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8 p, 894.2 KB |
Fludarabine/Busulfan versus Fludarabine/Melphalan Conditioning in Patients Undergoing Reduced-Intensity Conditioning Hematopoietic Stem Cell Transplantation for Lymphoma
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Kekre, N. (The Ottawa Hospital) ;
Marquez-Malaver, Francisco J. (Instituto de Biomedicina de Sevilla) ;
Cabrero, Monica (Instituto Biosanitario de Salamanca (IBSAL)) ;
Piñana, J. (Hospital Clínic Universitari (València)) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Soiffer, Robert J. (Dana Farber Cancer Institute) ;
Caballero, Dolores (Instituto Biosanitario de Salamanca (IBSAL)) ;
Terol, M.J. (Hospital Clínic Universitari (València)) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Antin, Joseph H. (Harvard Medical School) ;
Lopez-Corral, L. (Instituto Biosanitario de Salamanca (IBSAL)) ;
Solano, Carlos (Hospital Clínic Universitari (València)) ;
Armand, Philippe (Harvard Medical School) ;
Pérez-Simon, Jose A. (Instituto de Biomedicina de Sevilla) ;
Universitat Autònoma de Barcelona
There is at present little data to guide the choice of conditioning for patients with lymphoma undergoing reduced-intensity conditioning (RIC) allogeneic stem cell transplantation (SCT). In this study, we compared the outcomes of patients undergoing RIC SCT who received fludarabine and melphalan (FluMel), the standard RIC regimen used by the Spanish Group of Transplantation, and fludarabine and busulfan (FluBu), the standard RIC regimen used by the Dana-Farber Cancer Institute/Brigham and Women's Hospital. [...]
2016 -  10.1016/j.bbmt.2016.07.006
Biology of blood and marrow transplantation, Vol. 22 Núm. 10 (january 2016) , p. 1808-1815
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12 p, 804.5 KB |
RIC versus MAC UCBT in adults with AML : A report from Eurocord, the ALWP and the CTIWP of the EBMT
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Baron, Frédéric (University of Liege) ;
Ruggeri, Annalisa (Hôpital Saint-Antoine (Paris, França)) ;
Beohou, Eric (Hôpital Saint-Antoine (Paris, França)) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Sanz, Guillermo (Hospital Universitari i Politècnic La Fe (València)) ;
Milpied, Noel (University of Bordeaux) ;
Michallet, Mauricette (Centre Hospitalier de Lyon Sud) ;
Bacigalupo, Andrea (Ospedale San Martino) ;
Blaise, Didier (Aix-Marseille Université) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Socié, Gérard (Hospital Saint-Louis) ;
Cornelissen, Jan J. (Erasmus Medical Center-Daniel den Hoed Cancer Center) ;
Schmid, Christoph (University of Munich) ;
Giebel, Sebastian (Gliwice Branch) ;
Gorin, Norbert-Claude (Hospital Saint Antoine) ;
Esteve, Jordi (Hematology. Hospital Clinic) ;
Ciceri, Fabio (Ospedale San Raffaele) ;
Savani, Bipin N. (Vanderbilt University Medical Center) ;
Mohty, Mohamad (UMRs 938) ;
Gluckman, Eliane (Centre Scientifique de Monaco) ;
Nagler, Arnon (The Chaim Sheba Medical Center) ;
Universitat Autònoma de Barcelona
Nonrelapse mortality (NRM) is the first cause of treatment failure after unrelated cord blood transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade, reduced-intensity conditioning (RIC) regimens have been developed with the aim of reducing NRM and allowing older patients and those with medical comorbidities to benefit from UCBT. [...]
2016 - 10.18632/oncotarget.9599
Oncotarget, Vol. 7 Núm. 28 (2016) , p. 43027-43038
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7 p, 784.4 KB |
Phase II Study of Yttrium-90-Ibritumomab Tiuxetan as Part of Reduced-Intensity Conditioning (with Melphalan, Fludarabine ± Thiotepa) for Allogeneic Transplantation in Relapsed or Refractory Aggressive B Cell Lymphoma : A GELTAMO Trial
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Cabrero, Monica (Hospital Universitario Salamanca i IBSAL (Instituto Biosanitario de Salamanca)) ;
Martín García-Sancho, Alejandro (Hospital Universitario Salamanca i IBSAL (Instituto Biosanitario de Salamanca)) ;
Briones Meijide, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Gayoso, Jorge (Hospital General Universitario Gregorio Marañón) ;
Jarque, Isidro (Hospital Universitari i Politècnic La Fe (València)) ;
López, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Grande García, Carlos (Hospital 12 de Octubre (Madrid)) ;
Heras, Inmaculada (Hospital Morales Messeguer) ;
Arranz, Reyes (Hospital Universitario de la Princesa (Madrid)) ;
Bernal, Teresa (Hospital Universitario Central de Asturias) ;
Perez-Lopez, Estefenia (Hospital Universitario Salamanca i IBSAL (Instituto Biosanitario de Salamanca)) ;
López-Godino, Oriana (Hospital Morales Messeguer) ;
Conde, Eulogio (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Caballero, Dolores (Hospital Universitario Salamanca i IBSAL (Instituto Biosanitario de Salamanca)) ;
Universitat Autònoma de Barcelona
We designed a phase II clinical trial including Y-90 ibritumomab-tiuxetan as part of a reduced-intensity conditioning (RIC) allogeneic stem cell transplantation (AlloSCT) in high-risk non-Hodgkin lymphoma (Clinical Trials Identifier: NCT00644371). [...]
