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9 p, 312.1 KB |
Head-to-Head Comparison of Three Vaccination Strategies Based on DNA and Raw Insect-Derived Recombinant Proteins against Leishmania
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Todolí, Felicitat (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Rodríguez-Cortés, Alhelí (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Núñez, María del Carmen (Universidad Politécnica de Madrid) ;
Laurenti, Márcia D. (Faculdade de Medicina da Universidade de São Paulo. Laboratorio Patologia de Moléstias Infecciosas) ;
Gómez-Sebastián, Silvia (Universidad Politécnica de Madrid) ;
Rodriguez, Fernando (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pérez-Martín, Eva (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Escribano, José M. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (Espanya)) ;
Alberola, Jordi (Alberola i Domingo) (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Parasitic diseases plague billions of people among the poorest, killing millions annually, and causing additional millions of disability-adjusted life years lost. Leishmaniases affect more than 12 million people, with over 350 million people at risk. [...]
2012 -  10.1371/journal.pone.0051181
PloS one, Vol. 7 (december 2012)
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14 p, 7.3 MB |
The effects of polyhexamethylene biguanide (PHMB) and TLR agonists alone or as polyplex nanoparticles against Leishmania infantum promastigotes and amastigotes
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Martínez-Orellana, Pamela (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Good, Liam (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ;
Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Baxarias, Marta (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Dogs are the main reservoir for Leishmania infantum, manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and immunomodulators are pursued. [...]
2020 - 10.3390/vetsci7040179
Veterinary Sciences, Vol. 7 Núm. 4 (2020) , p. 179
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4 p, 582.9 KB |
Canine leishmaniasis control in the context of one health
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Dantas-Torres, Filipe (Aggeu Magalhães Institute. Fundação Oswaldo Cruz (Fiocruz)) ;
Miró, Guadalupe (Universidad Complutense de Madrid) ;
Baneth, Gad (Hebrew University of Jerusalem) ;
Bourdeau, Patrick (Ecole Nationale Vétérinaire) ;
Breitschwerdt, Edward (North Carolina State University) ;
Capelli, Gioia (Istituto Zooprofilattico Sperimentale delle Venezie) ;
Cardoso, Luís (University of Trás-os-Montes e Alto Douro (UTAD)) ;
Day, Michael J. (Murdoch University) ;
Dobler, Gerhard (Bundeswehr Institute of Microbiology) ;
Ferrer, Luis (Universitat Autònoma de Barcelona) ;
Irwin, Peter (Murdoch University) ;
Jongejan, Frans (Utrecht University) ;
Kempf, Volkhard A. J. (Goethe-University) ;
Kohn, Barbara (Freie Universität Berlin) ;
Lappin, Michael R (Colorado State University) ;
Little, Susan (Oklahoma State University) ;
Madder, Maxime (Clinglobal) ;
Maggi, Ricardo (North Carolina State University) ;
Maia, Carla (Universidade NOVA de Lisboa) ;
Marcondes, Mary (São Paulo State University) ;
Naucke, Torsten (LABOKLIN GmbH) ;
Oliva, Gaetano (University of Naples Federico II) ;
Pennisi, Maria G. (University of Messina) ;
Penzhorn, Barend L. (University of Pretoria) ;
Peregrine, Andrew (University of Guelph) ;
Pfeffer, Martin (Universität Leipzig) ;
Roura, Xavier (Universitat Autònoma de Barcelona) ;
Sainz Rodríguez, Ángel (Universidad Complutense de Madrid) ;
Shin, SungShik (Chonnam National University) ;
Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Straubinger, Reinhard K. (Ludwig-Maximilians-Universität München) ;
Tasker, Séverine (University of Bristol) ;
Traub, Rebecca (University of Melbourne) ;
Wright, Ian (Mount Veterinary Practice) ;
Bowman, Dwight (Cornell University) ;
Gradoni, Luigi (Istituto Superiore di Sanità) ;
Otranto, Domenico (University of Bari Aldo Moro)
Dogs are the main reservoir of Leishmania infantum and in some countries have been regularly culled as part of government policy to control visceral leishmaniasis. At the 13th Symposium of the Companion Vector-Borne Diseases World Forum in Windsor, UK, March 19-22, 2018, we consolidated a consensus statement regarding the usefulness of dog culling as a means of controlling visceral leishmaniasis. [...]
2019 - 10.3201/eid2512.190164
Emerging Infectious Diseases, Vol. 25 Núm. 12 (2019) , p. E1-E4
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9 p, 1.1 MB |
Leishmania infantum-specific IFN-γ production in stimulated blood from cats living in areas where canine leishmaniosis is endemic
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Priolo, Vito (Università di Messina. Dipartimento di Scienze Veterinarie) ;
Martínez-Orellana, Pamela (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Pennisi, Maria Grazia (Università di Messina. Dipartimento di Scienze Veterinarie) ;
Masucci, Marisa (Università di Messina. Dipartimento di Scienze Veterinarie) ;
Prandi Chevalier, David (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Ippolito, Dorotea (Università di Messina. Dipartimento di Scienze Veterinarie) ;
Bruno, Federica (Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri. Centro di Referenza Nazionale per la Leishmaniosi (CReNaL)) ;
Castelli, Germano (Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri. Centro di Referenza Nazionale per la Leishmaniosi (CReNaL)) ;
Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Background: Feline leishmaniosis caused by Leishmania infantum is considered a rare disease in endemic areas, whereas subclinical infections are common. Immune response plays a key role in driving the course of L. [...]
