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5 p, 414.7 KB |
Long-term impact of ixekizumab on psoriasis itch severity : Results from a phase III clinical trial and long-term extension
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Kimball, Alexandra B. (Beth Israel Deaconess Hospital and Harvard Medical School) ;
Luger, Thomas (University of Muenster) ;
Gottlieb, Alice (New York Medical College) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Kaufmann, Roland (Goethe University) ;
Burge, Russel (University of Cincinnati) ;
Lin, Chen-Yen (Eli Lilly and Company) ;
Yosipovitch, Gil (University of Miami Miller School Of Medicine) ;
Universitat Autònoma de Barcelona
Itching is a prevalent plaque psoriasis symptom. Ixekizumab, an IL-17A antagonist, has demonstrated rapid, significant improvements in itch severity over 12 weeks in Phase III psoriasis trials (UNCOVER-1, UNCOVER-2). [...]
2018 -  10.2340/00015555-2801
Acta dermato-venereologica, Vol. 98 Núm. 1 (2018) , p. 98-102
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8 p, 692.3 KB |
Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma : Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment
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Reinoso-Segura, Marta (Universidad de Sevilla) ;
Caballero Velazquez, Teresa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Herrera, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Patriarca, Francesca (University Hospital and DAME) ;
Fanin, Renato (University Hospital and DAME) ;
Bruno, Benedetto (AOU Città della Salute e della Scienza) ;
Einsele, Hermann (Medizinische Klinik and Poliklinik II University Hospital) ;
Nahi, Hareth (Karolinska University Hospital) ;
Granell, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
López-Corral, Lucía (Centro de Investigación del Cáncer-IBMCC) ;
Reguera, Juan L. (Universidad de Sevilla) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Gahrton, Gösta (European Society for Blood and Marrow Transplantation) ;
Pérez-Simón, José A. (Universidad de Sevilla) ;
Universitat Autònoma de Barcelona
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after allogeneic stem cell transplantation (alloSCT). In contrast, disease relapse remains the most frequent cause of treatment failure and death. [...]
2022 - 10.1016/j.jtct.2022.01.026
Transplantation and Cellular Therapy, Vol. 28 Núm. 5 (may 2022) , p. 258.e1-258.e8
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15 p, 1.9 MB |
Can the Addition of Maintenance Electroconvulsive Therapy to Pharmacotherapy Improve Relapse Prevention in Severe Major Depressive Disorder? A Randomized Controlled Trial
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Martínez-Amorós, Erika (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cardoner, N. (Narcís) (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Gálvez, Verònica (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
De Arriba-Arnau, Aida (Hospital Universitari de Bellvitge) ;
Soria, Virginia (Hospital Universitari de Bellvitge) ;
Palao, Diego Jose (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Menchón, José M. (Hospital Universitari de Bellvitge) ;
Urretavizcaya, Mikel (Hospital Universitari de Bellvitge)
Few systematic evaluations have been performed of the efficacy of electroconvulsive therapy (ECT) as a relapse prevention strategy in major depressive disorder (MDD). This is a single-blind, multicenter, randomized controlled trial to compare the efficacy and tolerability of pharmacotherapy plus maintenance ECT (M-Pharm/ECT) versus pharmacotherapy alone (M-Pharm) in the prevention of MDD relapse. [...]
2021 - 10.3390/brainsci11101340
Brain sciences, Vol. 11 (october 2021)
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16 p, 2.1 MB |
Recent therapeutic advances in urothelial carcinoma : A paradigm shift in disease management
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Bellmunt, J. (Department of Medical Oncology. Beth Israel Deaconess Medical Center and IMIM-PSMAR Lab. Harvard Medical School) ;
Valderrama, B.P. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Puente, J. (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Grande, Enrique (MD Anderson Cancer Center Madrid) ;
Bolós, M.V. (Pfizer) ;
Laínez, Nuria (Hospital Universitario de Navarra) ;
Vázquez, S. (Hospital Universitario Lucus Augusti (Lugo)) ;
Maroto Rey, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Climent, Miguel Ángel (Department of Medical Oncology. Valencia Institute of Oncology Foundation) ;
Garcia del Muro, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Arranz, J.Á. (Hospital General Universitario Gregorio Marañón) ;
Durán, Ignacio (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Universitat Autònoma de Barcelona
Management of first-line advanced urothelial carcinoma (UC) has consisted during the past three decades in the administration of platinum-based chemotherapy followed by observation. Despite moderate to high response rates to first-line treatment, most patients will relapse shortly after and the outcomes with subsequent therapies are poor with 5-year overall survival rates of 5% in the pre-immunotherapy era. [...]
