Resultats globals: 18 registres trobats en 0.02 segons.
Articles, 12 registres trobats
Documents de recerca, 6 registres trobats
Articles 12 registres trobats  1 - 10següent  anar al registre:
1.
Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach / Mármol-Sánchez, Emilio (Centre de Recerca en Agrigenòmica) ; Cirera, Susanna (University of Copenhagen. Department of Veterinary and Animal Sciences (Denmark)) ; Quintanilla, Raquel (Institut de Recerca i Tecnologia Agroalimentàries) ; Pla, Albert (University of Oslo. Department of Medical Genetics (Norway)) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica)
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we designed a comprehensive pipeline (eMIRNA) for miRNA identification in the yet poorly annotated porcine genome and demonstrated the usefulness of implementing a motif search positional refinement strategy for the accurate determination of precursor miRNA boundaries. [...]
2020 - 10.1016/j.ygeno.2019.12.005
Genomics, Vol. 112, Issue 3 (May 2020) , p. 2107-2118
2 documents
2.
16 p, 2.0 MB Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus / Sánchez Sanuy, Ferran (Centre de Recerca en Agrigenòmica) ; Peris Peris, Cristina (Centre de Recerca en Agrigenòmica) ; Tomiyama, Shiho (University of Tokyo. Biotechnology Research Center (Japan)) ; Okada, Kazunori (University of Tokyo. Biotechnology Research Center (Japan)) ; Hsing, Yue-Ie (Academia Sinica. Institute of Plant and Microrbial Biology (Taiwan)) ; San Segundo, Blanca (Centre de Recerca en Agrigenòmica) ; Campo Sánchez, Sonia (Centre de Recerca en Agrigenòmica)
Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level in eukaryotes. In rice, MIR7695 expression is regulated by infection with the rice blast fungus Magnaporthe oryzae with subsequent down-regulation of an alternatively spliced transcript of natural resistance-associated macrophage protein 6 (OsNramp6). [...]
2019 - 10.1186/s12870-019-2156-5
BMC plant biology, Vol. 19 (December 2019) , art. 563  
3.
8 p, 811.3 KB African swine fever virus does not express viral microRNAs in experimentally infected pigs / Núñez-Hernández, Fernando (Institut de Recerca i Tecnologia Agroalimentàries) ; Vera Rodríguez, Gonzalo (Centre de Recerca en Agrigenòmica) ; Sánchez Bonastre, Armando (Centre de Recerca en Agrigenòmica) ; Rodríguez, Fernando (Institut de Recerca i Tecnologia Agroalimentàries) ; Núñez, José I. (Institut de Recerca i Tecnologia Agroalimentàries)
Background: African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), a re-expanding devastating and highly lethal hemorrhagic viral disease. microRNAs (miRNAs) are a new class of small non-coding RNAs that regulate gene expression post-transcriptionally. [...]
2018 - 10.1186/s12917-018-1601-2
BMC veterinary research, Vol. 14 (September 2018) , art. 268  
4.
5 p, 173.0 KB Circulating levels of 423-5p are associated with 90 day mortality in cardiogenic shock / Jäntti, Toni (Department of Internal Medicine, University of Helsinki and Helsinki University Hospital) ; Segersvärd, Heli (Minerva Foundation Institute for Medical Research and University of Helsinki) ; Tolppanen, Heli (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ; Tarvasmäki, Tuukka (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ; Lassus, Johan (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ; Devaux, Yvan (Luxembourg Institute of Health) ; Vausort, Mélanie (Luxembourg Institute of Health) ; Pulkki, Kari (Department of Clinical Chemistry, University of Eastern Finland and Eastern Finland Laboratory Centre (ISLAB)) ; Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ; Bayes-Genis, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tikkanen, Ilkka (Division of Nephrology, University of Helsinki and Abdominal Center, Division of Nephrology, Helsinki University Hospital) ; Lakkisto, Päivi (Department of Clinical Chemistry, University of Helsinki and Department of Clinical Chemistry, Helsinki University Hospital) ; Harjola, Veli-Pekka (Division of Emergency Medicine, University of Helsinki and Department of Emergency Medicine and Services, Helsinki University Hospital) ; Universitat Autònoma de Barcelona. Departament de Medicina
The role of microRNAs has not been studied in cardiogenic shock. We examined the potential role of miR-423-5p level to predict mortality and associations of miR-423-5p with prognostic markers in cardiogenic shock. [...]
