Resultats globals: 25 registres trobats en 0.02 segons.
Articles, 18 registres trobats
Documents de recerca, 7 registres trobats
Articles 18 registres trobats  1 - 10següent  anar al registre:
1.
15 p, 2.0 MB MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression / Toll, Agustí (Institut Hospital del Mar d'Investigacions Mèdiques) ; Salgado, Rocío (Hospital del Mar (Barcelona)) ; Espinet, Blanca (Hospital del Mar (Barcelona)) ; Díaz-Lagares, Angel (Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Spain) ; Hernández-Ruiz, Eugenia (Hospital Universitari Vall d'Hebron) ; Andrades, Evelyn (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sandoval, Juan (Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Spain) ; Esteller, Manel (Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia Spain) ; Pujol, Ramón M (Hospital del Mar (Barcelona)) ; Hernández-Muñoz, Inmaculada (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and frequently progresses from an actinic keratosis (AK), a sun-induced keratinocyte intraepithelial neoplasia (KIN). Epigenetic mechanisms involved in the phenomenon of progression from AK to cSCC remain to be elicited. [...]
2016 - 10.1186/s12943-016-0537-z
Molecular Cancer, Vol. 15 (july 2016)  
2.
21 p, 2.4 MB Differential DNA methylation of vocal and facial anatomy genes in modern humans / Gokhman, David (The Hebrew University of Jerusalem. The Alexander Silberman Institute of Life Sciences. Department of Genetics (Israel)) ; Nissim-Rafinia, Malka (The Hebrew University of Jerusalem. The Alexander Silberman Institute of Life Sciences. Department of Genetics (Israel)) ; Agranat-Tamir, Lily (The Hebrew University of Jerusalem. Department of Statistics (Israel)) ; Housman, Genevieve (Arizona State University. Center for Evolution and Medicine (USA)) ; García-Pérez, Raquel (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Lizano, Esther (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Cheronet, Olivia (University of Vienna. Department of Evolutionary Anthropology (Austria)) ; Mallick, Swapan (Howard Hughes Medical Institute. Harvard Medical School (USA)) ; Nieves-Colón, Maria A. (Arizona State University. Center for Evolution and Medicine (USA)) ; Li, Heng (Broad Institute (USA)) ; Alpaslan-Roodenberg, Songül (Harvard Medical School. Department of Genetics (USA)) ; Novak, Mario (University College Dublin. Earth Institute and School of Archaeology (Ireland)) ; Gu, Hongcang (Broad Institute (USA)) ; Osinski, Jason M. (University at Buffalo. Jacobs School of Medicine and Biomedical Sciences. Department of Biochemistry (USA)) ; Ferrando-Bernal, Manuel (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Gelabert, Pere (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Lipende, Iddi (Jane Goodall Institute. Gombe Stream Research Center (Tanzania)) ; Mjungu, Deus (Jane Goodall Institute. Gombe Stream Research Center (Tanzania)) ; Kondova, Ivanela (Biomedical Primate Research Centre (Netherlands)) ; Bontrop, Ronald (Biomedical Primate Research Centre (Netherlands)) ; Kullmer, Ottmar (Senckenberg Center of Human Evolution and Paleoecology. Department of Palaeoanthropology and Messel Research (Germany)) ; Weber, Gerhard (University of Vienna. Department of Evolutionary Anthropology (Austria)) ; Shahar, Tal (Shaare Zedek Medical Center. Department of Neurosurgery (Israel)) ; Dvir-Ginzberg, Mona (Hebrew University of Jerusalem. Institute of Dental Sciences. Laboratory of Cartilage Biology (Israel)) ; Faerman, Marina (Hebrew University of Jerusalem. Institute of Dental Sciences. Laboratory of Bioanthropology and Ancient DNA (Israel)) ; Quillen, Ellen E. (Texas Biomedical Research Institute. Department of Genetics (USA)) ; Meissner, Alexander (Harvard University. Department of Stem Cell and Regenerative Biology (USA)) ; Lahav, Yonatan (The Hebrew University Medical School (Israel)) ; Kandel, Leonid (Hadassah - Hebrew University Medical Center. Orthopaedic Department (Israel)) ; Liebergall, Meir (Hadassah - Hebrew University Medical Center. Orthopaedic Department (Israel)) ; Prada, María E. (I.E.S.O. 