2021 - 10.1002/clt2.12014
Clinical and translational allergy, Vol. 11 (june 2021)  
10.
18 p, 2.6 MB Efficacy of systemic oncological treatments in patients with advanced esophageal or gastric cancers at high risk of dying in the middle and short term : an overview of systematic reviews / Santero, Marilina (Institut d'Investigació Biomèdica Sant Pau) ; Bracchiglione, Javier (Universidad de Valparaíso) ; Acosta-Dighero, Roberto (Universidad San Sebastian) ; Meade, A. G. (Institut d'Investigació Biomèdica Sant Pau) ; Antequera, Alba (Institut d'Investigació Biomèdica Sant Pau) ; Auladell-Rispau, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ; Quintana, M. Jesús (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Requeijo, Carolina (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez-Grijalva, G. (Institut d'Investigació Biomèdica Sant Pau) ; Salas-Gama, Karla (Institut d'Investigació Biomèdica Sant Pau) ; Dorantes-Romandia, R. (Institut d'Investigació Biomèdica Sant Pau) ; Salazar, Josefina (Institut d'Investigació Biomèdica Sant Pau) ; Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ; Urrútia, Gerard (Institut d'Investigació Biomèdica Sant Pau) ; Bonfill, X. (Xavier) (Institut d'Investigació Biomèdica Sant Pau)
Esophageal and gastric cancers are a significant public health problem worldwide, with most patients presenting with advanced-stage disease and, consequently, poor prognosis. Systemic oncological treatments (SOT) have been widely used over more conservative approaches, such as supportive care. [...]
2021 - 10.1186/s12885-021-08330-5
BMC Cancer, Vol. 21 (june 2021)  

Articles : 50 registres trobats   1 - 10següentfinal  anar al registre:
Documents de recerca 18 registres trobats  1 - 10següent  anar al registre:
1.
Natural and Synthetic Hydrogels as Biomimetic Materials for Cancer Immunotherapies / Santos Abreu, Roberto Fabião ; Guasch, Judith, dir. ; Ratera Bastardas, Imma, dir.
La immunoteràpia contra el càncer, la qual es basa en aprofitar el sistema immunitari dels mateixos pacients en comptes de tractar directament el tumor, com ho fan els tractaments convencionals (per exemple, cirurgia, radioteràpia i quimioteràpia), és sens dubte un dels enfocaments terapèutics actualment més prometedors per la lluita contra en càncer. [...]
La inmunoterapia contra el cáncer, se basa en aprovechar el sistema inmunitario de los pacientes en vez de tratar directamente el tumor, como lo hacen los tratamientos convencionales (por ejemplo, cirugía, radioterapia y quimioterapia), es sin duda uno de los enfoques terapéuticos actualmente más prometedores por la lucha contra en cáncer. [...]
Cancer immunotherapy, which is based on harnessing the immune system of patients, instead of directly targeting the tumour as the conventional treatments (e. g. surgery, radiotherapy, and chemotherapy) do, is undoubtedly one of the most promising therapeutic approaches towards the final goal of defeating cancer, as already recognized in 2013 by the journal "Science" as a "Breakthrough of the Year". [...]

2022  
2.
178 p, 1.3 MB Efectes adversos immuno-relacionats i associació amb l'eficàcia de la immunoteràpia en pacients amb càncer de pulmó de cèl·lula no petita / Riudavets Melià, Mariona ; Majem, Margarita, dir. ; Nomdedeu, Josep, dir.
Els inhibidors dels immune-checkpoint han revolucionat l'estratègia terapèutica del càncer de pulmó de cèl·lula no petita (CPCNP). Tot i així poden produir efectes adversos immuno-relacionats o irAEs, que són relativament freqüents i sovint cursen amb símptomes inespecífics, dificultant i endarrerint el seu diagnòstic i fent que avancin a formes més greus, obligant així a la suspensió permanent del tractament. [...]
Los inhibidores de los inmune-checkpoint han revolucionado la estrategia terapéutica del cáncer de pulmón de célula no pequeña (CPCNP). Aún así pueden producir efectos adversos inmuno-relacionados o irAEs, que son frecuentes y a menudo cursan con síntomas inespecíficos, dificultando y retrasando su diagnóstico haciendo que avancen a formas más graves, obligando así a la suspensión permanente del tratamiento. [...]
Immune-checkpoint inhibitors have revolutionized the therapeutic strategy in non-small cell lung cancer (NSCLC). However, given their mechanism of action, they can produce inflammatory-type adverse effects, called immune-related adverse events or irAEs, which are relatively common (60-85%). [...]