2018 - 10.1002/ehf2.12377
ESC Heart Failure, Vol. 6 (november 2018) , p. 98-102  
5.
10 p, 957.5 KB Direct and Label-Free Quantification of Micro-RNA-181a at Attomolar Level in Complex Media Using a Nanophotonic Biosensor / Huertas, César S (Institut Català de Nanociència i Nanotecnologia) ; Fariña, David (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia)
Micro-RNA signatures have emerged as advantageous biomarkers for disease prediction opening the route for the development of more direct and accurate therapies. There is an urgent need for reliable tools which can offer fast, highly sensitive, and selective detection of multiple miRNAs in complex matrices as opposed to the conventional techniques. [...]
2016 - 10.1021/acssensors.6b00162
ACS Sensors, Vol. 1, Núm. 6 (June 2016) , p. 748-756  
6.
11 p, 713.2 KB Practical data handling pipeline improves performance of qPCR-based circulating miRNA measurements / De Ronde, Maurice W.J. (University of Amsterdam) ; Ruijter,Jan M. (University of Amsterdam) ; Lanfear, David (Henry Ford Hospital. Heart and Vascular Insitute) ; Bayes Genis, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Kok, Maayke G.M. (University of Amsterdam) ; Creemers, Esther E. (University of Amsterdam) ; Pinto, Yigal M. (University of Amsterdam) ; Pinto-Sietsma, Sara-Joan (University of Amsterdam) ; Universitat Autònoma de Barcelona
Since numerous miRNAs have been shown to be present in circulation, these so-called circulating miRNAs have emerged as potential biomarkers for disease. However, results of qPCR studies on circulating miRNA biomarkers vary greatly and many experiments cannot be reproduced. [...]
2017 - 10.1261/rna.059063.116
RNA, Vol. 23 Núm. 5 (2017) , p. 811-821  
7.
9 p, 779.8 KB MicroRNAs in rice innate immunity / Baldrich, Patricia (Centre de Recerca en Agrigenòmica) ; San Segundo, Blanca (Centre de Recerca en Agrigenòmica)
MicroRNAs (miRNAs) are short regulatory non-coding RNAs that guide gene silencing in most eukaryotes. They regulate gene expression by triggering sequence-specific cleavage or translational repression of target transcripts. [...]
2016 - 10.1186/s12284-016-0078-5
Rice, Vol. 9 (Feb. 2016) , art. 6  
8.
17 p, 5.7 MB MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes / Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca ) ; París-Coderch, Laia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Jubierre, Luz (Vall d'Hebron Institut de Recerca (VHIR)) ; Martínez, Alba (Tumor Angiogenesis Group, Catalan Institute of Oncology-IDIBELL) ; Zhou, Xiangyu (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Piskareva, Olga (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ; Bray, Isabella (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ; Vidal, Isaac (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Almazán-Moga, A (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Molist, Carla (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Roma, Josep (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Bayascas Ramírez, José Ramón. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Casanovas, Oriol (Tumor Angiogenesis Group, Catalan Institute of Oncology-IDIBELLL'Hospitalet de Llobregat) ; Stallings, Raymond L. (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ; de Toledo, José Sánchez (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Gallego, Soledad (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Segura, Miguel F. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca (VHIR)
Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). [...]
2016 - 10.18632/oncotarget.7005
Oncotarget, Vol. 7 (january 2016) , p. 9271-9287  
9.