'Los Salados'. Junta de Castilla y León) ; Vidal, Julio M. (Junta de Castilla y León. Servicio de Cultura de León) ; Gronostajski, Richard M. (University at Buffalo. Jacobs School of Medicine and Biomedical Sciences. Department of Biochemistry (USA)) ; Stone, Anne C. (Arizona State University. Institute of Human Origins (USA)) ; Yakir, Benjamin (The Hebrew University of Jerusalem. Department of Statistics (Israel)) ; Lalueza-Fox, Carles (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Pinhasi, Ron (University of Vienna. Department of Evolutionary Anthropology (Austria)) ; Reich, David (Howard Hughes Medical Institute. Harvard Medical School (USA)) ; Marques-Bonet, Tomas (Institut Català de Paleontologia Miquel Crusafont) ; Meshorer, Eran (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences (Israel)) ; Carmel, Liran (The Hebrew University of Jerusalem. The Alexander Silberman Institute of Life Sciences. Department of Genetics (Israel))
Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challenging. [...]
2020 - 10.1038/s41467-020-15020-6
Nature communications, Vol. 11 (March 2020) , art. 1189  
3.
Epigenetic differences in the innate response after immune stimulation during zebrafish sex differentiation / Moraleda-Prados, J. (Institut de Ciències del Mar - CSIC) ; Caballero-Huertas, M. (Institut de Ciències del Mar - CSIC) ; Valdivieso, A. (Institut de Ciències del Mar - CSIC) ; Joly, S. (Institut de Ciències del Mar - CSIC) ; Ji, Jie (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Roher Armentia, Nerea (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ribas, L. (Institut de Ciències del Mar - CSIC)
Infections are able to trigger epigenetic modifications; however, epigenetic-mediating infections in the immune system in fish is currently unavailable. Within this purpose, zebrafish were immune-stimulated with three lipopolysaccharides (LPS) during sex differentiation. [...]
2021 - 10.1016/j.dci.2020.103848
Developmental and Comparative Immunology, Vol. 114 (January 2021) , art. 103848  
4.
8 p, 1.6 MB DNA methylation of MMPs and TIMPs in atherothrombosis process in carotid plaques and blood tissues / Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Cullell, Natalia (Institut d'Investigació Biomèdica Sant Pau) ; Soriano-Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Carrera, Caty (Institut d'Investigació Biomèdica Sant Pau) ; Torres-Aguila, Nuria P. (Institut d'Investigació Biomèdica Sant Pau) ; Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; de Moura, Manuel Castro (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Spain) ; Fernández-Sanlés, Alba (Cardiovascular Epidemiology and Genetics Research Group, Hospital del Mar Medical Research Institute, Universitat Pompeu Fabra, Barcelona, Spain) ; Esteller, Manel (Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Spain) ; Elosua, Roberto (Cardiovascular Epidemiology and Genetics Research Group, Hospital del Mar Medical Research Institute, Universitat Pompeu Fabra, Barcelona, Spain) ; Jiménez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Krupinski, Jerzy (* These authors contributed equally to this work) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Background and Purpose: Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to atheromatous plaques and ischemic stroke, while no studies of DNA methylation (DNAm) patterns of MMP or TIMP have been performed to that end. [...]
2020 - 10.18632/oncotarget.27469
Oncotarget, Vol. 11 (march 2020) , p. 905-912  
5.
28 p, 1.0 MB Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins / Sánchez Huertas, César (Institut Català de Nanociència i Nanotecnologia) ; Aviñó, Anna (Institut de Química Avançada de Catalunya) ; Kurachi, Cristina (Institut Català de Nanociència i Nanotecnologia) ; Piqué, Albert (Institut Català de Nanociència i Nanotecnologia) ; Sandoval, Juan (Institut de Recerca Biomèdia Bellvitge) ; Eritja, Ramon (Institut de Química Avançada de Catalunya) ; Esteller, Manel (Institucio Catalana de Recerca i Estudis Avançats (ICREA)) ; Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
Cancer diagnosis continuously evolves due to the better understanding of tumorigenic processes. DNA-methylation is consolidated as an effective biomarker for cancer prognosis and diagnostic even in tumors of unknown origin. [...]
