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11 p, 458.4 KB |
Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer
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Yoshino, Takayuki (National Cancer Center Hospital East) ;
André, Thierry (Sorbonne University) ;
Kim, Tae Won (University of Ulsan) ;
Yong, Wei Peng (National University Cancer Institute) ;
Shiu, Kai-Keen (University College Hospital) ;
Jensen, Benny Vittrup (Herlev and Gentofte Hospital) ;
Jensen, Lars Henrik (University Hospital of Southern Denmark) ;
Punt, Cornelis J. A. (University Medical Center Utrecht) ;
Smith, Denis (Hôpital Haut-Lévêque) ;
García-Carbonero, Rocío (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ;
Alcaide-Garcia, Julia (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Gibbs, Peter (Western Hospital) ;
de la Fouchardiere, Christelle (Centre Léon Bérard) ;
Rivera, Fernando (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Elez, Elena (Vall d'Hebron Institut d'Oncologia) ;
Le, Dung T. (Johns Hopkins Medicine) ;
Adachi, Noriaki (Merck (Estats Units d'Amèrica)) ;
Fogelman, David (Merck(Estats Units d'Amèrica)) ;
Marinello, Patricia (Merck (Estats Units d'Amèrica)) ;
Diaz, Luis A. (Memorial Sloan Kettering Cancer Center) ;
Universitat Autònoma de Barcelona
The phase 3 KEYNOTE-177 study evaluated pembrolizumab versus chemotherapy with or without bevacizumab or cetuximab in patients with newly diagnosed, microsatellite-instability-high (MSI-H)/mismatch-repair-deficient (dMMR) metastatic colorectal cancer (mCRC). [...]
2022 -  10.1111/cas.15650
Cancer Science, Vol. 114 (december 2022) , p. 1026-1036
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16 p, 2.2 MB |
Host-driven subspeciation in the hedgehog fungus, Trichophyton erinacei, an emerging cause of human dermatophytosis
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Čmoková, A. (Charles University. Academy of Sciences of the Czech Republic) ;
Kolařík, M. (Academy of Sciences of the Czech Republic) ;
Guillot, J. (École nationale vétérinaire d'Alfort.) ;
Risco-Castillo, V. (École nationale vétérinaire d'Alfort) ;
Cabañes Sáenz, Francisco Javier (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Nenoff, P. (Laboratory of Medical Microbiology) ;
Uhrlaß, S. (Laboratory of Medical Microbiology) ;
Dobiáš, R. (Public Health Institute in Ostrava. University of Ostrava) ;
Mallátová, N. (Hospital České Budě-jovice) ;
Yaguchi, T. (Chiba University) ;
Kano, R. (Teikyo University) ;
Kuklová, I. (Charles University) ;
Lysková, P. (Laboratory of Mycology) ;
Mencl, K. (Pardubice Regional Hospital) ;
Hamal, P. (Palacký University Olomouc) ;
Peano, A. (Università degli Studi di Torino) ;
Hubka, V. (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Trichophyton erinacei is a main cause of dermatophytosis in hedgehogs and is increasingly reported from human infections worldwide. This pathogen was originally described in the European hedgehog (Erinaceus europaeus) but is also frequently found in the African four-toed hedgehog (Atelerix albiventris), a popular pet animal worldwide. [...]
2022 - 10.3767/persoonia.2023.48.06
Persoonia: Molecular Phylogeny and Evolution of Fungi, Vol. 48 (2022) , p. 203-208
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5 p, 829.6 KB |
First description of sarcoptic mange in an Iberian hare (Lepus granatensis)
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Cardells-Peris, Jesús (Universitat Autònoma de Barcelona. Grup de Recerca Wildlife Ecology & Health) ;
Lizana, Victor (Universitat Autònoma de Barcelona. Grup de Recerca Wildlife Ecology & Health) ;
Martí-Marco, Alba (Universidad CEU Cardenal Herrera. Servicio de Análisis, Investigación, Gestión de Animales Silvestres) ;
Lavín González, Santiago (Universitat Autònoma de Barcelona. Grup de Recerca Wildlife Ecology & Health) ;
Velarde, Roser (Universitat Autònoma de Barcelona. Grup de Recerca Wildlife Ecology & Health) ;
Rossi, Luca (Università degli Studi di Torino. Dipartimento di Scienze Veterinarie) ;
Moroni, Barbara (Università degli Studi di Torino. Dipartimento di Scienze Veterinarie)
The Iberian hare (Lepus granatensis) is a popular small game species in the Iberian Peninsula, and it has never been reported to be affected by sarcoptic mange. An adult female Iberian hare with overt skin lesions on forelimbs and ventral thorax, suggestive of sarcoptic mange, was culled in Quart de les Valls municipality in the Valencian Community, Spain, in 2019. [...]