2017 - 10.1016/j.bbmt.2016.10.003
Biology of blood and marrow transplantation, Vol. 23 Núm. 1 (january 2017) , p. 53-59
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9 p, 981.6 KB |
A Time-to-Event Model for Acute Kidney Injury after Reduced-Intensity Conditioning Stem Cell Transplantation Using a Tacrolimus- and Sirolimus-based Graft-versus-Host Disease Prophylaxis
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Piñana, J.L. (Hospital Universitari i Politècnic La Fe de València) ;
Perez-Pitarch, A. (Hospital Clínico Universitario de València) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Hernandez-Boluda, J.C. (Fundación de Investigación INCLIVA) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Fox, Maria Laura (Hospital Universitari Vall d'Hebron) ;
Terol, M.J. (Fundación de Investigación INCLIVA) ;
Queraltó, Josep M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vima, Jaume (Hospital Universitari Vall d'Hebron) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Ferriols-Lisart, R. (Hospital Clínico Universitario de València) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Solano, C. (Universitat de València) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
There is a paucity of data evaluating acute kidney injury (AKI) incidence and its relationship with the tacrolimus-sirolimus (Tac-Sir) concentrations in the setting of reduced-intensity conditioning (RIC) after allogeneic stem cell transplantation (allo-HSCT). [...]
2017 - 10.1016/j.bbmt.2017.03.035
Biology of blood and marrow transplantation, Vol. 23 Núm. 7 (july 2017) , p. 1177-1185
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26 p, 2.5 MB |
What can we know from pituitary-adrenal hormones about the nature and consequences of exposure to emotional stressors?
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Armario Garcia, Antonio (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Daviu, Núria (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Muñoz Abellán, Cristina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Rabasa, Cristina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Fuentes, Silvia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Belda, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Gagliano, Humberto Antonio (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Exposure to stress induces profound physiological and behavioral changes in the organisms and some of these changes may be important regarding stressinduced pathologies and animal models of psychiatric diseases. [...]
2012 - 10.1007/s10571-012-9814-6
Cellular and Molecular Neurobiology, Vol. 32 Núm. 5 (july 2012) , p. 749-758
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8 p, 692.3 KB |
Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma : Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment
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Reinoso-Segura, Marta (Universidad de Sevilla) ;
Caballero Velazquez, Teresa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Herrera, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Patriarca, Francesca (University Hospital and DAME) ;
Fanin, Renato (University Hospital and DAME) ;
Bruno, Benedetto (AOU Città della Salute e della Scienza) ;
Einsele, Hermann (Medizinische Klinik and Poliklinik II University Hospital) ;
Nahi, Hareth (Karolinska University Hospital) ;
Granell, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
López-Corral, Lucía (Centro de Investigación del Cáncer-IBMCC) ;
Reguera, Juan L. (Universidad de Sevilla) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Gahrton, Gösta (European Society for Blood and Marrow Transplantation) ;
Pérez-Simón, José A. (Universidad de Sevilla) ;
Universitat Autònoma de Barcelona
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after allogeneic stem cell transplantation (alloSCT). In contrast, disease relapse remains the most frequent cause of treatment failure and death. [...]
2022 - 10.1016/j.jtct.2022.01.026
Transplantation and Cellular Therapy, Vol. 28 Núm. 5 (may 2022) , p. 258.e1-258.e8
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7 p, 530.8 KB |
Reduced-Intensity versus Myeloablative Conditioning in Cord Blood Transplantation for Acute Myeloid Leukemia (40-60 years) across Highly Mismatched HLA Barriers-On Behalf of Eurocord and the Cellular Therapy & Immunobiology Working Party (CTIWP) of EBMT
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Sheth, Vipul (Fred Hutchison Cancer Research Centre) ;
Volt, Fernanda (Eurocord) ;
Sanz, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Clement, Laurence (Haut-Lévêque) ;
Cornelissen, Jan (Erasmus MC-Daniel den Hoed Cancer Centre) ;
Blaise, Didier (Paoli Calmettes) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Michallet, Mauricette (Centre Leon Berard) ;
Saccardi, Riccardo (Careggi University Hospital (Florència, Itàlia)) ;
Rocha, Vanderson (Eurocord) ;
Gluckman, Eliane (Eurocord) ;
Chabannon, Christian (Institut Paoli-Calmettes) ;
Ruggeri, Annalisa (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Universitat Autònoma de Barcelona
The use of myeloablative conditioning (MAC) in umbilical cord blood transplantation (UCBT) has been associated with high nonrelapse mortality (NRM) in patients aged >40 years, especially those having a high HLA disparity, thus limiting wider applications. [...]
