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Resultats globals: 3 registres trobats en 0.02 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
15 p, 2.0 MB Basic Properties of the p38 Signaling Pathway in Response to Hyperosmotic Shock / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Some properties of signaling systems, like ultrasensitivity, hysteresis (a form of biochemical memory), and all-or-none responses at a single cell level, are important to understand the regulation of irreversible processes. [...]
2015 - 10.1371/journal.pone.0135249
PloS one, Vol. 10, Num. 9 (September 2015) , p. 1-15  
Registre complet - Creative Commons
2.
16 p, 1.8 MB Interleukin-10 enhances the intestinal epithelial barrier in the presence of corticosteroids through p38 MAPK activity in Caco-2 monolayers : a possible mechanism for steroid responsiveness in ulcerative colitis / Lorén Moreno, Violeta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cabré i Gelada, Eduard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ojanguren, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domènech, Eugeni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pedrosa Tapias, Elisabet (Institut Germans Trias i Pujol) ; Garcia-Jaraquemada, Arce (Institut Germans Trias i Pujol) ; Mañosa i Ciria, Míriam (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Manyé Almero, Josep (Institut Germans Trias i Pujol)
Glucocorticosteroids are the first line therapy for moderate-severe flare-ups of ulcerative colitis. Despite that, up to 60% of patients do not respond adequately to steroid treatment. Previously, we reported that low IL-10 mRNA levels in intestine are associated with a poor response to glucocorticoids in active Crohn's disease. [...]
2015 - 10.1371/journal.pone.0130921
PloS one, Vol. 10, No 6 (June 2015) , p. e0130921  
Registre complet - Creative Commons
3.
9 p, 1.4 MB Prostaglandin E2 Prevents Hyperosmolar-Induced Human Mast Cell Activation through Prostanoid Receptors EP2 and EP4 / Torres Atencio, Ivonne Marisol (Universidad de Panamá. Facultad de Medicina) ; Ainsua-Enrich, Erola (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Mora Pérez, Fernando de (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Picado Valles, César (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Martín Castillo, Margarita (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Background: Mast cells play a critical role in allergic and inflammatory diseases, including exercise-induced bronchoconstriction (EIB) in asthma. The mechanism underlying EIB is probably related to increased airway fluid osmolarity that activates mast cells to the release inflammatory mediators. [...]
2014 - 10.1371/journal.pone.0110870
PloS one, Vol. 9, Issue 10 (October 2014) , p.e110870  
Registre complet - Creative Commons

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