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12 p, 2.4 MB |
DJ-1 administration exerts cardioprotection in a mouse model of acute myocardial infarction
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Gallinat, Alex (Universitat Autònoma de Barcelona) ;
Mendieta, Guiomar (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Padró, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Cardiovascular diseases, and particularly acute myocardial infarction (MI), are the most common causes of death worldwide. Infarct size is the major predictor of clinical outcomes in MI. The Parkinson's disease associated protein, DJ-1 (also known as PARK7), is a multifunctional protein with chaperone, redox sensing and mitochondrial homeostasis activities. [...]
2022 -  10.3389/fphar.2022.1002755
Frontiers in Pharmacology, Vol. 13 (September 2022) , p. 1002755
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41 p, 1.2 MB |
Therapeutic potential of emerging NAD+-increasing strategies for cardiovascular diseases
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Rotllan, Noemi (Institut d'Investigació Biomèdica Sant Pau) ;
Camacho, Mercedes (Institut d'Investigació Biomèdica Sant Pau) ;
Tondo, Mireia (Institut d'Investigació Biomèdica Sant Pau) ;
Diarte-Añazco, E. M. G. (Institut d'Investigació Biomèdica Sant Pau) ;
Canyelles, Marina (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Méndez Lara, Karen Alejandra (Institut d'Investigació Biomèdica Sant Pau) ;
Benitez, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Escolà-Gil, Joan Carles (Institut d'Investigació Biomèdica Sant Pau) ;
Blanco Vaca, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Julve i Gil, Josep (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Cardiovascular diseases are the leading cause of death worldwide. Aging and/or metabolic stress directly impact the cardiovascular system. Over the last few years, the contributions of altered nicotinamide adenine dinucleotide (NAD+) metabolism to aging and other pathological conditions closely related to cardiovascular diseases have been intensively investigated. [...]
2021 - 10.3390/antiox10121939
Antioxidants, Vol. 10 Núm. 12 (december 2021) , p. 1939
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13 p, 508.4 KB |
Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia : between bench and bedside
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Cabrera-Fuentes, H. A (Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey) ;
Alba-Alba, Corina (Institute of Genetics, Univeristy of the Sea. Puerto Escondido Campus, Oaxaca Oaxacan System of State Universities (SUNEO)) ;
Aragones, Julian (Instituto de Investigación Hospital Universitario de la Princesa) ;
Bernhagen, Jürgen (Institute of Biochemistry and Molecular Cell Biology, RWTH Aachen University) ;
Boisvert, William A. (Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii) ;
Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Cesarman-Maus, Gabriela (Department of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico) ;
Fleming, Ingrid (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, Frankfurt, Germany) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lecour, Sandrine (Hatter Institute and MRC Inter-University Cape Heart Unit, Faculty of Health Sciences, University of Cape Town) ;
Liehn, Elisa (Institute for Molecular Cardiovascular Research, RWTH University Hospital Aachen) ;
Marber, Michael S. (King's College London) ;
Marina, Nephtali (Department of Clinical Pharmacology, University College London) ;
Mayr, Manuel (King's College London. The James Black Centre) ;
Perez-Mendez, Oscar (Department of Molecular Biology, National Institute of Cardiology, Mexico City) ;
Miura, Tetsuji (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ;
Ruiz-Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Salinas-Estefanon, Eduardo M. (Laboratorio de Biofísica Cardiaca, Instituto de Fisiología, Universidad Autónoma de Puebla, Puebla, Mexico) ;
Ong, Sang-Bing (National Heart Research Institute Singapore, National Heart Centre Singapore) ;
Schnittler, Hans J. (Institute of Anatomy and Vascular Biology, Westfalian-Wilhelms-University, Münster) ;
Sanchez-Vega, Jose T. (Universidad Nacional Autónoma de México. Departamento de Microbiología y Parasitología) ;
Sumoza-Toledo, Adriana (Laboratorio Multidisciplinario de Ciencias Biomédicas, Instituto de Investigaciones Medico-Biológicas, Universidad Veracruzana campus Veracruz) ;
Vogel, Carl-Wilhelm (Department of Pathology, John A. Burns School of Medicine, University of Hawaii) ;
Yarullina, Dina (Department of Microbiology, Kazan Federal University, Kazan, Russian Federation) ;
Yellon, Derek M. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre) ;
Preissner, Klaus T. (Institute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany) ;
Hausenloy, Derek J. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre) ;
Universitat Autònoma de Barcelona
Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. [...]
2015 - 10.1007/s00395-015-0527-0
Basic Research in Cardiology, Vol. 111 (december 2015)
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