12 p, 2.2 MB MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients / De Mattos-Arruda, Leticia (Institut d'Oncologia de la Vall Hebron) ; Bottai, Giulia (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Nuciforo, Paolo (Institut d'Oncologia de la Vall Hebron) ; Di Tommaso, Luca (Division of Pathology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Giovannetti, Elisa (University of Pisa. Cancer Pharmacology Laboratory. AIRC Start-Up Unit (Italy)) ; Peg, Vicente (Hospital Universitari Vall d'Hebron) ; Losurdo, Agnese (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Pérez-Garcia, José (Institut d'Oncologia de la Vall Hebron) ; Masci, Giovanna (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Corsi, Fabio (University of Milan. Deparment of Clinical and Biomedical Sciences "Luigi Sacco" (Italy)) ; Cortés, Javier (Hospital Universitario Ramón y Cajal) ; Seoane Suárez, Joan (Institut d'Oncologia de la Vall Hebron) ; Calin, George A. (The University of Texas MD Anderson Cancer Center (USA)) ; Santarpia, Libero (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Universitat Autònoma de Barcelona
Patients with primary HER2-positive breast cancer benefit from HER2-targeted therapies. Nevertheless, a significant proportion of these patients die of disease progression due to mechanisms of drug resistance. [...]
2015 - 10.18632/oncotarget.5495
Oncotarget, Vol. 6, Num. 35 (October 2015) , p. 37269-37280  
10.
21 p, 3.3 MB Single Intracoronary Injection of Encapsulated Antagomir-92a Promotes Angiogenesis and Prevents Adverse Infarct Remodeling / Bellera, Neus (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodriguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferret, Eulalia (I+D Pierre-Fabre Ibérica S.A) ; Asín, Miguel Angel (I+D Pierre-Fabre Ibérica S.A) ; Gonzalez-Alujas, MªTeresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pérez-Rodon, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteves, Marielle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fonseca, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Toran, Nuria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ; Pérez, Amadeo (I+D Pierre-Fabre Ibérica S.A) ; Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Small and large preclinical animal models have shown that antagomir-92a-based therapy reduces early postischemic loss of function, but its effect on postinfarction remodeling is not known. In addition, the reported remote miR-92a inhibition in noncardiac organs prevents the translation of nonvectorized miR-targeted therapy to the clinical setting. [...]
2014 - 10.1161/JAHA.114.000946
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 3 (september 2014)  

Articles : 12 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 6 registres trobats  
1.
1 p, 1.8 MB Improving microRNA target prediction : a novel integrative approach using dynamic transcriptomic profiling data / Gallardo Dodd, Carlos José ; Barbadilla Prados, Antonio, dir. ; Universitat Autònoma de Barcelona. Facultat de Biociències
2019
Grau en Genètica [833]  
2.
1 p, 491.8 KB Proposal of a research project : use mesenchymal stem cell derived exosomes targeted to T cells and charged with specific miRNA as a therapeutic tool against type 1 diabetes / Vicente Rizo, Sílvia ; Roher Armentia, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2016
Grau en Bioquímica [814]  
3.
1 p, 841.5 KB The role of microRNA in endometriosis / Márquez de Haro, Aida ; Anton, Ester, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Ciències Biomèdiques [832]  
4.
172 p, 1.5 MB Caracterització de microRNAs d'interès en l'espècie porcina / Timoneda i Heredia, Oriol ; Sánchez Bonastre, Armando, dir. (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments
El descobriment dels microRNAs (miRNAS) com a nous reguladors de l'expressió gènica ha obert un nou camp en l'estudi de quin és el comportament d'aquests RNAs de mida petita i descriure en quins processos actuen i de quina manera regulen l'expressió gènica. [...]
The discovery of microRNAs (miRNAs) as novel gene expression regulators has opened a new field in the study of the roles of these small RNAs, as well as on describing in what processes they act and how they regulate gene expression. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2013  
5.
1 p, 3.0 MB MicroRNA : un paper preponderant en l'adenocarcinoma ductal de pàncrees? / Encinas Casas, Adrià ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Bioquímica [814]  
6.
1 p, 771.9 KB MiR-200 family and epithelial-mesenchymal transition in mammary glands / Ferrer Jaime, Aurora ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  

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