|
1.
|
|
|
2.
|
|
16 p, 2.0 MB |
Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus
/
Sánchez Sanuy, Ferran (Centre de Recerca en Agrigenòmica) ;
Peris Peris, Cristina (Centre de Recerca en Agrigenòmica) ;
Tomiyama, Shiho (University of Tokyo. Biotechnology Research Center (Japan)) ;
Okada, Kazunori (University of Tokyo. Biotechnology Research Center (Japan)) ;
Hsing, Yue-Ie (Academia Sinica. Institute of Plant and Microrbial Biology (Taiwan)) ;
San Segundo, Blanca (Centre de Recerca en Agrigenòmica) ;
Campo Sánchez, Sonia (Centre de Recerca en Agrigenòmica)
Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level in eukaryotes. In rice, MIR7695 expression is regulated by infection with the rice blast fungus Magnaporthe oryzae with subsequent down-regulation of an alternatively spliced transcript of natural resistance-associated macrophage protein 6 (OsNramp6). [...]
2019 -  10.1186/s12870-019-2156-5
BMC plant biology, Vol. 19 (December 2019) , art. 563
|
|
|
3.
|
|
|
4.
|
|
5 p, 173.0 KB |
Circulating levels of 423-5p are associated with 90 day mortality in cardiogenic shock
/
Jäntti, Toni (Department of Internal Medicine, University of Helsinki and Helsinki University Hospital) ;
Segersvärd, Heli (Minerva Foundation Institute for Medical Research and University of Helsinki) ;
Tolppanen, Heli (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ;
Tarvasmäki, Tuukka (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ;
Lassus, Johan (Department of Cardiology, University of Helsinki and Heart and Lung Center, Helsinki University Hospital) ;
Devaux, Yvan (Luxembourg Institute of Health) ;
Vausort, Mélanie (Luxembourg Institute of Health) ;
Pulkki, Kari (Department of Clinical Chemistry, University of Eastern Finland and Eastern Finland Laboratory Centre (ISLAB)) ;
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ;
Bayes-Genis, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tikkanen, Ilkka (Division of Nephrology, University of Helsinki and Abdominal Center, Division of Nephrology, Helsinki University Hospital) ;
Lakkisto, Päivi (Department of Clinical Chemistry, University of Helsinki and Department of Clinical Chemistry, Helsinki University Hospital) ;
Harjola, Veli-Pekka (Division of Emergency Medicine, University of Helsinki and Department of Emergency Medicine and Services, Helsinki University Hospital) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The role of microRNAs has not been studied in cardiogenic shock. We examined the potential role of miR-423-5p level to predict mortality and associations of miR-423-5p with prognostic markers in cardiogenic shock. [...]
2018 - 10.1002/ehf2.12377
ESC Heart Failure, Vol. 6 (november 2018) , p. 98-102
|
|
|
5.
|
|
|
6.
|
|
11 p, 713.2 KB |
Practical data handling pipeline improves performance of qPCR-based circulating miRNA measurements
/
De Ronde, Maurice W.J. (University of Amsterdam) ;
Ruijter,Jan M. (University of Amsterdam) ;
Lanfear, David (Henry Ford Hospital. Heart and Vascular Insitute) ;
Bayes Genis, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Kok, Maayke G.M. (University of Amsterdam) ;
Creemers, Esther E. (University of Amsterdam) ;
Pinto, Yigal M. (University of Amsterdam) ;
Pinto-Sietsma, Sara-Joan (University of Amsterdam) ;
Universitat Autònoma de Barcelona
Since numerous miRNAs have been shown to be present in circulation, these so-called circulating miRNAs have emerged as potential biomarkers for disease. However, results of qPCR studies on circulating miRNA biomarkers vary greatly and many experiments cannot be reproduced. [...]