2020 - 10.1016/j.bbmt.2020.07.025
Biology of blood and marrow transplantation, Vol. 26 Núm. 11 (november 2020) , p. 2098-2104
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Effects of livestock grazing on the relationships between soil microbial
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Xu, Hongwei (Sichuan Agricultural University) ;
You, Chengming (Sichuan Agricultural University) ;
Ton, Ba (Sichuan Agricultural University) ;
Xu, Lin (Sichuan Agricultural University) ;
Liu, Yang (Sichuan Agricultural University) ;
Wang, Minggang (Beijing Forestry University) ;
Xu, Zhenfeng (Sichuan Agricultural University) ;
Sardans i Galobart, Jordi (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Livestock grazing of grassland ecosystems may induce shifts in microbe community traits and soil carbon (C) cycling; however, impacts of grassland management (grazing) on soil C- microbe community trait (microbial biomass, diversity, community structure, and enzyme activity) relationships are unclear. [...]
2023 - 10.1016/j.scitotenv.2023.163416
Science of the total environment, Vol. 881 (July 2023) , art. 163416
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10 p, 678.7 KB |
Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke
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Hong, Sungmin (Massachusetts General Hospital) ;
Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ;
Schirmer, Markus D. (University Hospital Bonn) ;
Bonkhoff, Anna K. (Massachusetts General Hospital) ;
Bretzner, Martin (Université du Lille) ;
Rist, Pamela (Brigham and Women's Hospital) ;
Dalca, Adrian V. (Department of Radiology, Massachusetts General Hospital) ;
Regenhardt, Robert W. (Massachusetts General Hospital) ;
Etherton, Mark R. (Massachusetts General Hospital) ;
Donahue, Kathleen L. (Massachusetts General Hospital) ;
Nardin, Marco (Harvard Medical School) ;
Mocking, Steven J. T. (Massachusetts General Hospital) ;
McIntosh, Elissa C. (Massachusetts General Hospital) ;
Attia, John (University of Newcastle) ;
Benavente, Oscar R. (University of British Columbia) ;
Cole, John W. (University of Maryland. School of Medicine) ;
Donatti, Amanda (University of Campinas) ;
Griessenauer, Christoph J. (Research Institute of Neurointervention, Paracelsus Medical University) ;
Heitsch, Laura (Washington University School of Medicine) ;
Holmegaard, Lukas (University of Gothenburg) ;
Jood, Katarina (University of Gothenburg) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kittner, Steven J. (University of Maryland School of Medicine) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R. (John Hunter Hospital) ;
McDonough, Caitrin W. (University of Florida) ;
Meschia, James F. (Mayo Clinic (Estats Units d'Amèrica)) ;
Phuah, Chia-Ling (Department of Neurology, Washington University School of Medicine & Barnes-Jewish Hospital) ;
Rolfs, Arndt (Centogene AG (Alemanya)) ;
Ropele, Stefan (Department of Neurology, Medical University Graz) ;
Rosand, Jonathan (Massachusetts General Hospital) ;
Rundek, Tatjana (Department of Neurology, University of Miami) ;
Sacco, Ralph L. (Department of Neurology , University of Miami) ;
Schmidt, Reinhold (Department of Neurology, Medical University Graz) ;
Enzinger, Christian (Department of Neurology, Medical University Graz) ;
Sharma, Pankaj (St. Peter's and Ashford Hospitals) ;
Slowik, Agnieszka (Jagiellonian University Medical College) ;
Sousa, Alessandro (University of Campinas) ;
Stanne, Tara M. (University of Gothenburg) ;
Strbian, Daniel (University of Helsinki) ;
Tatlisumak, Turgut (Sahlgrenska University Hospital) ;
Thijs, Vincent (Austin Health (Austràlia)) ;
Vagal, Achala (University of Cincinnati College of Medicine) ;
Wasselius, Johan (Skåne University Hospital (Suècia)) ;
Woo, Daniel (University of Cincinnati College of Medicine) ;
Zand, Ramin (Geisinger (Estats Units d'Amèrica)) ;
McArdle, Patrick F. (University of Maryland School of Medicine) ;
Worrall, Bradford B. (University of Virginia) ;
Wu, Ona (Massachusetts General Hospital) ;
Jern, Christina (Department of University of Gothenburg) ;
Lindgren, Arne G. (Lund University. Department of Clinical Sciences) ;
Maguire, Jane (University of Technology Sydney) ;
Tomppo, Liisa (University of Helsinki) ;
Golland, Polina (Massachusetts Institute of Technology) ;
Rost, Natalia S. (Massachusetts General Hospital) ;
Universitat Autònoma de Barcelona
Objective: To personalize the prognostication of post-stroke outcome using MRI-detected cerebrovascular pathology, we sought to investigate the association between the excessive white matter hyperintensity (WMH) burden unaccounted for by the traditional stroke risk profile of individual patients and their long-term functional outcomes after a stroke. [...]
2021 - 10.3389/fneur.2021.700616
Frontiers in neurology, Vol. 12 (september 2021)
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