Home > Search Results: Interleukin-17
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Articles, 2 records found
Articles 2 records found  
1.
14 p, 632.2 KB Efficacy and Safety of Netakimab, A Novel Anti-IL-17 Monoclonal Antibody, in Patients with Moderate to Severe Plaque Psoriasis. Results of A 54-Week Randomized Double-Blind Placebo-Controlled PLANETA Clinical Trial / Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Bakulev, A.L. (Saratov State Medical University) ; Kokhan, M.M. (Ural Research Institute of Dermatovenerology and Immunopathology) ; Samtsov, A.V. (S. M. Kirov Military Medical Academy) ; Khairutdinov, V.R. (S. M. Kirov Military Medical Academy) ; Morozova, M.A. (JSC BIOCAD) ; Zolkin, N.A. (JSC BIOCAD) ; Kuryshev, I.V. (JSC BIOCAD) ; Petrov, A.N. (JSC BIOCAD) ; Artemeva, A.V. (JSC BIOCAD) ; Zinkina-Orikhan, A.V. (JSC BIOCAD)
Introduction: Netakimab (NTK), an original humanized anti-interleukin-17 monoclonal antibody, showed therapeutic efficacy in moderate-to-severe plaque psoriasis in a phase 2 clinical study. Herein we report the results of 54 weeks of a phase 3 PLANETA trial aimed to evaluate the efficacy and safety of two NTK regimens vs. [...]
2021 - 10.1007/s13555-021-00554-4
Dermatology and Therapy, Vol. 11 Núm. 4 (august 2021) , p. 1319-1332  
Detailed record - Creative Commons
2.
12 p, 1.1 MB The role of the interleukin-23/Th17 pathway in cardiometabolic comorbidity associated with psoriasis / Egeberg, A. (Gentofte Hospital) ; Gisondi, Paolo (University of Verona) ; Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Warren, R. B. (Manchester NIHR Biomedical Research Centre) ; Mrowietz, Ulrich (University Medical Center Schleswig-Holstein) ; Universitat Autònoma de Barcelona
Alterations in the innate and adaptive immunity underpin psoriasis pathophysiology, with the Th17 cells subset now recognized as the fundamental cells in the key controlling pathway involved in its pathogenesis. [...]
2020 - 10.1111/jdv.16273
Journal of the European Academy of Dermatology and Venereology, Vol. 34 (march 2020) , p. 1695-1706  
Detailed record - Creative Commons

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