2021 - 10.1016/j.crpvbd.2021.100021
Current Research in Parasitology & Vector-borne Diseases, Vol. 1 (march 2021)
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25 p, 3.4 MB |
Getting off to a good start? Genetic evaluation of the ex situ conservation project of the Critically Endangered Montseny brook newt (Calotriton arnoldi)
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Valbuena-Ureña, Emilio (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Soler Membrives, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Steinfartz, Sebastian (Technische Universität Braunschweig. Department of Evolutionary Biology) ;
Alonso, Mònica (Servei Català de la Fauna. Centre de Fauna Salvatge de Torreferrussa) ;
Carbonell, Francesc (Servei Català de la Fauna. Centre de Fauna Salvatge de Torreferrussa) ;
Larios-Martín, Raquel (Servei Català de la Fauna. Centre de Fauna Salvatge de Torreferrussa) ;
Obon, Elena (Servei Català de la Fauna. Centre de Fauna Salvatge de Torreferrussa) ;
Carranza, Salvador (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Ex situ management strategies play an important role in the conservation of threatened species when the wild survival of the species cannot be ensured. Molecular markers have become an outstanding tool for the evaluation and management of captive breeding programs. [...]
2017 - 10.7717/peerj.3447
PeerJ, Vol. 5 (June 2017) , art. e3447
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17 p, 898.8 KB |
Quantifying temporal change in plant population attributes : insights from a resurrection approach
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Gómez, Rocío (Estación Biológica de Doñana. Departamento de Ecología Integrativa) ;
Méndez-Vigo, Belén (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología. Departamento de Genética Molecular de Plantas) ;
Marcer, Arnald (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Alonso-Blanco, Carlos (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología. Departamento de Genética Molecular de Plantas) ;
Picó, Xavier (Estación Biológica de Doñana. Departamento de Ecología Integrativa)
Rapid evolution in annual plants can be quantified by comparing phenotypic and genetic changes between past and contemporary individuals from the same populations over several generations. Such knowledge will help understand the response of plants to rapid environmental shifts, such as the ones imposed by global climate change. [...]
2018 - 10.1093/aobpla/ply063
AoB Plants, Vol. 10, issue 5 (Oct. 2018) , art. ply063
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9 p, 435.9 KB |
Prediction of overall survival in stage II and III colon cancer beyond TNM system : a retrospective, pooled biomarker study
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Dienstmann, Rodrigo. (Hospital Universitari Vall d'Hebron) ;
Mason, M. J. (Computational Oncology, Sage Bionetworks, Seattle, USA) ;
Sinicrope, F. A. (Mayo Clinic and Mayo Comprehensive Cancer Center, Rochester, USA) ;
Phipps, A. I. (Fred Hutchinson Cancer Research Center, Seattle, USA) ;
Tejpar, Sabine (University Hospitals Gasthuisberg (Leuven, Bélgica)) ;
Nesbakken, A. (Oslo University Hospital (Oslo, Noruega)) ;
Danielsen, S. A. (Oslo University Hospital (Oslo, Noruega)) ;
Sveen, A. (Oslo University Hospital (Oslo, Noruega)) ;
Buchanan, Daniel D (The University of Melbourne) ;
Clendenning, M. (The University of Melbourne) ;
Rosty, C. (The University of Melbourne) ;
Bot, Brian M (Computational Oncology, Sage Bionetworks, Seattle, USA) ;
Alberts, S. R. (Mayo Clinic and Mayo Comprehensive Cancer Center, Rochester, USA) ;
Milburn Jessup, J. (National Cancer Institute (Rockville, Estats Units d'Amèrica)) ;
Lothe, R. A. (Oslo University Hospital (Oslo, Noruega)) ;
Delorenzi, Mauro (SIB Swiss Institute Bioinformatics, Lausanne, Switzerland) ;
Newcomb, P. A. (Fred Hutchinson Cancer Research Center, Seattle, USA) ;
Sargent, D. (Mayo Clinic, Rochester, USA) ;
Guinney, J. (Computational Oncology, Sage Bionetworks, Seattle, USA) ;
Universitat Autònoma de Barcelona
TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent the molecular markers microsatellite instability (MSI) and mutations in BRAF or KRAS improve prognostic estimation in multivariable models that include detailed clinicopathological annotation. [...]