2018 - 10.1016/j.bios.2018.08.027
Biosensors and bioelectronics, Vol. 120 (November 2018) , p. 47-54  
6.
60 p, 1.6 MB The Physcomitrella patens chromosome-scale assembly reveals moss genome structure and evolution / Lang, Daniel (Helmholtz Center Munich. Plant Genome and Systems Biology) ; Ullrich, Kristian K. (University of Marburg. Faculty of Biology) ; Murat, Florent (Institut national de la recherche agronomique. UMR 1095 Genetics. Diversity and Ecophysiology of Cereals) ; Fuchs, Jorg (Leibniz Institute of Plant Genetics and Crop Plant Research) ; Jenkins, Jerry (HudsonAlpha Institute for Biotechnology) ; Haas, Fabian B. (University of Marburg. Faculty of Biology) ; Piednoel, M. (Max Planck Institute for Plant Breeding Research) ; Gundlach, H. (Helmholtz Center Munich. Plant Genome and Systems Biology) ; Van Bel, M. (VIB-UGent Center for Plant Systems Biology) ; Meyberg, R. (University of Marburg. Faculty of Biology) ; Vives, Cristina (Centre de Recerca en Agrigenòmica) ; Morata, Jordi (Centre de Recerca en Agrigenòmica) ; Symeonidi, Aikaterini (University of Marburg. Faculty of Biology) ; Hiss, Manuel (University of Marburg. Faculty of Biology) ; Muchero, Wellington (Oak Ridge National Laboratory. Biosciences Division) ; Kamisugi, Yasuko (University of Leeds. Centre for Plant Sciences) ; Saleh, Omar (University of Freiburg. Faculty of Biology) ; Blanc, Guillaume (Aix-Marseille Université. Structural and Genomic Information Laboratory) ; Decker, Eva L. (University of Freiburg. Faculty of Biology) ; van Gessel, Nico (University of Freiburg. Faculty of Biology) ; Grimwood, Jane (HudsonAlpha Institute for Biotechnology) ; Hayes, Richard D. (DOE Joint Genome Institute) ; Graham, Sean W. (University of British Columbia. Department of Botany) ; Gunter, Lee E. (Oak Ridge National Laboratory. Biosciences Division) ; McDaniel, Stuart F. (University of Florida. Department of Biology) ; Hoernstein, Sebastian N.W. (University of Freiburg. Faculty of Biology) ; Larsson, Anders (Uppsala University. Evolutionary Biology Centre) ; Li, Fay-Wei (Boyce Thompson Institute) ; Perroud, Pierre-François (University of Marburg. Faculty of Biology) ; Phillips, Jeremy (DOE Joint Genome Institute) ; Ranjan, Priya (Oak Ridge National Laboratory) ; Rokshar, Daniel S. (DOE Joint Genome Institute) ; Rothfels, Carl J. (University of California. Department of Integrative Biology) ; Schneider, Lucas (University of Marburg. Faculty of Biology) ; Shu, Shengqiang (DOE Joint Genome Institute) ; Stevenson, Dennis W. (New York Botanical Garden) ; Thümmler, Fritz (Vertis Biotechnologie AG) ; Tillich, Michael (Max Planck Institute of Molecular Plant Physiology) ; Villarreal Aguilar, Juan C. (Université Laval. Department of Biology) ; Widiez, Thomas (University of Geneva. Department of Plant Biology) ; Wong, Gane Ka-Shu (University of Alberta. Department of Biological Sciences) ; Wymore, Ann (Oak Ridge National Laboratory) ; Zhang, Yong (Shenzhen Huahan Gene Life Technology Co. Ltd) ; Zimmer, Aandreas D. (University of Freiburg. Faculty of Biology) ; Quatrano, Ralph S. (Washington University. Department of Biology) ; Mayer, Klaus F. X. (Technical University Munich) ; Goodstein, David (DOE Joint Genome Institute) ; Casacuberta i Suñer, Josep M. 1962- (Centre