2017 - 10.1261/rna.059063.116
RNA, Vol. 23 Núm. 5 (2017) , p. 811-821
|
|
|
7.
|
|
|
8.
|
|
17 p, 5.7 MB |
MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes
/
Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca ) ;
París-Coderch, Laia (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Jubierre, Luz (Vall d'Hebron Institut de Recerca (VHIR)) ;
Martínez, Alba (Tumor Angiogenesis Group, Catalan Institute of Oncology-IDIBELL) ;
Zhou, Xiangyu (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Piskareva, Olga (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ;
Bray, Isabella (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ;
Vidal, Isaac (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Almazán-Moga, A (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Molist, Carla (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Roma, Josep (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Bayascas Ramírez, José Ramón. (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Casanovas, Oriol (Tumor Angiogenesis Group, Catalan Institute of Oncology-IDIBELLL'Hospitalet de Llobregat) ;
Stallings, Raymond L. (Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland and National Children's Research Centre Our Lady's Children's Hospital) ;
de Toledo, José Sánchez (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Gallego, Soledad (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Segura, Miguel F. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ;
Universitat Autònoma de Barcelona.
Vall d'Hebron Institut de Recerca (VHIR)
Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). [...]
2016 - 10.18632/oncotarget.7005
Oncotarget, Vol. 7 (january 2016) , p. 9271-9287
|
|
|
9.
|
|
12 p, 2.2 MB |
MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients
/
De Mattos-Arruda, Leticia (Institut d'Oncologia de la Vall Hebron) ;
Bottai, Giulia (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ;
Nuciforo, Paolo (Institut d'Oncologia de la Vall Hebron) ;
Di Tommaso, Luca (Division of Pathology. IRCCS Humanitas Clinical and Research Institute (Italy)) ;
Giovannetti, Elisa (University of Pisa. Cancer Pharmacology Laboratory. AIRC Start-Up Unit (Italy)) ;
Peg, Vicente (Hospital Universitari Vall d'Hebron) ;
Losurdo, Agnese (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ;
Pérez-Garcia, José (Institut d'Oncologia de la Vall Hebron) ;
Masci, Giovanna (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ;
Corsi, Fabio (University of Milan. Deparment of Clinical and Biomedical Sciences "Luigi Sacco" (Italy)) ;
Cortés, Javier (Hospital Universitario Ramón y Cajal) ;
Seoane Suárez, Joan (Institut d'Oncologia de la Vall Hebron) ;
Calin, George A. (The University of Texas MD Anderson Cancer Center (USA)) ;
Santarpia, Libero (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ;
Universitat Autònoma de Barcelona
Patients with primary HER2-positive breast cancer benefit from HER2-targeted therapies. Nevertheless, a significant proportion of these patients die of disease progression due to mechanisms of drug resistance. [...]
2015 - 10.18632/oncotarget.5495
Oncotarget, Vol. 6, Num. 35 (October 2015) , p. 37269-37280
|
|
|
10.
|
|
21 p, 3.3 MB |
Single Intracoronary Injection of Encapsulated Antagomir-92a Promotes Angiogenesis and Prevents Adverse Infarct Remodeling
/
Bellera, Neus (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodriguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ferret, Eulalia (I+D Pierre-Fabre Ibérica S.A) ;
Asín, Miguel Angel (I+D Pierre-Fabre Ibérica S.A) ;
Gonzalez-Alujas, MªTeresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pérez-Rodon, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteves, Marielle (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fonseca, Carla (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Toran, Nuria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garcia del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ;
Pérez, Amadeo (I+D Pierre-Fabre Ibérica S.A) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Small and large preclinical animal models have shown that antagomir-92a-based therapy reduces early postischemic loss of function, but its effect on postinfarction remodeling is not known. In addition, the reported remote miR-92a inhibition in noncardiac organs prevents the translation of nonvectorized miR-targeted therapy to the clinical setting. [...]
2014 - 10.1161/JAHA.114.000946
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 3 (september 2014)
|
|
visitant ::
identificació
alerta personal via correu electrònic o subscribiu-vos al 
canal RSS.