2017 - 10.1093/annonc/mdx052
Annals of oncology, Vol. 28 (february 2017) , p. 1023-1031
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14 p, 545.1 KB |
Syntenic relationships between cucumber(Cucumis sativus L.) and melon (C. melo L.) chromosomes as revealed by comparative genetic mapping
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Dawei, Li (Northwestern University. Horticulture College) ;
Cuevas, Hugo E. (University of Wisconsin. Horticulture Department) ;
Yang, Luming (University of Wisconsin. Horticulture Department) ;
Yuhong, Li (Northwestern University. Horticulture College) ;
Garcia-Mas, Jordi (Centre de Recerca en Agrigenòmica) ;
Zalapa, Juan (University of Wisconsin. Horticulture Department) ;
Staub, Jack E. (Forage and Range Research Laboratory (U.S.)) ;
Luan, Feishi (Northwestern University. Horticulture College) ;
Reddy, Umesh (West Virginia State University. Department of Biology) ;
He, Xiaoming (University of Wisconsin. Horticulture Department) ;
Gong, Zhenhui (Northwestern University. Horticulture College) ;
Weng, Yiqun (University of Wisconsin. Horticulture Department)
Background: Cucumber, Cucumis sativus L. (2n = 2 × = 14) and melon, C. melo L. (2n = 2 × = 24) are two important vegetable species in the genus Cucumis (family Cucurbitaceae). Both species have an Asian origin that diverged approximately nine million years ago. [...]
2011 - 10.1186/1471-2164-12-396
BMC genomics, Vol. 12 (2011) , art. 396
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22 p, 522.6 KB |
Genetic diversity measures of local European beef cattle breeds for conservation purposes
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Cañón Ferreras, Javier (Universidad Complutense de Madrid. Facultad de Veterinaria) ;
Alexandrino, Paolo (Faculdade Ciencias Porto (Porto, Portugal)) ;
Bessa, Isabel (Faculdade Ciencias Porto (Porto, Portugal)) ;
Carleos, Carlos (Universidad de Oviedo. Facultad de Ciencias) ;
Carretero, Yolanda (Universidad Complutense de Madrid. Facultad de Veterinaria) ;
Dunner, Susana (Universidad Complutense de Madrid. Facultad de Veterinaria) ;
Ferran, Nuno (Faculdade Ciencias Porto (Porto, Portugal)) ;
Garcia, David (Universidad Complutense de Madrid. Facultad de Veterinaria) ;
Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Laloë, Denis (Institut National de la Recherche Agronomique (França)) ;
Pereira, Albano (Faculdade Ciencias Porto (Porto, Portugal)) ;
Sánchez Bonastre, Armando (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Moazami-Goudarzi, Katayoun (Institut National de la Recherche Agronomique (França))
This study was undertaken to determine the genetic structure, evolutionary relationships, and the genetic diversity among 18 local cattle breeds from Spain, Portugal, and France using 16 microsatellites. [...]
2001 - 10.1186/1297-9686-33-3-311
Genetics, selection, evolution, Vol. 33 (May 2001) , p. 311-332
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10 p, 241.2 KB |
Genetic diversity in Spanish donkey breeds using microsatellite DNA markers
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Aranguren Méndez, José Atilio (Universidad del Zulia. Departamento de Producción Animal (Maracaibo, Veneçuela)) ;
Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Gómez, Mariano (Diputación Foral de Bizkaia. Servicio de Ganadería)
Genetic diversity at 13 equine microsatellite loci was compared in five endangered Spanish donkey breeds: Andaluza, Catalana, Mallorquina, Encartaciones and Zamorano-Leonesa. All of the equine microsatellites used in this study were amplified and were polymorphic in the domestic donkey breeds with the exception of HMS1, which was monomorphic, and ASB2, which failed to amplify. [...]
2001 - 10.1186/1297-9686-33-4-433
Genetics, selection, evolution, Vol. 33 (July 2001) , p. 433-442
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