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Resultats globals: 7 registres trobats en 0.02 segons.
Articles, 6 registres trobats
Documents de recerca, 1 registres trobats
Articles 6 registres trobats  
1.
17 p, 2.5 MB Acute Stress Regulates Sex-Related Molecular Responses in the Human Jejunal Mucosa : Implications for Irritable Bowel Syndrome / Rodiño-Janeiro, Bruno K. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Salvo-Romero, Eloísa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nieto Ruiz, Adoración (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Expósito, Elba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González Castro, Ana Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galan Soldevilla, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; de Torres, Inés (Universitat Autònoma de Barcelona. Departament de Medicina) ; Pribic, Teodora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lobo Álvarez, Beatriz (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Fortea, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gallart, Milagros (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pardo-Camacho, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guagnozzi, Danila (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Santos, Javier (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Alonso Cotoner, Carmen (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Universitat Autònoma de Barcelona
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder linked to intestinal barrier dysfunction and life stress. We have previously reported that female sex per se determines an increased susceptibility to intestinal barrier dysfunction after cold pain stress (CPS). [...]
2023 - 10.3390/cells12030423
Cells, Vol. 12 (january 2023)  
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2.
17 p, 2.2 MB The Local Activation of Toll-like Receptor 7 (TLR7) Modulates Colonic Epithelial Barrier Function in Rats / Estévez, Javier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Perea, Vicente (Universitat Autònoma de Barcelona. Institut de Neurociències)
Toll-like receptors (TLRs)-mediated host-bacterial interactions participate in the microbial regulation of gastrointestinal functions, including the epithelial barrier function (EBF). We evaluated the effects of TLR7 stimulation on the colonic EBF in rats. [...]
2023 - 10.3390/ijms24021254
International journal of molecular sciences, Vol. 24, Num. 2 (January 2023) , art. 1254  
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3.
16 p, 2.3 MB Effects of differently shaped TiONPs (nanospheres, nanorods and nanowires) on the in vitro model (Caco-2/HT29) of the intestinal barrier / García-Rodríguez, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vila, Laura (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Cortes Crignola, Constanza (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background:The biological effects of nanoparticles depend on several characteristics such as size and shape that must be taken into account in any type of assessment. The increased use of titanium dioxide nanoparticles (TiO2NPs) for industrial applications, and specifically as a food additive, demands a deep assessment of their potential risk for humans, including their abilities to cross biological barriers. [...]
2018 - 10.1186/s12989-018-0269-x
Particle and fibre toxicology, Vol. 15 (August 2018) , art. 33  
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4.
24 p, 1.4 MB Intestinal mucosal mast cells : key modulators of barrier function and homeostasis / Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron) ; Paracuellos, Irene (Hospital Universitari Vall d'Hebron) ; González Castro, Ana Maria (Hospital Universitari Vall d'Hebron) ; Rodríguez-Urrutia, Amanda (Universitat Autònoma de Barcelona) ; Rodríguez-Lagunas, María J. (Universitat de Barcelona) ; Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron) ; Santos, Javier (Hospital Universitari Vall d'Hebron) ; Vicario Perez, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The gastrointestinal tract harbours the largest opulation of mast cells in the body; this highly specialised leukocyte cell type is able to adapt its phenotype and function to the microenvironment in which it resides. [...]
2019 - 10.3390/cells8020135
Cells, Vol. 8 (2019) , p. 1-24  
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5.
14 p, 2.6 MB miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea / Martínez Martínez, Cristina (Hospital Universitari Vall d'Hebron) ; Rodiño-Janeiro, Bruno K. (Hospital Universitari Vall d'Hebron) ; Lobo Álvarez, Beatriz (Hospital Universitari Vall d'Hebron) ; Stanifer, Megan L. (University of Heidelberg) ; Klaus, Bernd (European Molecular Biology Laboratory (EMBL)) ; Granzow, Martin (Institute of Human Genetics, University of Heidelberg) ; González Castro, Ana Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Salvo-Romero, Eloisa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alonso Cotoner, Carmen (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron) ; Roeth, Ralph (nCounter Core Facility, Institute of Human Genetics, University of Heidelberg) ; Rappold, Gudrun (Institute of Human Genetics, University of Heidelberg) ; Huber, Wolfgang (European Molecular Biology Laboratory (EMBL)) ; González-Silos, Rosa (Institute of Medical Biometry and Informatics, University of Heidelberg) ; Lorenzo, Justo (Institute of Medical Biometry and Informatics, University of Heidelberg) ; Torres, Inés de (Hospital Universitari Vall d'Hebron) ; Azpiroz Vidaur, Fernando (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Boulant, Steeve (Research Group 'Cellular Polarity and Viral Infection' (F140), German Cancer Research Center (DKFZ)) ; Vicario, María (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Niesler, Beate (nCounter Core Facility, Institute of Human Genetics, University of Heidelberg) ; Santos, Javier (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network)
Micro-RNAs (miRNAs) play a crucial role in controlling intestinal epithelial barrier function partly by modulating the expression of tight junction (TJ) proteins. We have previously shown differential messenger RNA (mRNA) expression correlated with ultrastructural abnormalities of the epithelial barrier in patients with diarrhoea-predominant IBS (IBS-D). [...]
2017 - 10.1136/gutjnl-2016-311477
Gut, Vol. 66 (january 2017) , p. 1537-1538  
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6.
11 p, 972.3 KB Cellular and Molecular Basis of Intestinal Barrier Dysfunction in the Irritable Bowel Syndrome / Martínez Martínez, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González Castro, Ana Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vicario, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Santos, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
The etiopathogenesis of the irritable bowel syndrome (IBS), one of the most prevalent gastrointestinal disorders, is not well known. The most accepted hypothesis is that IBS is the result of the disturbance of the 'brain-gut axis. [...]
2012 - 10.5009/gnl.2012.6.3.305
Gut and Liver, Vol. 6 (july 2012) , p. 305-315  
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Documents de recerca 1 registres trobats  
1.
220 p, 2.2 MB El mastocito: célula clave en la microinflamación intestinal y en la regulación de la función barrera mediada por el estrés en el síndrome del intestino irritable con predominio de diarrea / Guilarte, Mar ; Santos Vicente, Francisco Javier, dir. ; Vicario Perez, Maria, dir. ; Bosch Gil, Josep Àngel, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
El Síndrome del Intestino Irritable (SII), clásicamente considerada una enfermedad del colon, es un trastorno altamente prevalente, con gran impacto en la calidad de vida y pocas opciones terapéuticas eficaces. [...]
Irritable Bowel Syndrome (IBS), classically considered a disease of the colon, is a highly prevalent disorder with significant impact on quality of life and few effective therapeutic options. Its etiology is unknown, but stress has been associated with the development and maintenance of IBS, based on the observation that affected patients suffer more chronic stress than the healthy population. [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2014  
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