2019 - 10.1186/s13071-019-3386-y
Parasites & vectors, Vol. 12 Núm. 1 (26 2019) , p. 133
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9 p, 623.9 KB |
Seroprevalence of canine Leishmania infantum infection in the Mediterranean region and identification of risk factors : The example of North-Eastern and Pyrenean areas of Spain
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Velez, R. (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Ballart, Cristina (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Domenech, E. (Hospital Veterinari Canis) ;
Abras, Alba (Universitat de Girona. Departament de Biologia) ;
Fernández-Arévalo, A. (Institut d'Investigació Biomèdica Sant Pau) ;
Ares Gómez, Sonia (Barcelona Institute for Global Health (ISGlobal)) ;
Tebar, Silvia (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Muñoz, C. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Cairó, J. (Hospital Veterinari Canis) ;
Gállego Culleré, M. (Montserrat) (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient)
The Mediterranean basin is an endemic region for canine leishmaniosis (CanL), where it represents a major veterinary problem and raises human health concerns. However, the distribution of the disease is heterogeneous and not all countries and locations have been equally studied and characterized. [...]
2019 - 10.1016/j.prevetmed.2018.10.015
Preventive Veterinary Medicine, Vol. 162 (january 2019) , p. 67-75
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6 p, 789.6 KB |
Associations between clinical canine leishmaniosis and multiple vector-borne co-infections : A case-control serological study
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Attipa, Charalampos (University of Liverpool. Department of Clinical Infection) ;
Solano Gallego, Laia. (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Leutenegger, Christian M. (IDEXX Laboratories) ;
Papasouliotis, Kostas (IDEXX Laboratories) ;
Soutter, Francesca (University of London. Department of Pathobiology and Population Sciences) ;
Balzer, Jörg (IDEXX GmbH) ;
Carver, Scott (University of Tasmania. Department of Biological Sciences) ;
Buch, Jesse S. (IDEXX Laboratories) ;
Tasker, Séverine (Linnaeus Group)
Background: Dogs that have clinical leishmaniosis (ClinL), caused by the parasite Leishmania infantum, are commonly co-infected with other pathogens, especially vector-borne pathogens (VBP). A recent PCR-based study found that ClinL dogs are more likely to be additionally infected with the rickettsial bacteria Ehrlichia canis. [...]
2019 - 10.1186/s12917-019-2083-6
BMC veterinary research, Vol. 15 Núm. 1 (18 2019) , p. 331
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5 p, 445.0 KB |
Canine leishmaniasis : the key points for qPCR result interpretation
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Martínez Díaz, Verónica Lucía (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Quilez Oliete, Javier (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Sánchez Bonastre, Armando (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Roura, Xavier (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari) ;
Francino, Olga (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Altet Sanahujes, Laura (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Background: Diagnosis and follow up of CanL is difficult since the range of clinical signs is varied and seroprevalence is high in endemic areas. The aims of this study were: i) demonstrate the advantages of Leishmania qPCR to diagnose and control CanL and highlight its prognostic value and ii) propose guidelines for tissue selection and infection monitoring. [...]
2011 - 10.1186/1756-3305-4-57
Parasites & vectors, Vol. 4, N. 57 (2011) , p. 1-5
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16 p, 7.5 MB |
LeishVet guidelines for the practical management of canine leishmaniosis
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Solano Gallego, Laia (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ;
Miró Corrales, Guadalupe (Universidad Complutense de Madrid. Departamento de Sanidad Animal) ;
Koutinas, Alek (Aristotle University of Thessaloniki (Grècia). Companion Animal Clinic) ;
Cardoso, Luís (Universidade de Trás-os-Montes e Alto Douro Dep. de Ciências Veterinárias (Portugal)) ;
Pennisi, Maria Grazia (Polo Universitario Annunziata (Messina, Itàlia). Dip.to Sanità Pubblica Veterinaria) ;
Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Bourdeau, Patrick (Ecole Nationale Veterinaire Agroalimentaire et de l'alimentation Nantes-Atlantique (França)) ;
Oliva, Gaetano (University of Naples Federico II (Itàlia). Dep. of Veterinary Clinical Sciences) ;
Baneth, Gad (Hebrew University. School of Veterinary Medicine)
The LeishVet group has formed recommendations designed primarily to help the veterinary clinician in the management of canine leishmaniosis. The complexity of this zoonotic infection and the wide range of its clinical manifestations, from inapparent infection to severe disease, make the management of canine leishmaniosis challenging. [...]
2011 - 10.1186/1756-3305-4-86
Parasites & vectors, Vol. 4, N. 86 (2011) , p. 1-16
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6 p, 163.5 KB |
Detection of Leishmania infantum DNA mainly in Rhipicephalus sanguineus male ticks removed from dogs living in endemic areas of canine leishmaniosis
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Solano Gallego, Laia (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ;
Rossi, Luca (Clinica Veterinaria Corridori-Rossi-Marioni (Grosseto, Itàlia)) ;
Scroccaro, Anna M. (Laboratorio e Clinica Veterinari San Marco (Pàdua, Itàlia)) ;
Montarsi, Fabrizio (Istituto Zooprofilattico Sperimentale delle Venezie. Dipartimento di Ecopatologia (Pàdua, Itàlia)) ;
Caldin, Marco (Laboratorio e Clinica Veterinari San Marco (Pàdua, Itàlia)) ;
Furlanello, Tommaso (Laboratorio e Clinica Veterinari San Marco (Pàdua, Itàlia)) ;
Trotta, Michele (Laboratorio e Clinica Veterinari San Marco (Pàdua, Itàlia))
Background: Sand flies are the only biologically adapted vectors of Leishmania parasites, however, a possible role in the transmission of Leishmania has been proposed for other hematophagous ectoparasites such as ticks. [...]
2012 - 10.1186/1756-3305-5-98
Parasites & vectors, Vol. 5, N. 98 (2012) , p. 1-6
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