Home > Search Results: Major histocompatibility complex
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Results overview: Found 6 records in 0.02 seconds.
Articles, 5 records found
Research literature, 1 records found
Articles 5 records found  
1.
4 p, 265.6 KB Epigenetic therapies for neuroblastoma : immunogenicity awakens / Jiménez Jiménez, Carlos (Human Technopole) ; Moreno, Lucas (Hospital Universitari Vall d'Hebron) ; Segura, Miguel F. (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
The development of immunotherapies for neuroblastoma remains challenging owing to the low immunogenicity of neuroblastoma cells, as reflected by the low expression of one of the main triggers of immune recognition, the major histocompatibility complex class I (MHC-I). [...]
2023 - 10.1002/1878-0261.13404
Molecular Oncology, Vol. 17 (march 2023) , p. 718-721  
Detailed record - Creative Commons
2.
9 p, 1.1 MB Hidden MHC genetic diversity in the Iberian ibex (Capra pyrenaica) / Angelone, Samer ; Jowers, Michael J. (Campus Agrario De Vairão) ; Molinar Min, Anna Rita ; Fandos, Paulino ; Prieto, Paloma (Parque Natural Sierras de Cazorla, Segura y Las Villas) ; Pasquetti, Mario ; Cano-Manuel, Francisco Javier (Espacio Natural Sierra Nevada) ; Mentaberre García, Gregorio (Universitat Autònoma de Barcelona) ; López Olvera, Jorge R. (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ; Ráez-Bravo, Arián ; Espinosa, José ; Pérez Jiménez, Jesús María ; Soriguer, Ramón C. ; Rossi, Luca ; Granados Torres, José Enrique (Espacio Natural Sierra Nevada)
Defining hidden genetic diversity within species is of great significance when attempting to maintain the evolutionary potential of natural populations and conduct appropriate management. Our hypothesis is that isolated (and eventually small) wild animal populations hide unexpected genetic diversity due to their maintenance of ancient polymorphisms or introgressions. [...]
2018 - 10.1186/s12863-018-0616-9
BMC genetics, Vol. 19 (may 2018)  
Detailed record - Creative Commons
3.
3 p, 171.7 KB Restricted dog leucocyte antigen (DLA) class II haplotypes and genotypes in Beagles / Soutter, Francesca (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ; Kennedy, Lorna J. (Centre for Integrated Genomic Medical Research, University of Manchester) ; Ollier, William E. R. (Centre for Integrated Genomic Medical Research, University of Manchester) ; Solano Gallego, Laia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Catchpole, Brian (University of London. Royal Veterinary College (Hatfield, Regne Unit))
Beagles are commonly used in vaccine trials as part of the regulatory approval process. Genetic restriction within this breed and the impact this might have on vaccine responses are rarely considered. [...]
2015 - 10.1016/j.tvjl.2014.12.032
The veterinary journal, Vol. 203 (march 2015) , p. 345-347  
Detailed record - Creative Commons
4.
15 p, 240.3 KB Mate choice for neutral and MHC genetic characteristics in Alpine marmots : different targets in different contexts? / Ferrandiz-Rovira, Mariona (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Allainé, Dominique (Centre national de la recherche scientifique (França). Laboratoire Biométrie et Biologie Evolutive) ; Callait-Cardinal, Marie-Pierre (Centre national de la recherche scientifique (França). Laboratoire Biométrie et Biologie Evolutive) ; Cohas, Aurélie (Centre national de la recherche scientifique (França). Laboratoire Biométrie et Biologie Evolutive)
Sexual selection through female mate choice for genetic characteristics has been suggested to be an important evolutionary force maintaining genetic variation in animal populations. However, the genetic targets of female mate choice are not clearly identified and whether female mate choice is based on neutral genetic characteristics or on particular functional loci remains an open question. [...]
2016 - 10.1002/ece3.2189
Ecology and evolution, Vol. 6, issue 13 (July 2016) , p. 4243-4257
4 documents
Detailed record - Creative Commons
5.
21 p, 2.1 MB Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat / Tuncel, Jonatan (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Haag, Sabrina (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Yau, Anthony C. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Norin, Ulrika (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Baud, Amelie (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Lönnblom, Erik (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Maratou, Klio (Imperial College London) ; Ytterberg, A. Jimmy (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Ekman, Diana (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Thordardottir, Soley (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Johannesson, Martina (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Gillett, Alan (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Stridh, Pernilla (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Jagodic, Maja (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Olsson, Tomas (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Zubarev, Roman (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Mott, Richard (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Aitman, Timothy J. (Imperial College London) ; Flint, Jonathan (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Holmdahl, Rikard (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; EURATRANS Consortium
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. [...]
2014 - 10.1371/journal.pgen.1004151
PLoS Genetics, Vol. 10 Issue 2 (February 2014) , p. e1004151  
Detailed record - Creative Commons

Research literature 1 records found  
1.
1 p, 5.1 MB Analysis of the latest pan-specific bioinformatic tools for the discovery of MHC class II binding epitopes / Puigdomènech Gómez, Héctor ; Yero, Daniel, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Performance of bioinformatic approaches to discover HLA-II binding epitopes is still far from best. HLA-II polymorphism lead to the creation of the so-called pan-specific tools, which are able to predict binding epitopes for MHC alleles without previous affinity data. [...]
2016
Grau en Genètica [833]  
Detailed record - Creative Commons

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