de Recerca en Agrigenòmica) ; Vandepoele, Klaas (Ghent University. Department of Plant Biotechnology and Bioinformatics) ; Reski, Ralph (University of Freiburg. Faculty of Biology) ; Cuming, Andrew C. (University of Leeds. Faculty of Biological Sciences) ; Tuskan, Gerald A. (Oak Ridge National Laboratory. Biosciences Division) ; Maumus, Florian (Institut National de la Recherche Agronomique . Unité de Recherche Génomique Info) ; Salse, Jerome (Institut national de la recherche agronomique. UMR 1095 Genetics. Diversity and Ecophysiology of Cereals) ; Schmutz, Jeremy (DOE Joint Genome Institute) ; Rensing, Stefan A. (University of Freiburg. BIOSS Centre for Biological Signalling Studies)
The draft genome of the moss model, Physcomitrella patens, comprised approximately 2000 unordered scaffolds. In order to enable analyses of genome structure and evolution we generated a chromosome-scale genome assembly using genetic linkage as well as (end) sequencing of long DNA fragments. [...]
2018 - 10.1111/tpj.13801
Plant journal, Vol. 93, issue 3 (Feb. 2018) , p. 515-533  
7.
11 p, 1.1 MB Ischemic stroke patients are biologically older than their chronological age / Soriano-Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mola-Caminal, Marina (Institut Hospital del Mar d'Investigacions Mèdiques) ; Vivanco-Hidalgo, Rosa M. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ois, Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Campello, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sayols-Baixeras, Sergi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Jiménez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Ischemic stroke is associated with aging. It is possible to predict chronological age by measuring age-related changes in DNA methylation from multiple CpG sites across the genome, known as biological age. [...]
2016 - 10.18632/aging.101028
Aging (Albany NY), Vol. 8 (august 2016) , p. 2655-2665  
8.
14 p, 4.9 MB Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs / Nogales, Vanesa (Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain) ; Reinhold, William C. (Genomics and Bioinformatics Group, Developmental Therapeutics Branch, National Cancer Institute, Bethesda, MD, USA) ; Varma, Sudhir (Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA) ; Martinez-Cardus, Anna (Institut de Recerca Biomèdica Bellvitge (IDIBELL)) ; Moutinho, Catia (Institut de Recerca Biomèdica Bellvitge (IDIBELL)) ; Moran, Sebastian (Institut de Recerca Biomèdica Bellvitge (IDIBELL)) ; Heyn, Holger (Institut de Recerca Biomèdica Bellvitge (IDIBELL)) ; Sebio, Ana (Institut d'Investigació Biomèdica Sant Pau) ; Barnadas i Molins, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Pommier, Yves (Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA) ; Esteller, Manel (Institucio Catalana de Recerca i Estudis Avançats (ICREA)) ; Universitat Autònoma de Barcelona
Platinum-derived drugs such as cisplatin and carboplatin are among the most commonly used cancer chemotherapy drugs, but very few specific molecular and cellular markers predicting differential sensitivity to these agents in a given tumor type have been clearly identified. [...]
2015 - 10.18632/oncotarget.6413
Oncotarget, Vol. 7 (november 2015) , p. 3084-3097  
9.