2021  
3.
2 p, 1.4 MB CAR-iNKT cells : a new therapeutic approach for multiple myeloma / García Balduz, Jorge ; Universitat Autònoma de Barcelona. Facultat de Biociències
2021
Grau en Bioquímica [814]  
4.
2 p, 580.4 KB Targeting stromal cancer associated fibrobalsts as an adjuvant to immunotherapy for pancreatic cancer / Viñas Casas, Maria ; Universitat Autònoma de Barcelona. Facultat de Biociències
2021
Grau en Bioquímica [814]  
5.
152 p, 7.7 MB 3D Systems for Immune cells culture and their applications in Immunotherapy / Pérez del Río, Eduardo ; Ratera Bastardas, Imma, dir. ; Guasch Camell, Judit, dir. ; Arús i Caraltó, Carles, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Noves fites en el camp de la inmunoteràpia, com el desenvolupament de les cèl·lules T modificades genèticament per teràpia cel·lular adoptiva, estan introduïnt estratègies més eficients per combatre el càncer. [...]
Recientes logros en el campo de la inmunoterapia, como el desarrollo de células T modificadas para su uso como terapia celular adoptivas, están introduciendo estrategias más eficientes para combatir el cáncer. [...]
Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, these T cells are challenging to manufacture, manipulate, and control. [...]

2020  
6.
1 p, 852.4 KB APC Vaccines in iNKT Cell-Mediated Antitumoral Immunotherapy / Garcia-Ortega, Sara ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Ciències Biomèdiques [832]  
7.
1 p, 521.3 KB Invariant Natural Killer T cell-based Immunotherapy against Cancer / Barbao Carrasco, Paula ; Universitat Autònoma de Barcelona. Facultat de Biociències
2018
Grau en Ciències Biomèdiques [832]  
8.
11 p, 1.3 MB Engineered Oncolytic Herpes Simplex Virus as Treatment for Glioblastoma / Rúbies Bedós, Marta ; Universitat Autònoma de Barcelona. Facultat de Biociències
Since they were discovered over a century ago, oncolytic viruses have been expected to produce a cure for cancer. Although results so far have not been promising, the FDA approval of an oncolytic virus (T-VEC) for malignant melanoma in the United States in 2015 has yet opened again the door for this therapy as a potential treatment for cancer. [...]
2018
Grau en Ciències Biomèdiques [832]  
9.
1 p, 1.9 MB Engineered oncolytic viruses as targetd therapy for pancreatic ductal adenocarcinoma / Ramal García, Maria ; Lizcano de Vega, José Miguel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Pancreatic Ductal Adenocarcinoma (PDAC), the most prevalent subtype of pancreatic cancer, is a medical challenge owing to its lethality and the poor effectiveness of current treatments, specially because of the hardly penetrable microenvironment that exerts an immunosuppressive effect. [...]
2019-05-30
Grau en Biotecnologia [815]  
10.
1 p, 2.4 MB CRISPR technology and its application in cancer / Fagoaga Eugui, Maider ; Dunach, Mireia, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
CRISPR is a revolutionary genome-editing technology derived from the adaptive immune system of prokaryotes, which integrate short fragments of foreign nucleic acids in their genome in a specific manner and this serves as a vaccination card or cellular memory of past invaders. [...]
2019-05-31
Grau en Bioquímica [814]  

Documents de recerca : 18 registres trobats   1 - 10següent  anar al registre:
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