Home > Search Results: Lipid A
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Results overview: Found 4 records in 0.03 seconds.
Articles, 4 records found
Articles 4 records found  
1.
13 p, 5.3 MB Biotechnological production of the cell penetrating antifungal PAF102 peptide in pichia pastoris / Popa, Crina (Centre de Recerca en Agrigenòmica) ; Shi, Xiaoqing (Centre de Recerca en Agrigenòmica) ; Ruiz Medina, Tarik (Centre de Recerca en Agrigenòmica) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Coca López, María (Centre de Recerca en Agrigenòmica)
Antimicrobial peptides (AMPs) have potent and durable antimicrobial activity to a wide range of fungi and bacteria. The growing problem of drug-resistant pathogenic microorganisms, together with the lack of new effective compounds, has stimulated interest in developing AMPs as anti-infective molecules. [...]
2019 - 10.3389/fmicb.2019.01472
Frontiers in microbiology, Vol. 10 (June 2019) , art. 1472  
Detailed record - Creative Commons
2.
15 p, 3.4 MB Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins / Mamat, Uwe (Forschungszentrum Borstel) ; Wilke, Kathleen (Forschungszentrum Borstel) ; Bramhill, David (Research Corporation Technologies (Tucson)) ; Schromm, Andra Beate (Forschungszentrum Borstel) ; Lindner, Buko (Forschungszentrum Borstel) ; Kohl, Thomas Andreas (Forschungszentrum Borstel) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Schaffer, Lana (Scripps Research Institute) ; Head, Steven Robert (Scripps Research Institute) ; Souvignier, Chad (Research Corporation Technologies (Tucson)) ; Meredith, Timothy Charles (Pennsylvania State University. Department of Biochemistry and Molecular Biology) ; Woodard, Ronald Wesley (Bramhill Biological Consulting)
Background: lipopolysaccharide (LPS), also referred to as endotoxin, is the major constituent of the outer leaflet of the outer membrane of virtually all Gram-negative bacteria. The lipid A moiety, which anchors the LPS molecule to the outer membrane, acts as a potent agonist for Toll-like receptor 4/myeloid differentiation factor 2-mediated pro-inflammatory activity in mammals and, thus, represents the endotoxic principle of LPS. [...]
2015 - 10.1186/s12934-015-0241-5
Microbial cell factories, Vol. 14, Issue 57 (2015)  
Detailed record - Creative Commons
3.
11 p, 2.3 MB JNK and ceramide kinase govern the biogenesis of lipid droplets through activation of group IVA phospholipase A2 / Gubern Burset, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barceló Torns, Miquel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barneda, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Chalfant, Charles E. (Virginia Commonwealth University. School of Medicine) ; Balsinde, Jesús (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología y Genética Molecular) ; Balboa María, A. (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología y Genética Molecular) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The biogenesis of lipid droplets (LD) induced by serum depends on group IVA phospholipase A2 (cPLA2α). This work dissects the pathway leading to cPLA2α activation and LD biogenesis. Both processes were Ca2+-independent, as they took place after pharmacological blockade of Ca2+ transients elicited by serum or chelation with 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester). [...]
2009 - 10.1074/jbc.M109.061515
Journal of biological chemistry, Vol. 284, Num. 47 (2009) , p. 32359-32369  
Detailed record -
4.
12 p, 853.4 KB Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2 / Gubern Burset, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barceló Torns, Miquel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Casas, Javier (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología y Genética Molecular) ; Barneda, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Balsinde, Jesús (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología y Genética Molecular) ; Balboa María, A. (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología y Genética Molecular) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
This work investigates the metabolic origin of triacylglycerol (TAG) formed during lipid droplet (LD) biogenesis induced by stress. Cytotoxic inhibitors of fatty acid synthase induced TAG synthesis and LD biogenesis in CHO-K1 cells, in the absence of external sources of fatty acids. [...]
2009 - 10.1074/jbc.M806173200
Journal of biological chemistry, Vol. 284, Num. 9 (2009) , p. 5697-56708  
Detailed record -

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