18 p, 2.2 MB Aberrant epigenome in -derived dopaminergic neurons from Parkinson's disease patients / Fernández-Santiago, Rubén (Universitat de Barcelona) ; Carballo-Carbajal, Iria (Vall d'Hebron Institut de Recerca (VHIR)) ; Castellano, Giancarlo (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Torrent, Roger (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Richaud, Yvonne (Biomaterials and Nanomedicine (CIBER-BBN). Centre for Networked Biomedical Research on Bioengineering) ; Sánchez-Danés, Adriana (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Vilarrasa-Blasi, Roser (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Sánchez-Pla, Alex (Vall d'Hebron Institut de Recerca (VHIR)) ; Mosquera, José Luis (Universitat de Barcelona) ; Soriano, Jordi (Universitat de Barcelona) ; López-Barneo, José (Universidad de Sevilla. Hospital Universitario Virgen del Rocío.) ; Canals, Josep M (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alberch i Vié, Jordi (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Vila Bover, Miquel (Vall d'Hebron Institut de Recerca (VHIR)) ; Consiglio, Antonella (University of Brescia and National Institute of Neuroscience) ; Martín-Subero, José I (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ezquerra, Mario (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Tolosa, Eduardo (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)) ; Universitat Autònoma de Barcelona
The epigenomic landscape of Parkinson's disease () remains unknown. We performed a genomewide methylation and a transcriptome studies in induced pluripotent stem cell ()-derived dopaminergic neurons (n) generated by cell reprogramming of somatic skin cells from patients with monogenic 2-associated (L2) or sporadic (), and healthy subjects. [...]
2015 - 10.15252/emmm.201505439
EMBO Molecular Medicine, Vol. 7, Núm. 12 (October 2015) , p. 1529-1546  
10.
11 p, 577.8 KB A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers / Diesch, Jeannine (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zwick, Anabel (Technical University Munich. Department of Medicine) ; Garz, Anne-Kathrin (German Cancer Research Center (Heidelberg, Alemanya)) ; Palau, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Götze, Katharina S. (German Cancer Research Center (Heidelberg, Alemanya))
The azanucleosides azacitidine and decitabine are currently used for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) in patients not only eligible for intensive chemotherapy but are also being explored in other hematologic and solid cancers. [...]
2016 - 10.1186/s13148-016-0237-y
Clinical epigenetics, Vol. 8 Núm. 71 (Juny 2016)  

Articles : 18 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 7 registres trobats  
1.
1 p, 2.3 MB Designing a novel methylation array for head and neck squamous cell carcinoma (HNSCC) detection / Vergara Ucin, Xabier ; Pallarès i Goitiz, Irantzu, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
2.
1 p, 738.6 KB Epigenetics as biomarker for Alzheimer's disease : a new approach to prevention, diagnosis and treatment / Martínez Ruiz, Elena ; Barquinero, J. F., (Joan Francesc), dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
3.
1 p, 642.4 KB Post-translational modifications of histones linked with gliomas : H3K27me3 (¿Methylated or demethylated?, that is the question) / Fábregas Ordóñez, Cristina ; Roque Córdova, Alicia, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Biotecnologia [815]  
4.
138 p, 2.6 MB LKB1/ AMPK / TSC2 signaling pathway alterations in non-small-cell-lung-carcinoma / de Aguirre Egaña, Itziar ; Vertino, Paula, dir. ; Rosell i Costa, Rafael, dir. ; Universitat Autònoma de Barcelona. Departament de Mitjans, Comunicació i Cultura
El gen supresor tumoral LKB1/STK11b, codifica una serina/treonina quinasa. Las mutaciones de línea germinal en LKB1 están asociadas al síndrome de Peutz-Jeghers (PJS), trastorno dominante autosómico caracterizado por el crecimiento de pólipos en el tracto gastrointestinal, y depósitos de melanina mucocutánea, aumentando el riesgo de ciertos cánceres, incluido el de pulmón. [...]
LKB1, also known as STK11b, is a serine/threonine kinase that functions as a suppressor of tumor growth. Germ line mutations in LKB1 are associated with the Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterized by benign hemartomas of the gastrointestinal tract and mucocutaneous melanin deposits and an increased risk of certain cancers, including lung. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
5.
1 p, 520.8 KB Monozygous twins discrimination in forensic medicine / Mendizuri Sánchez, Saioa ; Pereira dos Santos, Cristina Maria, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  
6.
1 p, 1.7 MB A way to solve the problem in the discrimination of monozygotic twins / Mañas García, Laura ; Pereira dos Santos, Cristina Maria, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Genètica [833]  
7.
1 p, 570.5 KB Role of the epigenetic regulation of chromatin in breast cancer / Giralt, Irina ; Roque Córdova, Alicia, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  

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