2022 - 10.1016/j.critrevonc.2022.103683
Critical Reviews in Oncology/Hematology, Vol. 174 (june 2022) , p. 103683
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13 p, 254.3 KB |
First-line maintenance treatment in metastatic colorectal cancer (mCRC) : Quality and clinical benefit overview
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Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Tobeña, M. (Quironsalud Hospital)
Different strategies of maintenance therapy (sequential CT, intermittent CT, intermittent CT and MAbs, or de-escalation MAbs monotherapy) after first-line treatment are undertaken. Many randomized clinical trials (RCT), which evaluated these approaches, suffer from incorrect design, heterogenous primary endpoints, inadequate size, and other methodology flaws. [...]
2021 - 10.3390/jcm10030470
Journal of clinical medicine, Vol. 10 Núm. 3 (january 2021) , p. 1-13
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6 p, 668.6 KB |
Theoretical frameworks and approaches used within the Reserve, Resilience and Protective Factors professional interest area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment
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Bartrés-Faz, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Arenaza-Urquijo, Eider (Pasqual Maragall Foundation) ;
Ewers, Michael (LMU Munich. University Hospital) ;
Belleville, Sylvie (Université de Montréal) ;
Chételat, G. (Normandie University) ;
Franzmeier, Nicolai (LMU Munich. University Hospital) ;
Gonneaud, Julie (McGill University) ;
de Echevarri, José María González (Pasqual Maragall Foundation) ;
Okonkwo, Ozioma (University of Wisconsin-Madison) ;
Schultz, Stephanie (University of Wisconsin-Madison) ;
Valenzuela, Michael (University of New South Wales) ;
Stern, Yaakov (Columbia University) ;
Vemuri, Prashanthi (Mayo Clinic Rochester Minnesota)
Reserve, resilience, maintenance, and related concepts are intensely debated in aging and Alzheimer's disease research. Through a short survey, we gathered information about theoretical concepts and methodologies used among research groups of the Reserve, Resilience, and Protective Factors Professional Interest Area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment. [...]
2020 - 10.1002/dad2.12115
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 12 (november 2020)
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17 p, 180.2 KB |
Arqueología, economía, mujeres y hombres. Producción de sujetos y su mantenimiento en las sociedades ágrafas andinas
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Escoriza-Mateu, Trinidad (Universidad de Almería. Departamento de Geografía, Historia y Humanidades) ;
Castro Martínez, Pedro V. (Pedro Vicente) (Universitat Autònoma de Barcelona. Departament de Prehistòria)
En este trabajo pretendemos señalar la importancia económica que las actividades de "cuidados y atenciones" hacia los sujetos sociales, las Mujeres y los Hombres, tienen para la reproducción de la vida social. [...]
We emphasize the economic importance of the activities of "care and attention" for the production and maintenance of social life. From a Feminist and Materialist perspective this activities are work, and part of the social production: this is Subjects Maintenance Production. [...]
2012
Claroscuro. Revista del Centro de Estudios sobre Diversidad Cultural, Núm. 11 (2012) , p. 66-82
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7 p, 539.8 KB |
Quality of life and well-being from the perspective of patients on opioid agonist maintenance treatment : study protocol for a systematic review of qualitative research and a scoping review of measures
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Solà, Ivan (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Trujols, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Ribalta, Elisa (Institut d'Investigació Biomèdica Sant Pau) ;
Alcaraz Garcia, Saül (Institut d'Investigació Biomèdica Sant Pau) ;
Robleda, Gemma (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Selva Olid, Clara (Universitat Autònoma de Barcelona. Departament de Psicologia Social) ;
Pérez de los Cobos, José (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Universitat Autònoma de Barcelona
Opioid agonist maintenance treatment (OAMT) is a first-line treatment for heroin dependence, but its effectiveness has been assessed primarily through clinical outcomes with a limited attention to patient perspectives. [...]
2019 - 10.1186/s13643-019-1237-8
Systematic Reviews, Vol. 8 (december 2019)
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28 p, 1007.8 KB |
Las producciones cerámicas argáricas : entre la vida cotidiana y la muerte anda el juego
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Alarcón García, Eva (Universidad de Granada. Departamento de Prehistoria y Arqueología)
Las producciones cerámicas prehistóricas han sido, son y serán una fuente de información inigualable de las sociedades de nuestro pasado. En este trabajo se presentan los estudios realizados, desde una perspectiva de la arqueología feminista, de género y edad, de los recipientes cerámicos del sureste peninsular adscritos a la cultura del Argar. [...]
Les produccions ceràmiques prehistòriques han estat, són i seran una font d'informació inigualable de les societats del nostre passat. En aquest treball es presenten els estudis fets, des d'una perspectiva de l'arqueologia feminista, de gènere i edat, dels recipients ceràmics del sud-est peninsular adscrits a la cultura de l'Argar. [...]
Prehistoric ceramic productions have been, are and will be a source of unmatched information from our past societies. This paper explores, from a feminist archaeology perspective, the argaric ceramic vessels of the southeast of the Iberian Peninsula in relation to gender and age. [...]
2019 - 10.5565/rev/tda.102
Treballs d'arqueologia, Vol. 23 (2019) , p. 283-309 (Articles)
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